Search clinical trials for: denosumab

Total 299 results

Washington University School of Medicine
United States Department of Defense; Aclaris Therapeutics, Inc.

Not yet recruiting

Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer

United States
Taizhou Mabtech Pharmaceutical Co.,Ltd

Recruiting

Study of CMAB807 Post-change in Manufacturing Site and Prolia in Healthy Volunteers

Healthy Volunteers

China
Amgen

Not yet recruiting

Evaluation of Efficacy and Safety of Prolia in Subjects of Male Osteoporosis in Mainland China

Osteoporosis
RenJi Hospital
Shanghai JMT-Bio Inc.

Not yet recruiting

Narlumosbart Compared With Denosumab in Patients With Multiple Myeloma Bone Disease

Multiple Myeloma | Bone Diseases
Xentria, Inc.

Not yet recruiting

Single Dose, Three-arm Study to Compare the Pharmacokinetic Similarity of MAB-22 Versus Prolia®

Healthy Participants
Martin Blomberg Jensen

Not yet recruiting

NAPO - Novel Approach for Oligospermia (NAPO)

Infertility, Male

Denmark
Yonsei University

Not yet recruiting

Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients

Sarcopenia

Korea, Republic of
424 General Military Hospital

Recruiting

Sequential Therapies After Osteoanabolic Treatment (START)

Osteoporosis, Postmenopausal

Greece, Germany, Italy
Wuhan Union Hospital, China

Not yet recruiting

Clinical Controlled Study on the Efficacy of Denosumab in Treating Osteoporosis in the Domestic Population and Its Impact on Sarcopenia-related Outcomes

Sarcopenia | Osteoporosis | Denosumab

China
Susan L. Greenspan

Recruiting

Preserving Geriatric Muscle With an Osteoporosis Medication

Osteoporosis

United States
Assiut University

Not yet recruiting

Palbociclib Induced Neutropenia; Risk Factors and Treatment Outcome in Metastatic Breast Cancer Patients

Metastatic Breast Cancer

Saudi Arabia
Case Comprehensive Cancer Center
The Cleveland Clinic; Biofrontera, Inc.

Recruiting

Short Contact Protocols to Reduce Pain During 10% ALA Gel Red-light Photodynamic Therapy of Actinic Keratoses

Actinic Keratosis

United States
Natasha Appelman-Dijkstra

Recruiting

DEnosumab for the Treatment of FIbrous Dysplasia/McCune-Albright Syndrome in Adults (DeFiD) (DeFiD)

Fibrous Dysplasia | McCune Albright Syndrome

Netherlands
Xi'an Honghui Hospital
Chugai Pharma China Co., Ltd.

Recruiting

Comparison of Efficacy of Denosumab With Eldecalcitol or Native Vitamin D in Postmenopausal Women With Osteoporosis.

Osteoporosis in Postmenopausal Women

China
Peking Union Medical College Hospital

Not yet recruiting

Study of the Key Techniques of Prevention and Treatment of Osteoporotic Refracture

Osteoporotic Fractures
Luye Pharma Group Ltd.

Recruiting

Comparative Efficacy, Safety, PK, and Immunogenicity Study of LY06006 and EU-Prolia in Postmenopausal Women With Osteoporosis

Osteoporosis, Postmenopausal

China
Shanghai JMT-Bio Inc.

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Narlumosbart (JMT103) in Patients With Giant Cell Tumor of Bone

Giant Cell Tumor of Bone

China
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

Comparing of the PK, PD, Safety and Immunogenicity of HS-20090 and Xgeva® in Healthy Adults

Healthy

China
Capital Medical University

Recruiting

Denosumab Treatment in CKD Patients at High Risk of Fracture

Chronic Kidney Diseases | End Stage Renal Disease | Fracture | Bone Density, Low

China
Shenzhen People's Hospital

Recruiting

Denosumab vs Alendronate After Vertebroplasty

Denosumab Allergy

China
Aarhus University Hospital

Recruiting

Treatment With Zoledronate Subsequent to Denosumab in Osteoporosis 2

Osteoporosis, Postmenopausal

Denmark
Shenzhen People's Hospital

Recruiting

Denosumab vs Zoledronate After Lumbar Fusion

Osteopenia | Lumbar Spondylolisthesis

China
Dong-A ST Co., Ltd.

Recruiting

Efficacy and Safety of Actonel® After Denosumab Discontinuation in Postmenopausal Osteoporosis Women

Postmenopausal Osteoporosis

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Recruiting

Observational Study of Bone Complications in People With Post-menopausal Breast Cancer Who Have Stopped Treatment With Denosumab and Aromatase Inhibitors

Breast Cancer

United States
424 General Military Hospital

Recruiting

Single or Repeat Zoledronate Versus Alendronate Following Denosumab (EUROpean Denosumab Effects Consolidation Study) (EURODEC)

Osteoporosis, Postmenopausal

Greece, France, Germany, Italy
The Affiliated Hospital of Qingdao University

Not yet recruiting

Effects of Denosumab on Bone Microarchitecture After Total Knee Arthroplasty

Osteoarthritis, Knee
Aristotle University Of Thessaloniki
424 General Military Hospital

Recruiting

Effect of Anti-osteoporotic Medications on Nonalcoholic Fatty Liver Disease (OsteoNAFLD)

Osteoporosis, Postmenopausal | Nonalcoholic Fatty Liver

Greece
Second Affiliated Hospital of Soochow University

Not yet recruiting

PraG With RANKL Inhibitor for the Treatment of Advanced Multiple Metastatic Solid Tumors (PRaG 2X)

Metastatic Solid Tumor

China
Lambda Therapeutic Research Ltd.
Intas Pharmaceutical Limited (Biopharma Division)

Recruiting

Denosumab Biosimilar Injection in Post Menopausal Women With Osteoporosis

Osteoporosis, Postmenopausal

India
National Institute of Dental and Craniofacial Research...

