Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Disease
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NCTID/Status
Study
Last Changed
233051
NCT00248833
Completed
Completed
Safety and Immunogenicity Study of Group B Meningococcal Vaccine to Prevent Meningitis.
Conditions: Meningitis, Meningococcal, Serogroup B
Intervention: 25ug Group B Meningococcal 44/76 MOS NOMV 5D Vaccine, 50ug Group B Meningococcal 44/76 MOS NOMV 5D Vaccine
Conditions: Meningitis, Meningococcal, Serogroup B
Intervention: 25ug Group B Meningococcal 44/76 MOS NOMV 5D Vaccine, 50ug Group B Meningococcal 44/76 MOS NOMV 5D Vaccine
January 29, 2018
233052
NCT00057434
Completed
Completed
Vitamin A Therapy for Tuberculosis
Conditions: Pulmonary Tuberculosis; HIV Infections
Intervention: Multivitamin
Conditions: Pulmonary Tuberculosis; HIV Infections
Intervention: Multivitamin
September 17, 2007
233053
NCT01178307
Active, not recruiting
Active, not recruiting
Symptom Inventory for Gastrointestinal Stromal Tumors
Conditions: Gastrointestinal Stromal Tumors
Intervention: Questionnaires, Interview, MDASI-GIST Questionnaire
Conditions: Gastrointestinal Stromal Tumors
Intervention: Questionnaires, Interview, MDASI-GIST Questionnaire
May 16, 2019
233054
NCT00129844
Completed
Completed
Study of Motexafin Gadolinium (MGd) for Second Line Treatment of Non-Small-Cell Lung Cancer
Conditions: Adenocarcinoma; Non-Small-Cell Lung Carcinoma; Lung Neoplasms
Intervention: Motexafin Gadolinium
Conditions: Adenocarcinoma; Non-Small-Cell Lung Carcinoma; Lung Neoplasms
Intervention: Motexafin Gadolinium
August 19, 2008
233055
NCT00129012
Completed
Completed
Self-Gated Breath-Hold Technique for Helical Tomotherapy in Patients With Non-Small Cell Lung Cancer
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Tomotherapy
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Tomotherapy
February 24, 2016
233056
NCT00128999
Completed
Completed
Study Using Induction Chemotherapy and Intensity-Modulated Radiation Therapy Guided by Combined CT and PET Imaging for Patients With Non-Small Cell Lung Cancer
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Intensity-Modulated Radiation Therapy
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Intensity-Modulated Radiation Therapy
February 8, 2010
233057
NCT00392769
Completed
Completed
Cetuximab in Patients With Progressive or Recurrent Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Cetuximab
Conditions: Endometrial Cancer
Intervention: Cetuximab
August 3, 2012
233058
NCT00126828
Completed
Completed
Study of Radiation Dose Intensity Concurrent With Chemotherapy For Limited Stage Small Cell Lung Cancer
Conditions: Carcinoma, Small Cell
Intervention: External Beam Radiotherapy
Conditions: Carcinoma, Small Cell
Intervention: External Beam Radiotherapy
February 23, 2016
233059
NCT00126451
Terminated
Terminated
A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED)
Conditions: Breast Cancer; Colorectal Cancer; Non-small-cell Lung Carcinoma
Intervention: MK0683, Vorinostat, Suberoylanilide Hydroxamic Acid (SAHA), Duration Of Treatment - During Each Treatment Cycle, Treatment Is Administered Twice Daily For 14 Days, Followed By 7 Days Of Rest For A Total Of 10 Cycles
Conditions: Breast Cancer; Colorectal Cancer; Non-small-cell Lung Carcinoma
Intervention: MK0683, Vorinostat, Suberoylanilide Hydroxamic Acid (SAHA), Duration Of Treatment - During Each Treatment Cycle, Treatment Is Administered Twice Daily For 14 Days, Followed By 7 Days Of Rest For A Total Of 10 Cycles
April 6, 2017
233060
NCT01172548
Completed
Completed
Safety and Efficacy Evaluation of Two Year Imatinib Treatment in Adjuvant Gastrointestinal Stromal Tumor (GIST)
Conditions: Gastrointestinal Stromal Tumors
Intervention: Imatinib Mesylate
Conditions: Gastrointestinal Stromal Tumors
Intervention: Imatinib Mesylate
May 28, 2017
233061
NCT00238420
Active, not recruiting
Active, not recruiting
Paclitaxel and Radiation Therapy With or Without Trastuzumab in Treating Patients Who Have Undergone Surgery for Bladder Cancer
Conditions: Bladder Urothelial Carcinoma; Stage I Bladder Cancer AJCC v6 and v7; Stage II Bladder Cancer AJCC v6 and v7; Stage III Bladder Cancer AJCC v6 and v7
Intervention: Paclitaxel, Radiation Therapy, Trastuzumab
Conditions: Bladder Urothelial Carcinoma; Stage I Bladder Cancer AJCC v6 and v7; Stage II Bladder Cancer AJCC v6 and v7; Stage III Bladder Cancer AJCC v6 and v7
Intervention: Paclitaxel, Radiation Therapy, Trastuzumab
November 18, 2019
233062
NCT00184834
Completed
