Search clinical trials for: Adenine phosphoribosyltransferase deficiency

Total 9671 results

National Human Genome Research Institute (NHGRI)

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions

United States
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
Mayo Clinic

Recruiting

Prospective Research Rare Kidney Stones (ProRKS) (ProRKS)

Cystinuria | Hyperoxaluria | Dent Disease | Lowe Syndrome | Adenine Phosphoribosyltransferase Deficiency

United States, Canada, Iceland, Israel
Landspitali University Hospital
Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases...

Completed

Effect of Allopurinol and Febuxostat on Urinary 2,8-Dihydroxyadenine Excretion

Adenine Phosphoribosyltransferase Deficiency

Iceland
RTI International
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Enrolling by invitation

Early Check: Expanded Screening in Newborns

Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Recruiting

Rare Kidney Stone Consortium Patient Registry (RKSC)

Cystinuria | Primary Hyperoxaluria | Dent Disease | APRT Deficiency

United States, Iceland
NYU Langone Health
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Health-related Quality of Life in Rare Kidney Stone

Cystinuria | Primary Hyperoxaluria | Dent Disease | Adenine Phosphoribosyl Transferase Deficiency

United States, Iceland
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Several Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Used Indinavir

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effectiveness of Nelfinavir and Efavirenz, Used Alone or Together, Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Acceptability of the Anti-Microbe Vaginal Gel, PMPA Gel

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women

HIV Infections

South Africa, Uganda, Zimbabwe
National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Adherence and Acceptability to and Blood Levels of Tenofovir Gel and Tablets in HIV Uninfected Women

HIV Infections

United States, Uganda, South Africa
National Institute of Allergy and Infectious Diseases...

Terminated

Biochemical Response to Interferon-Gamma in Subjects With Specific Gene Mutation in Chronic Granulomatous Disease

IFN-Gamma Therapy | CGD Gene Mutation | CGD Response to IFNg | CGD - Chronic Granulomatous Disease | Immunodeficiency Disease

United States
CONRAD
Gilead Sciences; International Partnership for Microbicides, Inc.

Completed

Pharmacokinetic Study of the Vaginal Microbicide Agent 1% Tenofovir Gel

HIV Infections

United States, Dominican Republic
Gilead Sciences

Completed

A Study of Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Been Treated With Anti-HIV Drugs

HIV Infections

United States
Merck Sharp & Dohme LLC

Completed

Indinavir Plus Efavirenz Plus Adefovir Dipivoxil in HIV-Infected Patients Who Have Not Had Success With Nelfinavir

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs

HIV Infections

United States, Puerto Rico
Gilead Sciences

Unknown

The Safety of Tenofovir Disoproxil Fumarate Taken With Other Anti-HIV Drugs to Treat HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Unknown

Safety and Effectiveness of Adding Adefovir Dipivoxil and Nelfinavir to the Anti-HIV Therapy of HIV-Infected Children

HIV Infections

United States
Gilead Sciences

Completed

A Phase II, Stratified, Randomized, Double-Blind, Multi-Center Study of the Safety and Efficacy of Adefovir Dipivoxil (ADF) at Two Dose Levels in Triple Combination Therapies With Protease Inhibitors (PI) and Nucleoside Reverse Transcriptase Inhibitors (RTI) for the Treatment of HIV-Infected Patient

HIV Infections

United States, Puerto Rico
Gilead Sciences

Completed

A Phase I/II Study of the Safety, Tolerance, and Pharmacokinetics of 9-(2-Phosphonylmethoxyethyl)Adenine ( PMEA; Adefovir ) in Patients With Advanced HIV Disease.

HIV Infections

United States
Gilead Sciences

Completed

A Study of PMPA in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Zidovudine Plus Adefovir in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

Phase I Study of the Safety, Tolerance, and Pharmacokinetics of 9-[2-(Bispivaloyloxymethyl)Phosphonylmethoxyethyl]Adenine (Bis-POM PMEA; Adefovir Dipivoxil) in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Unknown

Tenofovir Disoproxil Fumarate in HIV-Infected Patients Who Have Not Had Success With Other Anti-HIV Drug Combinations

HIV Infections

United States
Gilead Sciences

Completed

Tenofovir Disoproxil Fumarate (TDF) in HIV-1 Patients Who Have Never Taken Anti-HIV Drugs

HIV Infections

United States
Gilead Sciences

Completed

A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Adefovir Dipivoxil When Added to Standard Antiretroviral Therapy for the Treatment of HIV-Infected Patients With CD4 Cell Counts >= 200/mm3

