Research Scientist- Molecular Biology, Cell Based Assays (Flow Cytometry, Microscopy)

Submission for the position: Research Scientist- Molecular Biology, Cell Based Assays (Flow Cytometry, Microscopy) - (Job Number: 188844)

PPD is a leading global contract research organization. At PPD we are passionate, deliberate, and driven by our purpose - to improve health.

PPD Laboratories offers the most comprehensive set of laboratory services available in the industry and continues to deliver innovative solutions to our clients through our collaborative approach, including PPD® Laboratories FSP. PPD® Laboratories FSP is a unique partnership that allows our clients to leverage the experience of our PPD staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits/advantages of being a part of PPD.

Description of Department:

The Molecular Biology group at the US Research and Development Center, GSK Vaccines, is responsible for generating and characterizing all vaccine candidates utilizing our viral vector-based vaccine technology. They provide key molecular biology and cell biology support to all GSK Vaccine projects and platforms. This group is also responsible for implementing new techniques and technology to improve high-throughput generation and screening of vaccine candidates, including high-throughput cloning and cell-based characterization.

We are looking for a highly motivated scientist, with proven record in utilizing the most up to date molecular biology and cell biology techniques in a high-throughput environment, to take a role in generating and testing new vaccine candidates

Responsibilities: To provide expertise in the areas of DNA cloning, in-vitro RNA transcription and cell-based assay characterization of vaccine candidates Utilize high-throughput workflows for molecular biology and cell biology processes to generate and characterize vaccine candidates Work with other scientists to design and develop new assays and technologies to support RNA vaccine generation and evaluation

PPD Defining Principles: 

- We have a strong will to win - We earn our customer’s trust - We are gamechangers - We do the right thing - We are one PPD - 

If you resonate with our five principles above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, then please submit your application – we’d love to hear from you.

#LI-LM2  

PPD is a leading global contract research organization. At PPD we are passionate, deliberate, and driven by our purpose - to improve health.

PPD Laboratories offers the most comprehensive set of laboratory services available in the industry and continues to deliver innovative solutions to our clients through our collaborative approach, including PPD® Laboratories FSP. PPD® Laboratories FSP is a unique partnership that allows our clients to leverage the experience of our PPD staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits/advantages of being a part of PPD.

Description of Department:

The Molecular Biology group at the US Research and Development Center, GSK Vaccines, is responsible for generating and characterizing all vaccine candidates utilizing our viral vector-based vaccine technology. They provide key molecular biology and cell biology support to all GSK Vaccine projects and platforms. This group is also responsible for implementing new techniques and technology to improve high-throughput generation and screening of vaccine candidates, including high-throughput cloning and cell-based characterization.

We are looking for a highly motivated scientist, with proven record in utilizing the most up to date molecular biology and cell biology techniques in a high-throughput environment, to take a role in generating and testing new vaccine candidates

Responsibilities: To provide expertise in the areas of DNA cloning, in-vitro RNA transcription and cell-based assay characterization of vaccine candidates Utilize high-throughput workflows for molecular biology and cell biology processes to generate and characterize vaccine candidates Work with other scientists to design and develop new assays and technologies to support RNA vaccine generation and evaluation

PPD Defining Principles: 

- We have a strong will to win - We earn our customer’s trust - We are gamechangers - We do the right thing - We are one PPD - 

If you resonate with our five principles above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, then please submit your application – we’d love to hear from you.

#LI-LM2  

Education and Experience:   Bachelor's degree or equivalent and relevant formal academic / vocational qualification Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 6 years). Or a PhD Degree and 0 years experience. In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities: Proficiency on technical operating systems At least 2 years of experience in hands-oncell culture At least 2 years experience in cell-based assays using flow cytometry and microscopy Experience in molecular biology and cloning, including gibson cloning, mutagenesis, RNA production and isolation is required Familiar with common molecular biology software e.g. Geneious Experience in RNA in vitro transcription techniques and familiarity with RNA based vaccine technology Comfortable with cell-based assays to evaluate viral vector-based vaccine candidates, for example FACS analysis or High-Content Imaging Experience operating liquid-handling robotics systems (Tecan, Hamilton) Knowledge in innate immunity Proven problem solving and troubleshooting abilities Proven ability in technical writing skills Time management and project management skills Good written and oral communication skills Ability to work in a collaborative work environment with a team

Working Environment:  

PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.  Below is listed the working environment/requirements for this role: 

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. 

Able to work upright and stationary and/or standing for typical working hours.  

Able to lift and move objects up to 25 pounds  

Able to work in non-traditional work environments.  

Able to use and learn standard office equipment and technology with proficiency.  

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. 

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. 

Education and Experience:   Bachelor's degree or equivalent and relevant formal academic / vocational qualification Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 6 years). Or a PhD Degree and 0 years experience. In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities: Proficiency on technical operating systems At least 2 years of experience in hands-oncell culture At least 2 years experience in cell-based assays using flow cytometry and microscopy Experience in molecular biology and cloning, including gibson cloning, mutagenesis, RNA production and isolation is required Familiar with common molecular biology software e.g. Geneious Experience in RNA in vitro transcription techniques and familiarity with RNA based vaccine technology Comfortable with cell-based assays to evaluate viral vector-based vaccine candidates, for example FACS analysis or High-Content Imaging Experience operating liquid-handling robotics systems (Tecan, Hamilton) Knowledge in innate immunity Proven problem solving and troubleshooting abilities Proven ability in technical writing skills Time management and project management skills Good written and oral communication skills Ability to work in a collaborative work environment with a team

Working Environment:  

PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.  Below is listed the working environment/requirements for this role: 

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. 

Able to work upright and stationary and/or standing for typical working hours.  

Able to lift and move objects up to 25 pounds  

Able to work in non-traditional work environments.  

Able to use and learn standard office equipment and technology with proficiency.  

May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. 

Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. 

Submission for the position: Research Scientist- Molecular Biology, Cell Based Assays (Flow Cytometry, Microscopy) - (Job Number: 188844)