Search clinical trials for: Pravastatin

Total 172 results

Children's Mercy Hospital Kansas City
Indiana Clinical and Translational Sciences Institute

Recruiting

IMProving DRug Dosing and Outcomes for Single VEntricle Patients With Fontan Associated Liver Disease (IMPROVE-FALD)

Fontan Circulation

United States
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
Jaime Daniel Mondragon
University Medical Center Groningen; Hospital General León; Hospital General...

Recruiting

Dapagliflozin Effect in Cognitive Impairment in Stroke Trial (DECIST)

Metabolic Syndrome | Mild Cognitive Impairment | Dementia, Vascular | Stroke, Ischemic

Mexico
Children's Hospital Medical Center, Cincinnati

Recruiting

Pravastatin as a Prophylactic to Reduce Endothelial Injury in Pediatric Patients With Elevated Body Mass Index

Hematopoietic Stem Cell Transplant (HSCT) | Endothelial Injury

United States
Peking University Third Hospital

Not yet recruiting

Pravastatin Reduces Acute Phase Response of Zoledronic Acid

Postmenopausal Osteoporosis
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Recruiting

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma

Diffuse Large B-Cell Lymphoma | High-grade B-cell Lymphoma | Double Expressor Lymphoma | High Grade B-Cell Lymphoma w/MYC & BCL2 or BCL6 Rearrangements | High Grade B-Cell Lymphoma w/MYC, BCL2 & BCL6 Rearrangements

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Recruiting

Improving Theempowerment in Patients With Severe Breast Fibrosis Radio-induced Treated by Pravastatin : Benefit of e-PROs (Electronic " Patient Reported Outcome ") on Breast-related Quality of Life (PRAVACUR-02)

Breast Cancer

France
McMaster University
Canadian Cancer Society (CCS); Prostate Cancer Canada

Recruiting

A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (RADICALPC)

Cardiovascular Disease | Prostate Cancer

United States, Canada, Australia, Brazil, Israel, Turkey, Colombia
Mylan Pharmaceuticals Inc
Genpharm ULC

Completed

Fasting Bioequivalence Study of Pravastatin Sodium 80 mg Tablets Versus Pravachol® 80 mg Tablets In Normal Healthy Subjects

Therapeutic Equivalency

Canada
Mylan Pharmaceuticals Inc
Genpharm ULC

Completed

Fed, Bioequivalence Study of Pravastatin Sodium 80 mg Tablets Versus Pravachol® 80 mg Tablets In Subjects

Therapeutic Equivalency

Canada
Pachankis, Yang I., M.D.
First Affiliated Hospital of Chongqing Medical University

Completed

Detoxification From the Lipid Tract

COVID-19 Vaccine Adverse Reaction

China
University of Colorado, Denver

Active, not recruiting

Statin Therapy in Patients With Early Stage ADPKD

Autosomal Dominant Polycystic Kidney | ADPKD

United States
Daiichi Sankyo
Daiichi Sankyo Korea Co., Ltd.

Active, not recruiting

An Observational Study Investigating the Change in Blood Cholesterol With Mevalotin® Tablet Administration in Korean Menopausal Women Aged 50 Years or More Who Require Treatment of Dyslipidemia

Dyslipidemia

Korea, Republic of
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With Polatuzumab Vedotin in B-Cell Non-Hodgkin Lymphoma

B-cell Non-Hodgkin Lymphoma

United States, Canada, Belgium, Spain, United Kingdom
Istituto Auxologico Italiano
European Society of Hypertension; Chinese Hypertension League

Completed

Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives (ESH-CHL-SHOT)

Stroke | Hypertension | Transient Ischemic Attack

Russian Federation
ViiV Healthcare

Completed

Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy Adults

HIV Infections

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate the Drug-drug Interaction Potential of BMS-986196 in Healthy Participants

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...

Completed

StAT-TB (Statin Adjunctive Therapy for TB): A Phase 2b Dose-finding Study of Pravastatin in Adults With Tuberculosis

Tuberculosis | Pulmonary Tuberculosis

South Africa
The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Pravastatin to Prevent Preeclampsia (Pravastatin)

Obstetric Labor Complications | Preeclampsia | Hypertension in Pregnancy

United States
Institut du Cancer de Montpellier - Val d'Aurelle

Terminated

A Comparative Study of Pravastatin vs Placebo as Primary Prevention of Severe Subcutaneous Breast Fibrosis in Hyper-radiosensitive Identified Patients With Breast Cancer (PRAVAPREV-01)

Breast Cancer

Monaco, France
Johns Hopkins University

Completed

Statin Adjunctive Therapy for TB (StAT-TB)

Tuberculosis

South Africa
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial

Hematopoietic and Lymphoid Cell Neoplasm | Sarcoma | Lymphoma | Breast Carcinoma

United States
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Hypercholesterolaemia

