Search clinical trials for: DPP4

Total 60 results

First Affiliated Hospital Xi'an Jiaotong University

Unknown

Therapies on Newly Diagnosed Type 2 Diabetes Patients With High Glucose Toxicity Which Protect Islet β Cell (TOND)

Type 2 Diabetes Mellitus

China
Brigham and Women's Hospital
Patient-Centered Outcomes Research Institute; Massachusetts General Hospital; University of Missouri-Columbia and other collaborators

Recruiting

BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes (BESTMED)

Diabetes Mellitus, Type 2

United States
Kaiser Permanente
Patient-Centered Outcomes Research Institute; Henry Ford Health System; HealthPartners... and other collaborators

Recruiting

Comparison of Type 2 Diabetes Pharmacotherapy Regimens (ON TARGET DM)

Cardiovascular Diseases | Type 2 Diabetes Mellitus

United States
Tel Aviv University
Zohar Landau; Shani Tsameret

Unknown

Influence of Dairy Protein Breakfast on Glycemia, Weight Loss and Clock Genes in T2D (Mdiet)

Type2 Diabetes | Healthy Obesity, Metabolically

Israel
The Royal Bournemouth Hospital
Merck Sharp & Dohme LLC

Completed

How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin. (MSD-GLP1)

Type 2 Diabetes Mellitus

United Kingdom
Rio de Janeiro State University

Completed

DPP4 Activity, Microvascular Reactivity and Inflammation (DPP4)

Overweight | Pre Diabetes | Diabetes Mellitus Type 2 Without Complication
University Hospital Muenster

Completed

Perioperative Sitagliptin Medication for Reduction of the Inflammatory Response Associated With Cardiopulmonary Bypass (SiCa-Flam)

Systemic Inflammatory Response Syndrome

Germany
Chinese PLA General Hospital

Completed

Prognostic Value of Plasma DPP4 Activity in ST-elevation Myocardial Infarction Patients

Coronary Angiography | Dipeptidyl Peptidase 4
University of Miami

Withdrawn

Effects of DPP4 Inhibition on COVID-19

Coronavirus Infection | Type 2 Diabetes

United States
National Health Research Institutes, Taiwan

Completed

A Multiple Ascending Dose Phase I Study of DBPR108 in Healthy Male Subjects

Diabetes Mellitus, Type 2

Taiwan
National Health Research Institutes, Taiwan

Completed

A Single-dose Phase 1 Study of DBPR108 in Healthy Male Subjects

Diabetes Mellitus, Type 2

Taiwan
University Medical Centre Ljubljana

Completed

Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss

Polycystic Ovary Syndrome | Body Weight
David D'Alessio, M.D.
Merck Sharp & Dohme LLC

Completed

DPP4 Inhibition & Beta Cell Function

Healthy

United States
University Malaysia Sarawak
Sarawak General Hospital

Completed

DPP4 Inhibitor on Glycemic Variability

Diabetes Mellitus, Type 2

Malaysia
Profil Institut für Stoffwechselforschung GmbH
Merck Sharp & Dohme LLC

Completed

Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients

Pharmacological Action

Germany
Vanderbilt University

Completed

Effect of DPP4 Inhibition on Vasoconstriction

Type 2 Diabetes Mellitus

United States
The Catholic University of Korea

Completed

DPP4 Inhibitor and Coronary Atherosclerosis in Patients Receiving Insulin Therapy

Diabetes Mellitus

Korea, Republic of
Mackay Memorial Hospital

Unknown

The Efficacy of Sodium-glucose Co-transporter 2 Inhibitor or Dipeptidyl Peptidase-4 Inhibitor in Type 2 Diabetes Patients With Premix Insulin

Type2 Diabetes

Taiwan
Phenomix
Forest Laboratories

Completed

Safety and Efficacy Study of Dutogliptin/PHX1149T to Treat Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States, Ukraine, Argentina, Malaysia, India, Romania, Thailand, Philippines, Peru
Seoul National University Bundang Hospital
LG Life Sciences

Unknown

Effects of DPP4 Inhibitor on Cisplatin Induced Acute Kidney Injury

Cancer | Cisplatin Adverse Reaction

Korea, Republic of
Phenomix

Terminated

Long-term Extension Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States, Argentina, Canada, Mexico, India
Phenomix
Forest Laboratories

Terminated

Study to Evaluate Safety and Efficacy of Dutogliptin in Type 2 Diabetes Mellitus Subjects With Moderate and Severe Renal Impairment

Type 2 Diabetes Mellitus | Renal Impairment

United States, Russian Federation, Ukraine
Phenomix
Forest Laboratories

Terminated

Safety and Efficacy Study of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

Type 2 Diabetes Mellitus

United States, Argentina, Chile, Czech Republic, India, Peru, Poland
Phenomix
Forest Laboratories

