Search clinical trials for: Ceftaroline

Total 54 results

Clinical Research Centre, Malaysia

Not yet recruiting

Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia (EVOS)

Staphylococcus Aureus Bacteremia

Malaysia
UMC Utrecht
National University Hospital, Singapore; Berry Consultants; University of Pittsburgh... and other collaborators

Recruiting

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia (REMAP-CAP)

Community-acquired Pneumonia, Influenza, COVID-19

United Kingdom, United States, Canada, Australia, Netherlands, Croatia, Germany, Belgium, New Zealand, Ireland, Spain, Japan, Hungary, Colombia, India, Nepal, Pakistan, Portugal, Romania, Saudi Arabia
Medical University of Vienna

Recruiting

Multiple-dose Pharmacokinetics of Ceftaroline During Continuous and Intermittent Renal Replacement Therapy in Patients Requiring Renal Replacement Therapy

Infection During Renal Replacement Therapy

Austria
Pfizer

Completed

Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries

Community Acquired Pneumonia | Complicated Skin and Soft Tissue Infection

Spain, Brazil, Colombia, France, Greece, Italy, Russian Federation
Centre Hospitalier Universitaire Dijon

Completed

Penetration of Ceftaroline Into Cerebrospinal Fluid(CSF) (Ceftaroline)

Meningitis | Ventriculitis

France
West Virginia University

Enrolling by invitation

Comparing Oral Versus Parenteral Antimicrobial Therapy (COPAT)

Skin and Soft Tissue Infection | Gastrointestinal Infection | Pulmonary Infection | Bone and Joint Infection | Endovascular Infection | Genitourinary Infection

United States
Vinay Badhwar

Enrolling by invitation

Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) (OPTIMAL)

Endocarditis

United States
Children's Hospital Medical Center, Cincinnati

Active, not recruiting

Pharmacokinetic and Pharmacodynamic Analysis of Ceftaroline in Children and Adolescents With Cystic Fibrosis

Cystic Fibrosis

United States
Henry Ford Health System

Terminated

Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients (STOP-NT)

Bacteremia | Endocarditis | Acute Bacterial Skin and Skin Structure Infections | Health Care Associated Pneumonia | Osteomyelitis/Septic Arthritis

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery (COLONPREP)

Colon Cancer

France
Baylor College of Medicine
Allergan

Completed

Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children

Osteomyelitis | Bone Infection | Hematogenously Acquired Staphylococcus Aureus Osteomyelitis

United States
University of Maryland, Baltimore

Completed

Ceftaroline Pharmacokinetics in Continuous Renal Replacement Therapy

Critically Ill | Infection During Renal Replacement Therapy

United States
Hospices Civils de Lyon

Completed

Evaluation of the Tolerance of Ceftaroline and Ceftobiprole in the Management of BJI / PJI

Antibiotic Reaction | Bone and Joint Infection

France
Fundación Pública Andaluza para la gestión de la...

Unknown

Study to Optimize the Use of New Antibiotics (NEW_SAFE)

Bacterial Infections | Fungal Infection

Spain
Carol Johnston

Completed

The Effect of Vinegar Consumption on Visceral Fat and Blood Glucose Concentration (VIVO)

Insulin Resistance | Visceral Obesity | Tooth Erosion
Arrevus Inc.

Terminated

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

Prosthetic Joint Infections of Hip | Prosthetic Joint Infections of Knee | Infected Spacers

United States
Poitiers University Hospital

Completed

Population Pharmacokinetic (PK) Study of Zinforo (Ceftaroline) in Critical Care Patients With Early-onset Pneumonia and Normal or Augmented Renal Clearance (CEFTAREA)

Pneumonia

France
Basim Asmar
Forest Laboratories

Unknown

Ceftaroline Diffusion Into Cerebrospinal Fluid of Children

Ventriculoperitoneal Shunt | Cerebrospinal Fluid Shunts

United States
Pfizer
PRA Health Sciences

Terminated

Safety, Tolerability and Efficacy of Ceftaroline in Paediatrics With Late-Onset Sepsis

Late-onset Sepsis

United States, Hungary
Sharp HealthCare

Completed

IL-10 Stratifying Tool for Towards Antibiotic Selection for MRSaB

Bacteremia

United States
Pfizer
Forest Laboratories

Terminated

Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections.

