- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01686022
Grass Sensitisation and Allergic Rhinitis in Thai Patients
September 13, 2016 updated by: Punchama Pacharn, Mahidol University
The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens.
Outdoor allergen can be divided into grass, tree, or weed.
The type of grass or weed are different in various part of the world.
The allergens from grass and weed has never been studied in Thailand.
This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand.
In addition, the investigators will study about the cross-reactivity among these group of allergen.
Study Overview
Status
Completed
Intervention / Treatment
Detailed Description
To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study.
The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.
Study Type
Observational
Enrollment (Actual)
40
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Bangkok
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Bangkoknoi, Bangkok, Thailand, 10700
- Siriraj Hospital
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
10 years to 50 years (ADULT, CHILD)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Allergy Clinic
Description
Inclusion Criteria:
- Allergic rhinitis patients age 10-50 years old
- Control: healthy volunteer age 18-50 years old
Exclusion Criteria:
- Chronic illness such as cardiovascular diseases, liver diseases
- History of anaphylaxis
- Pregnancy
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Pollen Allergy
Pollen allergy and control will have the same intervention, ie.
Skin prick test and collect serum samples.Then measure the specificIgE, immunoblot, and ELISA inhibition
|
serum specific IgE binds to grass extract by immunoblot
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
October 1, 2012
Primary Completion (ACTUAL)
October 1, 2015
Study Completion (ACTUAL)
October 1, 2015
Study Registration Dates
First Submitted
September 12, 2012
First Submitted That Met QC Criteria
September 14, 2012
First Posted (ESTIMATE)
September 17, 2012
Study Record Updates
Last Update Posted (ESTIMATE)
September 14, 2016
Last Update Submitted That Met QC Criteria
September 13, 2016
Last Verified
September 1, 2016
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- NRCT_G04
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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