Search clinical trials for: rearranged during transfection

Total 11367 results

University of Milano Bicocca

Recruiting

Prospective Study on Resistance-associated Mutations in Metastatic Lung Cancer (MUT-ONC)

Lung Cancer

Italy
Hoffmann-La Roche

Recruiting

A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive or Rearranged During Transfection (RET)-Positive Cancer

Neoplasms

Italy, France, Turkey, Korea, Republic of, Spain, China, United States, Hong Kong, Russian Federation, Poland
Hoffmann-La Roche

Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW)

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Endocrine System Diseases | Gastrointestinal Neoplasms | Neoplasms, Germ Cell and Embryonal | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Respiratory Tract... and other conditions

France, Spain, United States, Korea, Republic of, United Kingdom, Taiwan, China, Belgium, Singapore, Netherlands, Germany, Italy, Hong Kong
Boston Pharmaceuticals

Completed

Safety, Efficacy, and Tolerability of BOS172738 in Patients With Advanced Rearranged During Transfection (RET) Gene-Altered Tumors

Advanced Nonhaematologic Malignancies

United States, Korea, Republic of, Taiwan, France, Hong Kong, Belgium, Spain
Loxo Oncology, Inc.
Eli Lilly and Company

Available

Expanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) Activation

Breast Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Colon Cancer | Medullary Thyroid Cancer | Papillary Thyroid Cancer | Other Solid Tumors With Evidence of Activating RET Alteration

Spain, United States, Australia, France, Germany, Israel, Italy, Japan, New Zealand, Poland, Singapore, Switzerland
GlaxoSmithKline

Completed

A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers

Irritable Bowel Syndrome

Australia
GlaxoSmithKline

Completed

A Phase 1, Randomized, Placebo-Controlled, Ascending Cohort, Dose Escalation Study in Normal Healthy Volunteers

Irritable Bowel Syndrome

Australia
GlaxoSmithKline

Completed

A Phase I, Randomized, Placebo-controlled, Double Blind, Repeat Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Gastrointestinal Transit Time and Pharmacodynamic Biomarkers of GSK3179106 in Normal Subjects

Irritable Bowel Syndrome

Australia
Lumos Labs, Inc.

Not yet recruiting

Task Atlas: Study to Develop a Task Atlas of Brain Recruitment During a Digital Game-based Program

Healthy Adults

United States
Bezmialem Vakif University

Not yet recruiting

Nomogram for Prediction of Alveolo-arterial Gradient During One-lung Ventilation

One-lung Ventilation

Turkey
Aretaieion University Hospital

Recruiting

Chloroprocaine 1% Versus Ropivacaine 0,75% During Cesarean Section (annie-mariana)

Cesarean Section | Local Anesthetic

Greece
Seventh Medical Center of PLA General Hospital
Guangdong Provincial People's Hospital; Henan Provincial People's Hospital; People... and other collaborators

Not yet recruiting

Prone Position During ECMO in Pediatric Patients With Severe ARDS (PEPAD)

Extracorporeal Membrane Oxygenation | Pediatric Acute Respiratory Distress Syndrome

China
Shanghai Children's Medical Center

Not yet recruiting

Comparative Study on the Efficacy and Safety of Ondansetron Oral Membrane for the Prevention of Vomiting During Moderate Hypoemetic Chemotherapy (Ondansetron)

To Analyze and Compare the Efficacy and Safety of Ondansetron and Tablet for the Prevention of Moderate and Hypoemetic Chemotherapy
Ain Shams University

Not yet recruiting

A Non Invasive Confirmatory Sign for Correct Epidural Catheter Placement During Normal Vaginal Delivery

Normal Delivery Pain
University of Rochester

Not yet recruiting

TENS Analgesia During Outpatient Urethral Bulking for Stress Urinary Incontinence. (TENSUB)

Pain | Urinary Incontinence | Urinary Incontinence,Stress | Pain Acute | Stress Incontinence Female

