Search clinical trials for: Phase+1

Total 59765 results

National Cancer Institute (NCI)

Completed

Phase II Study of the Role of Anti-CEA Antibody Immunoscintigraphy & Positron Emission Tomography in the Localization of Recurrent Colorectal Carcinoma in Patients With Rising Serum CEA Levels in the Absence of Imageable Disease by Conventional Modalities

Colorectal Neoplasm

United States
Kowa Research Institute, Inc.

Completed

Study to Evaluate the Efficacy and Safety of K-877 in Adult Patients With Fasting High Triglyceride Levels and Mild or Moderate Renal Impairment

Severe Hypertriglyceridemia

United States, Czechia, Belarus, Hungary, Russian Federation, Poland, Bulgaria, Georgia, Ukraine
University Hospital, Clermont-Ferrand

Completed

Compared Efficacy and Tolerance of Two Vasopressors Used to Treat Preoperative Hypotension During Carotid Surgery (VP-hTA-XCar)

Endovascular Carotid Surgery | Preoperative Hypotension

France
IWK Health Centre
Duke University

Completed

Preventing Hypotension in Parturients With an Elevated Body Mass Index (BMI)

Hypotension

United States, Canada
Mahidol University

Completed

Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction

Nasal Obstruction Present Finding

Thailand
University of North Carolina, Chapel Hill
National Institute of Mental Health (NIMH); Duke University

Completed

FMRI Brain Activation of Aripiprazole Treatment in Autism Spectrum Disorders (AripfMRI)

Autism Spectrum Disorder

United States
The Cleveland Clinic

Recruiting

Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study (SEAL-IT)

Stage D Heart Failure

United States
Boehringer Ingelheim

Completed

Telmisartan/Amlodipine (80/10) vs. Telmisartan/Amlodipine (40/10) vs. amlodipine10 in Resistant Hypertension

Hypertension

Australia, Austria, Bulgaria, Czech Republic, Ireland, Italy, New Zealand, Russian Federation, Slovakia, Spain, Switzerland, Turkey, Ukraine, United Kingdom
University of Wisconsin, Madison
American Heart Association

Recruiting

A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device

Stroke

United States
National Cancer Institute (NCI)

Active, not recruiting

Screening for Ovarian Cancer in Older Patients (PLCO Screening Trial)

Ovarian Carcinoma | Ovarian Germ Cell Tumor

United States
National Cancer Institute (NCI)

Active, not recruiting

Screening for Prostate Cancer in Older Patients (PLCO Screening Trial)

Prostate Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Screening for Lung Cancer in Older Patients (PLCO Screening Trial)

Lung Carcinoma

United States
University of Wisconsin, Madison

Terminated

A Dose-Escalation Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against CMV in Adult Solid Organ Transplant Recipients

Cytomegalovirus Infections | Solid Organ Transplant

United States
University of Wisconsin, Madison

Withdrawn

SOAR-2: Intervening in Obesity Through Reduction of Dietary Branched Chain Amino Acids (SOAR-2)

Obesity | Diabetes

United States
Kiadis Pharma

Completed

Safety and Efficacy of Donor T-lymphocytes Depleted ex Vivo of Host Alloreactive T-cells (ATIR) in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

Canada, Germany, Belgium, United Kingdom
National Cancer Institute (NCI)

Terminated

Nivolumab in Treating Patients With High-Risk Kidney Cancer Before Surgery

Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Stage III Renal Cell Cancer AJCC v7 | Stage IV Renal Cell Cancer AJCC v7 | Stage II Renal Cell Cancer AJCC v7 | Stage I Renal Cell Cancer AJCC v6 and v7

United States
Venatorx Pharmaceuticals, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

VNRX-5133 SAD/MAD Safety and PK in Healthy Adult Volunteers

Bacterial Infections

United States
Aarhus University Hospital Skejby

Completed

The GRAFT Study: Evaluation of Graft Function, Rejection and Cardiac Allograft Vasculopathy in First Heart Transplant Recipients.

Heart Transplant Recipients

Denmark
Ministry of Science and Technology, India

Completed

Efficacy and Safety of Immunomodulator as an Adjunct Therapy in New Pulmonary Tuberculosis(Category I) Patients.

Tuberculosis

India
University of Aarhus
Spirare ApS

Completed

Efficacy and Safety of Nasal Filters on Seasonal Allergic Rhinitis (Hay Fever)

Rhinitis, Allergic, Seasonal

Denmark
University Health Network, Toronto
United States Department of Defense

Completed

Breast Study to Determine the Ability of Non-Invasive Optical Transillumination Spectroscopy to Predict Breast Density.

