Search clinical trials for: gene variant

Total 266560 results

University of Colorado, Denver
Children's Hospital Colorado

Recruiting

Generating Advancements Through Longitudinal Analysis in X and Y Variations (GALAXY) (GALAXY)

Sex Chromosome Aneuploidy

United States
Alnylam Pharmaceuticals

Not yet recruiting

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Hereditary Amyloidosis, Transthyretin-Related | Asymptomatic Carrier State

France
University Hospital, Lille
France Alzheimer

Not yet recruiting

Social & Affective Cognition in Alzheimer's Disease & Associated Disorders (SOCIALIZE)

Alzheimer's Disease | Frontotemporal Degeneration (Semantic & Behavioral Variants)
National Cancer Institute (NCI)

Not yet recruiting

Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia

Recurrent Hairy Cell Leukemia | Recurrent Hairy Cell Leukemia Variant
University Hospital Tuebingen

Recruiting

Non-Invasive Plasma Treatment for Cervical Infections: Targeting High- and Low-Risk HPV Variants

Cervical Cancer | HPV Infection

Germany
Medanta, The Medicity, India

Recruiting

Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes

Type2diabetes

India
Universidad de Colima

Recruiting

Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics (FAPD_RCT)

Functional Gastrointestinal Disorders | Functional Abdominal Pain Syndrome | Irritable Bowel Syndrome Variant of Childhood

Mexico
Assistance Publique - Hôpitaux de Paris

Recruiting

Effect of Peripheral VA-ECMO Flow Variations on the Pulmonary Arterial Occlusion Pressure (PAPO) in Patients With Refractory Cardiogenic Shock. (PAPO-Flow)

Cardiogenic Shock

France
Nantes University Hospital
AXA Assurances VIE Mutuelle

Not yet recruiting

Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome (BIOMINRISK)

Sudden Infant Death | Sudden Unexplained Infant Death

France
University of Cambridge
Sanofi

Recruiting

Molecular Imaging in Fabry Disease of the Heart

Fabry Disease, Cardiac Variant

United Kingdom
IRCCS San Raffaele

Recruiting

Integrated PET/MRI and Germline Variants to Differentiate Brain Tumopr Recurrence From Iatrogenicchanges in Children

Pediatric Brain Tumor

Italy
University of Copenhagen
Gentofte Hospital, Denmark

Recruiting

The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function (H-21044858)

Incretin Effect

Denmark
Oscar Gerardo Arrieta Rodríguez

Recruiting

Pathogenic Variants in Genes Associated With Lung Adenocarcinoma

Lung Adenocarcinoma

Mexico
WestVac Biopharma Co., Ltd.
WestVac Biopharma (Guangzhou) Co., Ltd.

Not yet recruiting

A Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of Booster Vaccination With Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell)

COVID-19
Amsterdam UMC, location VUmc
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

SCS for Vasospastic Angina Vasospastic Angina Pectoris - a Prospective Study (VAP)

Angina Pectoris; Angiospastic
Hospital do Rim e Hipertensão

Recruiting

Evaluation of APOL1 Gene Variants in Kidney Donors and Their Impact on Long-term Renal Function in Donors and Recipients

Kidney Diseases | Transplant Failure

Brazil
Lexeo Therapeutics

Recruiting

Gene Therapy for ACM Due to a PKP2 Pathogenic Variant

Arrhythmogenic Cardiomyopathy | PKP2-ACM | PKP2-ARVC

United States
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; Centre National...

Recruiting

Building of a Diagnostic/Prognostic Database for Human ERG Variant Effects (CarDiag)

Long QT Syndrome

France
Central Hospital, Nancy, France

Recruiting

Olfactory Cleft Stenosis and Obstruction on Paranasal Sinus CT Scan in Pre Septo Rhinoplasty Patients Without Respiratory Mucosa Pathology : Normal Variants or Pathologic Findings ?

Olfactory Impairment

France
AviadoBio Ltd

Recruiting

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN) (ASPIRE-FTD)

Frontotemporal Dementia | FTD | FTD-GRN | Dementia, Frontotemporal

Netherlands, Spain, Poland
Nantes University Hospital

Not yet recruiting

Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders

Bipolar Disorder | Behavioral Variant of Frontotemporal Disorder (bvFTD) | Phenocopy Frontotemporal Dementia (phFTD) | Frontal Variant of Alzheimer Disease
Mario Negri Institute for Pharmacological Research

Recruiting

New Analytic Tools for aHUS and C3G Diagnosis (COMPRare)

Healthy | Hemolytic-Uremic Syndrome | Membranoproliferative Glomerulonephritis

Italy
Novavax

Not yet recruiting

Phase 3 Adolescent Study for SARS-CoV-2 rS Variant Vaccines (COVID-19)

COVID-19

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Lymph Node Aspiration to Decipher the Immune Response of Beta-variant Recombinant Protein Booster Vaccine (VidPrevtyn Beta, Sanofi) Compared to a Bivalent mRNA Vaccine (Comirnaty Original/Omicron BA.4-5, BioNTech-Pfizer) in Adults Previously Vaccinated With at Least 3 Doses of COVID-19 mRNA Vaccine. (LymphoBOOST)

COVID-19

France
University of Florida
Johns Hopkins University; Massachusetts General Hospital; Washington University... and other collaborators

Recruiting

Automated Imaging Differentiation of Parkinsonism (AIDP)

Parkinson Disease | Progressive Supranuclear Palsy | Multiple System Atrophy, Parkinson Variant

United States, Canada
David Ho
US Military HIV Research Program; Henry M. Jackson Foundation for the Advancement... and other collaborators

Recruiting

10E8.4/iMab Bispecific Antibody and VRC07-523LS Monoclonal Antibody in HIV-infected Adults

HIV-1-infection

Tanzania
Rocket Pharmaceuticals Inc.

