Effect Of Non-Surgical Periodontal Treatment On Lipoxin a4 Levels

Inclusion Criteria:

• Have at least 20 natural teeth, excluding third molars.
• Chronic periodontitis patients had at least two non-adjacent sites per quadrant with probing depth (PD) ≥ 5 mm and clinical attachment level (CAL) ≥ 5 mm with gingival inflammation, and alveolar bone loss affecting >30% of the teeth, as detected on clinical and radiographical examinations.
• Periodontally healthy control group had no sign of gingival inflammation, no PD > 3mm and no evidence of attachment or bone loss.

Exclusion Criteria:

• History of systemic disease.
• Regular use of any drugs which can effect the immune system or inflammatory response in the 6 months preceding the start of the study.
• Periodontal treatment during last 6 months that could affect periodontal status.
• Smoking.
• History of radiotherapy or chemotherapy.
• Ongoing orthodontic treatment.
• Aggressive periodontitis.
• Current pregnancy, lactation or menopause.