Search clinical trials for: Fibrinolysis

Total 110 results

Supergene, LLC

Not yet recruiting

Non-immunogenic Recombinant Staphylokinase vs Placebo in Patients With Intermediate High-risk Pulmonary Embolism

Pulmonary Embolism

Russian Federation
Policlinico Hospital

Recruiting

Point of Care Evaluation of Fibrinolysis in Sepsis (POCEFIS)

Sepsis | Critical Illness | Fibrinolytic Defect

Italy
Assiut University

Not yet recruiting

Impact of Antenatal Steroids on Coagulation.

Corticosteroids Adverse Reaction
Brigham and Women's Hospital
Boston Scientific Corporation

Not yet recruiting

Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PE (SONIC-PE)

Pulmonary Embolism | Right Ventricular Dysfunction | Right Ventricular Failure
East and North Hertfordshire NHS Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust

Recruiting

An Investigator-initiated Linked Study to OCEANIC-AF

Atrial Fibrillation

United Kingdom
Konkuk University Medical Center
Asan Medical Center; Korea Health Industry Development Institute; Soon Chun Hyang...

Recruiting

Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery

Prostate Cancer | Hepatic Cancer | Spine Fusion | Arthritis Knee | Arthritis of Hip

Korea, Republic of
Konkuk University Medical Center
Samsung Medical Center; Asan Medical Center; Korea Health Industry Development... and other collaborators

Recruiting

Goal-directed vs. Empirical Tranexamic Acid Administrationin Cardiovascular Surgery

Heart Diseases | Vascular Diseases | Fibrinolysis; Hemorrhage | Transfusion Related Complication | Coagulation Disorder, Blood

Korea, Republic of
University Hospital, Geneva

Recruiting

Bleeding of Unknown Cause: a Swiss Case-control Study (SWISS-BUC)

Bleeding Disorder

Switzerland
ITEL Telecomunicazioni Srl
Advice Pharma Group srl

Not yet recruiting

Prospective Comparative Study for Patients With Biochemical Recurrence Prostate Cancer Detecting by 18F-JK-PSMA-7 (MIP7)

Prostate Cancer | Radiotherapy | Prostatectomy | 18F- Fluorocholine | PSMA PET | Tumor of Prostate
AO GENERIUM

Recruiting

Study of Efficacy and Safety of GNR-060 vs Metalyse in Patients With ST Elevation Myocardial Infarction

ST Elevation Myocardial Infarction

Russian Federation
South West Sydney Local Health District

Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure (VETtiPAT-ARF)

Acute Respiratory Failure | Hypercoagulability | Fibrinolysis Shutdown

Australia
Heart Center Leipzig - University Hospital

Recruiting

Catheter-interventional Treatment of Pulmonary Embolism (CATCH-PE)

Pulmonary Embolism

Germany
Assistance Publique - Hôpitaux de Paris
National Research Agency, France

Recruiting

Characterization of the microVAScular Dysfunction in Covid-19 ARDS (VASCOV)

ARDS, Human | COVID-19 Acute Respiratory Distress Syndrome

France
Boston Scientific Corporation
University Medical Center Mainz; National PERT Consortium, Inc.

Recruiting

Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism (HI-PEITHO)

Pulmonary Embolism

United States, France, United Kingdom, Ireland, Switzerland, Germany, Netherlands, Austria, Poland
West China Hospital

Not yet recruiting

Optimal Reperfusion Strategy for STEMI Patients With Anticipated PPCI Delay

ST Elevation Myocardial Infarction
Harbin Medical University
Tasly Pharmaceuticals, Inc.

Recruiting

Primary FIbrinolysis and Secondary STenting Versus immEdiate Stenting in ST-segment Elevation Myocardial Infarction (FISSTEMI)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Coronary Artery Disease | Coronary Disease | Arteriosclerosis | Arterial Occlusive Diseases | Acute Coronary Syndrome | Syndrome Heart Disease

China
Loyola University
Boston Scientific Corporation

Not yet recruiting

Fibrinolytic Deficit in Patients With Acute PE

Acute Pulmonary Embolism | Fibrinolytic Deficit

United States
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
University of Alberta
Canadian VIGOUR Centre

Recruiting

SONOthrombolysis in Patients With an ST-segment Elevation Myocardial Infarction With fibrinoLYSIS (SONOSTEMI-LYSIS) Trial (SONOSTEMILYSIS)

ST Elevation Myocardial Infarction

Canada
Radboud University Medical Center
UMC Utrecht; Erasmus Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Rare Bleeding Disorders in the Netherlands (RBIN)

Rare Bleeding Disorders

Netherlands
University of Southern California

Completed

Nattokinase Atherothrombotic Prevention Study (NAPS)

Prevention of Subclinical Atherosclerosis Progression | Prevention of Cognitive Decline

United States
University Hospital, Caen

Suspended

Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage. (FIVHeMA)

Subarachnoid Hemorrhage

France
IRCCS Policlinico S. Donato

Active, not recruiting

Identification of Predictors for the Evolution of COVID-19 Related Pneumonia by Transcriptomic and Seroproteomic (COVID_OMICS)

Covid19 | Interstitial Pneumonia

Italy
Ersta Diakoni
Karolinska Institutet

Completed

Bariatric Surgery on obesity-and Diabetes-associated Abnormalities of Hemostasis, Inflammation and Vascular Function. (FIBRINO)

Diabetes Complications | Surgery | Coagulation Disorder | Obesity Associated Disorder
Universitaire Ziekenhuizen KU Leuven

