Search clinical trials for: adult brain stem glioma

Total 72610 results

University of Florida
Oligo Nation, Inc

Not yet recruiting

ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients (ADAGiO)

Recurrent Oligodendroglioma | Progressive Oligodendroglioma

United States
Seattle Children's Hospital

Recruiting

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Refractory Primary Malignant Central Nervous System Neoplasm | Recurrent CNS Tumor, Adult | Recurrent, CNS Tumor, Childhood

United States
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium; Chimerix

Recruiting

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0 (BIOMEDE 2)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

France
Bambino Gesù Hospital and Research Institute

Recruiting

GD2-CAR T Cells for Pediatric Brain Tumours

High Grade Glioma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Embryonal Tumor | Brain Tumor Adult | Brain Tumor, Pediatric

Italy
Seattle Children's Hospital

Recruiting

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

Glioma | Ependymoma | Medulloblastoma, Childhood | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma | Central Nervous System Tumor | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Pineoblastoma, Childhood

United States
University of Florida
Accelerate Brain Cancer Cure; Lyla Nsouli Foundation

Active, not recruiting

Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I) (BRAVO)

Brain Stem Glioma | Diffuse Intrinsic Pontine Glioma (DIPG)

United States
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium; Curis, Inc.; Cannonball Kids' Cancer...

Active, not recruiting

Fimepinostat in Treating Brain Tumors in Children and Young Adults (PNOC016)

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Diffuse Intrinsic Pontine Glioma | Recurrent Anaplastic Astrocytoma

United States, Switzerland
Memorial Sloan Kettering Cancer Center

Completed

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer

Sarcoma | Small Intestine Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Metastatic Cancer | Neuroblastoma | Intraocular Melanoma | Melanoma (Skin) | Retinoblastoma

United States
Stemline Therapeutics, Inc.

Completed

Safety and Efficacy Study of SL-701, a Glioma-Associated Antigen Vaccine To Treat Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme | Adult Brain Glioblastoma

United States
City of Hope Medical Center

Active, not recruiting

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

Unspecified Childhood Solid Tumor, Protocol Specific | Solid Tumor | Ewing Sarcoma | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Adult Brain Tumor | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Completed

Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors

Bone Cancer | Brain Tumor | Kidney Tumor | Childhood Soft Tissue Sarcoma | Childhood Liver Cancer

United States
National Institutes of Health Clinical Center (CC)

Completed

Stereotactic Radiosurgery in Treating Patients With Brain Tumors

Brain Metastases | Adult Ependymoma | Adult Oligodendroglioma | Adult Brain Stem Glioma | Adult Craniopharyngioma | Adult Medulloblastoma | Adult Central Nervous System Germ Cell Tumor | Adult Malignant Meningioma | Adult Meningioma | Mixed Gliomas | Adult Noninfiltrating Astrocytoma | Adult Pineal Parenchymal... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Fluorine F 18 Fluorodopa-Labeled PET Scan in Planning Surgery and Radiation Therapy in Treating Patients With Newly Diagnosed High- or Low-Grade Malignant Glioma

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Millennium Pharmaceuticals, Inc.

Completed

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma | Recurrent... and other conditions

United States
CHA University
Ajou University School of Medicine

Completed

Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients (MSC11FCD-GBM)

Neoplasms, Germ Cell and Embryonal | Glioblastoma | Recurrent Glioblastoma | Adult Gliosarcoma | Neoplasms, Brain

Korea, Republic of
University of Michigan Rogel Cancer Center

Terminated

Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

Glioma | High Grade Glioma | Pontine Tumors

United States
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; University of Colorado... and other collaborators

Completed

External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas

Brain Cancer

United States, Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas

Anaplastic Oligoastrocytoma | Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Tumor

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Brain Tumors | Metastatic Disease

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors

Fatigue | Cognition Disorders | Brain Tumors | Nervous System Tumors

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

Brain and Central Nervous System Tumors | Radiation Toxicity

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors

Depression | Quality of Life | Fatigue | Brain and Central Nervous System Tumors | Cognitive/Functional Effects

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Proton Beam Radiation Therapy in Treating Patients With Low Grade Gliomas

Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pineal Gland Astrocytoma | Recurrent Adult Brain Tumor | Adult Brain Stem Glioma | Adult Grade II Meningioma | Adult Meningeal Hemangiopericytoma | Adult Pineocytoma | Adult Brain Tumor | Adult Melanocytic Lesion

United States
Case Comprehensive Cancer Center

Completed

Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Disorders

Brain and Central Nervous System Tumors | Metastatic Cancer | Radiation Toxicity

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Sodium Stibogluconate and IFNa-2b Followed By CDDP, VLB and DTIC Treating Pts.With Advanced Melanoma or Other Cancers

Stage IV Melanoma

United States
University of Michigan Rogel Cancer Center

Withdrawn

A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas

Glioma | Diffuse Intrinsic Pontine Glioma

United States
National Cancer Institute (NCI)
NRG Oncology; Radiation Therapy Oncology Group

Completed

Dasatinib in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Neoplasm

United States, Canada, Saudi Arabia
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Study of Blood and Cheek Cell Samples From Patients With Glioma

Brain and Central Nervous System Tumors

United States
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium

Unknown

Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication (BIOMEDE)

Diffuse Intrinsic Pontine Glioma

France
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Terminated

Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy

Thrombocytopenia | Brain and Central Nervous System Tumors

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Yoga Therapy in Treating Patients With Malignant Brain Tumors

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pineal Gland Astrocytoma | Recurrent Adult... and other conditions

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors

Brain and Central Nervous System Tumors | Metastatic Cancer

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Patients With Brain Stem Glioma

Brain Stem Gliomas

United States
Masonic Cancer Center, University of Minnesota

Terminated

MT2004-30: Tomotherapy for Solid Tumors

Sarcoma | Kidney Cancer | Brain and Central Nervous System Tumors | Retinoblastoma | Liver Cancer

United States
Masonic Cancer Center, University of Minnesota

Terminated

Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors

Sarcoma | Kidney Cancer | Ovarian Cancer | Brain and Central Nervous System Tumors | Chordoma | Neuroblastoma | Retinoblastoma | Liver Cancer | Childhood Germ Cell Tumor

United States
City of Hope Medical Center

Completed

A Pilot Feasibility Study of Oral 5-Fluorocytosine and Genetically-Modified Neural Stem Cells Expressing E.Coli Cytosine Deaminase for Treatment of Recurrent High Grade Gliomas

Recurrent High Grade Glioma | Adult Anaplastic Astrocytoma | Adult Anaplastic Oligodendroglioma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Recurrent Adult Brain Tumor | Recurrent Grade III Glioma | Adult Brain Tumor | Recurrent Grade IV Glioma | Adult Anaplastic...

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent or Refractory High-Grade Malignant Glioma

Brain and Central Nervous System Tumors
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma

Brain and Central Nervous System Tumors

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors

Infertility | Brain and Central Nervous System Tumors | Chemotherapeutic Agent Toxicity

United States
Sue O'Dorisio
National Cancer Institute (NCI); Ride for Kids

Withdrawn

Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors

Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Untreated Childhood Brain Stem Glioma | Untreated Childhood Medulloblastoma | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma and other conditions

United States
St. Jude Children's Research Hospital
Arog Pharmaceuticals, Inc.; The V Foundation for Cancer Research

Completed

PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma

Diffuse Intrinsic Pontine Glioma | Progressive or Refractory High-Grade Glioma

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Melphalan With BBBD in Treating Patients With Brain Malignancies

Lymphoma | Brain and Central Nervous System Tumors | Metastatic Cancer

United States
University of Southern California
National Cancer Institute (NCI)

Terminated

Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases

Multiple Sclerosis | Metastatic Malignant Neoplasm in the Brain | Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult... and other conditions

United States
Erik Mittra
National Cancer Institute (NCI)

Terminated

18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas

Untreated Childhood Brain Stem Glioma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Patients With Recurrent Glioma

Brain and Central Nervous System Tumors

United States
St. Jude Children's Research Hospital

Completed

DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma

Brain Tumors | Central Nervous System Tumors

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Weill Medical College of Cornell University; Schering-Ploug...

Completed

Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma

Brain and Central Nervous System Tumors

United States
University Hospital, Montpellier

Completed

Study of Tissue Samples From Patients With Glioma or Other Brain Tumors

Central Nervous System Lymphoma

France

Search clinical trials for: adult brain stem glioma

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