Search clinical trials for: Airway inflammation

Total 11350 results

University Hospital, Antwerp

Not yet recruiting

The Role of VOCs, Airway Mucins and Airway Microbiome in Bronchopulmonary Dysplasia (INFANCY)

Bronchopulmonary Dysplasia
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Dupilumab Efficacy on Bronchial Inflammation, Small Airways Disfunction and Mucous Secretion (DEBORA)

Asthma; Eosinophilic

Spain
Asger Sverrild
AstraZeneca; University Hospitals, Leicester; University Hospital, Antwerp

Recruiting

Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPD (UPSTREAM-COPD)

COPD | COPD Exacerbation | Immune System Disorder | Airway Disease | COPD Bronchitis

United Kingdom, Belgium, Denmark
University of Arizona
Boehringer Ingelheim

Recruiting

Effect of CPAP on Abnormal Gastroesophageal Reflux and Lung Inflammation in IPF

Obstructive Sleep Apnea | Gastro Esophageal Reflux | Idiopathic Pulmonary Fibrosis

United States
Sanofi
Regeneron Pharmaceuticals

Recruiting

Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD (AERIFY-3)

Chronic Obstructive Pulmonary Disease

United States, Netherlands, Belgium, Denmark, Germany, United Kingdom, Brazil
Makerere University
Charite University, Berlin, Germany

Not yet recruiting

Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort (HLM)

HIV Infections | COPD | Respiratory Disease

Uganda
Hofseth Biocare ASA
Møre og Romsdal Hospital Trust; Trondheim University Hospital

Recruiting

Unrefined Salmon Oil as Dietary Supplement in Adult Asthmatics

Asthma

Norway
Medical University of Vienna

Recruiting

Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps (PREMIUM)

Asthma | Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Chronic Rhinosinusitis With Nasal Polyps

Austria
The First Affiliated Hospital of Guangzhou Medical...
Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Hospital... and other collaborators

Not yet recruiting

The Value of FeNO in Predicting Airway Eosinophilic Inflammation (FeNO-Eos)

Biomarkers | Airway Inflammation

China
Helsinki University Central Hospital

Recruiting

Aggravated Airway Inflammation: Research on Biological Treatment (Mepolizumab) (AirGOs-biol)

Chronic Rhinosinusitis With Nasal Polyps | Asthma, Aspirin-Induced

Finland
University Hospital, Geneva

Recruiting

Muscle Ultrasound Study in Shock Patients (MUSiShock)

Septic Shock

Switzerland
University of Minnesota

Recruiting

Treatment of ARDS With Instilled T3 (ARDS+T3)

Thyroid | Pulmonary Edema | ARDS, Human | Lung Inflammation | Lung, Wet

United States
University Hospital Inselspital, Berne
Centre Hospitalier Universitaire Vaudois; Kantonsspital Aarau; University Children... and other collaborators

Recruiting

Impact of Early Lung Physiology, Viral Infections and the Microbiota on the Development and Progression of Lung Disease in Children With Cystic Fibrosis (SCILD)

Confirmed Diagnosis of Cystic Fibrosis

Switzerland
University of North Carolina, Chapel Hill
United States Department of Defense

Recruiting

Woodsmoke Particulate + Prednisone (Smokisone)

Airway Inflammation

United States
Tampere University Hospital

Recruiting

Small Airway Inflammation and Dysfunction in Different Asthma Phenotypes

Asthma

Finland
Andrew D. Luster, M.D.,Ph.D.
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Lung-Resident Memory Th2 Cells in Asthma

Asthma, Allergic

United States
Peter Wijkstra

Recruiting

The Effects of Nocturnal Non-invasive Ventilation in Stable COPD (RECAPTURE)

Noninvasive Ventilation

Netherlands
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Recruiting

To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This Susceptibility (SmokeScreen)

Allergic Asthma | Airway Inflammation

United States
Guangzhou Institute of Respiratory Disease

Recruiting

Sputum Microbiota and the Association With Clinical Parameters in Steady-state, Acute Exacerbation and Convalescence of Bronchiectasis (BISER-2)

Bronchiectasis

China
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Longitudinal Observational Study of Severe Asthma

Asthma

United States
Benjamin Medoff
National Institutes of Health (NIH); U.S. Army Medical Research and Development...