Complicated Skin and Soft Tissue Infection

Croatia, Bulgaria, Italy, Turkey, Romania, Argentina, Brazil, Chile, Israel, Poland, South Africa, Greece, Spain
Pfizer
Forest Laboratories

Completed

A Study to Evaluate the Efficacy and Safety of Intravenous Ceftaroline Versus Intravenous Ceftriaxone in the Treatment of Adult Hospitalised Patients With Community-Acquired Bacterial Pneumonia in Asia

Community-Acquired Bacterial Pneumonia | Lung Infection of Individual Not Recently Hospitalized

Korea, Republic of, Vietnam, China, Taiwan, India
Pfizer
Forest Laboratories

Completed

Evaluation of Ceftaroline Fosamil Versus Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections

Complicated Skin and Soft Tissue Infection

United States, Croatia, Australia, Bulgaria, Italy, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, South Africa, Spain, Turkey, Philippines, China, Romania, Argentina, Brazil, Chile, Czechia, Israel, Greece, Taiwan, Ukr... and more
Pfizer

Completed

A 2-part Study to Assess Local Tolerability, Safety and Pharmacokinetics of Ceftaroline in Healthy Subjects

Healthy

United Kingdom
Pfizer

Completed

A Study to Assess the Pharmacokinetics of Ceftaroline in End Stage Renal Disease Patients and Matched Healthy Subjects

Renal Disease

United Kingdom
Pfizer

Completed

A Study to Investigate the Effect of Administration of Ceftazidime-avibactam (CAZ-AVI) and Ceftaroline Fosamil -Avibactam (CXL) on the Intestinal Flora of Healthy Volunteers

Pharmacokinetics | Safety | Open Label | CAZ-AVI | CXL | Effect on Intestinal Flora

Sweden
Pfizer
Forest Laboratories

Completed

Ceftaroline China Pharmacokinetics Study (CeftarolineChi)

Healthy

China
Pfizer

Completed

A Study to Assess Safety, Tolerability and Pharmacokinetics of Ceftaroline in Healthy Subjects

Healthy Volunteers

United Kingdom
Pfizer

Completed

A Single-centre, Randomised, Double-blind, Placebo-controlled, Four Way Crossover Phase I Study to Investigate the Effect on QT/QTc Interval of Ceftazidime NXL104 or Ceftaroline Fosamil NXL104, Compared With Placebo, Using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male Volunteers

Healthy Male Volunteers

United States
Forest Laboratories

Completed

Pharmacokinetic Study of Ceftaroline Fosamil/Avibactam in Adults With Augmented Renal Clearance

Systemic Inflammatory Response Syndrome (SIRS) | Augmented Renal Clearance (ARC)

United States, Australia
Forest Laboratories

Completed

Efficacy and Safety of Ceftaroline Versus Linezolid in Subjects With Complicated Skin and Skin Structure Infections

Bacterial Infection

United States
Forest Laboratories

Completed

Pharmacokinetics of Ceftaroline in Subjects 12 to 17 Years of Age

Infection

United States
Forest Laboratories

Completed

Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia (CAP)

Bacterial Pneumonia

United States, Russian Federation, Bulgaria, Germany, Poland, Romania, Ukraine, Argentina, Austria, Brazil, Estonia, France, Georgia, Hungary, India, Lithuania, Malaysia, Serbia, Slovakia, South Africa, Spain, Switzerland, Thailand
Forest Laboratories

Completed

Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections (cSSSI)

Bacterial Infections

Argentina, Chile, Mexico, Russian Federation, United States, Poland, Germany, Brazil, Peru, Romania, Ukraine
Forest Laboratories

