Search results for SEARCH[Study] TILT[Study:StudyFirstPostDate] ALL - ICH GCP - Clinical Trials Registry

ICH GCP | Clinical Trials Registry

Clinical Trials



1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 … 6462 6463 6464 6465 6466 6467 6468 6469 6470 6471 6472 6473 6474 6475 6476 6477 6478 6479 6480 6481 Last


#
NCTID/Status
Study
Last Changed
1
NCT04189952
Not yet recruiting
Acalabrutinib in Combination With R-ICE For Relapsed or Refractory Lymphoma
Conditions: Diffuse Large B Cell Lymphoma; Chronic Lymphocytic Leukemia; Small Lymphocytic Leukemia; Marginal Zone Lymphoma
Intervention: Acalabrutinib, Rituximab, Ifosfamide, Carboplatin, Etoposide
December 4, 2019
2
NCT04189939
Not yet recruiting
Computational Psychiatric Approach to Depression
Conditions: Depression
Intervention: Clinical Assessments
December 4, 2019
3
NCT04189926
Recruiting
Linking Activity, Nutrition, and Child Health
Conditions: Obesity; Child Obesity
December 4, 2019
4
NCT04189913
Withheld
[Trial of device that is not approved or cleared by the U.S. FDA]
Conditions: 
December 5, 2019
5
NCT04189900
Completed
Generation of Biological Samples Positive to Triptorelin for Anti-doping Control
Conditions: Healthy Volunteers
Intervention: Triptorelin
December 4, 2019
6
NCT04189887
Recruiting
Single Bout Exercise on Learning in PD
Conditions: Parkinson Disease
Intervention: Aerobic Exercise (cycling), Implicit Sequence Learning
December 4, 2019
7
NCT04189874
Not yet recruiting
Stool Testing With Molecular Assay to Minimize Contact Precautions
Conditions: Infectious Gastroenteritis
Intervention: Conventional Stool Testing, BioFire FilmArray Gastrointestinal Panel
December 4, 2019
8
NCT04189861
Not yet recruiting
Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction
Conditions: Postoperative Cognitive Dysfunction
Intervention: Adjustment Of General Anesthesia, EEG Monitoring
December 4, 2019
9
NCT04189848
Not yet recruiting
Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc
Conditions: Healthy Volunteers; Diabetes Mellitus, Type 2; Overweight; Obesity
Intervention: Semaglutide, Dulaglutide
December 4, 2019
10
NCT04189835
Not yet recruiting
EVITA Study - Epstein-Barr Virus Infection moniToring in renAl Transplant Recipients
Conditions: EBV Infection; EBV Viremia; Epstein-Barr Virus Associated Lymphoproliferative Disorder; Post-transplant Lymphoproliferative Disorder
Intervention: EBV DNA In Whole Blood And Plasma
December 4, 2019
11
NCT04189822
Enrolling by invitation
Hearts in Rhythm Organization (HiRO)National Registry and Bio Bank
Conditions: Sudden Cardiac Arrest; Sudden Arrhythmic Death Syndrome; Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC); Long QT Syndrome (LQTS); Hypertrophic Cardiomyopathy (HCM); Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
December 4, 2019
12
NCT04189809
Not yet recruiting
Discrepancies in Management of Hepatocellualr Carcinoma Between Practice and Recommendations
Conditions: Hepatocellular Carcinoma
December 4, 2019
13
NCT04189796
Not yet recruiting
Jarlsberg Cheese Compared to Camembert Cheese
Conditions: Healthy Women; Osteocalcin
Intervention: Cheese
December 4, 2019
14
NCT04189783
Not yet recruiting
Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)
Conditions: Retroperitoneal Sarcoma
Intervention: Liposomal Bupivacaine, Quadratus Lumborum Block, Questionnaire Administration
December 4, 2019
15
NCT04189770
