Search clinical trials for: Statin therapy

Total 51739 results

Samsung Medical Center

Recruiting

Optimal Attained LDL-Cholesterol Levels in Patients Who Achieved ≥50% LDL Reduction After PCI (Lipid-PCI)

Coronary Artery Disease | Hyperlipidemias

Korea, Republic of
Xuanwu Hospital, Beijing

Not yet recruiting

Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke
The First Affiliated Hospital with Nanjing Medical...

Not yet recruiting

Extra Alirocumab in Addition to Statin Therapy in Asymptomatic Intracranial Atherosclerotic Stenosis (EAST-aICAS) (EAST-aICAS)

Stenosis | Intracranial Atherosclerosis | Atherosclerotic Plaque

China
Mayo Clinic
National Cancer Institute (NCI)

Not yet recruiting

Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Unresectable Intrahepatic Cholangiocarcinoma | Locally Advanced Intrahepatic Cholangiocarcinoma | Oligometastatic Intrahepatic Cholangiocarcinoma

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Extra Alirocumab in Addition to Statin Therapy in Symptomatic IntraCranial Atherosclerotic Stenosis ----a Pilot Study (EAST-sICAS)

Stroke | Intracranial Atherosclerotic Stenosis

China
Emory University

Recruiting

Systems Biological Assessment of Statin Effect on Vaccine Responses

Vaccine Response

United States
NewAmsterdam Pharma

Recruiting

Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies (TANDEM)

Dyslipidemias | Hypercholesterolemia | Familial Hypercholesterolemia | High Cholesterol | ASCVD

United States
Stanford University

Recruiting

Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

Inflammatory Bowel Diseases | Primary Sclerosing Cholangitis

United States
Lithuanian University of Health Sciences
Klaipėda University; Minneapolis Heart Institute; Kreiskrankenhaus Rotenburg...

Recruiting

Patient Autonomy and Statin Therapy Adherence (PASTA)

Drug Adherence

Lithuania
Samsung Medical Center

Not yet recruiting

High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium (DECISION-CAL)

Metabolic Syndrome | Dyslipidemias | Coronary Artery Calcification
Zibo Central Hospital

Recruiting

Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Adverse Effect of Cardiovascular Medications (Diagnosis)

China
Ain Shams University

Recruiting

Role of Statin Therapy in Prevention of Anthracycline-Induced Cardiotoxicity

Doxorubicin Induced Cardiomyopathy

Egypt
Wuhan Union Hospital, China
Peking University First Hospital

Recruiting

High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program

Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus, Type 2

China
Yonsei University

Recruiting

Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial

Coronary Artery Disease Requiring Coronary Revascularization With Newer Generation DES Implantation

Korea, Republic of
University Hospital, Essen

Recruiting

Improving Adherence to Statin Therapy Through a Medication Management Application (STAPP)

Atherosclerosis

Germany
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Evolocumab Added to Statin Therapy in Symptomatic Intracranial Atherosclerotic Stenosis (EAST-ICAS) (EAST-ICAS)

Stroke Patients With Symptomatic Intracranial Atherosclerotic Stenosis

China
Second Affiliated Hospital, School of Medicine,...
Fudan University; Peking Union Medical College Hospital; West China Hospital; The... and other collaborators

Recruiting

Platform Adaptive Embedded Trial for Acute Respiratory Distress Syndrome (PETARDS)

Acute Respiratory Distress Syndrome

China
Sichuan Provincial People's Hospital
Science & Technology Department of Sichuan Province

Not yet recruiting

Intracranial Hemorrhage Risk of Intensive Statin in Acute Ischemic Stroke With Cerebral Microbleeds

Acute Ischemic Stroke | Cerebral Microbleeds

China
Seung-Whan Lee, M.D., Ph.D.
Yuhan Corporation

Recruiting

Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus (PROVE-DM)

Pre Diabetes | ASCVD

Korea, Republic of
National Medical Research Center for Therapy and...

Recruiting

Efficacy and Safety of Pitavastatin and PCSK9 Inhibitors in Liver Transplant Patients (PINTL)

Dyslipidemias | Hyperlipidemias | Liver Transplant Disorder | Immunosuppression | Hydroxymethylglutaryl-CoA Reductase Inhibitors | Statins

Russian Federation
University of Texas Southwestern Medical Center

Recruiting

Polypill in Acute Coronary Syndrome (POLY-ACS)

Coronary Artery Disease | Acute Coronary Syndrome | Lipid Disorder

United States
Nanjing First Hospital, Nanjing Medical University
National Natural Science Foundation of China; Nanjing Medical University

Recruiting

PCSK 9 Inhibitor Added to High-Intensity Statin Therapy to Prevent Cardiovascular Events in Patients With ACS After PCI (SHAWN)

Hyperlipidemias | Acute Coronary Syndrome | Percutaneous Coronary Intervention | Cardiovascular Events

China
University of Edinburgh
Chief Scientist Office of the Scottish Government

Recruiting

Targeting Investigation and Treatment in Patients With Type 2 Myocardial Infarction (TARGET-Type 2)

Myocardial Infarction Type 2

United Kingdom
Novartis Pharmaceuticals

Recruiting

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (V-PLAQUE)

