Search clinical trials for: Hyperalgesia

Total 205 results

Cedars-Sinai Medical Center

Not yet recruiting

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

Dexmedetomidine | Adolescent Idiopathic Scoliosis | Remifentanil | Posterior Spinal Fusion | Multimodal Analgesia | Opioid Induced Hyperalgesia
University of Pittsburgh

Recruiting

Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks (OMEGA)

Analgesia | Pain, Procedural | Pain, Chronic | Facet Joint Pain

United States
University Hospital, Basel, Switzerland

Recruiting

Boosting Open-Label Placebo Effects in Acute Induced Pain in Healthy Adults (BOLPAP)

Acute Pain

Switzerland
Centre Hospitalier Annecy Genevois

Recruiting

Response Profiles to High-concentration Capsaicin Desensitization in Patients With Peripheral Neuropathic Pain With or Without Allodynia: a Regional Multicenter Prospective Cohort (CAPSICAURA)

Peripheral Neuropathic Pain

France
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

Chronic Pain | Opioid-Related Disorders | Opioid Use Disorder | Opioid Dependence | Chronic Pancreatitis | Hyperalgesia | Chronic Pain Syndrome | ERCP | Pancreatic Surgery | Chronic Abdominal Pain

United States
Wake Forest University Health Sciences
HonorHealth Research Institute

Recruiting

Internet-delivered Management of Chemotherapy-Induced Peripheral Neuropathy (CIPN)

CIPN - Chemotherapy-Induced Peripheral Neuropathy

United States
Universiteit Antwerpen
University Hospital, Antwerp; Fund for Scientific Research, Flanders, Belgium

Recruiting

Identifying Biomarkers for Chronic Pain After Breast Cancer Treatment. (sCANsens)

Chronic Pain | Neoplasm, Breast | Carcinoma Breast

Belgium
University of Crete
University Hospital of Crete

Recruiting

Electroacupuncture Pain Treatment, Mechanical Hyperalgesia, Quality of Life & Expression of Mu+ B Cells in Fibromyalgia

Fibromyalgia | Hyperalgesia | Acupuncture | Electroacupuncture

Greece
Tianjin Medical University General Hospital

Not yet recruiting

Comparison of Remifentanil-induced Postoperative Hyperalgesia Between Patients From Plain Area and Plateau Area

Pain, Postoperative | Anesthesia

China
Second Affiliated Hospital, School of Medicine,...

Recruiting

Intraoperative S-ketamine to Prevent Postoperative Hyperalgesia in Patients Undergoing Video-assisted Thoracic Surgery

Postoperative Hyperalgesia

China
University of Manitoba

Recruiting

Evaluation of a Patient-Centred, Multidisciplinary Opioid Tapering Program for Individuals With Chronic Non-Cancer Pain on Long Term Opioid Therapy

Opioid Use | Pain, Chronic | Hyperalgesia | Opioids; Harmful Use

Canada
Chinese PLA General Hospital
First Affiliated Hospital, Sun Yat-Sen University; Shengjing Hospital; First... and other collaborators

Not yet recruiting

Safety and Efficacy Evaluation of S (+) - Ketamine in Adults

Postoperative Pain | Anesthesia | Adults
Lviv National Medical University

Recruiting

Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations (BBESPB)

Nutrition Disorders | Chronic Pain | Postoperative Pain | Anesthesia, Local | Postoperative Cognitive Dysfunction | Scoliosis | Coagulation Disorder | Acute Pain | Neuropathic Pain | Anesthesia | Postoperative Nausea and Vomiting | Ventilator-Induced Lung Injury | Intraoperative Complications | Hyperalgesia | Regional... and other conditions

Ukraine
University Hospital, Clermont-Ferrand
NEURO-DOL (UMR 1107 INSERM / UCA)

Recruiting

Trial Investigating the Characteristics of Knismesis - a Lever to Explore Allodynia in Neuropathic Pain (TICKLE)

Healthy

France
Hospices Civils de Lyon

Recruiting

Post-operative Analgesic Effect of Oral Nefopam (NefPO)

Postoperative Pain After a Total Knee Arthroplasty

France
Université Catholique de Louvain

Recruiting

Central Sensitisation and Postoperative Pain

Thoracotomy | Hyperalgesia | Electroencephalography | Central Sensitisation | Hyperalgesia, Secondary | Humans | Persistent Postsurgical Pain

Belgium
University of California, Irvine

Recruiting

Effect of Ultra-low Dose Naloxone on Remifentanil-Induced Hyperalgesia

Hyperalgesia

United States
University of California, San Francisco

Completed

Pain Medicine for Wound Care Procedures

Nausea | Vomiting | Hallucinations | Hyperalgesia | Pain Intensity | Wound Care

United States, Puerto Rico
Chinese PLA General Hospital
Shanghai Children's Medical Center; Beijing Children's Hospital; Southern Medical... and other collaborators

Enrolling by invitation

Safety and Efficacy Evaluation of S (+) - Ketamine in Children

Delirium | Postoperative Pain | Analgesia | Children | Acute Pain | Depression, Anxiety | Hyperalgesia | S-ketamine | Esketamine

China
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
Rigshospitalet, Denmark
National Institute on Drug Abuse (NIDA); University of Kentucky

Completed

Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.

Pain | Hyperalgesia | Central Nervous System Sensitization

Denmark
New York State Psychiatric Institute
Alkermes, Inc.

