Search clinical trials for: Immunocompromised

Total 172 results

Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Pembrolizumab in Progressive Multifocal Leukoencephalopathy (PML) in Immunocompromised Patients Without HIV Infection (PENALTY)

Progressive Multifocal Leukoencephalopathy

France
VA Sierra Nevada Health Care System
Merck Sharp & Dohme LLC

Not yet recruiting

Evaluation of PCV15 Vaccination Among PPSV23-experienced, Immunocompromised Elderly Veterans

Immunosuppression | Pneumococcal Vaccines
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
Sichuan Provincial People's Hospital

Not yet recruiting

Efficacy and Safety of the Combination Therapy Based on Eravacycline in Immunocompromised Hosts With MDROS Infection

Immune Dysregulation Disorder
Bart Rijnders

Recruiting

Detection of Azole Resistance Inducing Mutations on DNA Extracted Directly From Serum or Plasma of Immunocompromised Patients With an Invasive Aspergillus Infection Azole Resistance PCR Optimalization-study (ARPO)

Invasive Aspergillosis

Netherlands
ModernaTX, Inc.

Recruiting

A Study to Investigate the Immunogenicity and Safety of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in High-risk Adults

Respiratory Syncytial Virus

Canada, United States, United Kingdom, Puerto Rico
University Hospital, Strasbourg, France

Recruiting

Covid-19 Convalescent Plasma and Monoclonal Antibodies Treatment of Immunocompromised Patients (Covid-IC)

COVID-19 Convalescent Plasma Treatment

France
University Hospital, Montpellier

Recruiting

Comparing High-flow Nasal Cannula Oxygen and Noninvasive Ventilation to Standard Oxygenation in Non-selected ICU Patients Admitted for Hypoxemic ARF (KISS)

Acute Respiratory Failure

France
GlaxoSmithKline
Harvard Pilgrim Health Care Institute

Not yet recruiting

Safety of Herpes Zoster Subunit (HZ/su) Vaccine During Pregnancy in Adult Women With Immunocompromised Conditions

Herpes Zoster
The University of Hong Kong

Recruiting

Intradermal COVID-19 Vaccination in the Immunocompromised

Immunocompromised Patients | Intradermal Covid-19 Vaccine | Immungenicity and Safety | Randomized Trial

Hong Kong
Universiti Putra Malaysia

Recruiting

Invasive Group B Streptococcus Disease Burden and Its Antimicrobial Resistance in Malaysia Among Non-pregnant Adults.

Diabetic Foot | Group B Streptococcal Infections | Immunocompromised Patients | Invasive Infection

Malaysia
University Hospital, Bordeaux
European Commission

Recruiting

Casting Light on HOst-cytomegaloviRUs Interaction in Solid Organ Transplantation (HORUS)

Cytomegalovirus Infections | Solid Organ Transplantation

France
Scripps Translational Science Institute
Cue Health

Recruiting

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

HIV Infections | Lymphoma | Leukemia | Cancer | Multiple Myeloma | Immunosuppression | Immunodeficiency | Transplant | Graft Versus Host Disease | Age-Related Immunodeficiency

United States
First Affiliated Hospital of Guangxi Medical University
Second Affiliated Hospital of Guangzhou Medical University; LiuZhou People's... and other collaborators

Recruiting

PCP in Immunocompromised Population in Southern China (PCP)

Diagnosis | Polymerase Chain Reaction | Immunocompromised Patients | Pneumocystis Pneumonia

China
ANRS, Emerging Infectious Diseases
University Hospital, Geneva

Recruiting

OPtimisation of Antiviral Therapy in Immunocompromised COVID-19 Patients: a Randomized Factorial Controlled Strategy Trial (OPTICOV)

COVID-19 | Immunodeficiency

Switzerland, France
Bayside Health
Monash University

Recruiting

Bringing Optimised COVID-19 Vaccine Schedules To ImmunoCompromised Populations (BOOST-IC): an Adaptive Randomised Controlled Clinical Trial

Lymphoma, Non-Hodgkin | Multiple Myeloma | HIV | Chronic Lymphocytic Leukemia | Organ Transplantation | COVID-19 Vaccines

Australia
Assistance Publique - Hôpitaux de Paris

Recruiting

A Real-World Study of Anti-SARS-CoV-2 Monoclonal Antibodies (COVIMAB)