Czechia, France, Denmark, Netherlands, Austria, Mexico, Spain, United States, Argentina, Brazil, Bulgaria, Canada, Finland, Hungary, Italy, Lebanon, Norway, Poland, Russian Federation, Slovenia, South Africa, Sweden, Taiwan, Turkey
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S0919 Idarubicin, Cytarabine, and Pravastatin in Treating Patients With Relapsed Acute Myeloid Leukemia

Leukemia

United States
The University of Texas Medical Branch, Galveston
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Active, not recruiting

Pravastatin for Prevention of Preeclampsia (Statin)

Preeclampsia

United States
Reuven Schore
Millennium Pharmaceuticals, Inc.; Hyundai Hope On Wheels

Terminated

Monitoring and Treatment of Relapsed Leukemia Following Allogeneic Hematopoietic Stem Cell Transplantation in Children

Leukemia

United States
Boston Children's Hospital
Merck Sharp & Dohme LLC; Schering-Plough; Eiger BioPharmaceuticals

Active, not recruiting

Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

Progeria

United States
University of Southern California

Enrolling by invitation

Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease (ADPKD-SAT)

Autosomal Dominant Polycystic Kidney Disease

United States
Matthew Feinstein

Completed

High Intensity Lipid Lowering Following Acute Coronary Syndromes for Persons Living With HIV (HILLCLIMBER)

HIV Infection | Coronary Heart Disease

United States
Brigham and Women's Hospital

Completed

Effect of Statin Use on Aldosterone Secretion

Healthy Subjects

United States
University of Cologne
German Federal Ministry of Education and Research

Completed

Statin Recapture Therapy Before Coronary Artery Bypass Grafting (StaRT-CABG)

Coronary Artery Disease

Germany
Gilead Sciences
Galapagos NV

Completed

Study to Evaluate Organic Anion Transporting Polypeptide (OATP) Transporter-Mediated Drug-Drug Interactions Between Filgotinib and Statins as Probe Drugs in Healthy Participants

Rheumatoid Arthritis

United States
Amarin Pharma Inc.

Completed

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (MARINE)

Hypertriglyceridemia

United States, Netherlands, Russian Federation, Ukraine, Denmark, Finland, Germany, India, Italy, Mexico, South Africa
Amarin Pharma Inc.

Completed

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (ANCHOR)

Hypertriglyceridemia

United States
Amarin Pharma Inc.

Completed

A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin (REDUCE-IT)

Cardiovascular Diseases

United States, Australia, Canada, India, Netherlands, New Zealand, Poland, Romania, Russian Federation, South Africa, Ukraine
Hospital Israelita Albert Einstein
Novartis; epHealth

Completed

Real World Evidence Study of Statin Use in Brazil (RWE-Statins)

Myocardial Infarction | Cardiovascular Diseases | Stroke | Hypertension | Diabetes Mellitus | Dyslipidemias

Brazil
Organon and Co

Completed

A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)

Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)

Hypercholesterolemia
University of Maryland, Baltimore

Completed

Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition

Bile Salt Export Pump (BSEP) Transporter | Polysorbate 80

United States
Daiichi Sankyo, Inc.
Daiichi Sankyo Korea Co., Ltd.

Completed

An Observational Study Investigating the Effectiveness of Pravastatin on Renal Function in Korean Dyslipidemic Patients With Type 2 Diabetes

Dyslipidemia Associated With Type II Diabetes Mellitus

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids

HIV Infections | Lipodystrophy

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower the Level of Fat in Your Blood

HIV Infections

United States
Cedars-Sinai Medical Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence

Hepatocellular Carcinoma | Liver Cirrhoses

United States
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Hypercholesterolemia

Slovenia, Taiwan, Russian Federation, Canada, Netherlands, Brazil, Denmark, Mexico, Spain, Turkey
Kala Pharmaceuticals, Inc.

Completed

Exploratory Study of KPI-121 Effect on Intra- or Subretinal Fluid Due to Retinal Vein Occlusion/Diabetic Macular Edema (Molokini)

Diabetic Macular Edema | Retinal Vein Occlusion

United States
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

The Influence of Raltegravir on Pravastatin Pharmacokinetics(GRAPPA) (GRAPPA)

HIV Infections

Netherlands
Teva Pharmaceuticals USA

Completed

Bioavailability Study of Pravastatin Sodium 40 mg Tablets Under Fasting Conditions

Healthy

Canada
Scynexis, Inc.
Clinical Network Services (CNS) Pty Ltd

Completed

Study to Evaluate the Effect of SCY-078 (Ibrexafungerp) on the PK of Pravastatin in Healthy Subjects

Pharmacokinetics

Australia
Dr. Robert F. Casper

Withdrawn

Statins: A New Therapeutic Option for Treatment of Patients With Endometriosis

Endometriosis

Canada
Federation Francophone de Cancerologie Digestive
Centre Hospitalier Universitaire Dijon

Completed

Sorafenib Tosylate With or Without Pravastatin in Treating Patients With Liver Cancer and Cirrhosis

Liver Cancer

France

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