Search clinical trials for: Umbrella Study

Total 117805 results

University Health Network, Toronto

Recruiting

Umbrella Study for Single Patient Treatments in Oncology (UNIQUE)

Advanced Cancer | Rare Diseases

Canada
Pfizer
Arvinas Estrogen Receptor, Inc.; Carrick Therapeutics Limited

Recruiting

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Breast Cancer

United States, Belgium, Puerto Rico
Universitaire Ziekenhuizen KU Leuven
Innovative Medicines Initiative; BELpREG

Recruiting

UmbrelLACT Study: Clinical Lactation Study on the Exposure to Medicines Via Human Milk (UmbrelLACT)

Breast Feeding | Human Milk

Belgium
Tempus AI

Recruiting

Umbrella Study for Analysis of Data Related to Patients With Cancer (Polaris)

Cancer

United States
Fudan University

Recruiting

A Phase II Study of Advanced Salivary Gland Carcinoma Based on Molecular Typing

Advanced Salivary Gland Carcinoma

China
Hoffmann-La Roche

Recruiting

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study (UmbrellaMAX)

Cancer

Korea, Republic of, United Kingdom, Japan, Costa Rica, Belgium, Taiwan, Russian Federation, Mexico, Poland, France
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study B)

Breast Cancer

United States, Canada, Spain, Italy
Stemline Therapeutics, Inc.

Recruiting

Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer (ELEVATE)

Breast Cancer | Metastatic Breast Cancer

United States
Ruijin Hospital

Recruiting

A Umbrella Study in R/R PTCL Guided by Molecular Subtypes

Peripheral T Cell Lymphoma

China
Pfizer
Arvinas Estrogen Receptor, Inc.

Recruiting

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A)

Breast Cancer

United States, Canada, Spain, Italy
Yonsei University

Not yet recruiting

Study to Evaluate the Safety and Efficacy of Tislelizumab in Combination With Zanidatamab as a 2nd Line in HER2-Positive Advanced Gastric Cancer in K-Umbrella Trial

HER2-positive Gastric Cancer

Korea, Republic of
Pfizer

Recruiting

MagnetisMM-4: Umbrella Study of Elranatamab (PF-06863135) in Combination With Anti-Cancer Treatments in Multiple Myeloma

Multiple Myeloma

United States, Canada
University of British Columbia
University Health Network, Toronto; Janssen Inc.

Recruiting

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer (GUNS)

Prostate Cancer

Canada, United States
Peking University
Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China

Recruiting

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (VISIONARY)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Esophageal Squamous Cell Carcinoma | Biliary Tract Neoplasms | Unknown Primary Cancer | Digestive Cancer

China
Fudan University

Recruiting

Molecularly Targeted Umbrella Study in Luminal Advanced Breast Cancer (MULAN)

Breast Cancer | Metastatic Cancer

China
Merck Sharp & Dohme LLC

Recruiting

KEYMAKER-U01 Umbrella Master Study: Studies of Investigational Agents With Either Pembrolizumab (MK-3475) Alone or With Pembrolizumab PLUS Chemotherapy in Participants With Advanced Non-small Cell Lung Cancer (NSCLC) (MK-3475-U01/KEYMAKER-U01)

Carcinoma, Non-Small-Cell Lung

Poland, United States, Hungary, Israel, Italy, Korea, Republic of, Spain
Fudan University

Recruiting

FUSCC Refractory TNBC Umbrella (FUTURE) (FUTURE)

Triple-negative Breast Cancer

China
Yonsei University
Samsung Medical Center; AstraZeneca; Seoul National University Hospital; Korean... and other collaborators

Recruiting

An uMbrella Study of BIomarker-driven Targeted Therapy In Patients With Platinum-resistant Recurrent OvariaN Cancer(AMBITION)

Platinum-resistant Recurrent Ovarian Cancer

Korea, Republic of
Guangdong Association of Clinical Trials
Chinese Thoracic Oncology Group

Recruiting

Phase II Umbrella Study Directed by Next Generation Sequencing (TRUMP)

Carcinoma, Non-Small-Cell Lung

China
Samsung Medical Center

Recruiting

The Molecular Screening Study for the Umbrella Trial (SUKSES) in Relapsed Small Cell Lung Cancer Patients [SUKSES-S]

Neuroendocrine Carcinoma | Small Cell Lung Cancers

Korea, Republic of
Seoul National University Hospital

Active, not recruiting

DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer

Bile Duct Cancer | Chemotherapy Effect

Korea, Republic of
Hoffmann-La Roche

Active, not recruiting

An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma

Gastric and Gastroesophageal Junction Carcinoma

China
AstraZeneca

Active, not recruiting

Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy (HUDSON)

Non-Small Cell Lung Cancer

France, Spain, United States, Canada, Korea, Republic of, Austria, Israel, Germany
Incyte Corporation

Terminated

An Umbrella Study to Determine the Safety and Efficacy of Various Monotherapy or Combination Therapies in Neoadjuvant Urothelial Carcinoma (Optimus)

Urothelial Carcinoma

United States, France, Italy
Actelion

Completed

A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. (UMBRELLA)

Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Belgium, France, Poland, Russian Federation, Belarus, Turkey, Ukraine
Seoul National University Hospital
Chungnam National University Hospital; Korean Cancer Study Group

Completed

Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)]

Head and Neck Neoplasms | HNSCC

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Umbrella Study for HIV Infected Adults Enrolled in NIAID-Funded Interleukin-2 Studies

HIV Infections

United States
M.D. Anderson Cancer Center
National Center for Research Resources (NCRR)

Unknown

Initiative for Molecular Profiling in Advanced Cancer Therapy (IMPACT) Trial, An Umbrella Protocol

Advanced Cancers

United States
University of Toronto
Canadian Institutes of Health Research (CIHR); European Foundation for the...