Breast Cancer

Canada
Groupe Francophone des Myelodysplasies
Celgene

Recruiting

Study Evaluating Combination of Luspatercept in LR-MDS Without RS Having Failed or Being Ineligible to ESA

Myelodysplastic Syndromes | MDS

France
Fondazione Italiana Linfomi - ETS

Active, not recruiting

Copanlisib With Rituximab-Bendamustine in Patients With Relapsed-Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-cell Lymphoma

Italy
Pfizer

Terminated

An Investigational Drug, Crizotinib (PF-02341066), Is Being Studied In Tumors, Except Non-Small Cell Lung Cancer, That Are Positive For Anaplastic Lymphoma Kinase (ALK)

Neoplasms Malignant

United States, Korea, Republic of, Japan, China, Taiwan, Italy, Russian Federation
Pfizer

Terminated

An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis (POLARIS)

Brain Metastases

United States, Belgium, Australia, Argentina, Italy
Fondazione Italiana Linfomi ONLUS

Completed

Fase II Study With BRB for Non-Hodgkin Lymphoplasmacytic Lymphoma/Waldenstrom Macroglobulinemia's (FIL_BRB)

Waldenstrom's Macroglobulinemia

Italy
Ipsen

Completed

Study to Evaluate Smecta® vs Placebo on the Time to Recovery Following an Acute Diarrhoea Episode in Adults

Diarrhea

Morocco, Tunisia
NeuromaxBionevia

Completed

12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Controlled Study (DE-DPN)

Diabetic Peripheral Neuropathy

Russian Federation
Fondazione IRCCS Istituto Nazionale dei Tumori,...

Completed

Chemotherapy Plus Surgery in Treating Women With Breast Cancer

Breast Cancer

Spain, Poland, Italy, Austria, Russian Federation, Slovakia, Hungary, Germany, Czech Republic, Estonia, Latvia
Anthera Pharmaceuticals

Completed

PLASMA Trial: A Dose-Response Study of A-002 In Subjects With Stable Coronary Artery Disease (PLASMA)

Coronary Artery Disease (CAD)

United States, Ukraine
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic Cancers

Metastatic Cancer | Advanced Cancer

United States
Dompé Farmaceutici S.p.A
Covance

Completed

Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers (NGF0112)

Healthy

Switzerland, United Kingdom
Bristol-Myers Squibb

Terminated

A Dose Escalation and Combination Immunotherapy Study to Evaluate BMS-986226 Alone or in Combination With Nivolumab or Ipilimumab in Patients With Advanced Solid Tumors

Cancer | Neoplasm | Tumors | Malignancy

United States, Canada, Spain, Switzerland
University of Virginia

Terminated

Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) (UVA-Gen001)

Soft Tissue Sarcoma | Lymphoma | Neuroectodermal Tumors, Primitive | Brain Neoplasms | Hodgkin Lymphoma | Solid Tumor | Ewing Sarcoma | Non-Hodgkin Lymphoma | Medulloblastoma | Medulloblastoma, Childhood | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Germ Cell Tumor | Childhood Solid Tumor | Childhood Lymphoma

United States
Washington University School of Medicine
Foundation for Anesthesia Education and Research

Completed

Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia (Mini-VINO)

Cardiovascular Abnormalities

United States
Virginia Clinical Research, Inc.
Celgene Corporation

Unknown

Pilot Study of Apremilast (CC-10004) in the Treatment of Moderate to Severe Lichen Planus

Lichen Planus

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Agatolimod Sodium, Rituximab, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Recurrent or Refractory Non-Hodgkin Lymphoma

Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenstrom Macroglobulinemia | Recurrent... and other conditions

United States
Pharvaris Netherlands B.V.

Recruiting

Study of Oral Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema (RAPIDe-3)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Tribhuvan University Teaching Hospital, Institute...

Completed

Comparison of Phenylephrine and Norepinephrine for Spinal-induced Hypotension

Spinal Induced-hypotension

Nepal
Applied Biology, Inc.

Completed

Study to Investigate the Effect of AB-101 in Breast Cancer Survivors

Breast Cancer | Sexual Dysfunction | Sexual Dysfunction, Physiological | Neuropathy | Cancer of Breast | Sexual Arousal Disorder | Nipple Disorder

United States
Combined Military Hospital, Pakistan

Recruiting

Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis (children)

Acute Bronchiolitis Due to Respiratory Syncytial Virus

Pakistan
University of Aarhus

Recruiting

Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia (IMPACT)

Hypotension

Denmark
General Hospital of Ningxia Medical University

Not yet recruiting

Phenylephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia

Adverse Effect
Peking Union Medical College Hospital

Not yet recruiting

Pyrotinib Combined With Trastuzumab and AI in the First-line Treatment of HER2 Positive/ HR Positive MBC (Pyrotinib)

Breast Diseases | Metastatic Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Breast Cancer Female | Hormone Receptor Positive Tumor
Minia University

Completed

Dexmedetomidine in Splanchnic Nerve Neurolysis

Dexmedetomidine

Egypt
Emory University

Completed

Bacteriostatic Normal Saline Versus Lidocaine for Intradermal Anesthesia

Chronic Pain

United States
Otsuka Pharmaceutical Development & Commercialization...
H. Lundbeck A/S; PRA Health Sciences

Completed

A Trial of Single- and Multiple-doses of Aripiprazole in Adult Subjects With Schizophrenia or Bipolar I Disorder

Schizophrenia | Bipolar I Disorder

United States
University of Maryland, Baltimore

Completed

Double-Blind Placebo Controlled Study of Adjunctive Aripiprazole for Symptomatic Hyperprolactinemia In Premenopausal Women With Schizophrenia (DAAMSEL)

Hyperprolactinemia

United States
Maimonides Medical Center

Withdrawn

Dobutamaine Versus Milrinone in Cardiorenal Syndrome (DOMICAS)

Cardiorenal Syndrome

United States

Search clinical trials for: Phase+1

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