Completed
Quality of Life and Liver Metastases
Conditions: Colorectal Liver Metastases; Quality of Life
Intervention: Quality Of Life
Conditions: Colorectal Liver Metastases; Quality of Life
Intervention: Quality Of Life
September 12, 2005
233063
NCT00462488
Completed
Completed
Study of Vicinium for Treating Patients With Non-Invasive Urothelial Carcinoma In Situ
Conditions: Urinary Bladder Cancer; Bladder Cancer; Bladder Neoplasms; Bladder Tumors
Intervention: Vicinium
Conditions: Urinary Bladder Cancer; Bladder Cancer; Bladder Neoplasms; Bladder Tumors
Intervention: Vicinium
May 12, 2015
233064
NCT03950609
Recruiting
Recruiting
Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid Tumors
Conditions: Advanced Carcinoid Tumor; Digestive System Neuroendocrine Neoplasm; Multiple Endocrine Neoplasia Type 1; Neuroendocrine Neoplasm; Unresectable Carcinoid Tumor
Intervention: Everolimus, Lenvatinib
Conditions: Advanced Carcinoid Tumor; Digestive System Neuroendocrine Neoplasm; Multiple Endocrine Neoplasia Type 1; Neuroendocrine Neoplasm; Unresectable Carcinoid Tumor
Intervention: Everolimus, Lenvatinib
October 4, 2019
233065
NCT00461851
Completed
Completed
Trial of Gemcitabine, Carboplatin, and Sorafenib in Chemotherapy-naive Patients With Advanced/Metastatic Bladder Carcinoma
Conditions: Bladder Cancer
Intervention: Gemcitabine, Carboplatin, Sorafenib
Conditions: Bladder Cancer
Intervention: Gemcitabine, Carboplatin, Sorafenib
November 15, 2017
233066
NCT00388154
Completed
Completed
Gemcitabine and Cisplatin for Advanced or Recurrent Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Gemcitabine, Cisplatin
Conditions: Endometrial Cancer
Intervention: Gemcitabine, Cisplatin
November 12, 2014
233067
NCT00122239
Unknown status
Unknown status
A Study of Gene Polymorphisms and Normal Tissue Radiation Injury in Patients Treated for Breast, Prostate, Brain, Lung, and Head and Neck Cancers
Conditions: Breast Cancer; Glioma; Prostate Cancer; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell-Lung; Head and Neck Cancer
Conditions: Breast Cancer; Glioma; Prostate Cancer; Carcinoma, Squamous Cell; Carcinoma, Non-Small-Cell-Lung; Head and Neck Cancer
March 14, 2016
233068
NCT00055965
Unknown status
Unknown status
Hospitalization Rates of Patients With Non-Small Cell Lung Cancer Treated With Gemcitabine and Either Cisplatin or Carboplatin
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Gemcitabine Hydrochloride
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Gemcitabine Hydrochloride
September 19, 2013
233069
NCT00055887
Withdrawn
Withdrawn
Chemotherapy and Radiation Therapy With or Without Efaproxiral in Treating Patients With Stage III Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Efaproxiral, Gemcitabine Hydrochloride, Paclitaxel, Vinorelbine Ditartrate, Radiation Therapy
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Efaproxiral, Gemcitabine Hydrochloride, Paclitaxel, Vinorelbine Ditartrate, Radiation Therapy
May 8, 2013
233070
NCT00055757
Completed
Completed
Tipifarnib, Gemcitabine, and Cisplatin in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Conditions: Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
Intervention: Tipifarnib, Cisplatin, Gemcitabine Hydrochloride, Laboratory Biomarker Analysis
Conditions: Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
Intervention: Tipifarnib, Cisplatin, Gemcitabine Hydrochloride, Laboratory Biomarker Analysis
June 3, 2013
233071
NCT00261378
Completed
Completed
Prospective Randomised Study of Doxorubicin in the Treatment of Hepatocellular Carcinoma by Drug-Eluting Bead Embolisation
Conditions: Primary Liver Cancer
Intervention: Transarterialchemoembolisation (TACE), DC Bead With Doxorubicin
Conditions: Primary Liver Cancer
Intervention: Transarterialchemoembolisation (TACE), DC Bead With Doxorubicin
July 8, 2019
233072
NCT00405405
Completed
Completed
Phase I of Biologics and Chemoradiation Therapy for Advanced Head and Neck Cancer
Conditions: Head and Neck Cancer; Parotid Gland Cancer; Thyroid Gland Cancer; Melanoma; Stage IV Head and Neck Cancer
Intervention: Cisplatin, Docetaxel, Bevacizumab, Erlotinib, Radiotherapy
Conditions: Head and Neck Cancer; Parotid Gland Cancer; Thyroid Gland Cancer; Melanoma; Stage IV Head and Neck Cancer
Intervention: Cisplatin, Docetaxel, Bevacizumab, Erlotinib, Radiotherapy
October 19, 2016
233073
NCT00227214
Completed
Completed
Study Evaluating Pneumococcal Meningitis in the Paediatric Population in Spain Four Years After the Marketing of Prevenar.