Unknown

Umbrella Review and Updated Systematic Review and Meta-analysis of Pulses/Legumes and Incident Cardiometabolic Diseases

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Diabetes Mellitus, Type 2 | Coronary Heart Disease

Canada
Seoul National University Hospital

Unknown

A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy

Head and Neck Neoplasms | HNSCC

Korea, Republic of
Dr. Gaines W. Hammond Jr. MD FACS

Unknown

A Prospective Evaluation of the Catheter Science C3 "Umbrella Catheter."

Urinary Retention | Urinary Bladder, Neurogenic | Intermittent Catheterization

United States
M.D. Anderson Cancer Center

Completed

An Umbrella, Modular Study Based on Epidermal Growth Factor Receptor (EGFR) Mutation Status

Advanced Cancers

United States
National Cancer Institute (NCI)

Not yet recruiting

Natural History Study of Kaposi Sarcoma

HIV | Kaposi Sarcoma

United States
AstraZeneca

Not yet recruiting

Osimertinib With Chemotherapy as First-line Therapy for EGFR Mutation-positive NSCLC (FOREFRONT)

Neoplasms | Respiratory Tract Diseases | Lung Diseases | Neoplasms by Site | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms

China
Radicle Science

Recruiting

Radicle GI Health 24: A Study of Health and Wellness Products on GI Health and Related Health Outcomes

Abdominal Pain | Digestion | GI Disorders

United States
Laboratorios Sophia S.A de C.V.

Not yet recruiting

Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive®

Ocular Surface Disease | Dry Eye Disease | Dry Eye Sensation
Hull University Teaching Hospitals NHS Trust

Recruiting

An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough

Chronic Cough

United Kingdom
Austin Institute for Clinical Research
SkinCeuticals

Not yet recruiting

Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production

Acne
University of Pittsburgh
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); San... and other collaborators

Not yet recruiting

Real-time Engagement for Learning to Effectively Control Type 2 Diabetes (REFLECT2D)

Hyperglycemia | Diabetes Mellitus, Type 2 | Lifestyle | Physical Inactivity

United States
Quantum Surgical

Not yet recruiting

EPIBONE Study: a Prospective Study on Feasibility, Safety and Accuracy (EPIBONE)

Fractures, Bone | Bone Metastases | Bone Tumor
Beijing Tiantan Hospital

Not yet recruiting

Changes in Intravenous Anesthetic Drug Dosage in Insomnia Patients Undergoing Digestive Endoscopy

Insomnia | Digestive Endoscopy

China
National Medical Research Center for Cardiology...

Recruiting

Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI (ESMO-VASCMI)

Myocardial Infarction | Coronary Stenosis | Coronary Microvascular Dysfunction

Russian Federation
Jiangsu Simcere Pharmaceutical Co., Ltd.
Shanghai Xianxiang Medical Technology Co., Ltd.

Not yet recruiting

Study of SIM0500 Alone in Participants With Relapsed or Refractory Multiple Myeloma

Relapsed or Refractory Multiple Myeloma

China
Shanghai Juncell Therapeutics

Not yet recruiting

A Phase I Study on Engineering Tumor Infiltrating Lymphocytes Injection (GC203 TIL) for the Treatment of Advanced Malignant Solid Tumors (KUNLUN-001)

Breast Cancer | Gynecologic Cancer | Lung Cancer | Solid Tumor | Gastrointestinal Cancer
Lumos Labs, Inc.

Not yet recruiting

Task Atlas: Study to Develop a Task Atlas of Brain Recruitment During a Digital Game-based Program

Healthy Adults

United States
CalciMedica, Inc.

Not yet recruiting

A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk" (KOURAGE)

Acute Kidney Injury
Amgen

Not yet recruiting

A Phase 2, Dose Ranging Study Assessing Rocatinlimab in Moderate-to-severe Asthma

Asthma
AstraZeneca

Recruiting

Lung Cancer Screening Program Using Low-dose Tomography and Metabolomic Evaluation in a Public Service.

Lung Cancer

Brazil
Akili Interactive Labs, Inc.
Landmark College; Villa Maria College

Recruiting

EndeavorOTC® Research Study in College Students

Cognition | Attention | University Students

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Prospective Study of Whole-Brain RT Combined With Thiotepa Sheath Injection Combined With Systemic Therapy for the Primary Disease in the Treatment of Meningeal Metastases in Solid Tumors

Solid Tumor Leptomeningeal Metastasis

China

Search clinical trials for: Umbrella Study

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belarus

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations