Senior Assay Development Scientist - Cell Biology

<h2>Job Overview:</h2><p style="margin: 0px;"><span style="color: #000000;"><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;">Are you a </span></strong><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;">Cell Biologist </span></strong><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;">with experience of Assay Development?</span></strong></span></p><p style="margin: 0px;"><span style="color: #000000;"><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;"> </span></strong></span></p><p style="margin: 0px;"><span style="color: #000000;"><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;">Are you interested in career development opportunities and project management responsibility?</span></strong></span></p><p style="margin: 0px;"><span style="font-size: 12pt; font-family: Arial, sans-serif; color: #000000;"> </span></p><p style="margin: 0px;"><span style="color: #000000;"><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;">Do you want to be a part of the world's leading drug development company?</span></strong></span></p><p style="margin: 0px;"> </p><p style="margin-right: 1.8pt;"><span style="color: #000000;"><span style="font-size: 12pt; font-family: Arial, sans-serif;">Our UK site in York is currently recruiting for a <strong>Senior Assay Development</strong> <strong>Scientist</strong> to join the CMC (Chemistry, Manufacturing Controls) division and will be responsible for the efficient development and optimisation of analytical methods within BioPharm CMC, in accordance with Client requirements and associated protocol and procedures.</span></span></p><p style="margin: 0px;"><span style="color: #000000;"> </span></p><p style="margin: 0px;"><span style="font-size: 12pt; font-family: Arial, sans-serif; color: #000000;">Labcorp Drug Development has helped pharmaceutical and biotech companies develop one-third of all prescription medicines in the market today. Chances are, you or someone you know has benefitted from a medicine or medical device that Labcorp Drug Development helped develop. </span></p><p style="margin: 0px;"><span style="color: #000000;"><em><span style="font-size: 12pt; font-family: Arial, sans-serif;"> </span></em></span></p><p style="margin: 0px;"><span style="color: #000000;"><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;">What Labcorp Drug Development can offer you:</span></strong></span></p><ul><li style="margin-left: 54.0pt;"><span style="font-size: 12pt; font-family: Arial, sans-serif; color: #000000;">Competitive salaries and a comprehensive benefits package including health cover and contributory pension</span></li><li style="margin-left: 54.0pt;"><span style="font-size: 12pt; font-family: Arial, sans-serif; color: #000000;">Unrivalled opportunities to develop a successful career in the scientific industry, utilizing multiple analytical techniques</span></li><li style="margin-left: 54.0pt;"><span style="font-size: 12pt; font-family: Arial, sans-serif; color: #000000;">Unsurpassed career development opportunities, with the ability to develop your management skills</span></li><li style="margin-left: 54.0pt;"><strong><span style="font-size: 12pt; font-family: Arial, sans-serif; color: #000000;">Ability to work with a variety of different clients on wide ranging projects</span></strong></li><li style="margin-left: 54.0pt;"><span style="font-size: 12pt; font-family: Arial, sans-serif; color: #000000;">Opportunity to work in a rapidly expanding and leading edge field</span></li></ul><p style="margin: 0px;"><span style="color: #000000;"><strong><span style="font-size: 12pt; font-family: Arial, sans-serif;">Job responsibilities include:</span></strong></span></p><p style="margin: 0px;"> </p><ul><li><span style="color: #000000;"><span style="font-size: 12pt; font-family: Arial, sans-serif;"><span style="font-size: 11.0pt;">Primarily responsible for the development and establishment of cell-based analytical procedures within BioPharm CMC that demonstrate the biological function of therapeutics</span></span></span></li><li><span style="color: #000000;"><span style="font-size: 12pt; font-family: Arial, sans-serif;"><span style="font-size: 11.0pt;">The individivual is recognised as a </span><span style="font-size: 11.0pt;">Subject Matter Expert (SME) in cell-based methods </span><span style="font-size: 11.0pt;">both internally and externally</span><span style="font-size: 11.0pt;">. Responsible for the scientific conduct and process associated with studies, including review and approval of data and documentation</span></span></span></li><li><span style="color: #000000;"><span style="font-size: 12pt; font-family: Arial, sans-serif;"><span style="font-size: 11.0pt;">Has close and regular liaison with Clients, QC Operations teams, Project Managers , GMP Quality Assurance,</span><span style="font-size: 11.0pt;"> as well as direct reports. </span></span></span></li><li><span style="color: #000000;"><span style="font-size: 12pt; font-family: Arial, sans-serif;"><span style="font-size: 11.0pt;">Represents a direct point of contact</span><span style="font-size: 11.0pt;"> for technical discussion, scientific escalation and</span><span style="font-size: 11.0pt;"> assay troubleshooting</span></span></span></li><li><span style="color: #000000;"><span style="font-size: 12pt; font-family: Arial, sans-serif;"><span style="font-size: 11.0pt;">60% of the time in the laboratory, 40% office based, this is a UK based role with studies being performed both in the UK and the USA</span></span></span></li></ul><p style="margin: 0px;"> </p><h2>Education/Qualifications:</h2><ul><li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Undergraduate degree in Life sciences, or related discipline</span></li><li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Postrgaduate degree in a cell biology related topic</span></li></ul><h2>Experience:</h2><p style="margin: 0in; margin-bottom: .0001pt;"> </p><ul><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Experience in <strong>mammalian cell culture </strong>and cell-based assays (e.g. flow cytometry, reporter-gene cell lines, cytotoxicity)</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Ability to design experiments and studies to address key scientific questions related to the biological activity of complex therapeutics (e.g. antibodies, gene therapies, cell therapies)</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Experience of relative potency assays</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Experience with viral preparation, cell transductions/transfections, and associated work</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Knowledge and skills to use more specialist lab equipment (such as flow cytometers, Biacore, plate readers, ddPCR)</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Experience with standard molecular biology techniques such as primer design, PCR, DNA cloning methods and sequencing analysis</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Ability to write experimental plans, standard operating procedures and reports with meticulous attention to detail</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Advanced experimental design skills (design of experiment, statistical designs)</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Industrial experience in a regulatory environment and p</span><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">roven ability to troubleshoot cell based assays</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Strong team player but also able to work independently with t</span><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">echnical interest and enthusiasm</span></li><li style="margin: 0in 0in .0001pt .5in;"><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Excellent presentation and communication skills</span></li></ul>