Search clinical trials for: RET-PTC4

Total 217 results

Hoffmann-La Roche

Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW)

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Endocrine System Diseases | Gastrointestinal Neoplasms | Neoplasms, Germ Cell and Embryonal | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Respiratory Tract... and other conditions

France, Spain, United States, Korea, Republic of, United Kingdom, Taiwan, China, Belgium, Singapore, Netherlands, Germany, Italy, Hong Kong
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001) (LIBRETTO-001)

Non-Small Cell Lung Cancer | Colon Cancer | Medullary Thyroid Cancer | Any Solid Tumor

United States, Japan, Taiwan, Australia, Korea, Republic of, Israel, Spain, Switzerland, Singapore, France, Canada, Italy, Germany, United Kingdom, Hong Kong, Denmark
Loxo Oncology, Inc.
Eli Lilly and Company

Recruiting

A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors (LIBRETTO-121)

Soft Tissue Sarcoma | Medullary Thyroid Cancer | Papillary Thyroid Cancer | Infantile Fibrosarcoma | Infantile Myofibromatosis

United States, Australia, Japan, Canada, Germany, Korea, Republic of, France, Spain, United Kingdom, Denmark, Italy
Hoffmann-La Roche

No longer available

Expanded Access to RXDX-105 for Cancers With RET Alterations

Cancers With RET Alterations

United States
Applied Pharmaceutical Science, Inc.

Recruiting

A Study of APS03118 in Advanced Solid Tumors Harboring RET Mutations or Fusions

RET-altered Solid Tumors

China
Federal State Budgetary Organization, Federal Center...
Chuvash State University named after I.N. Ulyanov

Completed

Rational-emotional Behavioral Therapy (REBT) in Patients With Osteoarthritis and Concomitant Diseases Before Arthroplasty (REBT)

Pain | Depression, Anxiety

Russian Federation
Hoffmann-La Roche

Active, not recruiting

A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) (AcceleRET-Lung)

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Germ Cell and Embryonal | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Bronchial Diseases | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Neoplasms, Nerve... and other conditions

Italy, Korea, Republic of, Australia, Spain, Argentina, Belgium, Brazil, France, Portugal, United Kingdom, United States, Japan, Mexico, Poland, Norway, Costa Rica, Switzerland, Netherlands, Germany, Sweden, Turkey, Ireland, Panama
Teoxane SA

Completed

RHA® 3 Versus Restylane-L® for Lip Augmentation

Lip | Lip Augmentation

United States
University of Miami

Completed

Restorative Eye Treatment and INhance in Upper Eyelid Blepharoplasty Surgery

Dermatochalasis | Eyelid Dermatochalasis

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Targeted Treatment for RET Fusion-Positive Advanced Non-Small Cell Lung Cancer (A LUNG-MAP Treatment Trial)

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Recurrent Lung Non-Small Cell Carcinoma

United States
Dieter Manstein, MD

Completed

Assessment and Augmentation of Lip Appearance in Specific Study Populations

Lip | Lip Augmentation | Lip Aging

United States
University of Nottingham

Active, not recruiting

Assessing the Impact of Age, and a Short-term High-intensity Interval Training (HIIT) on Skeletal Muscle Mass and Mitochondrial Activity (Mi-HIIT)

Sarcopenia | Aging

United Kingdom
University of Michigan Rogel Cancer Center

Completed

Benefits of Exercise Training in Head and Neck Cancer Patients Undergoing Organ-Preserving Definitive Therapy

Head and Neck Squamous Cell Carcinoma

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Faceland Clinics

Completed

Four Hyaluronic Acid Fillers for Lip Augmentation

Lip

Netherlands
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Terminated

Ponatinib for Advanced Medullary Thyroid Cancer

Thyroid Neoplasms

United States
Shouyao Holdings (Beijing) Co. LTD

Recruiting

Phase I/II Study of SY-5007, a RET Inhibitor, in Patients With RET-altered Advanced Solid Tumor

Non-Small Cell Lung Cancer | Solid Tumor | Medullary Thyroid Cancer

China
Babes-Bolyai University

Completed

Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems (REBTonAd)

Anxiety Disorders | Generalized Anxiety Disorder | Major Depressive Disorder | Social Anxiety Disorder | Panic Disorder | Persistent Depressive Disorder

Romania
Sameek Roychowdhury

Active, not recruiting

Ponatinib for Patients Whose Advanced Solid Tumor Cancer Has Activating Mutations Involving the Following Genes: FGFR1, FGFR2, FGFR3, FGFR4, RET, KIT.

