Search clinical trials for: plasma concentrations

Total 7722 results

University Hospital Center of Martinique
University Hospital, Limoges; Reims University Hospital; BioGaia AB; Regional Health... and other collaborators

Not yet recruiting

Effects of Probiotic Oral Intake on Plasma Chlordecone (Kepone) Concentrations in Individuals Environmentally Exposed to Pesticide in Martinique. (CHLOR-DETOX)

Chlordecone (Kepone) Toxicity

Martinique
University Hospital, Caen

Not yet recruiting

Relation Between Psychoactive Drugs Overdosage and Severity of Falls in Elderly People (MEDIFALL)

Fall
National Nutrition and Food Technology Institute

Not yet recruiting

The Effects of an Anti-inflammatory Diet With or Without Curcumin Supplementation on Anthropometric Measurements, Concentrations of Thyroid Hormones, Anti-TPO, and Systemic Inflammation in Plasma and NFK-B in Peripheral Blood Mononuclear Cells in Patients With Hashimato

Hypothyroidism | Thyroid Diseases | Hashimoto Disease

Iran, Islamic Republic of
Hospices Civils de Lyon

Recruiting

Hypovitaminosis C Prevalence and Risk Factors in an Acute Geriatric Unit (HYPO-VIT-C)

Deficiency, Vitamin C

France
University of Turin, Italy

Recruiting

Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery

Postoperative Pain | Regional Anesthesia Morbidity | Local Anesthetic Toxicity

Italy
Centre Hospitalier Universitaire, Amiens

Recruiting

Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery (LARA)

Analgesia | Thoracic Epidural Analgesia | Lidocaine Adverse Reaction | Abdominal Surgery by Laparotomy

France
Assiut University

Not yet recruiting

Serum Rennin Kinetics Versus Serum Lactate Kinetics as Predictors of Mortality in Septic Shock Patients

Septic Shock
The First Affiliated Hospital of Soochow University
Shandong Provincial Hospital; Qingdao Municipal Hospital; Central South University and other collaborators

Not yet recruiting

Optimal Adalimumab Plasma Concentrations in Ankylosing Spondylitis Patients

Ankylosing Spondylitis

China
Bexion Pharmaceuticals, Inc.
CTI Clinical Trial and Consulting Services

Recruiting

A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) (KONQUER)

Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant

United States
Baylor College of Medicine

Recruiting

Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population

Anesthesia, Local

United States
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
National Institute of Diabetes and Digestive and...

Recruiting

Urinary Vitamin C Loss in Diabetic Subjects

Diabetes

United States
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Hartford Hospital
Shionogi Inc.

Active, not recruiting

Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy

Pharmacokinetics

United States
St. Boniface Hospital
Agriculture and Agri-Food Canada

Active, not recruiting

Flax Muffins and Cholesterol Lowering

Above Optimal Plasma LDL Concentrations

Canada
Seoul National University Hospital

Completed

Plasma Ropivacaine Concentrations After Sciatic Nerve Block in Patients With Chronic Kidney Disease

Regional Anesthesia Morbidity | Local Anesthetic Drug Adverse Reaction

Korea, Republic of
BIO-CAT, Inc.
McGill University

Completed

Effects of Microbial Protease Supplementation on Postprandial Plasma Amino Acid Concentrations and Appetite

Appetitive Behavior | Gastrointestinal Health | Digestive Health

Canada
Centre Hospitalier Universitaire de Saint Etienne

Completed

Normal Values of Parameters of Thrombin Generation in Function of Different Tissue Factor Concentrations (NUAGE)

Healthy Volunteers

France
Hospital Universitari de Bellvitge
Baxter Healthcare Corporation

Completed

Antibiotic Plasma Concentrations During Continuous Renal Replacement Therapy With a High Adsorption Membrane (oXiris®)

Sepsis | Acute Kidney Injury | Hemodiafiltration

Spain
Rempex Pharmaceuticals (a wholly owned subsidiary...
Innovative Medicines Initiative; Universitätsklinikum Köln

Withdrawn

Safety and PK Trial Evaluating the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations of Minocin IV

Normal Healthy Volunteers

Austria
Pipeline Therapeutics, Inc.

Completed

PET Study to Determine the Relationship Between Plasma Concentrations and Muscarinic Type 1 Receptor (M1AChR) Occupancy of PIPE-307 in Healthy Volunteers

Multiple Sclerosis

United Kingdom
Purdue University

Completed

Protein Source on Plasma Amino Acid Concentrations In Older Adults (S55)

Protein Deposition

United States
University Hospital, Bordeaux

Completed

Relationship Between Pharmacokinetics and Safety of Vismodegib - OPTIVISMO-1 (OPTIVISMO-1)

Locally Advanced Basal Cell Carcinoma | Metastatic Basal Cell Carcinoma

France
Damascus University
Hama University

Completed

The Effect of Autologous Platelet Concentrations on Orthodontic Treatment Time

Class II Division 1 Malocclusion

Syrian Arab Republic
Liegang Liu

Completed

Associations of Plasma Vanadium Concentrations With Gestational Diabetes Mellitus

Gestational Diabetes
Hôpital Charles Foix
Assistance Publique - Hôpitaux de Paris; University of Paris 5 - Rene Descartes and other collaborators

Completed

New Oral Direct Anticoagulants in Patients 80 Years Old and Over : a Population Pharmacokinetics Study (ADAGE)

