Search clinical trials for: pharmacokinetic

Total 12653 results

Bio-Thera Solutions

Not yet recruiting

An Evaluation of BAT 8010 for Injection in Combination With BAT 1006 in Locally Advanced or Metastatic Entities Safety, Tolerability, Pharmacokinetic Profile, and Initial Clinical Efficacy of the Tumor in Patients Multicenter, Open Phase Ib/IIa Clinical Study

Advanced Solid Tumors
Cairo University
Theodor Bilharz Research Institute

Not yet recruiting

Analgesic Effect of Melatonin and Vitamin C Administration, Alone or In Combination in Major Abdominal Surgery.

Postoperative Pain

Egypt
Ganzhou Hemay Pharmaceutical Co., Ltd

Not yet recruiting

To Evaluate the Pharmacokinetics of Hemay005 Tablets in Subjects With Liver Damage

Psoriasis
University Hospital Southampton NHS Foundation...

Not yet recruiting

Haemoglobin And Vancomycin Pharmacokinetics in the Cerebrospinal Fluid Following Subarachnoid Haemorrhage (HAPTO)

Subarachnoid Hemorrhage
Qilu Pharmaceutical Co., Ltd.

Not yet recruiting

A Study Comparing Pharmacokinetic and Safety of QL2109 and DARZALEX FASPRO® in Healthy Adults

Tumor

China
Pfizer

Not yet recruiting

A Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without Food

Healthy Volunteers
University of Aarhus

Recruiting

Pharmacokinetics of Dexamethasone in Childhood ALL and Reduction in Bone Mineral Density

Acute Lymphoblastic Leukemia

Denmark
AstraZeneca

Not yet recruiting

A Study to Investigate the Safety and Pharmacokinetics of AZD6793 in Healthy Japanese and Chinese Participants

Healthy Participants

United States
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
Cerevel Therapeutics, LLC

Not yet recruiting

A Trial to Evaluate the Effect of Esomeprazole on the Pharmacokinetics of Emraclidine in Healthy Adult Participants

Healthy Participants
Peking Union Medical College Hospital
Xiangya Hospital of Central South University; Ruijin Hospital; China-Japan Friendship...

Recruiting

The Study of Monitoring and Dosing Guidance of Direct Oral Anticoagulants Based on Pharmacokinetics, Pharmacodynamics, and Pharmacogenomics

Pulmonary Embolism

China
PMV Pharmaceuticals, Inc

Recruiting

A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants

Healthy Volunteers

United States
Eli Lilly and Company

Not yet recruiting

A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Celgene

Not yet recruiting

A Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibitor (Itraconazole) and Inducer (Rifampin) on the Drug Levels of Golcadomide (BMS-986369) in Healthy Participants

Healthy Volunteers

United States
Byondis B.V.

Not yet recruiting

Safety, Pharmacokinetics, and Preliminary Efficacy of BYON4413 in Acute Myeloid Leukemia and Myelodysplastic Neoplasms.

Relapsed / Refractory AML | Relapsed / Refractory MDS
Zhejiang Hanmai Pharmaceutical Technology Co.,...

Not yet recruiting

Multiple-Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of YJ001 for Spray Use in Patients With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain

United States
Peking University Third Hospital

Recruiting

Effect of Oral D-mannose Tablets on Pharmacokinetics of Dabigatranate in Healthy Adults

Health

China
Yuhan Corporation

Not yet recruiting

Bioequivalence Study Between YHP2205 and YHR2401 in Healthy Volunteers

Healthy Volunteers
Shenzhen NewDEL Biotech, Co., Ltd
Shenzhen Innovation Center for Small Molecule Drug Discovery Co., Ltd.

Not yet recruiting

A Study to Evaluate Safety, Tolerability and Pharmacokinetic of ND-003 Tablets in Healthy Adults

Healthy
Changchun BCHT Biotechnology Co.
The First Affiliated Hospital of Yunnan University of Traditional Chinese... and other collaborators

Not yet recruiting

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of the Fully Human Anti-tetanus Toxin Monoclonal Antibody A82 / B86 Injection Combination Formulation

Clostridium Tetanus
AdjuTec Pharma AS
CTC Clinical Trial Consultants AB

Not yet recruiting

A First-in-human Trial to Evaluate Safety, Tolerability, and Pharmacokinetics of APC148 in Healthy Adults

Healthy Subjects

Sweden
Jiaxing AnDiCon Biotech Co.,Ltd

Recruiting

Study of Pharmacokinetics and Metabolism on [(14)C]ADC189

Pharmacokinetics | Metabolism

China
Altria Client Services LLC
Celerion

Recruiting

Pharmacokinetic and Subjective Effects of Heated Tobacco Products

Tobacco Use

United States
AstraZeneca

Not yet recruiting

A Study to Investigate the Pharmacokinetics of Baxdrostat When Given Alone and in Combination With Itraconazole in Healthy Participants

Healthy Participants
Hanmi Pharmaceutical Company Limited

Not yet recruiting

A Study to Evaluate the Pharmacokinetics and Safety Between HCP2303 and Co-administration of Each Component in Healthy Volunteers Under Fed Conditions

Healthy

Korea, Republic of
ImmunoRx Pharma Inc.

Recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics Following Intravenous Administration of IRX-010 in Healthy Participants

Healthy Participants

Netherlands
GlaxoSmithKline

Not yet recruiting

A Study to Investigate the Pharmacokinetics of a Combined Oral Contraceptive When Given Alone and in Combination With GSK3036656 in Female Participants of Non-childbearing Potential Aged 18 to 65 Years of Age

Tuberculosis

Spain
Ferrer Internacional S.A.

Not yet recruiting

A Study to Assess the Efficacy, Safety, and Pharmacokinetics of FNP-223 to Slow Progression of Progressive Supranuclear Palsy (PSP)

Progressive Supranuclear Palsy
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Effect of Verapamil Tablets on the Pharmacokinetic of HRS-1893 Tablets in Healthy Subjects

Obstructive Hypertrophic Cardiomyopathy
Jasper Therapeutics, Inc.

Recruiting

A Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients With Chronic Inducible Urticaria (CIndU) Who Remain Symptomatic Despite Treatment With H1- Antihistamines (SPOTLIGHT)

Chronic Inducible Urticaria

Germany
InnoCare Pharma Inc.

Not yet recruiting

Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ICP-248 in Mature B-cell Malignancies

Mature B-cell Malignancies
James J. Peters Veterans Affairs Medical Center

Recruiting

Transdermal Administration by a Novel Wireless Iontophoresis Device

Constipation | Spinal Cord Injuries | Neurogenic Bowel | Fecal Incontinence

United States
Bristol-Myers Squibb

Not yet recruiting

A Study to Assess the Drug Levels of Repotrectinib in Healthy Participants and Participants With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
OncoC4, Inc.

Not yet recruiting

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

Advanced Solid Tumor

United States
PegBio Co., Ltd.

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PB-119 Injection in Chinese Obese Subjects

Obesity
Equilibra Bioscience LLC

Not yet recruiting

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SR604 in Two Participants Groups (Part A: Healthy Participants, and Part B: Participants With Hemophilia A or Hemophilia B)

Hemophilia A | Hemophilia B | Healthy Participants
Samsung Bioepis Co., Ltd.

Recruiting

A Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity Between SB27 and Keytruda in Subjects With Metastatic Non-squamous Non-small Cell Lung Cancer

Non-small Cell Lung Cancer Stage IV

Georgia, India, Romania, Spain
Tasly Pharmaceutical Group Co., Ltd

Not yet recruiting

Pharmacokinetic and Pharmacodynamic of Jia Shen Tablets in Chronic Heart Failure

Heart Failure

China
Hanmi Pharmaceutical Company Limited

Not yet recruiting

A Study to Evaluate the Pharmacokinetics and Safety Between HCP2303 and Co-administration of Each Component in Healthy Volunteers

Healthy

Korea, Republic of
Vertex Pharmaceuticals Incorporated

Not yet recruiting

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Chulalongkorn University

Not yet recruiting

Pharmacokinetics of Drospirenone Only Pills: A Pre- and Post-Bariatric Surgery Study

Contraception

Thailand
Pontificia Universidad Catolica de Chile

Not yet recruiting

Characterization of the Temporal Profile of the Anti-nociceptive Effect of Ketamine Bolus Measured With ANI (Keta-ANI)

Analgesia | Ketamine | Pharmacokinetic

Chile
Bio-Thera Solutions

Not yet recruiting

A Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetic Characteristics, and Preliminary Efficacy of the Combination of BAT8008 With BAT1308 in Patients With Advanced Solid Tumors

Advanced Solid Tumors
BeiGene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035

Autoimmune Diseases | Healthy Volunteers | Healthy Subjects | Healthy Participants | Healthy Adult Participants
Valenta Pharm JSC

Recruiting

Pharmacokinetics and Bioequivalence of Doxylamine+Pyridoxine and Diclectin

Nausea

Russian Federation
Handok Inc.

Not yet recruiting

Pharmacokinetics of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers

Healthy Volunteers
University Hospital, Grenoble

Not yet recruiting

Pharmacokinetics and Modelling of Beta-Lactam in ECMO-VA Patients (KAMELOT)

Infections | Cardiac Arrest | Cardiogenic Shock | Extracorporeal Membrane Oxygenation Complication | Post-cardiac Surgery

France
Foresee Pharmaceuticals Co., Ltd.
InClin, Inc.

Not yet recruiting

Safety, Tolerability, and Pharmacokinetics, of Single and Multiple Ascending Doses of FP-020 in Healthy Adult Volunteers

Healthy

Australia
AbbVie

Not yet recruiting

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

Crohn's Disease
Biocad

Recruiting

Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (LEVENTA)

Axial Spondyloarthritis

Russian Federation

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