Not yet recruiting
Lifestyle Behavior Influences Among African American Patients With Stage 0-III Prostate Cancer Survivors and Their Partners
Conditions: Cancer Survivor; Partner; Spouse; Stage I Prostate Cancer AJCC v8; Stage II Prostate Cancer AJCC v8; Stage IIA Prostate Cancer AJCC v8; Stage IIB Prostate Cancer AJCC v8; Stage IIC Prostate Cancer AJCC v8; Stage III Prostate Cancer AJCC v8; Stage IIIA Prostate Cancer AJCC v8; Stage IIIB Prostate Cancer AJCC v8; Stage IIIC Prostate Cancer AJCC v8
Intervention: Accelerometer, Ecological Momentary Assessment, Questionnaire Administration, Survey Administration
December 4, 2019
16
NCT04189757
Not yet recruiting
Acalabrutinib for the Treatment of Ibrutinib-Intolerant Mantle Cell Lymphoma
Conditions: Mantle Cell Lymphoma
Intervention: Acalabrutinib
December 4, 2019
17
NCT04189744
Not yet recruiting
The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract
Conditions: Pregnancy Malaria; Bacterial Vaginoses; Trichomonas Vaginitis
Intervention: IPTp-sulphadoxine-pyrimethamine Plus Metronidazole, IPTp-dihydroartemisinin-piperaquine Plus Metronidazole, IPTp-sulphadoxine-pyrimethamine
December 4, 2019
18
NCT04189731
Not yet recruiting
Non-interventional Study Evaluating the Management of Pain Using a Technique Developed and Commonly Used by the Center, in Patients Who Underwent Arthroscopic Surgery of the Shoulder in the Outpatient Setting.
Conditions: Shoulder Pain
December 4, 2019
19
NCT04189718
Completed
Comparative Evaluation of Osseodensification Versus Conventional Implant Site
Conditions: Bone Density; Implant Stability
Intervention: Osseodensification Protocol, Conventional Implant Site Preparation Protocol
December 4, 2019
20
NCT04189705
Not yet recruiting
A Study to Evaluate the Efficacy and Safety of MCT-SR in Patients With Gastritis
Conditions: Acute Gastritis; Chronic Gastritis
Intervention: MCT-SR, Mucosta Tab.
December 4, 2019
21
NCT04189692
Not yet recruiting
Evolution of Fatigue in Patients With Inflammatory Bowel Disease
Conditions: Fatigue; Inflammatory Bowel Diseases; Crohn Disease; Ulcerative Colitis
December 5, 2019
22
NCT04189679
Not yet recruiting
Identification of a Predictive Metabolic Signature of Response to Immune Checkpoint Inhibitors in Non-Small Cell Lung Carcinoma
Conditions: Non Small Cell Lung Cancer
Intervention: Immune Signature In Serum Associated To The Metabolic Signature, Meta-genomic Signature Of Intestinal Flora
December 5, 2019
23
NCT04189666
Active, not recruiting
Rivastigmine Patch Compared to Melatonin Patch in Prevention of Postoperative Delirium
Conditions: Delirium
Intervention: Rivastigmine Transdermal System [Exelon], Melatonin
December 5, 2019
24
NCT04189653
Active, not recruiting
Clinical Outcomes After Implementation of COntinuous Vital Sign Monitoring On the General Ward.
Conditions: Clinical Deterioration
Intervention: Continuous Monitoring
December 4, 2019
25
NCT04189640
Not yet recruiting
Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery
Conditions: Knee Osteoarthritis; Knee Arthropathy; Knee Pain Chronic; Knee Deformity; Knee Disease
Intervention: Postoperative Analgesia Management
December 4, 2019
26
NCT04189627
Not yet recruiting
A Study of the Effectiveness and Clinical Practice Use of Glecaprevir/Pibrentasvir in Adolescents With Chronic Hepatitis C Genotypes 1 to 6 in Russian Federation
Conditions: Hepatitis C Virus (HCV)
December 5, 2019
27
