Search clinical trials for: COMT gene polymorphism

Total 267060 results

University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Recruiting

Correlation Between COMT Val158Met Polymorphism and Dopaminergic Transporter Density (DAT) in Obese Women

Obesity

Brazil
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Pharmacogenetics of Cannabinoid Response

COMT Gene Polymorphism

United States
Assistance Publique - Hôpitaux de Paris

Completed

Compensation Mechanisms in Parkinson's Disease (DATACOMT)

Parkinson Disease

France
University of California, San Diego

Completed

Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.

Schizophrenia

United States
Kunming Medical University
National Natural Science Foundation of China

Completed

5-HTR2A, DRD2,and COMT Genes Polymorphisms and Olanzapine Plasma Concentration in Treatment of Early-onset Schizophrenia

Early-onset Schizophrenia

China
Sheffield Hallam University

Unknown

Mod of Cognitive Flexibility by tDCS, Tyrosine Polymorphisms in the COMT Gene

Modulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT Gene

United Kingdom
Parc de Salut Mar
National Institute on Drug Abuse (NIDA)

Completed

-Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms

Metabolism | Interaction

Spain
University of Sao Paulo

Unknown

Genetic Association Study Between Single Nucleotide Polymorphisms (SNPs) and Cognitive Performance in Young Bipolar Type I Patients: LICAVALGENE (Licavalgene)

Bipolar

Brazil
East Tallinn Central Hospital

Unknown

MOR and COMT SNP Polymorphism and Pain

Pain Relief

Estonia
Austin Health

Completed

Catecholamine-O-Methyl-Transferase(COMT)-Polymorphism in Cardiac Surgery

Cardiac Surgery

Australia
Helwan University

Not yet recruiting

Palbociclib in Metastatic Breast Cancer: Gene Polymorphism-based Study in Egyptian Patients. (Palbociclib)

Metastatic Breast Cancer | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Hormone-receptor-positive Breast Cancer
Mahidol University

Not yet recruiting

The Efficacy of Pedometer-motivated Physical Activity for the Management of Patients With MASLD.

BMI | Metabolic Syndrome | Insulin Resistance | NAFLD | Genetic Polymorphism | Cardiovascular Disease (CVD) | MASLD | Daily Step Count
Augusto Vaglio

Recruiting

GWAS and EWAS in Patients With Erdheim-Chester Disease

Erdheim-Chester Disease

France, Italy, Spain
Lebanese University
Haykel Hospital

Recruiting

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA (PTST_PALBEVA)

Cancer | Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lung Cancer | Chemotherapy | Solid Tumor | Immunotherapy | Targeted Therapy | Precision Therapy

Lebanon
Karolinska Institutet

Recruiting

COronary Microcirculation and Troponin Elevation in Septic Shock (COMTESS)

Sepsis | Myocardial Injury | Endothelial Dysfunction | Coronary Microvascular Dysfunction

Sweden
University of Évora
Universidade Nova de Lisboa; Comprehensive Health Research Centre; Unidade Local... and other collaborators

Recruiting

Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome (VitDTracking)

Vitamin D Deficiency | Pregnancy

Portugal
University of Virginia
American Heart Association

Not yet recruiting

Implementation of Onsite Rapid CYP2C19 Assay for Genotype Guided Dual Antiplatelet Therapy After Acute Ischemic Stroke (ORCA-AIS)

Ischemic Stroke | CYP2C19 Polymorphism
Zunyi Medical College

Recruiting

CYP2C19 Genotype-Guided P2Y12 Receptor Inhibitor Selection After Complex Percutaneous Coronary Intervention

ACS - Acute Coronary Syndrome | CYP2C19 Polymorphism

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Effect of Mutations in T2DM Susceptibility Genes on the Expression of Susceptibility Genes in Patients With T2DM and Controls

Type 2 Diabetes Mellitus | Genetic Mutations | Gene Polymorphisms | Susceptibility, Genetic

China
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Association of Gene Polymorphism With Susceptibility to T2DM and the Therapeutic Responses to Exenatide in Chinese Patients With T2DM

Type 2 Diabetes Mellitus | Susceptibility, Genetic

China
Centre Hospitalier Universitaire de Besancon
University of Franche-Comté

Recruiting

Impact of Perceptive, Executive and Emotional Factors on Decision-making of Pedestrian Face to Autonomous Vehicles. (VASIS)

Decision-making

France
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors (NETTUNO)

Postoperative Complications | Surgical Procedure, Unspecified | Hyperlactatemia | Abdomen Disease

Italy
Novosibirsk Scientific Research Institute for Circulatory...

Recruiting

The Effect of Polymorphism of the GUCY1A3 rs7692387 Gene on Cardiovascular Events After Coronary Artery Bypass Grafting.

to Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass Grafting

Russian Federation
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
October 6 University
University of Florida; Beni-Suef University; National Heart Institute, Egypt

Recruiting

Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients

Heart Failure | Genetic Polymorphisms

United States
Marmara University

Not yet recruiting

Single Gene Polymorphisms Associated With Molar-Incisor Hypomineralization

Molar-Incisor Hypomineralization
The Republican Research and Practical Center for...
Belarusian State Medical University

Recruiting

To Develop an Algorithm for Predicting the Unfavorable Course of Sepsis in Children Based on a Comprehensive Assessment of Immunological, Biochemical and Molecular Genetic Markers

Sepsis

Belarus
LI YAN

Not yet recruiting

Study on the Association of GSTP1 and Other Gene Polymorphisms With Platinum-induced Myelosuppression

Non-small Cell Lung Cancer
Affiliated Hospital of Nantong University

Not yet recruiting

CYP1A2, ABCB1, CYP2C9 and Plasma Concentration of Agomelatine in Adult Patients With Depression

Depression | Polymerase Chain Reaction | Polymorphism, Genetic | CYP1A2 Polymorphism | Plasma Concentration | CYP2C9 Polymorphism
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Influence of Air Pollution on SPondyloarthritis Flare-ups and Resistance to Treatment (SPAIR)

Spondyloarthritis, Axial

France
Lebanese University
Haykel Hospital

Recruiting

Exploring Cancer-Associated Thromboembolism Prognosis Biomarkers and Polymorphisms (CAT_PB)

Cardiovascular Diseases | Immune System Diseases | Cancer | Breast Cancer | Hepatocellular Carcinoma | Lung Cancer | Chemotherapy | Solid Tumor | Prostate Cancer | Thromboembolism | Colon Cancer | Immunotherapy | Inflammatory Diseases

Lebanon
Nova Scotia Health Authority
Dalhousie University

Recruiting

Pictou County PEP: A 6-Month, Home-Based, Personal Empowerment Program for Adults With a Chronic Medical Condition Living in Pictou County

Chronic Condition

Canada
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Crizotinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-Small Cell Lung Cancer

United States
Sohag University

Recruiting

Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases in Sohag Hospital University.

Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases

Egypt
Sohag University

Recruiting

SIRT1(rs7069102 ) Gene Polymorphism in Chronic Obstructive Pulmonary Disease at Egyptian Patients

Genotyping of SIRT1in Chronic Obstructive Pulmonary Disease

Egypt
Laboratoires Innothera
Floralis

Recruiting

Long-Term Post Thrombotic Syndrome Assessment (CELEST Long Term). (CELEST-LT)

Post Thrombotic Syndrome

France
Han Xu, M.D., Ph.D., FAPCR, Sponsor-Investigator...

Not yet recruiting

Pharmacogenomics IND EXEMPT SNP Clinical Study - Alectinib and Single Nucleotide Polymorphisms (Drugs-SNPs)

Non-small Cell Lung Cancer

United States
Labrha
Statitec

Recruiting

Safety of Use and Efficacy of Pandora for Patients Suffering From Gonarthrosis (PANDORA2) (PANDORA2)

Knee Osteoarthritis

France, Monaco
Aptarion Biotech AG

Recruiting

Safety and Efficacy of AON-D21 in Severe Community-Acquired Pneumonia.

Community-acquired Pneumonia

United Kingdom, Germany, France
St. Antonius Hospital

Recruiting

POPular GUILTY PILOT: Genotype-guided Clopidogrel Monotherapy (POPular GUILTY)

Acute Coronary Syndrome | CYP2C19 Polymorphism

Netherlands
Yi Han
Qianfoshan Hospital

Recruiting

Study on the Correlation Between NAT2(N-acetyltransferase2) Gene Polymorphism and CrCl(Creatine Clreance) and the Efficacy and Safety of Levosimendan in Patients With Severe Heart Failure

Heart Failure | Efficacy | Safety | Levosimendan

China
Sohag University

Recruiting

Brain-derived Neurotrophic Factor (BDNF) Single Nucleotide Gene Polymorphism and Nerve Growth Factor as Risk Factors That Increase Severity of Allergic Rhinitis

Allergic Rhinitis

Egypt
The Republican Research and Practical Center for...
Belarusian State Medical University

Recruiting

Algorithm for Predicting the Unfavorable Course of Sepsis in Children

Sepsis

Belarus
Versantis AG

Recruiting

Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)™

Acute-On-Chronic Liver Failure | Ascites

Germany, Spain, Belgium, United States, France
Hospital Mutua de Terrassa

Recruiting

Mesenteric Bacterial Translocation in Evolved Crohn's Disease (MESENCROHN)

Crohn Disease

Spain
Kaohsiung Medical University Chung-Ho Memorial...
Ministry of Science and Technology, Taiwan

Recruiting

Effect of Gene Polymorphism on Cognitive Function

Cognitive Function | Polymorphosis

Taiwan
Ain Shams University

Recruiting

Effect of Renin Angiotensin Aldosterone System Genetic Polymorphism on the Pharmacological Effect of Mineralocorticoid Receptor Antagonists in Patients With Myocardial Infarction

Myocardial Infarction

Egypt
Sohag University

Recruiting

Polymorphism of Janus Kinase 1 and 2 (JAK 1&2) in Patients With Alopecia Areata

Alopecia Areata

Egypt
China Medical University Hospital

Recruiting

The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis

Allergic Conjunctivitis

Taiwan
IRCCS Burlo Garofolo

Recruiting

Genetic Polymorphisms in Drug Induced Neuropathy in Children With ALL

Acute Lymphocytic Leukemia

Italy

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