United States
Ankara Yildirim Beyazıt University

Not yet recruiting

Coolsense and Buzzy Use on Pain Score and Anxiety Level During Insulin Injection Application

Pain | Type 1 Diabetes Mellitus | Nurse's Role | Injection Fear | Pediatric Disease | Injection Site Coldness
Mersin University

Not yet recruiting

Effect of Ball Squeezing and Adhesive Remover Use on Pain and Fear in Children Aged 6-9 Years During the Removal of Peripheral Intravenous Cannula

Fear of Pain | Procedural Pain

Turkey
Mersin University

Not yet recruiting

The Effect of Watching Cartoons and Playing Games as Distraction Method During Peripheral Intravenous Cannula Placement on Pain and Fear in Children Aged 6-9 Years

Fear of Pain | Procedural Pain

Turkey
Centre Francois Baclesse
Cureety

Recruiting

Benefit of Adding Cureety TechCare Telemonitoring to Usual Care During Injectable Anticancer Treatment (OPTIMACURE)

Adult Patients Initiating Injectable Anticancer

France
Parc de Salut Mar

Recruiting

Comparative Study of the Surface Electrocardiogram Signals During the Implantation of Conduction System Pacing Devices

Pacemaker DDD | Conduction Disorder

Spain
Azienda Ospedaliero Universitaria Maggiore della...

Not yet recruiting

Monitoring of Lung Ventilation Through Electrical Impedance Tomography During Pediatric Surgery (VentiPed)

Surgery | Ventilator Lung | Pediatric
Samuel Lunenfeld Research Institute, Mount Sinai...

Not yet recruiting

The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During Routine Cesarean Delivery (PAS-EDU-RCD)

Well-Being, Psychological

Canada
Samuel Lunenfeld Research Institute, Mount Sinai...

Not yet recruiting

The Patient AS EDUcator in Anesthesia: Exploring the Patients' and Providers' Experience During Neuraxial Labour Analgesia (PAS-EDU-NLA)

Well-Being, Psychological

Canada
University Hospital, Basel, Switzerland
Research Center for Clinical Neuroimmunology and Neuroscience Basel

Not yet recruiting

Implementation of Liquid Biopsies During Routine Clinical Care in Patients With Advanced Malignancies (LIQPLAT) (LIQPLAT)

Advanced Solid Tumor
Tribhuvan University Teaching Hospital, Institute...

Not yet recruiting

Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia

Visceral Pain
Kliniken Essen-Mitte
Karl and Veronica Carstens Foundation

Not yet recruiting

Auricular Acupuncture and Hot Flashes During Adjuvant Endocrine Therapy (OhrHit)

Hot Flashes
University of Erlangen-Nürnberg Medical School

Not yet recruiting

App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy

Squamous Cell Carcinoma of Head and Neck

Germany
Beni-Suef University

Recruiting

The Sedative Effects of Dexmedetomidine VS Propofol During Peribulbar Anesthesia in Patients Undergoing Vitrectomy Surgery

Satisfaction | Patient

Egypt
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric Study (MUPIPHARM)

Healthy | Staphylococcus Aureus Infection

France
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Recruiting

Lysine Requirements During Lactation

Lactation | Breastfeeding | Breastfeeding, Exclusive

Canada
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
Eckhard Mauermann

Recruiting

A COMPARISON OF LEFT VENTRICULAR FUNCTION IN THE APICAL 4 CHAMBER AND SUBCOSTAL 4 CHAMBER TTE VIEWS IN THE PERIOPERATIVE SETTING

Cardiac Functional Disturbances During Surgery

Switzerland
Beijing Tiantan Hospital
West China Hospital; The First Affiliated Hospital of Zhengzhou University; Capital... and other collaborators

Recruiting

Evaluate the Effectiveness and Safety of Raman IVD Analyzer in the Molecular Diagnosis of Gliomas During Surgery

Glioma

China
Essity Hygiene and Health AB

Not yet recruiting

Reducing Skin Surface pH During Skin Occlusion: Changes to Skin Microbiome and Skin Parameters

Incontinence-associated Dermatitis

Sweden
University of Sao Paulo General Hospital
Samsung Eletrônica da Amazônia Ltda; Academic Research Organization of Instituto...