Recruiting

Study of Denosumab for Prevention of Skeletal Disease Progression in Children With Fibrous Dysplasia

Fibrous Dysplasia

United States
Enzene Biosciences Ltd.
Alkem Laboratories Ltd

Recruiting

A Phase 3 Study to Compare Biosimilar Denosumab With Prolia®

Postmenopausal Osteoporosis

Czechia
University of Calgary

Recruiting

Efficacy of Zoledronic Acid to Prevent Bone Loss Following Denosumab Discontinuation

Osteoporosis | Bone Loss | Osteopenia | Osteoporosis, Postmenopausal

Canada
Shanghai JMT-Bio Inc.

Recruiting

Efficacy and Safety of JMT103 in the Treatment of Postmenopausal Women With Osteoporosis

Postmenopausal Osteoporosis

China
Enzene Biosciences Ltd.
Alkem Laboratories Ltd

Recruiting

Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Biosimilar Denosumab With Prolia® in Healthy Adult Male Volunteers

Healthy Male Subjects

Bulgaria, Poland
University Hospital, Montpellier

Not yet recruiting

Study Evaluating Denosumab on Vascular and Bone Metabolism in Osteoporotic Chronic Kidney Disease (HDENOBS) (HDENOBS)

Osteoporosis | Chronic Kidney Disease 5D
Martin Blomberg Jensen

Recruiting

FITMI - First In Treating Male Infertility

Infertility, Male

Denmark
Shanghai Changzheng Hospital

Recruiting

Effects of Denosumab on Bone Fusion in Osteoporotic Patients After Lumbar Fusion

Osteoporosis | Fusion of Spine, Lumbar Region

China
James J. Peters Veterans Affairs Medical Center
Kessler Institute for Rehabilitation

Recruiting

Treatment With Romosozumab to Improve Bone Mineral Density and Architecture in Chronic SCI

Osteoporosis | Spinal Cord Injuries

United States
Shenzhen People's Hospital

Recruiting

Denosumab vs Zoledronic Acid and Osteoporotic Compression Fracture

Denosumab vs Zoledronate

China
Western University, Canada
Western University; The Kidney Foundation of Canada; Academic Medical Organization... and other collaborators

Recruiting

PRevEnting FracturEs in REnal Disease 1 (PREFERRED-1)

Kidney Diseases | Chronic Kidney Disease-Mineral and Bone Disorder | Fragility Fracture | Dialysis; Complications

Canada
National Taiwan University Hospital

Recruiting

The Optimal Long Term Treatment Strategy of Anti-resorptive Medications---The Extension of Denosumab Sequential Therapy

Osteoporosis | Bone Mineral Density

Taiwan
National Taiwan University Hospital

Recruiting

The Optimal Sequential Therapy After Long Term Denosumab Treatment

Osteoporosis

Taiwan
Shanghai Hansoh Biomedical Co., Ltd

Recruiting

Comparing of the Pharmacokinetic, Safety and Immunogenicity of HS-20090-2 Injection and Prolia® in Healthy Adults

Postmenopausal Osteoporosis

China
Redx Pharma Plc

Recruiting

A Study to Assess Efficacy of RXC004 +/- Nivolumab in Ring Finger Protein 43 (RNF43) or R-spondin (RSPO) Aberrated, Metastatic, Microsatellite Stable, Colorectal Cancer After Progression on Standard of Care (SOC)

Colorectal Cancer

Korea, Republic of, Spain, United States, United Kingdom
University General Hospital of Heraklion

Recruiting

Osteoporosis Treatment Protocol in Patients With Fragility Fractures: Application and Efficacy

Osteoporosis

Greece
Luye Pharma Group Ltd.

Recruiting

Efficacy and Safety of LY01011 and Xgeva® in Patients With Bone Metastases From Solid Tumors

Bone Metastases From Solid Tumors

China
Columbia University
Amgen

Recruiting

Romosozumab/Denosumab Study for Premenopausal IOP

Premenopausal Idiopathic Osteoporosis

United States
Copenhagen University Hospital at Herlev
Institut Straumann AG; Amgen

Recruiting

Outcome of Dental Implant Therapy in Patients Treated With Antiresorptive Medication

Cancer | Osteoporosis | Missing Teeth | Implants

Denmark
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Austrian Breast & Colorectal Cancer Study...

Recruiting

Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation (BRCA-P)

Neoplasms | Breast Cancer | Breast Neoplasms | Breast Diseases | Breast Carcinoma | BRCA1 Mutation

United States
Australian and New Zealand Intensive Care Research...

Recruiting

Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults (BoneZone)

Critical Illness | Osteoporosis

Australia, New Zealand

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