Search clinical trials for: thrombopoietin mimetic

Total 176 results

University Hospital, Toulouse
French network for inherited hemorragic diseases; National Reference Centre...

Recruiting

Perioperative Eltrombopag in Patients With Inherited Thrombocytopenia (ELPOT)

Thrombocytopenia

France
AO GENERIUM

Enrolling by invitation

Study of the Safety and Immunogenicity of Long-term GNR-069 Therapy in ITP Patients

Idiopathic Thrombocytopenic Purpura

Russian Federation
Safaa AA Khaled
Assiut University

Completed

Combination of Thrombopoietin Mimetic and Immunosuppressive Therapy in Aplastic Anaemia

Aplastic Anemia

Egypt
GlaxoSmithKline

Completed

Oral LGD-4665 Versus Placebo in Adults With Immune Thrombocytopenic Purpura (ITP) for 6 Weeks Plus Open Treatment Continuation

Immune Thrombocytopenic Purpura

United States
Stanford University
Weill Medical College of Cornell University

Completed

Genome-Wide Gene Expression Profiling of Patients With ITP Receiving Thrombopoietin Mimetics

Immune Thrombocytopenia

United States
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura

China
Beijing Dongfang Biotech Co., Ltd.

Not yet recruiting

A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Placebo in T2DM Patients

Type 2 Diabetes Mellitus

China
Kinnov Therapeutics

Not yet recruiting

A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine

Alcohol Use Disorder
Assiut University
Association for Training, Education, and Research in Hematology, Immunology...

Not yet recruiting

Thrombopoietin Agonists in Patients With Idiopathic Thrombocytopenic Purpura

ITP - Immune Thrombocytopenia
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III... and other conditions
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia (AIHA ITP CIN)

Myelodysplastic Syndromes | Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Cold Agglutinin Disease | Autoimmune Neutropenia | Chronic Idiopathic Neutropenia

Italy
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine for Poor Graft Function Post Allo-HSCT

Poor Graft Function
Assiut University

Not yet recruiting

Safety of Oral Thrombopoietin Receptor Agonist in Pediatric Chronic ITP

Thrombopoietin Receptor Agonist
Beijing Tsinghua Chang Gung Hospital

Not yet recruiting

Effect of Azilsartan on Atrial Fibrillation in Patients With Hypertension (AZAF)

Hypertension | Atrial Fibrillation

China
Xiyuan Hospital of China Academy of Chinese Medical...
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine and other collaborators

Not yet recruiting

Efficacy and Safety of Linggui Yangyuan Paste in Patients With Male Infertility

Male Infertility | Asthenozoospermia | Oligoasthenozoospermia
Chen Qian

Recruiting

Clinical Study of Cang Ai Volatile Oil (CAVO) on Mild to Moderate Depression in Children and Adolescents

Depression

China
Hanny Al-Samkari, MD
Swedish Orphan Biovitrum

Recruiting

Avatrombopag vs. Placebo for CIT in GI Malignancies (ACT-GI)

Gastrointestinal Neoplasms | Gastrointestinal Cancer | Chemotherapy-Induced Thrombocytopenia

United States
Jiangsu Famous Medical Technology Co., Ltd.
Jiangsu Province Hospital of Traditional Chinese Medicine

Recruiting

Xian-Lian-Jie-Du Optimization Decoction as an Adjuvant Treatment for Prevention of Recurrence of Colon Cancer

Colon Cancer

China
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine and Umbilical Cord Blood for Poor Graft Function Post Allo-HSCT

Poor Graft Function
Hospital Universitari de Bellvitge

Recruiting

Drug-Eluting Balloons vs Mimetic Stents for Popliteal Artery Disease

Popliteal Arterial Stenosis

Spain
Peking University People's Hospital

Not yet recruiting

IVIg Plus Low Dose rhTPO for ITP in Pregnancy

Pregnancy Related | Immune Thrombocytopenia
University Medical Center Groningen

Recruiting

Evaluation of the 18F-PSMA Positron Emission Tomography (PET)/CT in Patients With Medullary Thyroid Cancer (MIMETIC)

Medullary Thyroid Cancer | Thyroid Cancer, Medullary | Medullary Thyroid Carcinoma | Thyroid Carcinoma, Medullary

Netherlands
Sichuan Clover Biopharmaceuticals, Inc.

Recruiting

A Clinical Trial Evaluating SCB-219M in in Chemotherapy-induced Thrombocytopenia (CIT)

Chemotherapy-induced Thrombocytopenia (CIT)

China
The First Affiliated Hospital of Dalian Medical...
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Chinese... and other collaborators

Recruiting

Efficacy and Safety of rhTPO's Prophylactic Treatment of CTIT in Patients With High Risk of Cardiac Injury (Circular)

Cancer Treatment Induced Thrombocytopenia

China
Peking University People's Hospital
Qilu Hospital of Shandong University; Beijing Tongren Hospital; Beijing Hospital and other collaborators

Not yet recruiting

Zanubrutinib and Eltrombopag as Second-line Treatment in Adults With Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China
The First Affiliated Hospital of Zhengzhou University
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Clinical Study of Herombopag in Tumors-associated Thrombocytopenia

Tumor Therapy-related Thrombocytopenia
Peking University People's Hospital

Recruiting

The Combination of Prednisone and Recombinant Human Thrombopoietin for Treatment of Immune Thrombocytopenia in Pregnancy

Immune Thrombocytopenia

China
Yin Jie

Recruiting

Herombopag + rhTPO in Severe Immune Thrombocytopenia

Immune Thrombocytopenia

China
Nanfang Hospital of Southern Medical University
The Third Affiliated Hospital of Southern Medical University; The Second People... and other collaborators

Not yet recruiting

Effects of Recombinant Human Thrombopoietin on Platelet Levels in ICU Patients

Pneumonia | Thrombocytopenia
Shenyang Sunshine Pharmaceutical Co., LTD.

Not yet recruiting

A Phase Ib Clinical Study for rhTPO in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease

Thrombocytopenia | Liver Disease Chronic

China
Angion Biomedica Corp
Nucleus Network Ltd

Not yet recruiting

Study to Evaluate the Pharmacokinetics of ANG-3777 in Hemodialysis Subjects

Hemodialysis

United States
Angion Biomedica Corp
Quotient Sciences

Recruiting

A Study to Assess the Absorption, Metabolism and Excretion of [14C]-ANG-3777

Healthy

United Kingdom
Peking University People's Hospital

Not yet recruiting

A Study of Switching Avatrombopag and Rh-TPO in ITP

Corticosteroid-resistant or Relapsed ITP
Angion Biomedica Corp
Quotient Sciences

Not yet recruiting

Study Developed to Evaluate the Effect of ANG-3777 on QT/QTc Interval

Healthy Volunteer

United States
University Hospital, Bordeaux
Ministry for Health and Solidarity, France

Recruiting

Contribution of Anti-platelet Antibodies Identified With MAIPA Assay in the Demonstration of the Auto-immune Character of a Thrombocytopenia at Diagnosis (APAT)

Thrombocytopenia | Immune Thrombocytopenia | Myelodysplasia

France
Shanghai Pulmonary Hospital, Shanghai, China

Not yet recruiting

Adjuvant Toripalimab Plus Chemotherapy for EGFR/ALK Mutation Negative Stage II-IIIB(N2) NSCLC (LungMate-008)

Non Small Cell Lung Cancer
K-Group Alpha, Inc., a wholly owned subsidiary...

Recruiting

Phase 1 First in Human Study of ZN-d5 as a Single Agent

Acute Myeloid Leukemia | Non Hodgkin Lymphoma

Croatia, Australia, Bulgaria, Korea, Republic of, Ukraine, Poland, Spain
ID3 Medical

Recruiting

A Study Evaluating the Endovascular Treatment of Subjects With Stenotic or Restenotic Lesions of the Common Femoral Artery With the Supera Vascular Mimetic Implant Compared to Surgical Common Femoral Artery Endarterectomy (SUPERSURG-RCT)

Peripheral Arterial Disease

Belgium, Netherlands, Poland
Ruilan Wang
Changhai Hospital; Shanghai Jiao Tong University School of Medicine; Shanghai... and other collaborators

Recruiting

The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia (RESCUE)

Sepsis | Thrombocytopenia

China
Centers for Disease Control and Prevention
Ministry of Health, Liberia

Completed

Efficacy of Artesunate-amodiaquine and Artemether-lumefantrine for Treatment of Plasmodium Falciparum Malaria in Liberia

Malaria | Plasmodium Falciparum | Uncomplicated Malaria

Liberia
AO GENERIUM

Completed

Comparative Study of Clinical Efficacy and Safety of GNR-069 and Nplate in Patients With ITP

Idiopathic Thrombocytopenic Purpura

Russian Federation
Institute of Hematology & Blood Diseases Hospital...
Xijing Hospital; Xi'an Central Hospital; The Second Hospital of Hebei Medical... and other collaborators

Active, not recruiting

A Randomized Trial Comparing Optimized rhTPO Treatment With Eltrombopag Treatment in Pre-treated ITP Pts (TE-ITP)

Previously Treated Primary Immune Thrombocytopenia

China
Centre Hospitalier Universitaire de Nīmes

Active, not recruiting

Functional Characterization of Thrombopoietin/cMPL Receptor Mutations in Myeloproliferative Neoplasia (MPL - NPM)

Myeloproliferative Disorder

France
Swedish Orphan Biovitrum

Active, not recruiting

An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP (ADOPT)

Immune Thrombocytopenia | ITP

Croatia, Czechia, Germany, Italy, Netherlands, Norway, Spain, Switzerland, United Kingdom
Novartis Pharmaceuticals

Completed

A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP (XPAG-ITP)

Immune Thrombocytopenia (ITP)

Germany
University Children's Hospital Basel
Novartis Pharmaceuticals; Stiftung zur Förderung medizinischer und biologischer... and other collaborators

Active, not recruiting

Immunomodulation With Eltrombopag in ITP (iROM2)

Primary Immune Thrombocytopenia (ITP)

Switzerland
Protagonist Therapeutics, Inc.

Active, not recruiting

Hepcidin Mimetic in Patients With Polycythemia Vera (REVIVE)

Polycythemia Vera

United States, India
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Thrombocytopenia

United States
Galera Therapeutics, Inc.

Completed

ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients

Oral Mucositis

United States, Puerto Rico, Canada
Anjali Sharathkumar
Amgen

Active, not recruiting

TPO-Mimetic Use in Children for Hematopoietic Failure

Thrombocytopenia | Bone Marrow Failure Disorders | Aplastic Anemia | Refractory Cytopenia of Childhood | Myelodysplastic Syndrome(MDS)

United States

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