Recruiting

Assessment of Smartwatch SAMSUNG to Monitor Sleep Quality: an Observational Prospective Study - SleepEx2 Protocol (SLEEP-EX2)

Insomnia | Sleep Initiation and Maintenance Disorders | Sleep | Health Status | Wearable Electronic Devices

Brazil
Yonsei University

Recruiting

Comparison of Remimazolam and Propofol Effect on Oxygen Reserve During Endoscopic Retrograde Cholangiopancreatography

Hepatobiiliary Diseases Requiring Endoscopic Retrograde Cholangiopancreatography

Korea, Republic of
University Hospital, Montpellier

Not yet recruiting

Plasma Biomarkers of Muscle Metabolism During Exercise to the Assessment of Insulin Resistance in CKD Dialysis Patients (KREBSome-IRC)

Metabolic Syndrome | Dialysis; Complications

France
Dokuz Eylul University

Not yet recruiting

Evaluation of the Effects of Different Ventilation Modes Used During Anesthesia Awakening on the Frequency of Postoperative Atelectasis

Atelectasis, Postoperative Pulmonary
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Study of the Evolution of the Expression of the LAMP-2 Protein During the Advance in Age

Aging

France
Damascus University

Recruiting

Re-infusion of Unwashed Shed Blood During Off-pump Surgery

Coronary Artery Disease | Cardiovascular Complication | Blood Transfusion Complication

Syrian Arab Republic
University Hospital, Montpellier

Not yet recruiting

Evaluation of the Absence of Intraoperative Bladder Catheterization in Case of Planned Cesarean Section (C2S)

Pregnant Women | Cesarean Section

France
Nova Scotia Health Authority

Not yet recruiting

Evaluation of an Anxiety Reduction Tool During Thyroid and Prostate Biopsy Procedures

Anxiety State
Eduardo Schiffer
University Hospital, Geneva; Insel Gruppe AG, University Hospital Bern

Not yet recruiting

Platelet Count and Function After Usage of Two Different Cell Saver Devices During Liver Transplant Surgery (PLFLTS)

Liver Transplant | Hemorrhage, Surgical

Switzerland
KK Women's and Children's Hospital

Not yet recruiting

Continuous Glucose Monitoring Glycemic cHAracterization During Pregnancy (I-CHAP)

Glucose Metabolism Disorders | Gestational Diabetes | Metabolic Disease
University of Leicester
University Hospitals, Leicester; British Heart Foundation

Not yet recruiting

The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke (LACUNAR_CA)

Lacunar Stroke

United Kingdom
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Efficacy of Intraoperative Use of 20% Albumin Combined With Ringer Lactate Versus Ringer Lactate During Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy: Protocol for a Randomized Open-label Clinical Trial (ALBUCHIP)

Postoperative Complications | Peritoneal Neoplasms | Fluid Therapy | Hyperthermic Intraperitoneal Chemotherapy | Intraoperative Care | Cytoreduction Surgical Procedures | Albumin Administration
University of Seville

Not yet recruiting

Pain and Anxiety During Local Block

Pain | Anesthesia, Local | Anxiety
University of Padova

Not yet recruiting

Correlation Between qNOX and Analgesia Nociception Index (ANI) Values During General Anesthesia (ANI)

Analgesia

Italy
University of Padova

Not yet recruiting

Describe Relations Between qCON and qNOX Indicies During Propofol-Remifentanil General Anesthesia

Anesthesia Brain Monitoring

Italy
NYU Langone Health

Not yet recruiting

Implementing Virtual Reality (VR) to Reduce Sedation

Sedative During Endoscopy

United States

Search clinical trials for: rearranged during transfection

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