Search clinical trials for: CRx-197

Total 233 results

Zalicus

Completed

A Single-Center Exploratory Study to Assess the Activity of CRx-197-002 in Plaque Psoriasis (197-002)

Plaque Psoriasis

Germany
Zalicus

Completed

A Phase I Study to Assess the Safety and Tolerability of Topical CRx-197 Formulations in Healthy Volunteers

Atopic Dermatitis

Germany
HeNan Sincere Biotech Co., Ltd

Recruiting

A Study of CL-197 Capsules in Healthy Participants

HIV-1

China
Sonoma Orthopedic Products, Inc.

Terminated

Post Treatment Comparison Intramedullary Nail vs. Nonoperative Treatment

Fracture of Clavicle

United States
University of Chicago
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

CommunityRx-Hunger (CRx-H)

Food Insecurity

United States
Daiichi Sankyo, Inc.
ICON Clinical Research; ArQule, Inc. (a wholly owned subsidiary of Merck Sharp...

Completed

Determination of the Relative Bioavailability of ARQ 197 Tablet Formulation With Capsule C Formulation as a Reference in Subjects With Advanced Solid Tumors

Solid Tumors

United States
National Cancer Institute (NCI)

Terminated

Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma

Epithelioid Mesothelioma | Sarcomatoid Mesothelioma | Stage IV Pleural Mesothelioma | Recurrent Malignant Mesothelioma | Stage II Pleural Mesothelioma | Stage III Pleural Mesothelioma

United States
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Bioequivalence Study of ARQ 197 Amorphous and Crystalline Polymorphs A and B in Normal Healthy Volunteers

Healthy

United States
National Cancer Institute (NCI)

Completed

Tivantinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Childhood Solid Neoplasm

United States, Canada
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

A Phase 1 Study of ARQ 197 in Adult Patients With Advanced Solid Tumors (ARQ 197)

Cancer, Advanced Solid Tumors

United Kingdom
National Cancer Institute (NCI)

Completed

Tivantinib in Treating Patients With Recurrent or Metastatic Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma

United States
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Phase 2 Study in Patients With MiT Tumors

Renal Cell Carcinoma (RCC) | Alveolar Soft Part Sarcoma (ASPS) | Clear Cell Sarcoma (CCS)

United States, Canada, United Kingdom
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

ARQ 197 in Subjects With Metastatic Solid Tumors

Cancer | Tumor

United States
Daiichi Sankyo, Inc.

Terminated

ARQ 197 for Participants With Relapsed or Refractory Germ Cell Tumors

Non-CNS Germ Cell Tumors (Seminomas and Nonseminomas)

United States, France, United Kingdom
Kyowa Kirin Co., Ltd.

Completed

Study of ARQ 197 Monotherapy (ARQ 197-004)

Gastric Cancer

Japan, Korea, Republic of
National Cancer Institute (NCI)

Completed

Tivantinib in Treating Patients With Metastatic Prostate Cancer

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | Stage IV Prostate Cancer | Hormone-Resistant Prostate Cancer

United States
University of Chicago
National Institute on Aging (NIA)

Enrolling by invitation

CommunityRx-Dementia (CRx-D)

Health Related Social Needs (HRSN)

United States
Kyowa Kirin Co., Ltd.

Completed

Study of ARQ 197 in Hepatocellular Carcinoma (HCC)

Advanced Hepatocellular Carcinoma

Japan
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Safety Study of ARQ 197 in Cirrhotic Patients With Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma | Cirrhosis

Spain, United States, Italy
Daiichi Sankyo, Inc.
Medpace, Inc.

Completed

Effect of Tivantinib on the QTC Interval in Cancer Subjects

Solid Tumors

United States
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

Trial of ARQ 197 in Patients With Unresectable Hepatocellular Carcinoma (HCC) Who Have Failed One Prior Systemic Therapy

Unresectable Hepatocellular Carcinoma

Belgium, Italy, United States, Germany, Canada
Ann & Robert H Lurie Children's Hospital of Chicago
Patient-Centered Outcomes Research Institute; University of Chicago; Missing...

Recruiting

The Missing Pieces Trial: A Comparison of Two Interventions to Support Parents After Their Child's Unexpected or Traumatic Death

Bereavement

United States
Zambon SpA

Completed

A Study to Evaluate Pharmacokinetics, Safety and Tolerability of Single and Multiple Intravenous Doses of N-acetylcysteine (NAC) in Chinese Healthy Volunteers

Respiratory Tract Disorders

China
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

A Study of ARQ 197 in Healthy Volunteers to Assess the Pharmacokinetic (PK) Profile in Extensive and Poor Metabolizers as Defined by Cytochrome P450 2C19 (CYP 2C19) Genotype

Healthy

United States
Zalicus

Completed

Multicenter Study to Evaluate CRx-102 vs. Each of Its Components to Treat Active Rheumatoid Arthritis (MARS-1)

