Search clinical trials for: Thrombopoietin receptor agonist

Total 25693 results

Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura

China
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia (AIHA ITP CIN)

Myelodysplastic Syndromes | Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Cold Agglutinin Disease | Autoimmune Neutropenia | Chronic Idiopathic Neutropenia

Italy
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine for Poor Graft Function Post Allo-HSCT

Poor Graft Function
Assiut University

Not yet recruiting

Safety of Oral Thrombopoietin Receptor Agonist in Pediatric Chronic ITP

Thrombopoietin Receptor Agonist
Hanny Al-Samkari, MD
Swedish Orphan Biovitrum

Recruiting

Avatrombopag vs. Placebo for CIT in GI Malignancies (ACT-GI)

Gastrointestinal Neoplasms | Gastrointestinal Cancer | Chemotherapy-Induced Thrombocytopenia

United States
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine and Umbilical Cord Blood for Poor Graft Function Post Allo-HSCT

Poor Graft Function
Peking University People's Hospital
Qilu Hospital of Shandong University; Beijing Tongren Hospital; Beijing Hospital and other collaborators

Not yet recruiting

Zanubrutinib and Eltrombopag as Second-line Treatment in Adults With Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China
AO GENERIUM

Completed

Comparative Study of Clinical Efficacy and Safety of GNR-069 and Nplate in Patients With ITP

Idiopathic Thrombocytopenic Purpura

Russian Federation
AO GENERIUM

Enrolling by invitation

Study of the Safety and Immunogenicity of Long-term GNR-069 Therapy in ITP Patients

Idiopathic Thrombocytopenic Purpura

Russian Federation
Swedish Orphan Biovitrum

Active, not recruiting

An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP (ADOPT)

Immune Thrombocytopenia | ITP

Croatia, Czechia, Germany, Italy, Netherlands, Norway, Spain, Switzerland, United Kingdom
Novartis Pharmaceuticals

Completed

A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP (XPAG-ITP)

Immune Thrombocytopenia (ITP)

Germany
University Children's Hospital Basel
Novartis Pharmaceuticals; Stiftung zur Förderung medizinischer und biologischer... and other collaborators

Active, not recruiting

Immunomodulation With Eltrombopag in ITP (iROM2)

Primary Immune Thrombocytopenia (ITP)

Switzerland
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Thrombocytopenia

United States
M.D. Anderson Cancer Center
GlaxoSmithKline

Completed

Phase II Eltrombopag in Chronic Lymphocytic Leukemia (CLL)

Leukemia | CLL

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients

Thrombocytopenia | Anemia, Aplastic | Anemia, Hypoplastic

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Rate of Prolonged Response After Stopping Thrombopoietin-receptor Agonists Treatment in ITP (STOP-AGO)

Persistent or Chronic ITP

France
Novartis Pharmaceuticals

Completed

A Safety and Efficacy Study of Eltrombopag in Subjects With AML

Acute Leukaemia

United States, Belgium, Canada, Australia, Greece, Israel, Russian Federation, Hungary, Korea, Republic of, Poland
Novartis Pharmaceuticals

Completed

A Long-term Safety Study of Eltrombopag in Pediatric Patients With Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopenic, Idiopathic

Russian Federation
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

Response Rate and Duration After Discontinuation Thrombopoietin Receptor Agonists Primary Immune Thrombocytopenia

Immune Thrombocytopenia

Italy
GlaxoSmithKline

Completed

Clinical Evaluation of Eltrombopag in Chronic Idiopathic Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopenic, Idiopathic | Idiopathic Thrombocytopenic Purpura

Japan
GlaxoSmithKline

Completed

Eltrombopag Treatment of Thrombocytopenia in Subjects With Advanced Myelodysplastic Syndrome (MDS) or Secondary Acute Myeloid Leukemia After MDS (sAML/MDS)

Myelodysplastic Syndrome

Puerto Rico, United States, Taiwan, Germany, Denmark, Hong Kong, Korea, Republic of, France, United Kingdom, Italy, Brazil
GlaxoSmithKline

Completed

SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adult Cancer Patients Receiving Chemotherapy

Thrombocytopaenia

Spain, Taiwan, Bulgaria, United States, Argentina, Russian Federation, Germany, Korea, Republic of, Austria, India, Italy, United Kingdom, Poland, Romania, Ukraine, Hungary, Peru, Czech Republic, Mexico
GlaxoSmithKline

Completed

LENS - Long-term Eltrombopag Observational Study (LENS)

Purpura, Thrombocytopaenic, Idiopathic

United States, Bulgaria, Italy, Peru, Russian Federation, Canada, France, Germany, Hong Kong, Spain, Sweden, United Kingdom, Hungary, Poland, Ukraine, Czech Republic, India, Australia, Tunisia, Puerto Rico, Pakistan
Weifeng Tu

Unknown

Effect of Dexmedetomidine for Postoperative Intravenous Patient Controlled Analgesia