Completed

Comparative Study of Ceftaroline vs. Ceftriaxone in Adults With Community-Acquired Pneumonia (CAP)

Bacterial Pneumonia

United States, Argentina, Austria, Bulgaria, Chile, Germany, Hungary, India, Latvia, Mexico, Peru, Poland, Romania, Russian Federation, Ukraine
Forest Laboratories

Completed

Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infections

Bacterial Infections

United States, Chile, Latvia, Poland, Russian Federation, Argentina, Mexico, Austria, Brazil, Germany, Ukraine, United Kingdom
Wayne State University
Forest Laboratories; Henry Ford Hospital; St. John Providence Health System; Detroit...

Completed

Clinical and Economic Outcomes of Ceftaroline Fosamil for ABSSSI Documented or at Risk of MRSA

Skin Diseases, Infectious | Staphylococcal Skin Infections

United States
Olayemi Osiyemi MD
Forest Laboratories

Unknown

Antibiotic Prophylaxis in Open Fractures

Open Fractures

United States
Gary E. Stein, Pharm.D.
Forest Laboratories

Completed

Pharmacodynamic of Ceftaroline and Levofloxacin Against Pathogens Associated With Community Acquired Bacterial Pneumonia

Pneumonia, Bacterial | Community-acquired

United States
Forest Laboratories
AstraZeneca

Completed

Evaluation of Ceftaroline Fosamil Versus a Comparator in Adult Subjects With Community-acquired Bacterial Pneumonia (CABP) With Risk for Methicillin-resistant Staphylococcus Aureus

Infections

Poland, Romania, Russian Federation, Ukraine, Georgia, Hungary, United States, Spain
University of Cincinnati
Forest Laboratories

Unknown

The Use of Ceftaroline as Surgical Prophylaxis in Surgery With Risk of MRSA Infection (PREVTAROLINE)

Surgical Site Infection

United States
Forest Laboratories

Completed

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Community Acquired Pneumonia (CABP)

Infections | Pneumonia

United States, Ukraine, Argentina, Georgia
Forest Laboratories
AstraZeneca

Completed

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Complicated Skin Infections

Infections, Pediatrics

United States, Argentina, Chile, Georgia, Latvia, Lithuania, Poland, Romania, South Africa, Spain
Forest Laboratories
AstraZeneca

Completed

Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)

Infections | Community Acquired Pneumonia

Spain, United States, Argentina, Bulgaria, Georgia, Greece, Hungary, Poland, Ukraine
Orlando Health, Inc.
Forest Laboratories

Withdrawn

Ceftaroline in the Treatment of Bone and Joint Infections

Osteomyelitis | Joint Infections

United States
Forest Laboratories

Completed

Safety and Efficacy Study of Ceftaroline in Subjects With Staphylococcus Aureus Bacteremia or With Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia

Staphylococcus Aureus Bacteremia | Methicillin-resistant Staphylococcus Aureus (MRSA) Bacteremia

United States
Forest Laboratories

Completed

Study of Blood Levels of Ceftaroline Fosamil in Children Who Are Receiving Antibiotic Therapy in the Hospital

Infections

United States
Albany Medical College
Forest Laboratories; Albany College of Pharmacy and Health Sciences

Completed

Use of Ceftaroline in Hospitalized Patients With Community Acquired Pneumonia (CAP)

Community Acquired Bacterial Pneumonia

United States
Forest Laboratories

Completed

Comparative Study of Coadministered Ceftaroline Fosamil and NXL104 vs. Intravenous Doripenem in Adult Subjects With Complicated Urinary Tract Infections

Urinary Tract Infections

Russian Federation, Bulgaria, Poland, Germany, United States, Lebanon, Turkey
AstraZeneca

Completed

Multicenter Study of Antimicrobial Resistance of Gram-positive and Gram-negative Clinical Strains to Ceftaroline and Other Antimicrobials in Russia (CERBERUS)

Bacterial Skin Diseases

Russian Federation

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