Search clinical trials for: TQT TTX Halneuron cardiac safety

Total 74055 results

Wex Pharmaceuticals Inc.
Celerion

Completed

A Phase 1, Single Ascending Dose, Randomized, Double-Blind, Placebo and Positive Controlled Study to Evaluate the Cardiovascular Effect of Tetrodotoxin in Healthy Adult Subjects

TQT Study

United States
Wex Pharmaceuticals Inc.

Recruiting

A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain

Chemotherapy-induced Peripheral Neuropathy | Chemotherapy-induced Neuropathic Pain

United States
Mylan Inc.
Theravance Biopharma

Completed

Thorough QT (TQT) Study of TD-4208 in Healthy Subjects

Cardiac Repolarization in Healthy Subjects

United States
Akebia Therapeutics

Completed

Effect of AKB-6548 on Cardiac Repolarization Intervals in Healthy Volunteers

Healthy Volunteers

United States
Pediatric Clinical Research Platform
University Hospital, Geneva

Not yet recruiting

Performance and Safety of the Pneumoscope Device in Adults and Children

Pneumonia | Asthma | Respiratory Diseases | Cyanotic Heart Disease

Switzerland
Aktiia SA

Not yet recruiting

Evaluation of the Performance and Safety of the Aktiia Spot-check Optical Blood Pressure Monitoring (OBPM) Device at Fingertip (Aktiia G2C) Against Double Auscultation, and Comparison With Oscillometry and Aktiia Bracelet G2: a Single-center Prospective Clinical Study

Hypertension

Switzerland
The People's Hospital of Gaozhou

Recruiting

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

The Efficacy and Safety of Dapagliflozin in Improving Heart Failure in Dialysis Patients

China
Medical University of Vienna
Ludwig Boltzmann Institute Digital Health and Patient Safety

Recruiting

Tele-Support for Emergency Medical Technicians (POHCA)

Cardiac Arrest

Austria
Starmed
Helptrial

Not yet recruiting

To Compare and Evaluate the Efficacy and Safety Between TS-RF System and BRK Transseptal Needles Used for Transseptal Puncture for Left Atrial Access.

Heart Diseases | Atrial Fibrillation | Arrhythmias, Cardiac
Tang Ziren

Not yet recruiting

Butylphthalide's Safety and Efficacy for Improving Neurological Function Prognosis in Patients With Cardiac Arrest (BNCA Trial)

Cardiac Arrest | Butylphthalide | Neuroprotective Drugs

China
Angiowave Imaging

Not yet recruiting

Clinical Evaluation of Radiation Reduction for Optimized Safety (CERROS)

Myocardial Infarction | Coronary Artery Disease | Coronary Disease | Chest Pain | Angina Pectoris | Coronary Stenosis

United States
BrosMed Medical Co., Ltd
Chinese Academy of Medical Sciences, Fuwai Hospital

Not yet recruiting

Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for Coronary Small Vessels

Coronary Artery Disease
Oxford University Hospitals NHS Trust
Edwards Lifesciences

Recruiting

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety (EARLY-Edge)

Heart Failure | Mitral Regurgitation | Tricuspid Regurgitation | Mitral Repair

United Kingdom
Heart Rhythm Clinical and Research Solutions, LLC
Boston Scientific Corporation

Not yet recruiting

A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF (DISRUPT-AF)

Atrial Fibrillation

United States
Heart Rhythm Clinical and Research Solutions, LLC
Biosense Webster, Inc.

Recruiting

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation. (QDOT PAS)

Paroxysmal Atrial Fibrillation

United States
Bark Technology LLP

Recruiting

Evaluation of the Effectiveness and Safety of Vibro-acoustic Pulmonary Therapy (VAPT) in Complex Therapy for Acute Respiratory Failure of Mixed Type I-II Stages in Comparison With Percussion Massage in Cardiac Surgical Patients in the Early Postoperative Period

Cardiac Surgical Patients (CABG,Mammary Coronary Bypass Surgery,Plastic and Replacement of Valves, Atrial Septal Defect,Ventricular Septal Defect)

Kazakhstan
Johns Hopkins University

Not yet recruiting

Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial

Myocardial Stunning

United States
JW Medical Systems Ltd

Not yet recruiting

Effectiveness and Safety of Coronary Scoring Balloon Dilation Catheter in the Pretreatment of Coronary Stenosis Lesions

Coronary Artery Disease
Eli Lilly and Company

Recruiting

A Study to Investigate the Effect of Lepodisiran on the Reduction of Major Adverse Cardiovascular Events in Adults With Elevated Lipoprotein(a) - ACCLAIM-Lp(a)

Elevated Lp(a) | Atherosclerotic Cardiovascular Disease (ASCVD)

United States, Taiwan, Canada, Argentina, China, Japan, Denmark, Australia, Brazil, Hungary, Mexico, Germany, Romania, Korea, Republic of, United Kingdom, Belgium, Czechia, India, Netherlands, Poland, Slovakia, France, Spain, Austria, Puerto...
Regional Cardiology Center, The Copper Health Centre...

Recruiting

Lower Silesia Sinus Reducer Registry (LSSRR)

Safety Issues | Efficacy, Self

Poland
Beijing Suncadia Pharmaceuticals Co., Ltd

Not yet recruiting

Study on the Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-2004 Injection in Adult Patients With Atrial Fibrillation

Atrial Fibrillation
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Respiratory Distress Syndrome After Cardiac Surgery :a Single Centre Random Control Trial.

Cardiac Disease
Pacira Pharmaceuticals, Inc

Not yet recruiting

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery

Postoperative Pain
River 2 Renal Corp.
International HealthCare, LLC

Not yet recruiting

To Evaluate the Safety, Tolerability and Efficacy of R2R01 Combined With SOC as Compared to SOC Alone in Outpatients With Worsening Heart Failure (WHF)

Heart Failure | Worsening Heart Failure (WHF)

United States
Xijing Hospital

Recruiting

Safety and Efficacy of Post-marketing Transcatheter Aortic Valves in "Real World" Chinese Patients

Aortic Valve Disease Mixed

China
SHINKEI Therapeutics, Inc
Duke Clinical Research Institute

Not yet recruiting

Study to Assess the Safety of Amantadine Hydrochloride (HCl) Intravenous (IV) Solution (MR-301) in Patients With Severe Traumatic Brain Injury (TBI).

Traumatic Brain Injury
Medical University of Vienna
Ludwig Boltzmann Institute Digital Health and Patient Safety; Emergency Medical...

Recruiting

Feasibility of Doppler Ultrasound for Pulse Detection in Out-of-Hospital Cardiac Arrest Patients

Cardiac Arrest, Out-Of-Hospital

Austria
Tenaya Therapeutics
Johns Hopkins University; Mayo Clinic

Recruiting

Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC (RIDGE-1)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States
Cardurion Pharmaceuticals, Inc.

Recruiting

Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Preserved Ejection Fraction (Cycle-2-PEF) (Cycle-2-PEF)

Heart Diseases | Cardiovascular Diseases | Heart Failure | Heart Failure Preserved Ejection Fraction

United States
Cardurion Pharmaceuticals, Inc.

Recruiting

A Study to Assess Safety & Effectiveness of Tovinontrine in Chronic Heart Failure With Reduced Ejection Fraction (Cycle-1-REF) (Cycle-1-REF)

Heart Diseases | Cardiovascular Diseases | Heart Failure | Heart Failure With Reduced Ejection Fraction

United States
Yi Han
Qianfoshan Hospital

Recruiting

Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

Heart Failure | Efficacy | Safety | Levosimendan | Milrinone

China
Boehringer Ingelheim

Recruiting

A Study to Test Whether Multiple Doses of BI 456906 Have an Effect on Cardiac Safety in People With Overweight or Obesity

Obesity | Overweight

Germany
Chelyabinsk Regional Clinical Hospital

Recruiting

Early Safety and Clinical Efficacy of Mitral Allograft in Tricuspid Surgery (ESEMATS)

Tricuspid Valve Insufficiency | Allografts

Russian Federation
AstraZeneca

Recruiting

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Transthyretin Amyloid Cardiomyopathy

China
Mirum Pharmaceuticals, Inc.

Recruiting

Long-Term Safety and Clinical Outcomes of Livmarli in Patients With Alagille Syndrome (LEAP) (LEAP)

Alagille Syndrome

United States
Korea University Anam Hospital

Recruiting

Clinical Trial to Evaluate Efficacy and Safety of Rivaroxaban 15mg and 20mg in Patients With Non-valvular Atrial Fibrillation (REVISE-AF)

Atrial Fibrillation | Anticoagulant Adverse Reaction

Korea, Republic of
Genoss Co., Ltd.

Recruiting

Safety and Effectiveness of GENOSS DES in Patients With Multivessel Coronary Artery Disease (GENOSS-MV)

Percutaneous Coronary Intervention | Multivessel Coronary Artery Disease

Korea, Republic of
Second Xiangya Hospital of Central South University

Recruiting

Safety and Efficacy of Stereotactic Body Radiotherapy in the Treatment of Hypertrophic Obstructive Cardiomyopathy (SAFECARE)

Hypertrophic Obstructive Cardiomyopathy | Stereotactic Body Radiotherapy

China
Edwards Lifesciences

Not yet recruiting

ALLIANCE Mitral: Safety and Effectiveness of SAPIEN X4 Transcatheter Heart Valve - Mitral

Mitral Regurgitation | Mitral Valve Disease | Mitral Stenosis
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
Ever Supreme Bio Technology Co., Ltd.

Recruiting

Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells as an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients

ST Elevation Myocardial Infarction

Taiwan
Bristol-Myers Squibb

Not yet recruiting

A Study to Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy

Korea, Republic of
Pan Xiangbin

Recruiting

A Prospective, Multicenter, Single-arm Study to Evaluate a Transcatheter Aortic Valve System Safety and Efficacy for the Treatment of Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

China
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
Bristol-Myers Squibb

Recruiting

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) (AURORA-HFpEF)

Heart Failure

United States, Canada, Italy, Poland, Spain
The Affiliated Hospital of Xuzhou Medical University
RainMed Medical

Recruiting

Clinical Trial for Evaluating the Effectiveness and Safety of Online caIMR in STEMI Patients (FlashIV)

STEMI | Microvascular Coronary Artery Disease

China
PT Bio Farma

Recruiting

Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial

Safety Issues | Effect of Drug

Indonesia
Seoul National University Hospital

Recruiting

Safety and Efficacy of Paclitaxel Coated PTCA Balloon Catheter With a Shellac Plus Vitamin E Excipient (GENOSS® DCB) in Patients With Coronary In-stent Restenosis (ISR): A Prospective, Multi-center, Observational Study (SFRGENISTA)

Coronary Artery Disease | In-stent Restenosis

Korea, Republic of
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Effectiveness of TaurusTrio™ Heart Valve System in Patients With Severe Aortic Regurgitation (AR)

Aortic Regurgitation

China
Pacertool AS

Not yet recruiting

Pacertool Early Feasibility Study - Safety and Performance

Heart Failure With Reduced Ejection Fraction | Dyssynchrony | Medical Device Performance

Georgia

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