NCT04189614
Not yet recruiting
An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer
Conditions: Cancer; Non-small Cell Lung Cancer (NSCLC)
Intervention: Cofetuzumab Pelidotin
December 5, 2019
28
NCT04189601
Not yet recruiting
Complement Activation in the Lysosomal Storage Disorders
Conditions: Fabry Disease; Gaucher Disease; Niemann-Pick Disease, Type C; Lysosomal Storage Diseases
Intervention: Complement Measurements
December 4, 2019
29
NCT04189588
Not yet recruiting
A Phase 2 Exploratory Study of Intravenous QUZYTTIR™ (Cetirizine Hydrochloride Injection) Versus Intravenous Diphenhydramine in the Prevention of Hypersensitivity Infusion Reactions
Conditions: Oncology Patients Receiving Chemotherapy
Intervention: Cetirizine HCl 10 Mg/mL, Diphenhydramine 50 Mg/mL, Rituxan® (rituximab)
December 4, 2019
30
NCT04189575
Recruiting
A Text Messaging (SMS) Intervention to Improve Adherence to Stimulant Medication in Adults With ADHD in the Primary Care Setting
Conditions: Attention Deficit/Hyperactivity Disorder
Intervention: SMS Intervention
December 4, 2019
31
NCT04189562
Recruiting
A Text Messaging (SMS) Intervention to Improve Adherence to Stimulant Medications in Children With ADHD
Conditions: Attention Deficit/Hyperactivity Disorder
Intervention: SMS Intervention
December 4, 2019
32
NCT04189549
Not yet recruiting
Preclinical Detection of Sepsis Early in Hospitalized Patients Following Surgery, Injury or Severe Illness
Conditions: Sepsis
Intervention: CNA Rapid Sepsis Dx
December 4, 2019
33
NCT04189536
Active, not recruiting
An SMS Intervention to Improve Adherence to Stimulant Medications in Adults With ADHD
Conditions: Attention Deficit/Hyperactivity Disorder
Intervention: SMS Intervention
December 4, 2019
34
NCT04189523
Recruiting
Does Early Administration of Ultrasound Guided Regional Anesthesia for Long Bone Fractures Effect Long Term Patient Opioid Usage
Conditions: Bone Fracture; Opioid Use; Opioid Dependence
Intervention: SOC Pain Management, Early US Guided Nerve Block Administration
December 4, 2019
35
NCT04189510
Not yet recruiting
Use of Closed Loop Insulin Delivery for Glucose Control in Patients With Insulin Dependent Diabetes Mellitus After Kidney Transplantation
Conditions: Diabetes; Diabetes Mellitus
Intervention: Artificial Pancreas, Multiple Daily Injections
December 5, 2019
36
NCT04189497
Completed
Development of a Prognostic Tool for the Stratification of Cardiovascular Risk in Patients With Ischemic Stroke
Conditions: Stroke, Ischemic; Cardiovascular Risk Factor; Cardiovascular Diseases; Cardiovascular Morbidity
December 5, 2019
37
NCT04189484
Not yet recruiting
Pharmacodynamic Biomarkers to Support Biosimilar Development: PCSK9 Inhibitors
Conditions: Healthy Subjects; Pharmacokinetics; Pharmacodynamics
Intervention: Evolocumab, Evolocumab, Evolocumab, Evolocumab, Alirocumab, Alirocumab, Alirocumab, Alirocumab, Placebo
December 5, 2019
38
NCT04189471
Recruiting
Recovery After Cerebral Hemorrhage
Conditions: Intra Cerebral Hemorrhage; Subarachnoid Hemorrhage; Intraventricular Hemorrhage; Nontraumatic Haemorrhage
December 5, 2019
39
NCT04189458
Enrolling by invitation
Multimodal Exercise Effect on Brain Dynamics, Cognitive Functioning and Physical Fitness
Conditions: Community-dwelling Older Adults
Intervention: Multimodal Exercise Program
December 5, 2019
40
NCT04189445
Not yet recruiting
Futibatinib in Patients With Specific FGFR Aberrations
