Search clinical trials for: Isoniazid

Total 207 results

Brigham and Women's Hospital
University of Cape Town; APIN Public Health Initiatives

Not yet recruiting

Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention

Latent Tuberculosis | Pediatric HIV Infection
Johns Hopkins University
United States Agency for International Development (USAID)

Not yet recruiting

Shortened Regimen for Drug-susceptible TB in Children (SMILE-TB)

Tuberculosis | Tuberculosis, Pulmonary | Mycobacterium Tuberculosis | Tuberculosis, Lymph Node

Uganda, South Africa, Mozambique, Indonesia, Zambia
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); Human Sciences...

Recruiting

ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa (ThiPhiSA)

Tuberculosis

South Africa
National Institute of Allergy and Infectious Diseases...
TB Alliance

Not yet recruiting

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)

Pulmonary Tuberculosis

Botswana, Brazil, Haiti, India, Kenya, Malawi, Mexico, Peru, Philippines, South Africa, Thailand, Uganda, Zimbabwe
Freundeskreis Für Internationale Tuberkulosehilfe...

Not yet recruiting

1HP Versus 3HR in the Treatment of Tuberculosis Infection in Vietnam

Tuberculosis Infection

Vietnam
University College, London
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis

South Africa
Centre Hospitalier Universitaire, Amiens

Recruiting

Relevance of Isoniazid Dosage in Adults Treated for Tuberculosis (ISOBK)

Tuberculosis

France
Huashan Hospital

Recruiting

TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contacts (TB-YOUTH)

Latent Tuberculosis | Tuberculosis

China
Queen Mary University of London
University of Washington; University of Oxford; KEMRI-Wellcome Trust Collaborative... and other collaborators

Not yet recruiting

An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM (Co-SAM)

HIV | Severe Acute Malnutrition | Comorbidities and Coexisting Conditions | Child Malnutrition
Bill & Melinda Gates Medical Research Institute
Global Alliance for TB Drug Development; Janssen Pharmaceutica; Otsuka Pharmaceutical...

Recruiting

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

Pulmonary Tuberculosis

Philippines, South Africa
Indian Council of Medical Research
Christian Medical College, Vellore, India; Jawaharlal Institute of Postgraduate... and other collaborators

Not yet recruiting

Intensified Short Course Regimen for TBM in Adults (INSHORT)

Tuberculous Meningitis

India
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

PanACEA - STEP2C -01

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

Gabon, South Africa, Tanzania, Malawi, Uganda, Mozambique
Centers for Disease Control and Prevention
Tuberculosis Trials Consortium

Recruiting

Short-course Regimens for the Treatment of Pulmonary Tuberculosis (CRUSH-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection

Canada, United States, Haiti, South Africa, Uganda, Vietnam
Brigham and Women's Hospital
University of California, Los Angeles; University of Stellenbosch; University... and other collaborators

Recruiting

Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB (PRESCIENT)

HIV | Tuberculosis, Pulmonary

South Africa, Haiti
TASK Applied Science

Recruiting

A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098 (BETO)

Rifampicin- and Isoniazid-Susceptible Pulmonary Tuberculosis (TB)

South Africa
First Affiliated Hospital of Zhejiang University

Not yet recruiting

Sitafloxacin-containing Regimens for Shortening Tuberculosis Treatment

Tuberculosis, Pulmonary
University of Zurich

Recruiting

Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy

Tuberculosis Infection

Switzerland
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID); Federal University... and other collaborators

Recruiting

Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Prevention

Tuberculosis Infection | Isoniazid Adverse Reaction

Brazil
Rutgers, The State University of New Jersey

Recruiting

One-month Latent Tuberculosis Treatment for Renal Transplant Candidates

End Stage Renal Disease | Latent Tuberculosis | Renal Transplant Candidate for Right Kidney | Renal Transplant Candidate for Left Kidney

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
West China Hospital

Not yet recruiting

The Prophylaxis of Tuberculosis According to TSPOT Results After Kidney Transplantation (PTTKT)

Tuberculosis | Kidney Transplant Infection | Isoniazid Toxicity
Makerere University

Recruiting

Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (PHINX)

Tuberculosis

Uganda
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) (DOLPHIN KIDS)

HIV | Tuberculosis

South Africa
The Aurum Institute NPC
Johns Hopkins University; Weill Medical College of Cornell University; University...

Recruiting

Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV (DOLPHIN Moms)

Pregnancy | HIV Seropositivity | Tuberculosis Infection

South Africa
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients (1 to 3)

Tuberculosis | HIV Seropositivity | Household Contact

South Africa, India, Indonesia, Mozambique
Region Skane

Recruiting

Rifampicin Resistance in S. Aureus During and After Treatment for Latent Tuberculosis

Staphylococcus Aureus | Latent Tuberculosis

Sweden
Miguel Santín
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Not yet recruiting

Short-course Rifamycin-based Regimens for Latent Tuberculosis in Patients With End-stage Kidney Disease

Latent Tuberculosis | Kidney Failure
Institut National de la Santé Et de la Recherche...
National Agency for Research on AIDS and Viral Hepatitis (ANRS)

Not yet recruiting

Impact of Malnutrition on Pharmacokinetic or Rifampicin, Isoniazid, Pyrazinamide and Ethambutol in TB-HIV Co-infected Children (TB-Speed TB-PK)

Tuberculosis | Pulmonary

Uganda, Zambia
University of Cape Town

Recruiting

Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated Tuberculosis (NEW-STRAT TB)

HIV | Disseminated Tuberculosis

South Africa
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
ANRS, Emerging Infectious Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP); European...