Recruiting

Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation

Asthma

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 Inflammation (BOREAS)

Chronic Obstructive Pulmonary Disease

Spain, Argentina, China, Mexico, Canada, Ukraine, Israel, Italy, Czechia, Korea, Republic of, Bulgaria, Chile, Denmark, Finland, Germany, Hungary, Japan, Poland, Romania, Russian Federation, Slovakia, Sweden, Turkey, United States
Value Outcomes Ltd.
AstraZeneca

Completed

Characteristics of Type 2- High Inflammatory Endotype of Asthma Using New Biomarkers From Peripheral Blood and Exhaled Air and Its Effect on the Outcome of Therapy

Asthma, Bronchial | Bronchial Asthma | Asthma Chronic | Asthma; Eosinophilic

Czechia
Sanna Salmi
University of Helsinki

Active, not recruiting

Aggravated Airway Inflammation: Research on Genomics and Optimal Medical Care (AirGOs-medical) (AirGOs-med)

Chronic Rhinosinusitis (Diagnosis)

Finland
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Completed

A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults (SmokeyT)

Asthma | Airway Inflammation

United States
McMaster University
St. Joseph's Healthcare Hamilton; Ontario Lung Association; Cyclomedica Australia...

Enrolling by invitation

Ventilation Heterogeneity Prior to Lung Resection

Lung Cancer

Canada
University Hospital, Antwerp

Enrolling by invitation

Viral Infections and Airway Microbiome in Young Children With Cystic Fibrosis

Respiratory Viral Infection | Respiratory Morbidity | Cystic Fibrosis in Children | Respiratory Bacterial Infection | Inflammation Lungs

Belgium
St Vincent's University Hospital, Ireland
University College Dublin; Health Research Board, Ireland

Completed

Effect of Liraglutide vs CPAP on Cardiometabolic Outcomes in Obstructive Sleep Apnea

Sleep Apnea, Obstructive

Ireland
Anders Røsland
Uppsala University; European Research Council

Enrolling by invitation

Bergen Oral Respiratory Intervention Study (BORALIS)

Periodontitis | Airway Obstruction | Lung Inflammation

Norway
University of North Carolina, Chapel Hill
United States Department of Defense

Enrolling by invitation

Woodsmoke Particulate + Hypertonic Saline (Smokeysal)

Airway Inflammation

United States
Instituto de Investigacion Sanitaria La Fe
Sociedad Valenciana de Neumología

Completed

Effects of Azithromycin on Airway Oxidative Stress Markers in Patients With Bronchiectasis

Bronchiectasis

Spain
Helsinki University Central Hospital

Active, not recruiting

Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative)

Asthma | Nasal Polyps | Aspirin Sensitivity | Sinusitis, Chronic

Finland, Netherlands
Mansoura University Hospital
Azza Tarik Eliwa; Ahmed Elsayed Mansour; Taha Taha Abdelgawad; Ahmed Mohamed Fouda

Completed

Airway Inflammation, Small Airways Dysfunction, and Frequency of Exacerbations in COPD

COPD Exacerbation Acute

Egypt
University of Nebraska
VA Nebraska Western Iowa Health Care System

Completed

Airway Macrophages and Sputum Milieu in Adult Subjects With Airflow Obstruction

Pulmonary Disease, Chronic Obstructive | Occupational Diseases | Tobacco Use Disorder | Bronchitis, Chronic

United States
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

The Effect of Dupilumab on Lung Inflammation and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe Asthma (VESTIGE)

Asthma

Portugal, Ukraine, Spain, Taiwan, Sweden, United States, Bulgaria, Denmark, France, Italy, Romania, Saudi Arabia, United Kingdom
Herlev and Gentofte Hospital

Completed

Impact of LTBI Treatment on Glucose Tolerance and Chronic Inflammation

Diabetes Mellitus, Type 2 | Latent Tuberculosis

Denmark
Foresee Pharmaceuticals Co., Ltd.

Completed

The Effect of FP-025, a MMP-12 Inhibitor, on Allergen-induced Airway Responses and Airway Inflammation in Mild Eosinophilic House Dust Mite (HDM)-Allergic Asthma

Asthma, COPD

Netherlands
Yale University

Active, not recruiting

Microbiome Acquisition and Progression of Inflammation and Airway Disease in Infants and Children With Cystic Fibrosis

Cystic Fibrosis

United States
AstraZeneca

Completed

An Exploratory Study to Characterise Changes in Airway Inflammation, Symptoms, Lung Function and Reliever Use in Adult Asthma Patients

Asthma | Airway Inflammation

United Kingdom
University Hospital, Grenoble
Centre Hospitalier Universitaire de Saint Etienne; University Hospital, Clermont-Ferrand and other collaborators

Terminated

Cardiovascular Impairments and Obstructive Sleep Apnea Syndrome (INFRASAS)

Obstructive Sleep Apnea Syndrome | Subclinical Cardiovascular Impairments

France
Prescott Woodruff
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study of the Inflammation and Airway Changes That Occur After Exposure to Allergen in Asthmatics (ACE)

Asthma

United States
University of California, San Francisco

Active, not recruiting

Innate Immunity in Ozone-induced Airway Inflammation in COPD (CO3PD)

Pulmonary Disease, Chronic Obstructive | COPD Exacerbation | Pollution; Exposure | Airway Disease | Pollution Related Respiratory Disorder

United States
Sanofi
Regeneron Pharmaceuticals

Completed

Evaluation of Dupilumab's Effects on Airway Inflammation in Patients With Asthma (EXPEDITION)

Asthma

Denmark, United States, Canada, Germany, Sweden, United Kingdom
AstraZeneca
Amgen

Completed

Study to Evaluate Tezepelumab on Airway Inflammation in Adults With Uncontrolled Asthma (CASCADE) (CASCADE)

Respiratory Tract Diseases | Immune System Diseases | Lung Diseases | Hypersensitivity | Hypersensitivity, Immediate | Bronchial Diseases | Lung Diseases, Obstructive | Asthma | Respiratory Hypersensitivity

United States, Canada, Denmark, United Kingdom, Germany
Organon and Co

Completed

Asthma Study Comparing Anti-Inflammatory Effects of 3 Doses of Mometasone Furoate/Formoterol Fumarate and Medium Dose Mometasone Furoate (Study P05122 AM1)(COMPLETED)

Asthma | Airway Inflammation
T-Balance Therapeutics GmbH

Completed

Effects of Tregalizumab on Allergen-induced Airway Responses and Airway Inflammation in Asthmatic Patients (Tregulaire)

Allergic Asthma | Allergy to House Dust Mite

Germany
Imperial College London

Completed

The Natural History of Small Airways Physiology in Diseased and Healthy States

Asthma | Cystic Fibrosis | Interstitial Lung Disease | COPD | Patients Requiring Lung Transplant

United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

An Imaging Study Using PET/CT to Characterize the Effect of Intravenous Reslizumab on Airway Inflammation (DEAR)

Asthma

United States
Canadian Research & Education in Arthritis
AbbVie

Completed

Osteoarthritis of the Knee, Inflammation, and the Effect of Adalimumab (OKINADA) (OKINADA)

Osteoarthritis, Knee

Canada
University Hospital Inselspital, Berne

Enrolling by invitation

Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants

Healthy Volunteers

Switzerland

Search clinical trials for: Airway inflammation

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