Search clinical trials for: Zocor

Total 137 results

International Bio service

Not yet recruiting

Bioequivalence Study of Simvastatin 40 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
State University of New York - Downstate Medical...

Recruiting

Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer (C3)

Pancreatic Cancer Metastatic

United States
Emory University
National Cancer Institute (NCI)

Recruiting

Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Hormone Receptor-Positive Breast Carcinoma | HER2-Negative Breast Carcinoma

United States
Bobbie Jo Rimel, MD

Recruiting

Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer

Recurrent Ovarian Cancer | Platinum-sensitive Ovarian Cancer

United States
Charite University, Berlin, Germany
NeuroCure Clinical Research Center, Charite, Berlin; University Medical Center...

Recruiting

Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression (SIMCODE)

Obesity | Depressive Disorder, Major

Germany
Danae Hamouda, MD

Recruiting

Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

Advanced Solid Tumor | Advanced Pancreatic Cancer

United States
National Cancer Institute (NCI)

Active, not recruiting

Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis

Hepatocellular Carcinoma | Cirrhosis

United States, Puerto Rico
Sidney Kimmel Comprehensive Cancer Center at Johns...
Avon Foundation

Terminated

Detection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin

Breast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | Stage III Breast Cancer

United States
University of New Mexico
National Institute of Neurological Disorders and Stroke (NINDS); University...

Terminated

Permeability MRI in Cerebral Cavernous Malformations Type 1 in New Mexico: Effects of Statins

Cerebral Cavernous Malformations | Cavernous Angioma, Familial | Cerebral Cavernous Hemangioma

United States
Baylor Breast Care Center

Active, not recruiting

Simvastatin Plus Dual Anti-HER2 Therapy for Metastatic Breast Cancer (SIMPHONY)

Breast Cancer Stage IV

United States
Northwestern University
Astellas Pharma US, Inc.

Terminated

Women With Chest Pain and Normal Coronary Arteries Study

Chest Pain

United States
Mayo Clinic
Merck Sharp & Dohme LLC

Completed

The Acute Effect of Statins on Inflammatory Markers of Athersclerotic Tissue

Carotid Artery Disease
Baylor College of Medicine
Merck Sharp & Dohme LLC

Completed

Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome. (Merck-123)

Metabolic Syndrome

United States
Michael Simon
National Cancer Institute (NCI)

Completed

The Effect of Simvastatin on Breast Cancer Cell Growth in Women With Stage I-II Breast Cancer

Invasive Breast Carcinoma | Stage I Breast Cancer AJCC v7 | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage II Breast Cancer AJCC v6 and v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7

United States
Washington University School of Medicine
Duke University

Withdrawn

Simvastatin Nasal Rinses for the Treatment of COVID-19 Mediated Dysomsia (SimCA)

COVID-19 | Olfactory Disorder
National Cancer Institute (NCI)

Completed

Simvastatin in Reducing Pancreatitis in Patients With Recurrent, Acute or Chronic Pancreatitis

Acute Pancreatitis

United States
Amgen

Completed

LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2 (LAPLACE-2)

Hyperlipidemia

United States, Denmark, France, Italy, Czechia, Taiwan, Switzerland, Korea, Republic of, Germany, Hong Kong, Netherlands, Australia, Belgium, Canada, Hungary, South Africa, Russian Federation, Spain, United Kingdom, Sweden, Mexico
Brigham and Women's Hospital

Completed

Effect of Statin Use on Aldosterone Secretion

Healthy Subjects

United States
Madrigal Pharmaceuticals, Inc.
Celerion

Completed

Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin

Healthy

United States
Amarin Pharma Inc.

Completed

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (MARINE)

Hypertriglyceridemia

United States, Netherlands, Russian Federation, Ukraine, Denmark, Finland, Germany, India, Italy, Mexico, South Africa
Amarin Pharma Inc.

Completed

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (ANCHOR)

Hypertriglyceridemia

United States
Amarin Pharma Inc.