Atrial Fibrillation

France
University Hospital, Clermont-Ferrand

Completed

Plasmatic Concentrations of Propofol and Remifentanil in Obese and Non Obese Patients. (COCOPOPONO)

Obesity | General Anesthesia

France
Novartis Pharmaceuticals

Terminated

Study of Nilotinib in Ph+ CML-CP Patients With Low Imatinib Trough Plasma Concentrations (MACS1148)

CML | Philadelphia Chromosome Positive (Ph+) | Chronic Myelogenous Leukemia Chronic Phase(CML-CP) Patients With Low Imatinib Trough Levels

United States
Hospices Civils de Lyon

Completed

Micronutrient Status Involved in Immunity in Elderly Patients With COVID-19 (MicroCovAging)

Covid19

France
Spero Therapeutics
Clinartis

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Healthy Volunteers

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Phase 1, Open-Label Study of Latanoprost Acid Plasma Concentrations in Pediatric and Adult Glaucoma Patients Treated With Latanoprost.

Ocular Hypertension | Glaucoma

United States, Spain, Italy, Denmark, Portugal, South Africa
McGill University

Completed

The Effects of Cricket- and Beef-derived Protein on Plasma Amino Acid Concentrations and Appetite Responses

Appetitive Behavior | Aminoacidemia

Canada
University Hospital, Toulouse

Completed

Association Between Side Effects Occurrence and Concentrations of Ibrutinib and Idelalisib (PK-E3I)

Hematological Malignancies

France
Radboud University Medical Center
University Medical Center Groningen; Maastricht University Medical Center; UMC... and other collaborators

Completed

Evaluation of RIBAvirin Plasma COncentrations in Patients With Chronic Hepatitis C Infection Routinely Treated With Modern DAA Regimens (RIBACOP)

Hepatitis C | HCV Coinfection

Netherlands
Pfizer

Completed

A Study Of PF-04447943 Compared To Placebo In Subjects With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

United States, Canada, Chile, Czechia
Teva Pharmaceuticals USA

Withdrawn

An Open-Label, Single-Center Study to Evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc at Steady State Following Once-daily Administration of CASSIPA® in Opioid Dependent Subjects.

Evaluation of QTc Interval
Purdue University

Completed

Protein Source on Plasma Amino Acid Concentrations

Protein Deposition

United States
University Hospital, Clermont-Ferrand

Unknown

Plasma Concentrations of Amoxicillin Administered in High-doses During the First Week of Treatment (MAX-AMOX) (MAX-AMOX)

Infection, Bacterial

France
University Hospital, Bordeaux

Completed

Correlation Between Sorafenib Plasma Concentrations, Toxicity and Disease Control Rate in Patients Treated by Sorafenib for Hepatocellular Carcinoma (ACTES)

Hepatocellular Carcinoma (HCC)

France
Mahidol University

Completed

Plasma Concentrations of Prophylactic Cefazolin in Pediatric Patients Undergoing Cardiac Surgery With CPB

Surgical Site Infection

Thailand
Xuzhou Medical University

Completed

POCD: Correlations With the Gene Polymorphism and the Concentrations of Plasma Homocysteine, Folic Acid and Vitamin B12.

Postoperative Cognitive Dysfunction

China
University Women's Hospital Tübingen

Unknown

Plasma Concentrations of Calcium, Phosphate, FGF23, Klotho, 25 (OH) D3 and 1,25 (OH) 2D3 From Patients Who Wants to Have Children

Infertility, Female

Germany
Karolinska University Hospital

Completed

Meropenem and Piperacillin Plasma Concentrations During CRRT (ABC2)

Sepsis | Hemolysis | Renal Replacement Therapy | Infection | Antibiotic

Sweden
University Hospital, Limoges

Completed

Description of the Evolution of Plasma and Urinary Concentrations of Iohexol in a Cirrhotic Patient Population (DFG HEP)

Cirrhosis Renal

France
King's College London

Completed

Palmitic Acid in the Sn-2 Position of Triacylglycerols and Postprandial Lipemia

Healthy Men | Raised Fasting Plasma Triacylglycerol Concentrations

United Kingdom
Boehringer Ingelheim

Completed

Study to Investigate the Pharmacokinetics (PK) and Pharmacodynamics (PD) of Idarucizumab in Chinese Healthy Male and Female Volunteers Who Had Taken Dabigatran Etexilate and Whose Plasma Concentrations of Dabigatran Were at or Close to Steady State

Healthy Volunteers

China
University Hospital, Grenoble

Completed

Influence of a Combined Pharmacogenetic Score on Through Plasma Voriconazole Concentrations in Haematological Patients (VORIGENE)

Invasive Aspergillosis | Voriconazole | Haematological Cancer Patients

France
Alison Gernand
Penn State University

Completed

Cyclic Variation in Micronutrient Concentrations and Plasma Volume

Menstrual Cycle | Plasma Volume | Micronutrients

United States
The Cleveland Clinic

Completed

Vasopressin Plasma Concentrations in Patients Receiving Exogenous Vasopressin Infusion for Septic Shock

Septic Shock

United States
Centre Hospitalier Universitaire de Nīmes

Completed

Free DNA and Nucleosome Concentrations in Pathological Pregnancies

Venous Thrombosis | Pregnancy | Eclampsia | Pre-Eclampsia | Hypertension, Pregnancy-Induced | Pulmonary Embolism | HELLP Syndrome | Fetal Death | Placental Insufficiency

France

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