Rheumatoid Arthritis

United States, Poland, Argentina, Romania, Serbia, Canada, Estonia, Russian Federation, Lithuania, South Africa, Hungary, Mexico
National Cancer Institute (NCI)

Completed

Tivantinib in Treating Patients With Relapsed, or Relapsed and Refractory Multiple Myeloma

Refractory Multiple Myeloma

United States
Memorial Sloan Kettering Cancer Center
Gateway for Cancer Research

Recruiting

The Effect of Acupuncture on Nerve Pain Caused by Taxane (Chemotherapy) Treatment

Breast Cancer | Taxane-Induced Peripheral Neuropathy

United States
Ruijin Hospital

Recruiting

Secondary Infusion of Relma-cel Injection for Relapsed or Refractory B-cell Lymphoma

Relapsed or Refractory B-cell Lymphoma

China
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

CommunityRx-Cardiovascular Disease (CRx-CVD)

Cardiovascular Diseases | Self Efficacy

United States
National Institute of Allergy and Infectious Diseases...

Completed

9-valent CRM 197 Pneumococcal

Pneumococcal Infection

United States
Ono Pharmaceutical Co. Ltd

Completed

Controlled Study of ONO-8025 (KRP-197) in Patients With Overactive Bladder in Japan

Overactive Bladder
Zalicus

Terminated

CRx-102 Osteoarthritis Multicenter Evaluation Trial (COMET-1)

Knee Osteoarthritis

United States, Canada
QuiO
SHL Medical; MidMichigan Health

Unknown

Chronicare for Type 2 Diabetes (Chronicare-T2D) (CRX-T2D)

Type 2 Diabetes

United States
Ono Pharmaceutical Co. Ltd

Completed

Controlled Study of ONO-8025 (KRP-197) in Patients With Overactive Bladder in Japan

Overactive Bladder
IRCCS Policlinico S. Matteo

Unknown

Lactoferrin for the Treatment of Symptomatic Uncomplicated Diverticular Disease (SUDDENLY)

Diverticular Disease | Symptomatic Uncomplicated Diverticular Disease

Italy
GlaxoSmithKline

Completed

Meningococcal Quadrivalent CRM-197 Conjugate Vaccine Infant Study

Meningococcal Disease | Infections, Meningococcal

United States
National Cancer Institute (NCI)

Completed

Pazopanib and ARQ 197 for Advanced Solid Tumors

Solid Tumor

United States
St George's, University of London
Pfizer; MU-JHU CARE

Active, not recruiting

Clinical Trial Investigating the Safety and Immunogenicity of GBS6 in Pregnant Women With and Without HIV (PREPARE) (PREPARE)

Group B Streptococcal Infection

Uganda
Kyowa Kirin Co., Ltd.

Completed

ARQ 197 Plus Erlotinib in Patient With Locally Advanced or Metastatic EGFR Mutation-positive Non-small-cell Lung Cancer

Non-small-cell Lung Cancer

Japan
Ono Pharmaceutical Co. Ltd
Kyorin Pharmaceutical Co.,Ltd

Completed

Long-term Safety and Efficacy of Imidafenacin in Patients With Overactive Bladder

Overactive Bladder

Japan
Zalicus

Completed

Study of CRx-401 on Glucose Levels in Subjects With Type II Diabetes

Type 2 Diabetes

Canada
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

A Phase 1 Study of ARQ 197 in Adult Patients With Advanced Solid Tumors

Cancer

United States
GlaxoSmithKline

Completed

Meningococcal Quadrivalent CRM-197 Conjugate Vaccine Pregnancy Registry

Pregnancy | Meningococcal Disease | Infections, Meningococcal

United States
Armando Santoro, MD

Completed

Study of the Combination of Tivantinib Plus Pemetrexed and Carboplatin

Nonsquamous Nonsmall Cell Neoplasm of Lung | Malignant Pleural Mesothelioma

Italy
Zalicus

Completed

Phase I Study of Topical CRx-191 in Normal Healthy Volunteers

Healthy

Germany
Zalicus
Bioskin GmbH

Completed

Study of CRx-191 to Assess Activity in Plaque Psoriasis

Plaque Psoriasis

Germany
Kyowa Kirin Co., Ltd.

Completed

A Study of ARQ 197 in Combination With Erlotinib

Advanced/Recurrent Non-small-cell Lung Cancer

Japan
Kyowa Kirin Co., Ltd.

Completed

A Study of ARQ 197 in Combination With Erlotinib

Non-small-cell Lung Cancer

Japan
The Immunobiological Technology Institute (Bio-Manguinhos)...

Unknown

Conjugate Vaccine Against Meningococcus C a Brazilian Project

Serogroup C Meningococcal Meningitis

Brazil
National Cancer Institute (NCI)

Completed

Tivantinib and Temsirolimus in Treating Patients With Solid Tumors That is Metastatic or Cannot be Removed by Surgery

Adult Solid Neoplasm

United States

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