Search clinical trials for: Partially matched family member donor transplant

Total 23440 results

St. Jude Children's Research Hospital

Completed

Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias

Anemia, Aplastic | Diamond-Blackfan Anemia | Amegakaryocytic Thrombocytopenia | Kostmann Syndrome

United States
New York Medical College

Completed

CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant

Lymphoma | Leukemia | Sickle Cell Disease | Histiocytosis | Immunodeficiencies | Inborn Errors of Metabolism | Bone Marrow Failure | Beta Thalassemia

United States
Nelson Chao

Terminated

Trial of CMV Specific DLIs From 3-6/6 HLA Matched Family Member Following Nonmyeloablative Allo SCT

Cytomegalovirus Infections

United States
David Rizzieri, MD

Completed

Safety Trial of NK DLI From 6/6 HLA Matched Family Member Following Nonmyeloablative ASCT

Lymphoma

United States
University of Arizona

Completed

Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors

Hematologic Neoplasms | Multiple Myeloma | Anemia, Aplastic | Hemoglobinuria, Paroxysmal

United States
David Rizzieri, MD
Miltenyi Biomedicine GmbH

Completed

Allo Non-Myeloablative SCT Utilizing Mis-Matched Family Member Stem Cells Purged Using Campath

Lymphoma | Leukemia | Solid Tumors | Myelodysplasia | Myeloma

United States
Ossium Health, Inc.
Center for International Blood and Marrow Transplant Research

Recruiting

A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia | Acute Undifferentiated Leukemia | Acute Biphenotypic Leukemia

United States
Byung-Sik Cho

Completed

Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors

Acute Myeloid Leukemia

Korea, Republic of
Children's Hospital of Philadelphia

Completed

CHP 834 Unrelated and Partially Matched Related Donor Peripheral Stem Cell Transportation for T and B Cell Depletion (CliniMACs)

Immunodeficiencies

United States
Ensoma
National Marrow Donor Program

Terminated

MGTA-145 + Plerixafor in the Mobilization of HSCs for Allogeneic Transplant in Hematologic Malignancies

Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Healthy Donors | Related Donors Donating PBSC to a Family Member

United States
Center for International Blood and Marrow Transplant...
Sanofi; Genzyme, a Sanofi Company

Completed

A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor

Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Hodgkin's Disease | Related Donors Donating Peripheral Blood Stem Cells (PBSC) to a Family Member

United States
Karolinska Institutet
Medical University of Vienna; Oslo University Hospital; Sahlgrenska University... and other collaborators

Terminated

Randomized Clinical Study Assessing Haplo vs. URD in AML

Acute Myeloid Leukemia

Canada, Austria, Sweden, Russian Federation, Norway
Columbia University

Active, not recruiting

Stem Cell Transplant in Sickle Cell Disease and Thalassemia

Sickle Cell Disease | Beta Thalassemia

United States
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Leukemia, Myeloid, Acute | Burkitt Lymphoma | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

A Research Study of Bone Marrow Transplantation From Unrelated or Partially Matched Related Donors

Hematological Malignancies

United States
Atara Biotherapeutics
Memorial Sloan Kettering Cancer Center

Completed

Therapeutic Effects of Epstein-Barr Virus Immune T-Lymphocytes Derived From a Normal HLA-Compatible Or Partially-Matched Third-Party Donor in the Treatment of EBV Lymphoproliferative Disorders and EBV-Associated Malignancies

EBV-induced Lymphomas | EBV-associated Malignancies | Transplant Patients With EBV Viremia at High Risk for Developing a Recurrent EBV Lymphoma

United States
Northwell Health
New York Blood Center

Completed

Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies

Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
University of Utah

Terminated

Phase I/II Study of Treg/Tcon Addback to Partially Matched Related Donor Stem Cells With Myeloablative Conditioning and Post-transplant Cyclophosphamide for High Risk Hematologic Malignancies

High Risk Hematologic Malignancies

United States
St. Jude Children's Research Hospital

Completed

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

Hodgkin Lymphoma | Myelodysplastic Syndrome (MDS) | Leukemia, Acute Lymphocytic (ALL) | Juvenile Myelomonocytic Leukemia (JMML) | Leukemia, Myeloid, Acute(AML) | Leukemia, Myeloid, Chronic(CML) | Hemoglobinuria, Paroxysmal Nocturnal (PNH) | Lymphoma, Non-Hodgkin (NHL)

United States
Stanford University

Completed

Stem Cell Transplant From Matched Unrelated or Partially Matched Related Donors

Blood Cancer | Blood and Marrow Transplant (BMT)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cell Selection for Bone Marrow Transplants to Prevent Graft-Versus-Host-Disease

Graft vs Host Disease | Hematologic Neoplasm

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Terminated

Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
St. Jude Children's Research Hospital
Assisi Foundation

Completed

HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies

Acute Myeloid Leukemia | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia | Histiocytosis | Myelodysplasia

United States
St. Jude Children's Research Hospital

Completed

Haploidentical Hematopoietic Stem Cell Transplantation Patients With Wiskott-Aldrich Syndrome

Wiskott-Aldrich Syndrome

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Withdrawn

Reduced Intensity Conditioning Before Partially Matched Donor Stem Cell Transplant in Treating Patients With Advanced Cutaneous T Cell Lymphoma

Recurrent Mycosis Fungoides and Sezary Syndrome | Cutaneous T-Cell Non-Hodgkin Lymphoma | Stage IIB Mycosis Fungoides and Sezary Syndrome | Stage IIIA Mycosis Fungoides and Sezary Syndrome | Stage IIIB Mycosis Fungoides and Sezary Syndrome | Stage IVA Mycosis Fungoides and Sezary Syndrome | Stage...
Sidney Kimmel Cancer Center at Thomas Jefferson...

