Search clinical trials for: Fluconazole

Total 236 results

DICE Therapeutics, Inc., a wholly owned subsidiary...
Eli Lilly and Company

Not yet recruiting

A Study to Assess LY4100511 (DC-853) in Healthy Adult Participants

Healthy

United States
Weill Medical College of Cornell University
The Leona M. and Harry B. Helmsley Charitable Trust

Not yet recruiting

Testing the Role for Anti-fungal Therapy in Improving the Response to Medicine for Crohn's Disease

Inflammatory Bowel Diseases | Crohn's Disease

United States
Alexion Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults

Healthy

United Kingdom
FEMPHARMA Kft.

Recruiting

Zinc-containing Vaginal Gel and Oral Fluconazole for Vulvovaginal Candidiasis.

Vulvovaginal Candidiasis | Vaginal Yeast Infections

Hungary
Beijing Children's Hospital
Shandong University

Recruiting

Population Pharmacokinetics of Fluconazole in the Treatment of Neonatal Fungal Infectious Disease

Pharmacokinetics | Infection | Newborn | Fluconazole

China
National Cancer Institute (NCI)

Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid... and other conditions

United States, Puerto Rico
Peking Union Medical College Hospital
CSPC Ouyi Pharmaceutical Group Co., Ltd.

Not yet recruiting

Clinical Study of ABCD in the Treatment of Cryptococcal Meningitis

Cryptococcal Meningitis

China
St George's, University of London
King's College London; Statens Serum Institut

Not yet recruiting

The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility Study (LISA)

Bacterial Vaginosis | Candida Vaginal

United Kingdom
Basilea Pharmaceutica

Not yet recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis

Candidemia | Candidiasis, Invasive
Maastricht University Medical Center
Zuyderland Medical Centre

Recruiting

The Effect of Medical Grade Honey Formulation (L-Mesitran) Administration on Recurrent Vulvovaginal Candidiasis Symptoms

Candidiasis, Vulvovaginal | Recurrent Candidiasis of Vagina

Netherlands
University of Oklahoma

Recruiting

Endothelial Derived Hyperpolarization Factor and Vascular Control

Healthy

United States
Radboud University Medical Center

Recruiting

Pharmacokinetics of Fluconazole in Children (2-18 Years) (FOCUS)

Invasive Fungal Infections

Netherlands
Jiangsu HengRui Medicine Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of SHR8008 vs. Fluconazole in Subjects With Recurrent Vulvovaginal Candidiasis

Recurrent Vulvovaginal Candidiasis

China
Karolinska Institutet

Recruiting

A Clinical Trial for Chlorhexidine as Treatment for Vulvovaginal Candidiasis

Candidiasis, Vulvovaginal

Sweden
M.D. Anderson Cancer Center

Recruiting

Cabozantinib and Pamiparib for the Treatment of Advanced of Refractory Solid Tumors

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm

United States
Benha University

Recruiting

SD-OCT Guided Treatment of Fungal Chorioretinitis

Fungal Retinitis

United Arab Emirates
University of Manitoba
Manitoba Medical Service Foundation; Research Manitoba

Recruiting

Vulvovaginal Candidiasis in Canadian Females (THRIVE-yeast)

Candidiasis, Vulvovaginal

Canada
Maastricht University Medical Center

Not yet recruiting

Fluconazol Versus Medical Honey in the Treatment of Recurrent Vulvovaginal Candidiasis

Candidiasis, Vulvovaginal | Recurrent Candidiasis of Vagina
Hospices Civils de Lyon

Recruiting

Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Fluconazole in Hypercalcicuric Patients With Increased 1.25(OH) 2D Levels (FLUCOLITH)

Nephrolithiasis | Hypercalciuria | Nephrocalcinosis

France
Cidara Therapeutics Inc.

Recruiting

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation (ReSPECT)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis | Invasive Fungal Disease | Pneumocystis | Mold Infection | Prophylaxis of Invasive Fungal Infections | Aspergillus

United States, Germany, France, Belgium, Canada, Italy, Spain, United Kingdom, Turkey, Switzerland
Azienda Sanitaria-Universitaria Integrata di Udine

Recruiting

Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) (TANDEM)

Subarachnoid Hemorrhage | Therapeutic Drug Monitoring | Intracerebral Hemorrhage

Italy
Makerere University
Gilead Sciences; University of Minnesota

Recruiting

Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia (ACACIA)

Cryptococcal Meningitis

Uganda
Radboud University Medical Center

Not yet recruiting

The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery (REMEDI)

Coronary Artery Disease | Systemic Inflammatory Response Syndrome | Extracorporeal Circulation; Complications | Postoperative Shock

Netherlands
Bochud Pierre-Yves
Swiss National Science Foundation

Recruiting

PTX3-targeted Antifungal Prophylaxis (PTX3AML)

Acute Myeloid Leukemia | Candidiasis | Fungal Infection | Aspergillosis | Genetic Predisposition

Belgium, Switzerland, France
QuantumLeap Healthcare Collaborative

Recruiting

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer (I-SPY)

Breast Cancer | Breast Neoplasms | Breast Tumors | HER2-positive Breast Cancer | Angiosarcoma | Locally Advanced Breast Cancer | HER2-negative Breast Cancer | TNBC - Triple-Negative Breast Cancer | Hormone Receptor Positive Tumor | Hormone Receptor Negative Tumor | Early-stage Breast Cancer

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Addition of an Immunotherapy Drug, Tremelimumab, to the PARP Inhibition Drug, Olaparib, for Recurrent Ovarian, Fallopian Tube or Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Primary Peritoneal Carcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Malignant Ovarian Endometrioid Tumor | Ovarian High Grade Serous Adenocarcinoma | Platinum-Sensitive Ovarian Carcinoma | Fallopian Tube High Grade Serous Adenocarcinoma and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Uterine Corpus Leiomyosarcoma

United States
The Hospital for Sick Children
St. Justine's Hospital; University of Waterloo

Completed

Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants

Breast Feeding

Canada
Matthew Neal MD
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 ACUTE (ACTIV-4A)

Covid19

United States, Spain, Brazil, Italy
Sinno H.P. Simons
Radboud University Medical Center; ZonMw: The Netherlands Organisation for... and other collaborators

Completed

Population PK/PD of Off Label Drugs in Premature Neonates (DINO)

Premature Birth

Netherlands
CTI BioPharma
PPD

Completed

Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

Drug Interactions

United States
Hutchmed

Completed

HMPL-689 Drug Interaction Study With CYP3A Inhibitor/CYP2C9 Inhibitor/CYP3A Inducer/PPI

Relapsed or Refractory Lymphoma

United States
University of Pennsylvania
Children's Hospital of Philadelphia; Crohn's and Colitis Foundation

Completed

Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease (Holiday)

Crohn's Disease

United States
Pharmtechnology LLC
Altasciences Company Inc.

Completed

Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions

Bioequivalence

Canada
BeiGene

Completed

Interaction Study of Zanubrutinib With Moderate and Strong CYP3A Inhibitors in Participants With B-Cell Malignancies

B-cell Malignancies

Australia
Scynexis, Inc.

Suspended

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole (MARIO)

Candidemia | Candidiasis, Invasive

United States, Korea, Republic of, Greece, Canada, France, Belgium, Germany, Italy, Spain, South Africa, Bulgaria, Israel
Epizyme, Inc.

Completed

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Mantle Cell Lymphoma | Marginal Zone Lymphoma | Advanced Solid Tumor | Diffuse Large B Cell Lymphoma | Primary Mediastinal Lymphoma

United States
Scynexis, Inc.

Completed

Phase 3 Study of Oral Ibrexafungerp (SCY-078) Vs. Placebo in Subjects With Recurrent Vulvovaginal Candidiasis (VVC) (CANDLE)

Recurrent Vulvovaginal Candidiasis

United States
AstraZeneca

Completed

Study to Evaluate Efficacy and Safety of Benralizumab in Reducing Oral Corticosteroid Use in Adult Patients With Severe Asthma (PONENTE)

Asthma

United States, Canada, Denmark, France, Italy, Sweden, United Kingdom, Belgium, Taiwan, Brazil, Poland, Russian Federation, Spain, Germany, Argentina, Colombia, Mexico
Combined Military Hospital Abbottabad

Completed

Comparison of Efficacy of Single Oral Dose Fluconazole and Itraconazole in Patients With Pityriasis Versicolor

Tinea Versicolor

Pakistan
Services Institute of Medical Sciences, Pakistan

Completed

Efficacy of Prophylactic Fluconazole Therapy in Preterm and Very Low Birth Weight Neonates in Preventing Invasive Fungal Infection.

Invasive Candidiases

Pakistan
Cairo University

Enrolling by invitation

Blue Light Emitting Diode Therapy on Vulvovaginal Candidiasis

Recurrent Vulvovaginal Candidiasis

Egypt
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Fluconazole on Pharmacokinetics of SHR2554 in Healthy Subjects

Malignant Tumor

China
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Comparison of Fluconazole vs Voriconazole to Treat Fungal Infections for Blood and Marrow Transplants (BMT CTN 0101)

Lymphoma | Leukemia | Infection

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

Drug-drug Interaction Study Between Fluconazole and Famitinib in Healthy Subjects

Tumor

China
Jazz Pharmaceuticals

Completed

An Study to Evaluate the Effects of Fluconazole on the Pharmacokinetics (PK) of Sativex® in Healthy Subjects With Cannabis Experience.

Healthy Subjects

United States
Alexion Pharmaceuticals

Completed

Drug Interaction Study of ALXN2050 With Fluconazole and Rifampin in Healthy Adult Participants

Healthy

United States
ProFem GmbH
Montavit Ges.m.b.H.

Active, not recruiting

A Phase IIb/III Study of Prof-001 for the Treatment of Patients With Recurrent Vulvovaginal Candidiasis (RVVC)

Recurrent Vulvovaginal Candidiasis

Austria, Poland, Slovakia
Concert Pharmaceuticals

Completed

Study to Evaluate Multiple Doses of Fluconazole, a CYP3A4 and CYP2C9 Inhibitor, on the Pharmacokinetics of CTP-543 in Healthy Subjects

Health Volunteers

United States

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