Terminated

Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

Type 2 Diabetes Mellitus

United States, Argentina, India, Peru, Poland, Czech Republic
Chiang Mai University

Completed

Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor

Diabetes Mellitus, Type 2 | Ischemic Heart Disease

Thailand
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM

Type 2 Diabetes Mellitus

China
University of Dundee

Completed

Study of Sulphonylurea Synergy With DPP4 Inhibitors (SSS)

Type 2 Diabetes

United Kingdom
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Effect of DPP4 Inhibition on Growth Hormone Secretion

Obesity

United States
Chung-Ang University

Unknown

The Effect of DPP4 Inhibitor on Vasclular Healing

Diabetes Mellitus, Type 2 | Acute Coronary Syndrome

Korea, Republic of
Phenomix
Forest Laboratories

Terminated

Long-term Study to Evaluate the Safety of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus | Type 2 Diabetes

United States, Malaysia, Peru, India, Argentina, Philippines, Romania, Ukraine
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study to Evaluate the Efficacy and Safety of DBPR108 100 mg in Type 2 Diabetes Mellitus Patients

Type 2 Diabetes Mellitus

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

DBPR108 Tablets in Type 2 Diabetes Mellitus Patients

Type 2 Diabetes Mellitus

China
University of Pennsylvania

Recruiting

Effects of Sitagliptin in Individuals With Genetically Decreased DPP4

Heart Failure | Type2 Diabetes | Genetics Disease

United States
Vanderbilt University

Completed

Effect of Chronic ACE and DPP4 Inhibition on Blood Pressure

Hypertension | Type 2 Diabetes Mellitus

United States
Chang Gung Memorial Hospital
National Taiwan University Hospital; Chiayi Christian Hospital; Tainan Sin-lau...

Recruiting

Pioglitazone and SGLT2 Inhibitors vs. DPP4 Inhibitors in Patients With Stroke

Stroke | Diabetes Mellitus

Taiwan
Royal Devon and Exeter NHS Foundation Trust
Novartis Pharmaceuticals; National Institute for Health Research, United Kingdom

Completed

The Vascular Effects of Vildagliptin in Insulin Resistant Individuals

Insulin Resistance | Microvascular Disease

United Kingdom
Sadat City University
Beni-Suef University

Completed

Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?

Diabete Type 2

Egypt
Kun-Ho Yoon
Takeda

Completed

The Practical Evidence of Antidiabetic Combination Therapy in Korea (PEAK)

Type 2 Diabetes Mellitus

Korea, Republic of
University Hospital, Gentofte, Copenhagen

Completed

Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion (Px-Meal)

Diabetes After Total Pancreatectomy

Denmark
Brigham and Women's Hospital
Johns Hopkins University; National Institute on Aging (NIA); Rutgers University

Active, not recruiting

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors

Diabetes

United States
University of Pisa

Unknown

SGLT-2 and DPP-4 Inhibition, Subclinical Inflammation of the Genito-urinary Tract and Risk of Infections. (UTI-flog)

Type 2 Diabetes | Urinary Tract Infections

Italy
MTI University
National Institute of Diabetes and Endocrinology, Egypt

Recruiting

The Effect of Metformin and DPP4 Inhibitors on Cognition and Cardiovascular Protection in Type 2 Diabetic Patients

Type 2 Diabetes Mellitus

Egypt
Tel Aviv University

Completed

Whey Protein on Posprandial Glucose, Insulin GLP-1, GIP and DPP4 in Type 2 Diabetes (WheyGLP-1)

Type 2 Diabetes Mellitus

Israel
AstraZeneca
Parexel

Completed

Phase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single Components

Healthy Volunteers (Intended Indication: Type 2 Diabetes Mellitus)

Germany
Assiut University

Unknown

Role of Endothelial Biomarkers in Patients With Coronary Artery Disease

Coronary Artery Disease | Diabetes Mellitus | Cytomegalovirus Infections
Royal Devon and Exeter NHS Foundation Trust
King's College London; Newcastle University; NHS Tayside; University of Dundee; University... and other collaborators

Completed

TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes. (TriMaster)

Type 2 Diabetes

United Kingdom
Emory University
Merck Sharp & Dohme LLC; University of Michigan; Temple University; Ohio University

Completed

Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes

Type 2 Diabetes

United States
Metabolic Research Unit

Enrolling by invitation

ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT

Type 2 Diabetes | Abdominal Obesity

Mexico
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Unknown

Intact Liver Innervation and Glucose and Glucagon-like Peptide-1 (GLP-1) Induced Insulin Secretion

Liver Transplantation

Denmark
Brigham and Women's Hospital

Completed

Safety and Efficacy of Saxagliptin for Glycemic Control in Non-Critically Ill Hospitalized Patient

Diabetes Mellitus

United States

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