Completed

Coagulation and Fibrinolysis as Virulence Factors for Invasive Staphylococcus Aureus and Streptococcus Infections

Infective Endocarditis | Necrotizing Fasciitis

Belgium
Supergene, LLC

Completed

Massive Pulmonary Embolism: Trial of Non-immunogenic Recombinant Staphylokinase VS Alteplase FORPE

Massive Pulmonary Embolism

Russian Federation
University of Texas Southwestern Medical Center
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Thrombosis Outcomes in Pediatric Venous Thromboembolism (TOP)

Venous Thromboembolism

United States
Denver Health and Hospital Authority

Terminated

STAT-STatin and Aspirin in Trauma (STAT)

Wounds and Injuries | Venous Thromboembolism

United States
Thomas Jefferson University

Completed

The Effect of Tranexamic Acid on Blood Coagulation in Total Hip Arthroplasty Surgery

Total Hip Arthroplasty | Coagulation; Intravascular | Fibrinolysis; Hemorrhage | Tranexamic Acid | Rotational Thromboelastometry

United States
IRCCS Policlinico S. Donato

Completed

Hemostatic Profile of Post COVID-19/Long COVID-19 Patients (LCV)

COVID-19 | Post-acute COVID-19 Syndrome

Italy
Medical College of Wisconsin

Terminated

Coagulation and Fibrinolysis of Estradiol in Transwomen

Transgenderism | Clotting Disorder

United States
Hebei Medical University Third Hospital

Completed

Anti-fibrinolytic and Anti-inflammatory Effects of Local Infiltration of Tranexamic Acid in Patients With Calcaneal Fractures

Fibrinolysis | Fracture | Tranexamic Acid | Inflammatory

China
University Hospital, Lille
Ministry of Health, France; French Health Products Safety Agency

Terminated

Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Caesarean Delivery (TRACES)

Hemorrhage | Pregnancy Complications

France
Hospital for Special Surgery, New York

Completed

Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty

Total Knee Arthroplasty

United States
Boston Scientific Corporation
EKOS Corporation

Completed

Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy (SEATTLE II)

Pulmonary Embolism | Acute Pulmonary Embolism | Pulmonary Thromboembolism | Massive Pulmonary Embolism | Sub-massive Pulmonary Embolism

United States
University of Edinburgh
NHS Lothian; Chief Scientist Office of the Scottish Government

Completed

Gap Junction Potentiation of Endothelial Function With Rotigaptide

Heart Disease | Vascular Disease

United Kingdom
National University of Malaysia

Completed

Short Duration High Intensity Intrapleural Alteplase With Pulmozyme in Pleural Infection Management

Loculated Empyema

Malaysia
Jagiellonian University

Active, not recruiting

Ovarian Hyperstimulation and Fibrin Clot Properties.

Endometriosis | Infertility, Female | Fibrin Blood Clot

Poland
University of Valencia

Completed

Brain Aneurysms: Utility of Cisternal Urokinase Irrigation (BA&UK)

Subarachnoid Hemorrhage, Aneurysmal | Hydrocephalus | Vasospasm, Cerebral

Spain
Tulane University

Completed

Fibrinolysis Compared to Thoracoscopy for Pleural Infection

Pleural Diseases | Pleural Infection | Empyema | Parapneumonic Effusion

United States
Daiichi Sankyo Co., Ltd.

Completed

Safety of DS-1040b in Acute Ischemic Stroke Patients Treated With Thrombectomy

Acute Ischemic Stroke

Japan
University of Texas Southwestern Medical Center

Completed

Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery (TXA)

Blood Loss | Post Partum Hemorrhage | Fibrinolysis; Hemorrhage

United States
Supergene, LLC

Completed

Single Bolus Recombinant Nonimmunogenic Staphylokinase (Fortelyzin) and Bolus Infusion Alteplase in Patients With AIS

Ischemic Stroke

Russian Federation
University Medical Centre Ljubljana

Unknown

The Influence of Noradrenaline on Coagulation and Fibrinolysis in Severe Isolated Brain Injury

Brain Injuries, Traumatic | Coagulopathy | Coagulation Defect; Bleeding | Coagulation Defect; Acquired | Fibrinolytic Hemorrhage, Acquired
Diagnostica Stago R&D
Hôpital d'Instruction des armées Percy

Completed

Determination of Fibrin Activity in Plasma on STA-R® Prototype (FAST)

Blood Coagulation Disorders | Hemorrhagic Disorders | Trauma | Thrombotic Disorders

France
University of California, San Francisco
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Coagulation and Fibrinolysis in Pediatric Insulin Titration Trial (CAF-PINT) (CAF-PINT)

Heart Failure | Respiratory Failure

United States
University Hospital, Bordeaux
Bordeaux Association for Training and Research in Obstetric Gynecology; Association...

Completed

Haemostasis and Tranexamic Acid in Caesarean Delivery (BIO-TRAAP)

Hyperfibrinolysis | Postpartum Hemorrhage

France
Yale University

Withdrawn

The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.

Pleural Effusion | Cancer, Lung
Jagiellonian University

Completed

Fibrin Clot Properties and Blood Loss Following Coronary Artery By-pass Grafting

Coronary Artery Disease | Coronary Artery Bypass | Blood Loss, Postoperative | Internal Mammary-Coronary Artery Anastomosis | Fibrinolysis

Poland
Beth Israel Deaconess Medical Center

Completed

Fibrinolysis Compared to Thoracoscopy for Pleural Infection

Pleural Diseases | Pleural Infection

United States

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