Conditions: Advanced or Metastatic Solid Tumor; Advanced or Metastatic Gastric or Gastroesophageal Cancer; Myeloid or Lymphoid Neoplasms (MPN)
Intervention: Futibatinib
December 5, 2019
41
NCT04189432
Recruiting
Efficacy and Safety of SCM-CGH in Patients With Steroid-Refractory or Dependent Chronic Graft-Versus-Host Disease
Conditions: Chronic Graft-versus-host-disease
Intervention: SCM-CGH, Placebo
December 4, 2019
42
NCT04189419
Recruiting
Safety and Efficacy of SCM-AGH in Patients With Severe Acute Pancreatitis
Conditions: Pancreatitis, Acute
Intervention: SCM-AGH, Placebo
December 4, 2019
43
NCT04189406
Not yet recruiting
Turner Syndrome Minipuberty Study
Conditions: Turner Syndrome; Infertility, Female; Premature Ovarian Failure; Gonadal Dysgenesis; Premature Menopause; Sex Chromosome Disorders; Ovarian Diseases
Intervention: Venapunction
December 4, 2019
44
NCT04189393
Not yet recruiting
Microbiome Analysis in esoPhageal, PancreatIc and Colorectal CaNcer Patients Undergoing Gastrointestinal Surgery
Conditions: Gastrointestinal Cancer; Colorectal Cancer; Pancreatic Cancer; Esophageal Cancer; Rectum Neoplasm; Esophageal Neoplasms; Pancreatic Ductal Adenocarcinoma; Colonic Neoplasms; Gastrointestinal Microbiome; Microbiota; Anastomotic Leak
December 4, 2019
45
NCT04189380
Recruiting
Therapeutic Literacy Evaluation in Liver Transplanted Patients
Conditions: Health Literacy; Liver Transplantation
Intervention: HLQ (Health Literacy Questionnaire), MoCA (Montreal Cognitive Assessment)
December 5, 2019
46
NCT04189367
Not yet recruiting
Treatment of Burning Mouth Syndrome With Integration of Traditional Chinese Medicine and Western Medicine
Conditions: Burning Mouth Syndrome
Intervention: Traditional Chinese Medicine, Clonazepam Tablets, Nutritional Supplement
December 5, 2019
47
NCT04189354
Recruiting
Study of the Synergistic Effects of Biofeedback and Transcranial Electrical Stimulation in Anxio-depressive Disorders
Conditions: Anxio-depressive Disorder
Intervention: Transcranial Direct Current Stimulation (t-DCS) Device
December 5, 2019
48
NCT04189341
Not yet recruiting
Modified-Thoracolumbar Interfascial Plane Block and Erector Spinae Plane Block Following Lumbar Spinal Surgery
Conditions: Lumbar Spine Instability; Lumbar Spinal Stenosis; Lumbar Disc Disease; Lumbar Spine Degeneration
Intervention: Erector Spinae Plane Block (Group E), Modified-thoracolumbar Interfascial Plane Block
December 5, 2019
49
NCT04189328
Completed
Comparision of Peri Implant Papilla Height Placed Micro and Macrosurgically
Conditions: Dental Implants
Intervention: Dental Implant Placement Using Magnifying Loupes And Microsurgical Instruments, Macrosurgical Dental Implant Placement
December 5, 2019
50
NCT04189315
Not yet recruiting
Relieving Burden of Hypophosphatasia in Adults With Functional Impairment Due to Chronic Disease
Conditions: Hypophosphatasia
Intervention: Asfotase Alfa
December 4, 2019

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 … 6462 6463 6464 6465 6466 6467 6468 6469 6470 6471 6472 6473 6474 6475 6476 6477 6478 6479 6480 6481 Last


Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

Alphabetic (A-Z)
By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

Alphabetic (A-Z)
By Category

Dietary
Supplements

Alphabetic (A-Z)
By Category

Sponsor/
Collaborators

Alphabetic (A-Z)
By Category

Locations

Alphabetic (A-Z)
By Category