Terminated

A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives

Lymphoma | Leukemia | Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | AML | Acute Myelogenous Leukemia | Hematologic Malignancy | Myeloma | Non-hodgkin's Lymphoma | CLL | ALL

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Bone Marrow Transplantation of Patients in Remission Using Partially Matched Relative Donor

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia | Aplastic Anemia | Hodgkin's Disease | Biphenotypic Leukemia | Plasma Cell Neoplasms

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

A Two-Step Approach to Bone Marrow Transplant Using Cells From A Partially-Matched Relative

Hematologic Malignancies

United States
David Rizzieri, MD
Miltenyi Biomedicine GmbH

Completed

Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath

Lymphoma | Leukemia | Solid Tumors | Myelodysplasia | Myeloma

United States
University of Sydney
Melbourne Health; Royal Brisbane and Women's Hospital

Unknown

Chemotherapy Followed by Infusion of Partially HLA Matched Unrelated Donor Cells for Patients With AML Who Are Ineligible for Stem Cell Transplantation (SCRAMBLE)

Acute Myeloid Leukaemia

Australia
Colorado Blood Cancer Institute

Unknown

Fludarabine and 400 CGY Total Body Irradiation for Recipients of HLA-Matched or Mis-Matched Family or Unrelated Donor Hematopoietic Stem Cell Transplants Who Have Rejected Their First Allogeneic Stem Cell Transplant

Graft Failure

United States
David Rizzieri, MD

Completed

Safety Trial of NK Cell DLI 3-5/6 Family Member Following Nonmyeloablative ASCT

Lymphoma

United States
Celgene Corporation

Unknown

A Single-arm Safety Study of Transplantation Using Umbilical Cord Blood and Human Placental-derived Stem Cells From Partially Matched Related Donors in Persons With Certain Malignant Blood Diseases and Non-malignant Disorders (HPDSC)

Hematologic Malignancies

United States
St. Jude Children's Research Hospital

Completed

Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies

Lymphoma, Non-Hodgkin | Hodgkin Disease | Chronic Myeloid Leukemia | Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL) | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Myelodysplastic Syndrome (MDS) | Secondary AML | Juvenile Myelomonocytic Leukemia (JMML) | Secondary MDS

United States
St. Jude Children's Research Hospital

Completed

Haploidentical Stem Cell Transplantation for Patients With Hematologic Malignancies

Myelodysplastic Syndrome (MDS) | Leukemia, Acute Lymphocytic (ALL) | Leukemia, Myeloid, Acute(AML) | Leukemia, Myeloid, Chronic(CML) | Hemoglobinuria, Paroxysmal Nocturnal (PNH) | Lymphoma, Non-Hodgkin (NHL) | Juvenile Myelomonocytic Leukemia(JMML)

United States
St. Jude Children's Research Hospital

Completed

Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies

Acute Myeloid Leukemia | Leukemia | Hodgkin's Lymphoma | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Paroxysmal Nocturnal Hemoglobinuria

United States
Colorado Blood Cancer Institute

Unknown

Tacrolimus and MMF as Post Grafting Immunosuppression After Conditioning With Flu TBI for HLA Matched Family Donor

Lymphoma | Multiple Myeloma | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
Children's National Research Institute
The Hospital for Sick Children; Ann & Robert H Lurie Children's Hospital of... and other collaborators

Recruiting

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodY (SUN-RAY)

Sickle Cell Disease

United States
Beijing GoBroad Hospital

Not yet recruiting

CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia | T-Cell Acute Lymphocytic Leukemia
Nantes University Hospital

Not yet recruiting

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation (CY-MET-RIC)

Hematologic Malignancy | Graft Versus Host Disease
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor (OPTISAGE)

GVHD
Peking University People's Hospital

Recruiting

The Optimization of Conditioning Regimen for HLA Matched HSCT in SAA

Severe Aplastic Anemia

China
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

Acute Myeloid Leukemia | Hodgkin Lymphoma | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Hematopoietic and Lymphoid System Neoplasm | Myeloproliferative Neoplasm | Chronic Myeloid Leukemia, BCR-ABL1 Positive

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)

Chronic Granulomatous Disease | CGD

United States
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Recruiting

A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202) (TransIT)

Severe Aplastic Anemia

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

Chronic Granulomatous Disease

United States
Children's Oncology Group

Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States, Australia, Canada
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Up-front Matched Unrelated Donor Transplantation in Pediatric Patients With Idiopathic Aplastic Anemia (UPFRONT-MUD)

Severe Aplastic Anemia | Idiopathic Aplastic Anemia | Moderate Aplastic Anemia Requiring Transfusions
Orca Biosystems, Inc.

Recruiting

Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies (Orca-T)

Acute Myeloid Leukemia | Acute Leukemia | Myelodysplastic Syndrome | Acute Lymphoid Leukemia | Therapy-Related Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia | Undifferentiated Leukemia

United States

Search clinical trials for: Partially matched family member donor transplant

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