Recruiting

A Phase 1, Dose Escalation Trial of RP-A601 in Subjects With PKP2 Variant-Mediated Arrhythmogenic Cardiomyopathy (PKP2-ACM)

PKP2 Arrhythmogenic Cardiomyopathy (PKP2-ACM)

United States
University Hospital, Montpellier

Recruiting

Search for Structural Variants in Patients With DSD and Inconclusive Molecular Diagnosis (GENEXPLOR)

Disorder of Sex Development, 46,XY

France
Institut Pasteur
Biogroup Laboratoire de biologie médicale

Not yet recruiting

Understanding the Determinants of Mucosal Immunity and Optimizing the Diagnosis of Infection With SARS-CoV-2 Variants (COVARIANT)

COVID-19
Hospital Universitari Vall d'Hebron Research Institute
Hospital Universitario La Paz

Not yet recruiting

Identification and Characterization of Genetic Variants in Hereditary Angioedema (GENOMAEH_01)

Hereditary Angioedema With C1 Esterase Inhibitor Deficiency

Spain
Carnegie Mellon University

Not yet recruiting

Heads up Messages to Increase Call Pick-up Rates

Various: Health Insurance Members That Could Benefit From Being Connected to a Specialist, e.g., Orthopedic Doctor to Treat Back Pain
Beijing Tsinghua Chang Gung Hospital
Beijing DCTY® Biotech Co.,Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerance and Initial Efficacy of EGFRvIII CAR-T on Glioblastoma

Recurrent Glioblastoma
Qianfoshan Hospital

Recruiting

Efficacy of Lianhua Qingwen in Treating Patients Infected With the Omicron Variant of the COVID-19

COVID-19 Pneumonia

China
Dana-Farber Cancer Institute
Nest Genomics

Recruiting

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Genetic Predisposition to Disease | Genetic Predisposition

United States
University Hospital, Basel, Switzerland

Recruiting

Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases (NEUTROSKIN)

Inflammatory Dermatoses | Neutrophil-mediated Inflammatory Dermatoses

Switzerland
Rigshospitalet, Denmark

Not yet recruiting

Follow-up Study on Female Carriers With DMD Gene Variants

Muscular Dystrophy | Duchenne Muscular Dystrophy | Becker Muscular Dystrophy

Denmark
University Hospital Muenster

Recruiting

Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.

Sepsis | Pre-Eclampsia | Adiposity | Microscopic Polyangiitis | Granulomatosis With Polyangiitis | SIRS | Procalcitonin

Germany
Thomas Ernst, PD Dr. med.
AbbVie; Ludwig-Maximilians - University of Munich

Recruiting

Venetoclax After TKI to Target Persisting Stem Cells in CML (VARIANT)

Chronic Myeloid Leukemia

Germany
Asklepios Biopharmaceutical, Inc.

Recruiting

Pre-Gene Therapy Study in Parkinson's Disease and Multiple System Atrophy

Parkinson's Disease | Multiple System Atrophy | Multiple System Atrophy, Parkinson Variant

United States, Poland
University Health Network, Toronto
Weston Brain Institute

Recruiting

Subgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia (FRONSTIM)

Frontotemporal Dementia | Deep Brain Stimulation

Canada
University Hospital, Bordeaux

Recruiting

Functional Tests to Resolve Unsolved Rare Diseases. Rares. (RID)

Intellectual Disability | Cystic Fibrosis | Neurodegeneration With Brain Iron Accumulation (NBIA) | Congenital Heart Defect | Albinism | Rubinstein-Taybi Syndrome | Periventricular Nodular Heterotopia

France
St. Louis University
Mid-America Transplant

Recruiting

APOL1 Genetic Testing in African Americans

Chronic Kidney Diseases | Genetic Predisposition | Nephropathy

United States
Nantes University Hospital

Recruiting

Autobiographical Specificity (ESAD)

Alzheimer Disease | Frontotemporal Dementia | Memory

France
University Hospital, Antwerp

Recruiting

ReACHallenge Trial: Acetylcholine Rechallenge After Pretreatment With Vasoactive Drugs (ReACHallenge)

Angina Pectoris, Variant | Angina Pectoris; Spasm-Induced | Angina Pectoris With Normal Coronary Arteriogram

Belgium
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Recruiting

A Trial Evaluate the Immunogenicity and Safety of Recombinant COVID-19 Omicron-Delta Variant Vaccine (CHO Cell)

COVID-19

Uzbekistan
Lille Catholic University
Variant Bio, Inc.

Recruiting

Genetic of Chronic Kidney Disease and Gout in New Caledonia (CALEDGOUTCKD)

Renal Insufficiency, Chronic | Gout

New Caledonia
Fudan University
Amoy Diagnostics Co., LTD

Recruiting

Assessment of Prognosis Using Peripheral Blood Circulating Tumor DNA in Patients With Cervical Cancer

Locally Advanced Cervical Cancer

China
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Azithromycin Treatment for Non-eosinophilic Chest Tightness Variant Asthma

Asthma | Effect of Drug | Azithromycin | Chest Syndrome

China
Jaeb Center for Health Research
Foundation Fighting Blindness

Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants (Uni-Rare)

Retinitis Pigmentosa | Inherited Retinal Degeneration

United States, United Kingdom, France, Brazil, Canada, Finland, Israel, Mexico, Netherlands, Switzerland, Australia
Hospital Garcia de Orta
Instituto de Medicina Molecular João Lobo Antunes

Recruiting

Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants (SepticHeartG)

Septic Shock | Cardiomyopathies | Diastolic Dysfunction

Portugal

Search clinical trials for: gene variant

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