Patient-Controlled Analgesia

China
GlaxoSmithKline

Completed

A Longitudinal 2-year Bone Marrow Study of Eltrombopag in Previously Treated Adults, With Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopaenic, Idiopathic

Italy, Germany, Hong Kong, Korea, Republic of, United States, Pakistan, Russian Federation, India, Czech Republic, Hungary, France
Nordic MDS Group
GlaxoSmithKline

Completed

Safety Study of Eltrombopag Combined With Azacitidine to Treat Myelodysplastic Syndrome (MDS) (NMDSG10A)

Thrombocytopenia | Myelodysplastic Syndrome

Sweden
GlaxoSmithKline

Completed

SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Refractory Immune Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopaenic, Idiopathic

Thailand, Korea, Republic of, United Kingdom, New Zealand, Germany, Greece, Hong Kong, Pakistan, Poland, Romania, Russian Federation, Slovenia, Taiwan
Henri Mondor University Hospital
Paris 12 Val de Marne University

Completed

Eltrombopag and Romiplostim Used Alternatively in Patients With Immune Thrombopenia (ITP): Efficacy and Safety.

Immune Thrombocytopenia | Thrombopoietin Receptor Agonist
GlaxoSmithKline

Completed

SB497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Thrombocytopenia Due To Hepatitis C

Hepatitis C | Hepatitis C, Chronic | Thrombocytopenia

United States, Germany, France, Puerto Rico, United Kingdom
Catharina Ziekenhuis Eindhoven
Maastricht University

Not yet recruiting

The Contractile Response of the Thoracic Aorta to Vasoactive Substances (AorticContract)

To Establish and Quantify the in Vivo Contractility of the Human Thoracic Aorta

Netherlands
Ali Aminian

Not yet recruiting

Fibrosis Lessens After Metabolic Surgery (FLAMES)

Obesity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) | Metabolic Dysfunction-Associated Steatohepatitis (MASH)

United States, Sweden, Ireland, Finland, United Kingdom, Spain, Switzerland, Brazil, Canada, Italy, Kuwait, India, Mexico
Steen Hvitfeldt Poulsen

Recruiting

Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy (DobAttrAS)

Aortic Stenosis | Transthyretin Amyloid Cardiomyopathy

Denmark
State University of New York - Upstate Medical...

Not yet recruiting

Intranasal Dexmedetomidine vs. Standard of Care for Emergency Department (ED) Procedural Sedation in the Older Adult

Altered Mental Status
Dr Abdurrahman Yurtaslan Ankara Oncology Training...

Not yet recruiting

The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block (TAP)

Colorectal Neoplasms | Colorectal Cancer

Turkey
AstraZeneca

Not yet recruiting

Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD (COnCORD)

Chronic Obstructive Pulmonary Disease (COPD)
Tribhuvan University Teaching Hospital, Institute...

Not yet recruiting

Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia

Visceral Pain
Beni-Suef University

Recruiting

The Sedative Effects of Dexmedetomidine VS Propofol During Peribulbar Anesthesia in Patients Undergoing Vitrectomy Surgery

Satisfaction | Patient

Egypt
CT Glaucoma Associates

Recruiting

How Much Does Reduced Dosing of Latanoprost and Dorzolamide-timolol Affect Pressure?

Glaucoma, Open-Angle | Glaucoma; Drugs

United States
Minia University Hospital

Recruiting

Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein.

Cognitive Impairment

Egypt
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
National Cancer Institute (NCI)

Not yet recruiting

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Chronic Lymphocytic Leukemia (CLL)

Leukemia, Lymphocytic, Chronic, B-Cell | B-Cell Chronic Lymphocytic Leukemia | B-Lymphocytic Leukemia, Chronic

United States
Capital Medical University

Not yet recruiting

Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment

Idiopathic Intracranial Hypertension
University of Oxford
NIHR Oxford Health Biomedical Research Centre

Not yet recruiting

Semaglutide and Cognition in Healthy Volunteers (OxSENSE)

Cognitive Change

United Kingdom
Tanta University

Not yet recruiting

Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy

Dexmedetomidine | Splenectomy | External Oblique Intercostal Plane Block

Egypt
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery

Delirium, Postoperative
Northwestern University

Not yet recruiting

Anxiety Lowering and Deprescribing Through Emotion Regulation (ALDER)

Anxiety Disorders | Sleep Disturbance | Benzodiazepine Dependence
Axsome Therapeutics, Inc.

Recruiting

Progressing TAAR-1, Dopamine, and Norepinephrine in Depression Using Solriamfetol (PARADIGM)

Major Depressive Disorder

United States
Cairo University

Not yet recruiting

Effect of Dexmedetomidine on Oxygenation and Lung Mechanics

Dexmedetomidine | Drug Use

Egypt
Suez Canal University

Not yet recruiting

Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone

Upper Extremity Injury
Barretos Cancer Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo; Farmoquimica S.A.; Hospital...

Not yet recruiting

Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated With Imiquimod

Biomarkers | HSIL, High-Grade Squamous Intraepithelial Lesions | Vaginal Microbiome

Search clinical trials for: Thrombopoietin receptor agonist

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