Suspended

Repeated Cannabis Administration on Experimental Pain and Abuse Liability

Pain | Cannabis | Hyperalgesia | Tolerance

United States
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Active, not recruiting

Effect of Guanfacine on the Reversal of Opioid-induced Hyperalgesia (OIH)

Chronic Pain

United States
University of Cape Town
University of Michigan; Brigham and Women's Hospital; Fogarty International Center... and other collaborators

Completed

An Observational Study of Distress, Immune Function, and Pain in HIV.

Chronic Pain | HIV | Distress, Emotional | Central Sensitisation | Immune System and Related Disorders

South Africa
University Hospital, Basel, Switzerland

Completed

Electrical Intra-cutaneous Half-sine Stimulation for Optimized Preferential C-fiber Activation

Pain Perception | Secondary Hyperalgesia

Switzerland
Medical University of Graz

Completed

The Effect of Palmitylethanolamide on Central and Peripheral Sensitization After Heat-induced Hyperalgesia

Pain, Acute | Pain, Chronic | Central Sensitisation | Neuroinflammatory Response

Austria
Wonkwang University Hospital

Completed

The Effect of Remimazolam on Opioid Induced Hyperalgesia

Hyperalgesia, Mechanical

Korea, Republic of
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone

Post Operative Pain | Hyperalgesia

Italy
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Suspended

Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans

Pain | Cannabis | Hyperalgesia | Tolerance

United States
Jazz Pharmaceuticals

Completed

A Study of Sativex® for Pain Relief of Peripheral Neuropathic Pain, Associated With Allodynia

Pain | Peripheral Neuropathy

United Kingdom
Jazz Pharmaceuticals

Completed

A Study of Sativex® for Relief of Peripheral Neuropathic Pain Associated With Allodynia.

Pain | Peripheral Neuropathy

United Kingdom
Balgrist University Hospital

Completed

Differences in Pain Processing Between Men and Women

Central Sensitisation

Switzerland
Massachusetts General Hospital
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Active, not recruiting

Effect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and Tolerance

Chronic Pain

United States
The Second Affiliated Hospital of Chongqing Medical...

Completed

Effect of S-ketamine in Cesarean Section Combined Anesthesia

Postoperative Pain

China
The Second Affiliated Hospital of Chongqing Medical...

Completed

Effect of Daytime Variation on Postoperative Hyperalgesia Induced by Opioids

Postoperative Hyperalgesia

China
ConvaTec Inc.
ClinSearch

Withdrawn

GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter Disorders (FollowAir)

Multiple Sclerosis | Parkinsonian Disorders | Spinal Cord Injuries | Allodynia
University Hospital Schleswig-Holstein

Terminated

Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models

Pain | Hyperalgesia | Allodynia

Germany
Leiden University

Completed

Reducing Nocebo Effects on Pressure Pain

Pain | Hyperalgesia

Netherlands
Lviv National Medical University

Completed

ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY

Chronic Pain | Postoperative Pain | Anesthesia, Local | Postoperative Cognitive Dysfunction | Acute Pain | Neuropathic Pain | Anesthesia | Postoperative Nausea and Vomiting | Intraoperative Complications | Hyperalgesia | Regional Anesthesia Morbidity | Anesthesia Complication | Intraoperative Injury | Intraoperative...

Ukraine
Victor Contreras, MSN

Completed

Comparison of Postoperative Nociception Between NOL-guided and Standard Intraoperative Analgesia Based on Fentanyl (NOLFentanyl)

Pain, Postoperative | Postoperative Pain | Anesthesia | Opioid Use | Nociceptive Pain | Analgesics, Opioid | Allodynia

Chile
Sathbhavana Brain Clinic

Completed

Excessive Crying in Children With Cerebral Palsy and Communication Deficits (ECCCPCD)

Pain | Cerebral Palsy | Excessive Crying
McGill University Health Centre/Research Institute...

Terminated

Genetic Predictors of Analgesic Efficacy of Propranolol for Treating Postoperative Pain (PRO_GENE_POP)

Postoperative Pain

Canada
Tianjin Medical University General Hospital

Completed

Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative Hyperalgesia

Pain | Anesthesia

China
University Hospital, Ghent
University Hospital, Basel, Switzerland

Completed

Hyperalgesia, Persistent Pain, and Fentanyl Dosing in On-Pump Coronary Artery Bypass Grafting

Pain, Postoperative | Opioid Use | Pain, Chronic | Hyperalgesia

Belgium
Seoul National University Hospital

Completed

The Effect of Remifentanil on Rebound Pain

Pain, Postoperative

Korea, Republic of
CRRF La Châtaigneraie
Hôpitaux Universitaires Paris Ile-de-Franc Ouest

Completed

Evaluation of the Efficacy of Somatosensory Rehabilitation of Pain by Vibrotactile Stimulation on Static Mechanical Allodynia (RESISTAL)

Allodynia

France
Seoul National University Hospital

Completed

Gabapentin Pretreatment for Staged Bilateral Cataract Operations

Hyperalgesia | Cataract Bilateral Nos

Korea, Republic of
University Hospital, Basel, Switzerland

Completed

Pain Response to Cannabidiol in Opioid-induced Hyperalgesia, Acute Nociceptive Pain and Allodynia By Using a Model Mimicking Acute Pain in Healthy Adults (CANAB II)

Hyperalgesia | Allodynia | Opioid-induced Hyperalgesia | Acute Nociceptive Pain

Switzerland
University Hospital, Clermont-Ferrand

Unknown

Validation of a Questionnaire for Allodynia in Migraine. (Q-MIGAL)

Migraine

France

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