Recruiting

Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune Suppression (DATURA)

Tuberculosis | HIV-1-infection | Immuno-Deficiency

Uganda, Cambodia, Cameroon, Guinea, Vietnam, Zambia
Dr. Nyanda Elias Ntinginya
King's College London; Makerere University; Stichting Katholieke Universiteit-... and other collaborators

Recruiting

Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus (PROTID)

Diabetes Mellitus | Tuberculosis

Uganda, Tanzania
Aswan University Hospital

Recruiting

Vaginal Dinoprostone Versus Isonicotinic Acid Hydrazide Prior to Diagnostic Office Hysteroscopy

Postmenopausal Bleeding

Egypt
Seoul National University Hospital
Pusan National University Hospital; Chonnam National University Hospital; Seoul... and other collaborators

Not yet recruiting

Treatment Shortening of Drug-Sensitive Pulmonary Tuberculosis Using High Dose Rifampicin (Hi-DoRi-3) (Hi-DoRi-3)

Tuberculosis, Pulmonary

Korea, Republic of
Fifth Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Efficacy and Safety of Isoniazid, Rifampicin and Moxifloxacin for the Intensive Phase of Initial Therapy of PTB

Pulmonary Tuberculosis

China
University of Florida
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Adequacy of the New Pediatric Isoniazid/Rifampin/Pyrazinamide (HRZ) Tablet

Tuberculosis | Human Immunodeficiency Virus | Coinfection

Ghana
Beijing Chest Hospital

Recruiting

Optimizing Antituberculosis Therapy in Adults With Tuberculous Meningitis

Tuberculous Meningitis

China
Centers for Disease Control and Prevention
Johns Hopkins University; Sanofi; University of Stellenbosch; University of Cape... and other collaborators

Recruiting

Tuberculosis Clinical Trials Consortium Study 35

Latent Tuberculosis

South Africa
Beijing Children's Hospital
Hopital Universitaire Robert-Debre; Shandong University; Rennes University Hospital

Recruiting

Population Pharmacokinetics of Anti-tuberculosis Drugs in Children With Tuberculosis

Tuberculosis

China
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Protecting Households On Exposure to Newly Diagnosed Index Multidrug-Resistant Tuberculosis Patients (PHOENIx MDR-TB)

Tuberculosis, MDR

Haiti, Tanzania, Thailand, Botswana, Brazil, India, Kenya, Peru, Philippines, South Africa, Uganda, Zimbabwe, Vietnam
Centers for Disease Control and Prevention
British Medical Research Council

Recruiting

Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI (ASTERoiD)

Latent Tuberculosis

Australia, United States, Canada, South Africa
Amsterdam UMC, location VUmc

Recruiting

A Phase II/III Study of High-dose, Intermittent Sunitinib in Patients With Recurrent Glioblastoma Multiforme (STELLAR)

Glioblastoma | Glioblastoma Multiforme | GBM | Glioblastoma, Adult | Recurrent Brain Tumor

Netherlands
Medical University of Vienna

Recruiting

PRF With Topical Antibiotics or Antiseptics in Chronical Wounds Version 1.4 (PRF-TAT)

Chronic Skin Ulcer

Austria
National Institute of Allergy and Infectious Diseases...

Completed

Using Biomarkers to Predict TB Treatment Duration

Pulmonary Tuberculosis

South Africa
Global Alliance for TB Drug Development

Completed

Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Tuberculosis, MDR | Drug-Resistant Tuberculosis

Tanzania, Georgia, Russian Federation, Brazil, Malaysia, Philippines, South Africa, Uganda
Yale University
National Institute on Drug Abuse (NIDA); University of Malaya

Active, not recruiting

Addiction, HIV and Tuberculosis in Malaysian Criminal Justice Settings (HARAPAN II)

Hepatitis | HIV/AIDS | Tuberculosis | Addiction | Opioid Dependence

Malaysia
The HIV Netherlands Australia Thailand Research...
King Chulalongkorn Memorial Hospital; Srinagarind Hospital, Khon Kaen University and other collaborators

Active, not recruiting

Tuberculosis Preventive Therapy Among Latent Tuberculosis Infection in HIV-infected Individuals

HIV-infected Participants With Latent TB Infection in High TB Burden Country

Thailand
Institute of Tropical Medicine, Belgium
Damien Foundation

Active, not recruiting

Novel Triple-dose Tuberculosis Retreatment Regimen (Tri-Do-Re)

Tuberculosis | Pulmonary Tuberculosis | Multidrug-resistant Tuberculosis | Resistance to Tuberculostatic Drugs

Niger
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); Makerere University and other collaborators

Completed

Simplified Isoniazid Preventive Therapy Strategy to Reduce TB Burden (SEARCH-IPT)

HIV/AIDS | Tuberculosis

Uganda
Fred Hutchinson Cancer Center
Merck Sharp & Dohme LLC

Completed

Phase I Open Label BCG Clinical Trial Assessing TB Drugs and Vaccines

Tuberculosis

United States

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