Immunocompromised Patients

France
University Hospital, Lille

Recruiting

Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical Ventilation (RESPIRE)

Pneumonia, Ventilator-Associated | Immunodeficiency | Pneumonia, Hospital-Acquired

France
GlaxoSmithKline

Recruiting

Study to Monitor the Occurrence of Viral Variants in Patients With Compromised Immune Systems Being Treated for COVID-19 (LUNAR)

COVID-19

United Kingdom
Qilu Hospital of Shandong University
Qianfoshan Hospital; The Second Hospital of Shandong University; Shandong Provincial... and other collaborators

Recruiting

mNGS -Guided Antimicrobial Treatment in Early Severe Community-Acquired Pneumonia Among Immunocompromised Patients (MATESHIP)

Infections | Respiratory Tract Infections | Pneumonia | Community-acquired Pneumonia | Severe Acute Respiratory Infection

China
Paul R Fortin
Canadian Institutes of Health Research (CIHR)

Recruiting

COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases (COVBIRD)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Systemic Vasculitis | Immunosuppression | Scleroderma | Autoimmune Rheumatologic Disease | Undifferentiated Connective Tissue Diseases | Overlap Connective Tissue Disease

Canada
ANRS, Emerging Infectious Diseases

Recruiting

Pre-exposure Prophylaxis of SARS-CoV-2 Infection (COVID-19) by Monoclonal Antibodies With Early Access Authorization in Immunocompromised Patients. A Prospective Cohort. (PRECOVIM)

COVID-19 | Immunocompromised Host

France
Children's National Research Institute

Recruiting

T CELL THERAPY OPPOSING NOVEL COVID-19 INFECTION IN IMMUNOCOMPROMISED PATIENTS (TONI)

SARS-CoV-2 Infection

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Natural History, Epidemiology and Pathogenesis of Severe HPV-Related Diseases (Neptune)

Human Papillomavirus

United States
Cambridge University Hospitals NHS Foundation Trust
GlaxoSmithKline; National Institute for Health Research, United Kingdom; Kidney... and other collaborators

Recruiting

PROphylaxis for paTiEnts at Risk of COVID-19 infecTion -V (PROTECT-V)

Covid19

United Kingdom
M.D. Anderson Cancer Center

Recruiting

Baloxavir and Oseltamivir for the Treatment of Severe Influenza Infection in Immunocompromised Patients

Hematopoietic and Lymphoid Cell Neoplasm | Influenza

United States
Children's National Research Institute

Recruiting

Adoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised Hosts (ATLANTIC)

Viral Infection | Hematopoietic Stem Cell Transplantation (HSCT) | Primary Immunodeficiency Disorders (PID)

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Empirical Steroids and/or Antifungals in Immunocompromised Patients With Acute Respiratory Failure From Undetermined Etiology: a Multicenter Double-blind Randomized Controlled Trial (EFRAIM II)

Acute Respiratory Failure | Immunocompromised Patients
Children's Hospital of Philadelphia

Recruiting

Treatment of BK Virus Infection With CTL Cells in Immunocompromised Transplant Patients (BK-CTLs)

BK Polyomavirus

United States
Ansun Biopharma, Inc.

Recruiting

Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

COVID-19 | Lower Respiratory Tract Infection | Immunocompromised | Parainfluenza

United States, Australia, China, Denmark, France, Hong Kong, Korea, Republic of, Taiwan
University of Wisconsin, Madison
University of Wisconsin Carbone Cancer Center (UWCCC)

Recruiting

Treatment of Cytomegalovirus (CMV) Infections With Viral-Specific T Cells

Cytomegalovirus Infections | Opportunistic Infections | CMV Infection | CMV Viremia

United States
University Hospital, Lille

Recruiting

De-escalation - Antifungal Treatment Immunocompromised Patients (D-ATFIM)

Critical Illness | Invasive Fungal Disease

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor T Cell Therapy in Treating Immunocompromised Patients With Adenovirus-Related Disease

Hematopoietic and Lymphoid Cell Neoplasm | Immunocompromised

United States
AiCuris Anti-infective Cures AG
Medpace, Inc.