Malignant Neoplasm

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Active, not recruiting

Behavioral Memory Modulation in Nicotine Addiction

Nicotine Use Disorder

United States
Massachusetts General Hospital

Completed

Ponatinib in Advanced NSCLC w/ RET Translocations

Non Small Cell Lung Cancer

United States
Riphah International University

Completed

Effects of Pursed Lip Breathing Technique Versus Stacked Breathing Technique Among Chronic Bronchitis Patients

Chronic Bronchitis

Pakistan
Shouyao Holdings (Beijing) Co. LTD

Recruiting

Phase III Study of SY-5007, a RET Inhibitor, in Patients With Locally Advanced or Metastatic RET Fusion-positive NSCLC

Non-Small Cell Lung Cancer

China
Implantology Institute

Completed

Facial Scanning for Lip Support Assessment in Full Arch Implant Rehabilitations

Prosthesis User | Lip | Soft Tissue

Portugal
University of Colorado, Denver
Janssen Research & Development, LLC

Recruiting

Amivantamab With Tyrosine Kinase Inhibitors (TKI) for Advanced NSCLC With ALK, ROS1, or RET Alterations

Lung Cancer | Non Small Cell Lung Cancer

United States
Eyenez LLC

Completed

Clinical Equivalency Validation Protocol Clinical Equivalency Eyenez Retina Camera v200 and Optomed Smartscope M5 EY3

Diabetes
Croma-Pharma GmbH
Proinnovera GmbH

Not yet recruiting

THIODERM ELATE for Volume Augmentation in Lips (TIVOLI)

Lip; Anomaly

Austria
Ellipses Pharma

Recruiting

A Study of EP0031 in Patients With Advanced RET-altered Malignancies

Advanced Solid Tumor

United States, Spain, United Kingdom
National Taiwan University Hospital

Not yet recruiting

Detecting the Changes of Swallowing Function in Tongue Cancer Patients Receiving Mandibular-lip Split or Pull-through Resection Surgeries

Swallowing Function
Samsung Medical Center
AstraZeneca

Completed

Vandetanib in Advanced NSCLC With RET Rearrangement

Non Small Cell Lung Cancer

Korea, Republic of
University of Nottingham
University of Birmingham

Unknown

The Effect of Very Low Calorie Diet With and Without Exercise on Muscle Synthesis in Middle-aged Overweight Male. (VLCDex)

Overweight and Obesity

United Kingdom
ETOP IBCSG Partners Foundation
Hoffmann-La Roche

Terminated

ALEctinib for the Treatment of Pretreated RET-rearranged Advanced Non-small Cell Lung Cancer (ALERT-lung)

Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Lung Cancer Recurrent

Ireland, Spain, Belgium, Italy, Netherlands, Switzerland
Nantes University Hospital

Unknown

"Impact of a Programme to Improve Interaction Among Professionals on the Management of Task Interruptions" (IMPACTT)

Quality of Life

France
Implantology Institute

Not yet recruiting

3D Evaluation of the Lip Support in a Full-arch Implant-supported Rehabilitations

Prosthesis User | Occlusion | Lip | Digital Technology | Oral Soft Tissue Conditions

Portugal
University Hospital Inselspital, Berne
Baxter Healthcare Corporation

Not yet recruiting

Sensory Recovery of Digital Nerves After Microsurgical Epineural Neurorrhaphy Alone or in Combination With Tisseel - RET (RET)

Digital Nerve Injuries

Switzerland
Helsinn Healthcare SA
ICON Clinical Research

Recruiting

Study of RET Inhibitor TAS0953/HM06 in Patients With Advanced Solid Tumors With RET Gene Abnormalities ((MARGARET))

RET-altered Solid Tumors | RET-altered Non Small Cell Lung Cancer

United States, Japan
Dana-Farber Cancer Institute
Genentech, Inc.

