- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00696605
Assessment of Circulating Copeptin Levels in Healthy Subjects and Patients With Renal Insufficiency After Oral Water Load and Hypertonic Saline Infusion
February 23, 2017 updated by: Jonas Rutishauser, Hospital Centre Biel/Bienne
The are 2 principal goals in this study:
- To measure plasma copeptin levels in healthy subjects and to correlate them with plasma AVP concentrations and urine osmolalities in iso-, hypo-, and hyperosmolar states.
- To measure plasma copeptin concentrations in patients with chronic renal failure under the same conditions described above, in order to characterize the impact of renal function on circulating copeptin levels in correlation to plasma AVP and urine osmolality.
Study Overview
Status
Completed
Conditions
Study Type
Observational
Enrollment (Actual)
20
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Biel/Bienne, Switzerland, 2501
- Clinic of Internal Medicine, Hospital Center
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 80 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Healthy volunteers; patients with chronic renal failure
Description
Inclusion Criteria:
- chronic renal failure grade I through IV
- healthy age-matched controls
Exclusion Criteria:
- chronic renal failure grade V
- heart failure
- liver disease
- nephrotic syndrome
- anemia (hemoglobin level < 100 g/L)
- uncontrolled hypertension (systolic BP > 160 mmHg; diastolic BP > 95 mm Hg)
- coexisting severe disease
- known thyroid disease
- known hypocortisolism
- known hypercortisolism
- known diabetes insipidus
- pregnancy
- lactation
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Other
- Time Perspectives: Prospective
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
July 1, 2008
Primary Completion (Actual)
January 1, 2009
Study Completion (Actual)
October 1, 2009
Study Registration Dates
First Submitted
June 10, 2008
First Submitted That Met QC Criteria
June 11, 2008
First Posted (Estimate)
June 12, 2008
Study Record Updates
Last Update Posted (Actual)
February 27, 2017
Last Update Submitted That Met QC Criteria
February 23, 2017
Last Verified
February 1, 2017
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- Swiss AVP-Copeptin Trial
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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