HIV Infections

United States
Gilead Sciences

Completed

The Safety and Effectiveness of Bis-POM PMEA in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Unknown

The Safety and Effectiveness of PMPA Prodrug in HIV-Infected Patients

HIV Infections

United States
Gilead Sciences

Completed

Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations

HIV Infections

United States
L-Nutra Inc
University of Tennessee Medical Center

Recruiting

Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies

Chemotherapy Effect | Fasting, Intermittent | Cancer, Ovarian | Calorie Deficiency

United States
Privatpraxis für Knie- und Schulterchirurgie

Recruiting

Sterile Allogeneic Spongioflex® Allograft as Partial Meniscal Replacement After Incomplete Meniscal Loss

Meniscus Lesion

Germany
Liaquat University of Medical & Health Sciences

Not yet recruiting

Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation in Healthy Adults With B12 Deficiency

Vitamin B 12 Deficiency

Pakistan
University of Missouri-Columbia
Gilead Sciences

Recruiting

Accelerated ART Initiation for PWHIV Who Are Out of Care (ACCELERATE)

HIV Infections | ART | Noncompliance, Patient

United States
McGill University Health Centre/Research Institute...

Not yet recruiting

The Antiretroviral Speed Access Program Switch (ASAP-Switch) Study

HIV Infections

Canada
Apollo Therapeutics Ltd

Not yet recruiting

A Study to Investigate APL-4098 Alone and/or in Combination With Azacitidine in R/R AML and High-Risk MDS

Myelodysplastic Syndrome With Excess Blasts | Acute Myeloid Leukemia, in Relapse | Acute Myeloid Leukemia Refractory | Myelodysplastic Syndrome Acute Myeloid Leukemia
Cairo University

Not yet recruiting

Relationship Between Vitamins Deficiency and Caries Experience Among a Group of Egyptian Children

Dental Caries | Vitamin Deficiency
Milton S. Hershey Medical Center

Not yet recruiting

Estrogen Deficiency on Cardiovascular Risk

Cardiovascular Diseases | Postmenopausal Symptoms
University of Stellenbosch
University College London Hospitals; University of Copenhagen; Imperial College... and other collaborators

Not yet recruiting

Harnessing Male Peer Networks to Enhance Engagement With HIV Prevention (IMPERATIVE)

HIV Infections
Linnaeus University
World Anti-Doping Agency; Swedish Research Council for Sport Science; Swedish...

Recruiting

Relative Energy Deficiency in Sports (REDs) in Swedish Athletes (REDs-Sweden)

Eating Disorders | RED S

Sweden
University of California, Los Angeles
University of North Carolina, Chapel Hill; University of California, Irvine; Florida... and other collaborators

Recruiting

Exploring, Predicting, and Intervening on Long-term Viral Suppression Electronically (EPI-LoVE)

HIV Infections

United States
ViiV Healthcare

Not yet recruiting

A Study to Investigate the Effect of Food on the Bioavailability of a Capsid Inhibitor (CAI) in Male and Female Healthy Participants

HIV Infections
bioLytical Laboratories

Not yet recruiting

A Study to Evaluate the Performance, Usability, and Result Interpretation of INSTI® HIV Self-Test

Human Immunodeficiency Virus I Infection | Human Immunodeficiency Virus II Infection
The Cooper Health System
Won Sook Chung Foundation

Not yet recruiting

Emulated Study of Vitamin D Correction vs Non-Correction

Vitamin D Deficiency
Arrowhead Regional Medical Center

Recruiting

Intravenous Iron Versus Oral Iron for the Treatment of Iron Deficiency Anemia (IDA)

Iron Deficiency Anemia of Pregnancy

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

Bladder Cancer

China
Ibrahim Halil Sahin
GlaxoSmithKline

Not yet recruiting

Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers

MMR-D/MSI-H Colorectal Cancers

United States
McGill University
Global Affairs Canada; World Vision Canada

Not yet recruiting

Evaluation of REACTS-IN, an Intervention to Improve Nutrition, Hygiene, and Sexual and Reproductive Health Services (REACTS-IN)

Stunting | Diet; Deficiency | Empowerment | Acceptability of Health Care | Gender Equality

Bangladesh, Kenya, Tanzania
Octapharma

Not yet recruiting

Phase 3 Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Acute Hereditary Angio Edema
7 Hills Pharma, LLC

Not yet recruiting

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy

Melanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditions

United States

Search clinical trials for: Adenine phosphoribosyltransferase deficiency

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