Recruiting

Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects (PRIOH-1)

HSV Infection

United States, Italy, Belgium, France, United Kingdom, Germany, Switzerland, Argentina, Australia, Georgia, Greece, Mexico, Israel, Canada
Children's Hospital Medical Center, Cincinnati

Recruiting

Third Party Viral Specific T-cells (VSTs)

Viral Infection | Viral Reactivation | Infection in an Immunocompromised Host

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Viral Infections in Healthy and Immunocompromised Hosts

COVID-19 | Herpes Labialis | Anogenital Herpes

United States
Poitiers University Hospital

Completed

Assessement of Viral Shedding Duration After a Respiratory Tract Infection in Oncology and Hematology Patients (ONCOVIR)

Respiratory Tract Viral Infection

France
AstraZeneca

Active, not recruiting

Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study: Study Understanding Pre-Exposure pRophylaxis of NOVel Antibodies (SUPERNOVA) Sub-study (SUPERNOVA)

COVID-19, SARS-CoV-2

United States, Belgium, Canada, France, Spain, Denmark, Thailand, Vietnam, Korea, Republic of, United Kingdom, Malaysia, Israel, Taiwan, Australia, Germany, Poland, Singapore, United Arab Emirates
Pfizer

Completed

A Study to Assess the Safety, Tolerability, and Immunogenicity of RSVpreF in Adults at High Risk of Severe RSV Disease (MONET)

RESPIRATORY SYNCYTIAL VIRUS (RSV)

United States
Mount Sinai Hospital, Canada
Princess Margaret Hospital, Canada

Active, not recruiting

Low-Flow vs. High-Flow Nasal Cannula for Hypoxemic Immunocompromised Patients During Diagnostic Bronchoscopy

Hypoxia | Hematologic Malignancy | Immunocompromised | Post Hematopoietic Stem Cell Transplant | Pulmonary Infiltrates

Canada
PharmaMar

Active, not recruiting

Plitidepsin Versus Control in Immunocompromised Adult Participants With Symptomatic COVID-19 Requiring Hospital Care (NEREIDA)

COVID-19

Spain, Portugal, France, Belgium, Italy, Greece, Hungary, Georgia, Israel, Poland, United Kingdom
Pfizer

Completed

COVID-19 Vaccination and Breakthrough Infections Among Persons With Immunocompromising Conditions in the United States

Covid-19 | Immunocompromised | Breakthrough Infection | SARS-COV-2 Infection | SARS-COV-2 | Immunosuppressed

United States
Pfizer

Completed

Trial to Describe the Safety, Tolerability, and Immunogenicity of Trumenba When Administered to Immunocompromised Participants ≥10 Years of Age

Meningococcal Vaccine

Poland, Czechia, Turkey
Pfizer

Completed

A Study to Learn About the Study Medicines (Nirmatrelvir Plus Ritonavir) in People Aged 12 Years or Older With COVID-19 and a Compromised Immune System

COVID-19

Spain, United States, Australia, Canada, Bulgaria, Slovakia, Mexico, Hungary, Brazil
University Hospital, Basel, Switzerland
Swiss National Science Foundation; ModernaTX, Inc.

Completed

Immunocompromised Swiss Cohorts Based Trial Platform (COVERALL)

Immunocompromised Patients

Switzerland
AstraZeneca
Aetion, Inc.

Withdrawn

A Non-interventional Multi-country Cohort Study to Assess the Safety of EVUSHELD™ During Pregnancy (O-STEREO)

Pregnancy | Pregnant Women | Pregnancy Outcome
Fundação Bahiana de Infectologia

Completed

Impact of a Dolutegravir-based Regimen on Early Mortality of AIDS Patients (IDEA)

Severely Immunocompromised HIV Patients

Brazil
St. Jude Children's Research Hospital

Completed

A Pilot Study of Influenza Viruses Isolated From Immunocompromised Children and Adolescents

Influenza, Human

United States
AiCuris Anti-infective Cures AG
Impatients N.V. trading as myTomorrows

Available

Expanded Access Intermediate Size Treatment Protocol: Pritelivir for Immunocompromised Subjects With Treatment Resistant Herpes Simplex Virus Type 1 or 2

HSV
AstraZeneca
Iqvia Pty Ltd

Completed

Evaluate the Safety and Tolerability, for Nirsevimab in Immunocompromised Children (MUSIC)

RSV Infection

United States, Belgium, Spain, Japan, Poland, South Africa, United Kingdom, Ukraine

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