Terminated

A Study of Alectinib in RET-rearranged Non-small Cell Lung Cancer or RET-mutated Thyroid Cancer

ALK-positive Non-small Cell Lung Cancer (NSCLC) | RET-positive Non-small Cell Lung Cancer (NSCLC) | RET-positive Thyroid Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Ofatumumab in Treating Patients With Previously Untreated Stage II, Stage III, or Stage IV Follicular Non-Hodgkin Lymphoma

Lymphoma

United States
Sofwave Medical LTD

Enrolling by invitation

Safety and Efficacy of SofWave Treatment to Lift the Upper Lip and Improve the Peri-Oral Rhytids

Wrinkle | Rhytides

United States
Eli Lilly and Company
Loxo Oncology, Inc.

Active, not recruiting

A Study of LOXO-260 in Cancer Patients With a Change in a Particular Gene (RET) That Has Not Responded to Treatment

Carcinoma, Non-Small-Cell Lung | Thyroid Neoplasms

United States
Hunan Province Tumor Hospital

Recruiting

Chemotherapy or Chemotherapy Plus PD-1 Antibody in RET Fusion Positive Advanced NSCLC Patitnts: the POSEIDON Trial (POSEIDON)

Non-small Cell Lung Cancer

China
GlaxoSmithKline

Completed

Meta-Analysis Plan for Pooled Data for Studies VRX-RET-E22-303 and VRX-RET-E22-304

Epilepsy, Partial
Chinese University of Hong Kong

Terminated

Resolution Endoclips Vs Epinephrine Injection and Heater Probe

Peptic Ulcer Hemorrhage

China
Galderma R&D

Completed

Safety and Efficacy of Lip Injections With Emervel Lips and Juvederm Ultra Smile

Local Tolerability After Lip Filler Injections

Germany
Marcelo Alberto OLIVA

Completed

Effectiveness of the Tiger Catheter on Transradial Coronariography: Randomized Compared to JudKins cathETers (TICKET)

Acute Coronary Syndrome

Argentina
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Phase Ⅰ/Ⅱ Study of the HS-10365 in Patients With Advanced Solid Tumors

Solid Tumor

China
M.D. Anderson Cancer Center

Recruiting

Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer

Recurrent Thyroid Gland Carcinoma | Poorly Differentiated Thyroid Gland Carcinoma | Thyroid Gland Anaplastic Carcinoma | Thyroid Gland Squamous Cell Carcinoma | Thyroid Gland Medullary Carcinoma | Thyroid Gland Papillary Carcinoma | Malignant Thyroid Gland Neoplasm

United States
Anagnostou, Evdokia, M.D.
Unity Health Toronto; Holland Bloorview Kids Rehabilitation Hospital; Ontario...

Unknown

A Pilot Study of an Antioxidant Cocktail vs. Placebo in the Treatment of Children and Adolescents With Rett Syndrome

Rett Syndrome

Canada
University of Idaho

Completed

Creatine Supplementation and Resistance Training in Premenopausal Females

Health Behavior

United States
Institut Cancerologie de l'Ouest

Completed

Interest of Reticulocyte Haemoglobin Content (RET-he) in Management of Functional Anemia for Patient With Solid Tumor (RET-HE)

Solid Tumor, Adult | Anemia Deficiency

France
Turning Point Therapeutics, Inc.

Terminated

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Non Small Cell Lung Cancer | Advanced Solid Tumor | Metastatic Solid Tumor | Medullary Thyroid Cancer | RET Gene Mutation

United States, Korea, Republic of

Search clinical trials for: RET-PTC4

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