Coronary Artery Disease

United States, Italy, Spain, France, Korea, Republic of, Hungary, Japan, Argentina, China, India, Belgium, Switzerland, United Kingdom, Canada, Australia, Brazil, Chile, Ireland
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Vascular Endothelial Dysfunction in Sleep Apnea

Obstructive Sleep Apnea of Adult

United States
Chinese Academy of Medical Sciences, Fuwai Hospital

Not yet recruiting

A Study for Exploring the Efficacy of Naoxintong Capsules in the Treatment of Coronary Atherosclerotic Plaque on the Basis of Optimal Medical Therapy (Aspirin,Statins,Clopidogrel, Etc.): Stage One (NXT-ASSESS)

Atherosclerotic Cardiovascular Disease

China
University Clinical Centre of Republic of Srpska

Recruiting

Low-density Lipoprotein Cholesterol Reduction With State-of-the-art Therapy in Secondary Prevention and Major Cardiovascular Adverse Events: Republic of Srpska Registry (RS-ACS)

Dyslipidemias | Acute Coronary Syndrome

Bosnia and Herzegovina
Odense University Hospital
Odense Patient Data Explorative Network; GCP-unit at Odense University Hospital

Recruiting

Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement (STARC)

Postoperative Atrial Fibrillation

Denmark
Tongji Hospital

Recruiting

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Ischemic Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis)

China
Chang Gung Memorial Hospital

Recruiting

Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease (SATBRAD)

Dual Antiplatelet Therapy | Acute Stroke | Statin

Taiwan
Massachusetts Eye and Ear Infirmary

Recruiting

Dark Adaptation as an Early Indicator of Response to Statin Therapy for Intermediate AMD (DELPHI)

Age-related Macular Degeneration

United States
Yonsei University

Recruiting

Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial

Atherosclerotic Cardiovascular Disease

Korea, Republic of
Aarhus University Hospital
Odense University Hospital; Rigshospitalet, Denmark; University of Copenhagen; Herning... and other collaborators

Recruiting

The MASTER Study (MAmmary Cancer STatin ER Positive Study)

Breast Cancer Female | Estrogen Receptor Positive Tumor

Denmark
Bobbie Jo Rimel, MD

Recruiting

Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer

Recurrent Ovarian Cancer | Platinum-sensitive Ovarian Cancer

United States
Tianjin Chest Hospital

Recruiting

Effect of Evolocumab Added to Moderate-Intensity Statin Therapy on LDL-C Lowering and Cardiovascular Adverse Events in Patients With Acute Coronary Syndrome (EMSIACS)

Acute Coronary Syndrome | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor

China
Centro Cardiopatici Toscani
Azienda USL 4 Prato

Recruiting

Protective Effect of Early High Dose stATins On Cardiovascular and Renal Events in Acute Coronary Syndrome (PRATO-ACS)

Acute Coronary Syndrome

Italy
Kobe University

Recruiting

To Evaluate the Efficacy of Alirocumab for Neoatherosclerosis by Using OCT, in Comparison With Standard Statin Therapy (POLARIS)

Coronary Artery Disease Progression

Japan
McMaster University
Canadian Cancer Society (CCS); Prostate Cancer Canada

Recruiting

A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (RADICALPC)

Cardiovascular Disease | Prostate Cancer

United States, Canada, Australia, Brazil, Israel, Turkey, Colombia
Wenzhou Medical University

Recruiting

The Efficacy and Safety of Combined Therapy With Red Yeast Rice and Low-dose Statin：Comparing With Standardized Statin

Atherosclerosis | Dyslipidemia

China
University Hospital Goettingen
Society for Pediatric Nephrology (Germany); Deutsche Gesellschaft für Nephrologie and other collaborators

Recruiting

European Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

Pediatric Kidney Disease | Alport Syndrome | Hereditary Kidney Disease | Thin Basement Membrane Disease | Familial Benign Hematuria

Germany
University of Colorado, Denver

Active, not recruiting

Statin Therapy in Patients With Early Stage ADPKD

Autosomal Dominant Polycystic Kidney | ADPKD

United States
Hospital de Granollers
Department of Health, Generalitat de Catalunya

Completed

Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients (HGG_UCI1)

Sepsis | Septic Shock

Spain
Ludwig Institute for Cancer Research
AstraZeneca

Completed

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Esophageal Cancer

United Kingdom
GWT-TUD GmbH

Active, not recruiting

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry (PERI-DYS)

Dyslipoproteinemias

Germany
Istituto Auxologico Italiano
European Society of Hypertension; Chinese Hypertension League

Completed

Optimal Blood Pressure and Cholesterol Targets for Preventing Recurrent Stroke in Hypertensives (ESH-CHL-SHOT)

Stroke | Hypertension | Transient Ischemic Attack

Russian Federation
Vanderbilt University Medical Center

Completed

Best Practice Advisory to Initiate High-Intensity Statin Therapy in Patients With Peripheral Artery Disease

Peripheral Artery Disease

United States
Aligos Therapeutics

Active, not recruiting

A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)

Healthy Volunteers

United States
Novartis Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE) (V-INITIATE)

Atherosclerotic Cardiovascular Disease

United States
University of Kansas Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Impact of Statin Therapy on Muscle Mitochondrial Function and Aerobic Capacity

Mitochondrial Diseases

United States
University of Kansas Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Active, not recruiting

Impact of Statin Therapy on Adaptations to Aerobic Exercise

Cardiovascular Diseases

United States

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