Completed

A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin (REDUCE-IT)

Cardiovascular Diseases

United States, Australia, Canada, India, Netherlands, New Zealand, Poland, Romania, Russian Federation, South Africa, Ukraine
Organon and Co

Terminated

Effect of Simvastatin on Endothelial Function in Premenopausal Women With Systemic Lupus Erythematosus (0733-271)(TERMINATED)

Systemic Lupus Erythematosus
Organon and Co

Completed

Aggrastat to Zocor (AtoZ) - the Use of Two Approved Drugs to Treat Patients Who Have Experienced Chest Pain or a Heart Attack (0733-180)

Acute Coronary Syndrome
Organon and Co

Completed

EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)

Atherosclerosis
Organon and Co

Completed

Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)

Hypercholesterolemia
Organon and Co

Completed

Study To Assess The Efficacy Of A Cholesterol Lowering Drug On Top Of Statins In Patients After Myocardial Infarction (MI)(0653A-150)

Cardiovascular Disorder
Organon and Co

Completed

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Hypercholesterolemia
Organon and Co
Merck Sharp & Dohme LLC

Completed

Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)

Atherosclerosis | Hypercholesterolaemia
Organon and Co

Completed

Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)

Diabetes Mellitus | Cardiovascular Disorder
Organon and Co

Completed

IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103)

Myocardial Infarction | Hypercholesterolemia
VA Office of Research and Development

Completed

Simvastatin for mTBI

TBI-Traumatic Brain Injury

United States
Craig Hospital

Active, not recruiting

Simvastatin to Prevent SCI-Induced Bone Loss

Osteoporosis | Spinal Cord Injuries

United States
Chinese University of Hong Kong

Completed

The Interaction of Herbs and Statins

Drug Interaction

Hong Kong
Columbia University
Children's Hospital of Philadelphia

Terminated

Feasibility Study of Simvastatin in Hodgkin's Lymphoma Survivors

Carotid Artery Disease

United States
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Merck...

Completed

Clinical Trial of Zocor (Simvastatin) and Vytorin (Ezetimibe/Simvastatin) in Adolescents With Type 1 Diabetes

Dyslipidemia | Type 1 Diabetes Mellitus

United States
Iris Sommer
Stanley Medical Research Institute

Completed

Simvastatin Addition for Patients With Recent-onset Schizophrenia

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder | Psychosis NOS

Netherlands
University of Pennsylvania
The LAM Foundation

Completed

Safety of Simvastatin in LAM and TSC (SOS)

Tuberous Sclerosis Complex | Lymphangioleiomyomatosis

United States
Medical College of Wisconsin

Completed

Effect of Diabetes Mellitus on Cholesterol Metabolism

Type 2 Diabetes Mellitus | Hypercholesterolemia | Type 1 Diabetes Mellitus

United States
Emory University
Children's Healthcare of Atlanta

Completed

Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors (AflacST1402)

Renal Cell Carcinoma | Osteosarcoma | Rhabdoid Tumor | Neuroblastoma | Retinoblastoma | Rhabdomyosarcoma | Wilms Tumor | Hepatoblastoma | Ewings Sarcoma | Non-rhabdomyosarcoma Soft Tissue Sarcoma | Germ Cell Tumors | Clear Cell Sarcoma

United States
Samsung Medical Center

Unknown

Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients

Adenocarcinoma of Rectum

Korea, Republic of
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)

Peripheral Arterial Disease

United States
Immunogenics, LLC

Completed

Simvastatin Metabolism as a Test for CD Activity (IRB 15-007568]

Celiac Disease

United States
University of Maryland, Baltimore
Merck Sharp & Dohme LLC

Completed

Simvastatin With or Without Ezetimibe and Atherothrombotic Biomarker Assessment

Metabolic Syndrome

United States
University of Louisville
James Graham Brown Cancer Center

Terminated

Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid

Multiple Myeloma

United States
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

SLOS: The Effect of Simvastatin in Patients Receiving Cholesterol Supplementation

Smith-Lemli-Opitz Syndrome

United States
Imperial College London
Medical Research Council

Completed

Simvastatin as a Treatment for Pulmonary Hypertension

Pulmonary Hypertension

United Kingdom, Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Simvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast Cancer

Breast Cancer

United States
University of Wisconsin, Madison
Merck Sharp & Dohme LLC; National Institute on Aging (NIA); American Federation... and other collaborators

Completed

Evaluating Simvastatin's Potential Role in Therapy (ESPRIT)

Alzheimer Disease

United States
Merck Sharp & Dohme LLC

Completed

MK-0524B Lipid Study (MK-0524B-063)

Mixed Dyslipidemia | Primary Hypercholesterolemia

Search clinical trials for: Zocor

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