Search clinical trials for: Therapeutic Uses

Total 12355 results

National Cancer Institute (NCI)

Recruiting

Eltanexor (KPT-8602) With Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic Syndromes

Myelodysplastic Syndromes

United States
North Florida Foundation for Research and Education
University of Florida; Brooks Rehabilitation; North Florida/South Georgia Veterans...

Recruiting

Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

Central Nervous System Diseases | Nervous System Diseases | Wounds and Injuries | Endocrine System Diseases | Gonadal Disorders | Trauma, Nervous System | Spinal Cord Diseases | Hypogonadism | Spinal Cord Injuries | Gait Disorders, Neurologic | Spinal Cord Injury | Wounds and Injury | Testosterone Deficiency | Hormone... and other conditions

United States
University of Minnesota
Minneapolis Veterans Affairs Medical Center

Recruiting

Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans

Major Depressive Disorder | Post-Traumatic Stress Disorders

United States
Knight Therapeutics (USA) Inc

Recruiting

Treatment of Leishmaniasis With Impavido® (Miltefosine): Pregnancy Registry

Leishmaniasis or Other Uses of Miltefosine

United States
Emergent BioSolutions
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Safety and Pharmacokinetics of UV-4B Solution Administered Orally as Multiple Ascending Doses to Healthy Subjects

Viral Infection

United States
Emergent BioSolutions
Quintiles, Inc.; Unither Virology

Completed

Study to Determine the Safety, Tolerability and Pharmacokinetics of UV-4B Solution Administered Orally in Healthy Subjects (UV)

Viral Infection

United States
STCube, Inc.

Completed

A Study of hSTC810 With Advanced/Metastatic Solid Tumors (STCUBE-001)

Advanced Solid Tumor

United States, Korea, Republic of
University of Pennsylvania

Active, not recruiting

Abatacept for the Treatment of Giant Cell Arteritis

Giant Cell Arteritis

United States, Canada
InDex Pharmaceuticals

Terminated

The Efficacy and Safety of Cobitolimod in Participants With Moderate to Severe Active Left-Sided Ulcerative Colitis (CONCLUDE)

Ulcerative Colitis

Korea, Republic of, United Kingdom, United States, Mexico, Belgium, Netherlands, Denmark, Poland, Israel, Germany, France, Australia, Austria, Canada, Lithuania, Croatia, Italy, Romania, Turkey, Portugal, Slovakia, Hungary, Norway, Bosnia... and more
VA Office of Research and Development
University of Florida

Terminated

Testosterone Plus Finasteride Treatment After Spinal Cord Injury

Central Nervous System Diseases | Nervous System Diseases | Wounds and Injuries | Endocrine System Diseases | Gonadal Disorders | Trauma, Nervous System | Spinal Cord Diseases | Hypogonadism | Spinal Cord Injuries | Spinal Cord Injury | Genital Diseases, Male

United States
Neuroscience Trials Australia
The Florey Institute of Neuroscience and Mental Health

Completed

STOP-MSU: Stopping Haemorrhage With Tranexamic Acid for Hyperacute Onset Presentation Including Mobile Stroke Units

Intracerebral Haemorrhage

Australia, Finland, Taiwan, New Zealand, Vietnam
University of South Florida
Bristol-Myers Squibb; University of Pennsylvania; National Institute of Arthritis... and other collaborators

Active, not recruiting

Abatacept for the Treatment of Relapsing, Non-Severe, Granulomatosis With Polyangiitis (Wegener's)

Wegener's Granulomatosis | Granulomatosis With Polyangiitis | ANCA-Associated Vasculitis | Granulomatosis With Polyangiitis (Wegener's)

United States, United Kingdom, Ireland, Canada, Germany
University of Chicago

Completed

The Effect of Loop Diuretics on Severity and Outcome of Acute Kidney Injury

Acute Kidney Failure

United States
VA Office of Research and Development

Completed

Coenzyme Q10 Phase III Trial in Gulf War Illness

Gulf War Illness | Chronic Fatigue | Coenzyme Q10 | Ubiquinol

United States
University of South Florida
National Heart, Lung, and Blood Institute (NHLBI); National Institute of Arthritis... and other collaborators

Active, not recruiting

The Assessment of Prednisone In Remission Trial (TAPIR) - Patient Centric Approach (TAPIR)

Vasculitis | Granulomatosis With Polyangiitis | Wegener Granulomatosis

United States
InDex Pharmaceuticals

Completed

The Efficacy and Safety of Cobitolimod (Kappaproct®) in Chronic Active Treatment Refractory Ulcerative Colitis Patients (COLLECT)

Colitis, Ulcerative

Czechia, France, Germany, Hungary, Italy, Poland, United Kingdom
Mylan Inc.

Completed

Special Investigation of LipaCreon on Long-term Use in Patients With Pancreatic Exocrine Insufficiency

Digestive System Diseases | Pancreatic Diseases | Exocrine Pancreatic Insufficiency

Japan
Mylan Inc.

Completed

Special Investigation (All Cases) of LipaCreon in Patients With Pancreatic Exocrine Insufficiency Due to Cystic Fibrosis

Digestive System Diseases | Pancreatic Diseases | Cystic Fibrosis | Exocrine Pancreatic Insufficiency

Japan
Hospital for Special Surgery, New York

Completed

Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty

Total Knee Arthroplasty

United States
Hospital for Special Surgery, New York

Completed

Pregabalin for the Treatment of Pain After Posterior Spinal Fusions

Lumbar Spinal Fusions

United States
Washington University School of Medicine
Centers for Disease Control and Prevention

Completed

Probiotics to Promote Intestinal Health

Communicable Diseases | Infection | Therapeutic Uses | Anti-Infective Agents | Pharmacologic Actions

United States
Albert Einstein College of Medicine

Completed

Effect of Resveratrol on Age-related Insulin Resistance and Inflammation in Humans

Type 2 Diabetes Mellitus | Insulin Resistance

United States
BeiGene

Completed

BGB 3111 in Combination With Obinutuzumab in Participants With B-Cell Lymphoid Malignancies

B-cell Lymphoid Malignancies

Australia, Korea, Republic of, United States
Asker & Baerum Hospital
Vestre Viken Hospital Trust; Helse Sor-Ost

Completed

Rate Control in Atrial Fibrillation II (RATAFII)

Atrial Fibrillation | Permanent Atrial Fibrillation

Norway
Cedars-Sinai Medical Center

Completed

Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma

Glioma | Glioblastoma | Astrocytoma | Brain Tumor | Glioblastoma Multiforme

United States
Bayer
Janssen Research & Development, LLC

Completed

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Germany)

Venous Thrombosis | Atrial Fibrillation | Acute Coronary Syndrome | Pulmonary Embolism

Germany
Bayer
Janssen Scientific Affairs, LLC

Completed

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)

Venous Thrombosis | Atrial Fibrillation | Acute Coronary Syndrome | Pulmonary Embolism

Netherlands
Bayer
Janssen Scientific Affairs, LLC

Completed

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)

Venous Thrombosis | Atrial Fibrillation | Acute Coronary Syndrome | Pulmonary Embolism

Sweden
Bayer
Janssen Research & Development, LLC

Completed

Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (UK)

Venous Thrombosis | Atrial Fibrillation | Acute Coronary Syndrome | Pulmonary Embolism

United Kingdom
University of California, San Diego

Completed

Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.

Schizophrenia

United States
VA Office of Research and Development

Completed

CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial (VAKCCT)

Skin Diseases | Carcinoma | Carcinoma, Squamous Cell | Carcinoma, Basal Cell | Neoplasms, Squamous Cell | Skin Neoplasms | Neoplasms, Basal Cell

United States
Shire

Completed

Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers

Hereditary Angioedema (HAE)

United States
Pfizer

Completed

A Multicenter Phase 3, Open-Label Study of Bosutinib Versus Imatinib in Adult Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

Leukemia, Myelogenous, Chronic, Breakpoint Cluster Region-Abelson Proto-oncogene (BCR-ABL) Positive

France, United States, Canada, Spain, Czechia, Singapore, Thailand, Denmark, Norway, Korea, Republic of, Finland, Hungary, Sweden, Netherlands, Italy, Germany, Ukraine, South Africa, Taiwan, Australia, Belgium, Israel, Mexico, Poland, S... and more
Merck Sharp & Dohme LLC

Completed

Study of Vorinostat (MK-0683) or Placebo, in Combination With Bortezomib in Participants With Multiple Myeloma (MK-0683-088 AMN)

Multiple Myeloma
Incyte Corporation

Completed

Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL)

MPN (Myeloproliferative Neoplasms)

United States, Puerto Rico
InDex Pharmaceuticals

Completed

The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis (CONDUCT)

Ulcerative Colitis

Hungary, Czechia, France, Germany, Poland, Russian Federation, Serbia, Spain, Sweden, Ukraine
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

An Open-Label Long-Term Study Of Pregabalin For The Treatment Of Central Neuropathic Pain

Pain | Neuralgia | Spinal Cord Diseases | Spinal Cord Injuries

Japan
TSI, LLC

Terminated

Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor

Acute Ischemic Stroke

Netherlands
Novartis Pharmaceuticals

Terminated

Safety and Efficacy of QAX576 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis

United States, United Kingdom
University of Texas Southwestern Medical Center
Astellas Pharma US, Inc.

Completed

Drug Concentration Analysis of Micafungin in Overweight, Obese, and Extremely Obese Volunteers (Micafungin)

Obesity | Nutrition Disorders | Overweight

United States
Weill Medical College of Cornell University
National Institute of Mental Health (NIMH)

Completed

Emotional and Cognitive Control in Late-Onset Depression

Depression

United States
Isofol Medical AB

Completed

PK/PD Investigation of Modufolin (Arfolitixorin) in Plasma, Tumor and Adjacent Mucosa Adjacent Mucosa in Patients With Colon Cancer

Colonic Neoplasms

Sweden
Gilead Sciences

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Voxilaprevir in Adults With Chronic Hepatitis C Virus Infection

Hepatitis C Virus Infection

United States, Puerto Rico
Isofol Medical AB

Completed

Modufolin (Arfolitixorin) in Combination With 5-Fluorouracil Alone or Together With Oxaliplatin or Irinotecan in Colorectal Cancer

Colorectal Neoplasm

Denmark, Norway, Greece, Sweden
Isofol Medical AB

Completed

An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer

Rectal Cancer

Sweden
Zosano Pharma Corporation

Completed

A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine (ADAM)

Migraine

United States
Binghe Xu
Hoffmann-La Roche

Unknown

Capecitabine Maintenance Therapy Following Capecitabine Combined With Docetaxel in Treatment of mBC (CAMELLIA)

Skin Diseases | Neoplasms by Site | Breast Neoplasms | Breast Diseases | Neoplasm Metastasis

China
Thomas Jefferson University

Terminated

Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA

Stage IV Colorectal Cancer

United States
Boston Children's Hospital
Terrana ITP Research Fund

Completed

ICON1: Treatment Decisions and Outcomes in Pediatric Refractory ITP (ICON1)

Immune Thrombocytopenia

United States, Canada
Yale University

Completed

Attention Training for Opioid-maintained Cocaine Users

Addiction | Opiates | Methadone | Cocaine

United States

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