Search clinical trials for: Physiological Effects of Drugs

Total 446639 results

MedSIR
Stemline Therapeutics, Inc.

Not yet recruiting

Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. (ADELA)

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation
Centre Hospitalier Universitaire, Amiens
University Hospital, Rouen; University Hospital, Lille

Recruiting

Non-steroidal Anti-inflammatory in Cardiac Surgery (KETOPAIN)

Cardiac Surgery | Acute Postoperative Pain | Pain Intensity | Multimodal Pain Management | Non-steroidal Anti-inflammatory Drugs

France
University Hospital, Tours

Not yet recruiting

Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial- (PROTO-EHPAD)

Depression | Neurocognitive Disorders
University of Redlands

Not yet recruiting

Pharmacokinetics of Melatonin Administered in Oral, Lotion, and Bubble Bath Formulations

Sleep

United States
University of Florida

Not yet recruiting

Examining the Impact of High-protein Oral Supplement With Liposomal Curcumin on Inflammation Markers and Oxidative Stress in Adults Undergoing Hemodialysis.

Chronic Kidney Disease 5D
Zoya Haitov Ben Zikri

Recruiting

Levels of Fear, Anxiety and Wound Healing Among Aental Surgery Patients Under Local Versus General Anesthesia

Wisdom Teeth Extraction or Jaw Implant

Israel
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Recruiting

The Clinical Efficacy and Safety of Finerenone in the Treatment of Primary Aldosteronism

Primary Aldosteronism | Mineralocorticoid Receptor Antagonist | Finerenone

China
Primus Pharmaceuticals
Sun Valley Arthritis Center

Recruiting

Effect of Metaxalone 640 mg (M640) on Truck Driving Ability and Cognition Compared to Other Skeletal Muscle Relaxants

Cognitive Impairment

United States
Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine for Antimuscarinic Delirium: a Randomized, Placebo-controlled Trial (RIVA-AM)

Anticholinergic Toxicity

United States
Children's Hospital of Fudan University

Not yet recruiting

Thalidomide Therapy for VEOIBD

Inflammatory Bowel Diseases
Nordsjaellands Hospital

Recruiting

Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block

Anesthesia, Local | Surgery | Brachial Plexus Block | Nerve Block | Forearm Fracture

Denmark
BioMarin Pharmaceutical

Not yet recruiting

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

Idiopathic Short Stature
Fayoum University Hospital

Recruiting

Low Dose Bupivacaine Versus Prilocaine Regarding Hemodynamic Stability and Safety in Geriatrics

Recruitment

Egypt
Air Force Military Medical University, China

Not yet recruiting

Diagnosis of Depressive Disorder Malinger Using the Niacin Skin Response Test (NSRT)

Depressive Disorder | Malingering

China
Montefiore Medical Center

Not yet recruiting

Antiemetic Fosaprepitant To Remedy Nausea and Vomiting: A Randomized Control Trial (AFTR NV RCT)

Nausea | Vomiting | Nausea and Vomiting

United States
Instituto Nacional de Ciencias Medicas y Nutricion...
Emory University; Universidad Nacional Autonoma de Mexico

Recruiting

Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA) (MEBP-OSA)

Obstructive Sleep Apnea of Adult

Mexico
Wayne State University

Not yet recruiting

Warrior CARE: Cannabis Behavioral Health (CBH)

Suicide | Post Traumatic Stress Disorder | Cannabis Use | Veterans | Marijuana

United States
Indonesia University

Not yet recruiting

Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery

Anesthesia and Analgesia | Anesthesia, Endotracheal
Chung-Ang University Gwangmyeong Hospital

Not yet recruiting

Comparison of Remimazolam and Propofol Combination vs. Propofol in IOM

Neurologic Disorder
Cairo University

Not yet recruiting

Bupivacaine 0.125% Versus Bupivacaine 0.25% in Superficial Cervical Plexus Block on Operative Field Visibility for Adults Undergoing Tympanomastoid Surgeries

Surgical Field Visualization, Acute Postoperative Pain
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer

Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Locally Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Adenocarcinoma

United States
University Health Network, Toronto
GlaxoSmithKline

Not yet recruiting

Belimumab in Autoimmune Hepatitis (BELief)

Autoimmune Hepatitis
AstraZeneca

Not yet recruiting

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Advanced Breast Cancer

Canada
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
Northwell Health

Recruiting

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Pain, Postoperative | Postoperative Pain, Acute

United States
Isfahan University of Medical Sciences

Not yet recruiting

Effectiveness of Intrauterine Growth Hormone Administration as an add-on Therapy to Conventional Hormone Therapy Compared to Placebo in Patients With Thin Endometrium Undergoing Frozen Thawed Embryo Transfer

Infertility | Thin Endometrium | Infertility Female

Iran, Islamic Republic of
Nordsjaellands Hospital

Recruiting

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Colles' Fracture | Fracture Dislocation | Distal Radius Fractures | Lidocaine | Ropivacaine | Closed Reduction of Fracture and Application of Plaster Cast

Denmark
Jagiellonian University

Recruiting

Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery

Anesthesia, General | Analgesics, Opioid | Anesthesia, Endotracheal

Poland
Johns Hopkins University
National Institutes of Health (NIH)

Not yet recruiting

Behavioral Pharmacology of Orally Administered THC and D-limonene

THC | Subjective Drug Effects | D-limonene

United States
Modern Biosciences Ltd

Not yet recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Al-Balqa Applied University
Luzmila Hospital

Not yet recruiting

Intermittent Boluses Versus Infusion of Propofol During Gastroscopy

Anesthesia
Mayo Clinic

Not yet recruiting

Stereotactic Body Radiation Therapy Plus Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy for Treatment of Metastatic, Recurrent Hormone-Sensitive Prostate Cancer, DIVINE Trial (DIVINE)

Recurrent Prostate Cancer | Castration-resistant Prostate Cancer | Stage IVB Prostate Cancer AJCC v8 | Recurrent Castration-Sensitive Prostate Carcinoma

United States
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

Obesity | Atypical Endometrial Hyperplasia | Endometrial Neoplasms | Progesterone Resistance

China
HALEON

Not yet recruiting

A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain

Pain
I.R.C.C.S. Fondazione Santa Lucia

Not yet recruiting

Oral Supplementation Compared With Hyaluronic Acid Infiltration in Rotator Cuff Tendinopathies

Shoulder Pain | Dietary Supplements | Hyaluronic Acid | Tendinitis of Shoulder
Incyte Corporation

Recruiting

A Study to Evaluate the Drug Interaction Between Povorcitinib and the Oral Contraceptive Levonorgestrel/Ethinyl Estradiol in Healthy Adult Females

Healthy Participants

United States
University of Novi Sad

Recruiting

Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery

Acute Kidney Injury

Serbia
Novartis Pharmaceuticals

Not yet recruiting

NEPC Study: An Exploratory Safety and Efficacy Study With PSMA, SSTR2 and GRPR Targeted Radioligand Therapy in Metastatic Neuroendocrine Prostate Cancer.

Metastatic Neuroendocrine Prostate Cancer
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use (ROLDI)

Opioid Use Disorder
HALEON

Recruiting

A Clinical Study to Evaluate the Anti-Sensitivity Effect of a Calcium Sodium Phosphosilicate Toothpaste in a Population of Dentin Hypersensitivity Sufferers

Dentin Sensitivity

Canada
Centre Hospitalier Departemental Vendee

Not yet recruiting

Hyaluronic Acid in Shoulder Tendinopathy (ACCTE)

Shoulder Tendinitis

France
National University of Malaysia

Not yet recruiting

Efficacy & Safety of Dry Powder Ivy Extract (Syrup Prospan) Versus NAC Among COPD Patients (SyProNAC)

Chronic Obstructive Pulmonary Disease

Malaysia
University Hospital, Ghent
Filament Health

Not yet recruiting

Psilocybin for Hospitalized Patients With Treatment-resistant Depression (PSIHOS-D)

Treatment Resistant Depression

Belgium
Masonic Cancer Center, University of Minnesota

Not yet recruiting

MT2022-60: Ph 2 Study of Pembro+ BEAM With ASCT for Relapsed Hodgkin Lymphoma

Classic Hodgkin Lymphoma | Autologous Stem Cell Transplant
RemeGen Co., Ltd.

Not yet recruiting

To Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravesical Instiliations of Disitamab Vedotin in Patients With High-risk Non-muscular Invasive Bladder Cancer (NMIBC) That Express HER2

High-risk Non-muscle Invasive Bladder Cancer

China
University of Wisconsin, Madison

Not yet recruiting

Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)

Posttraumatic Stress Disorder

United States
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy

Colorectal Neoplasia

United States
Teoxane SA

Not yet recruiting

RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)

Pain | Aging

United States
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Helwan University

Recruiting

Role of Calcium Chloride Injection in Alleviating Atrial Fibrillation Post CABG

Atrial Fibrillation

Egypt

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