Conditions: Pneumococcal Meningitis
Conditions: Pneumococcal Meningitis
June 24, 2010
233074
NCT00117351
Terminated
Terminated
VELCADE in Previously Treated Patients With Stage IIIB and IV Bronchioloalveolar Carcinoma (BAC) and Adenocarcinoma With BAC Features
Conditions: Carcinoma, Non-Small-Cell Lung; Adenocarcinoma, Bronchiolo-Alveolar
Intervention: VELCADE
Conditions: Carcinoma, Non-Small-Cell Lung; Adenocarcinoma, Bronchiolo-Alveolar
Intervention: VELCADE
February 16, 2011
233075
NCT00354432
Terminated
Terminated
Soy Protein/Effexor Hormone Therapy for Prostate Cancer
Conditions: Hot Flashes; Prostate Cancer
Intervention: Oral Soy Protein/isoflavones Powder, Venlafaxine, Placebo Powder, Placebo Pill
Conditions: Hot Flashes; Prostate Cancer
Intervention: Oral Soy Protein/isoflavones Powder, Venlafaxine, Placebo Powder, Placebo Pill
November 27, 2017
233076
NCT00483327
Completed
Completed
Management of Atypical Endometrial Hyperplasia and Endometrial Carcinoma Using Megestrol Acetate
Conditions: Atypical Endometrial Hyperplasia; Endometrial Carcinoma
Intervention: Megestrol Acetate
Conditions: Atypical Endometrial Hyperplasia; Endometrial Carcinoma
Intervention: Megestrol Acetate
March 6, 2018
233077
NCT01151852
Completed
Completed
Rechallenge of Imatinib in GIST Having no Effective Treatment
Conditions: Gastrointestinal Stromal Tumors
Intervention: Imatinib, Placebo
Conditions: Gastrointestinal Stromal Tumors
Intervention: Imatinib, Placebo
June 30, 2015
233078
NCT00026663
Recruiting
Recruiting
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples From Patients With Cancer to Study Drug Resistance
Conditions: Renal Cell Carcinoma; Lung Carcinoma; Cervical Carcinoma
Conditions: Renal Cell Carcinoma; Lung Carcinoma; Cervical Carcinoma
November 23, 2019
233079
NCT00376844
Completed
Completed
External-Beam Radiation Therapy Compared With Vaginal Brachytherapy After Surgery for Stage I Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: External Beam Radiation Therapy, Vaginal Brachytherapy
Conditions: Endometrial Cancer
Intervention: External Beam Radiation Therapy, Vaginal Brachytherapy
February 26, 2018
233080
NCT04145258
Not yet recruiting
Not yet recruiting
Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous Meningitis
Conditions: Tuberculous Meningitis
Intervention: Aspirin, Placebo Of Aspirin, WHO TBM Treatment, Intensified TBM Treatment
Conditions: Tuberculous Meningitis
Intervention: Aspirin, Placebo Of Aspirin, WHO TBM Treatment, Intensified TBM Treatment
October 28, 2019
233081
NCT00375804
Terminated
Terminated
Racial Disparity in Endometrial Cancer
Conditions: Endometrial Cancer
Conditions: Endometrial Cancer
January 5, 2018
233082
NCT00054769
Completed
Completed
Diagnosing Tuberculosis in HIV Infected Children in Peru
Conditions: Tuberculosis; Tuberculosis, Pulmonary; HIV Infections
Conditions: Tuberculosis; Tuberculosis, Pulmonary; HIV Infections
September 16, 2008
233083
NCT00162578
Completed
Completed
Vancomycin Concentration in Cerebrospinal Fluid During Pneumococcal Meningitis
Conditions: Pneumococcal Meningitis
Conditions: Pneumococcal Meningitis
July 20, 2007
233084
NCT00115518
Completed
Completed
Radiation Plus Cetuximab in Locally Advanced Non-Small Cell Lung Cancer (NSCLC)
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Cetuximab
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Cetuximab
August 3, 2011
233085
NCT00373620
Unknown status
Unknown status
A Safety and Efficacy of CCRT With Paclitaxel as Adjuvant Therapy to Post-Operative Advanced Endometrial Cancer Patients
Conditions: Endometrial Cancer
Intervention: Paclitaxel
Conditions: Endometrial Cancer
Intervention: Paclitaxel
September 6, 2006
233086
NCT00054392
Withdrawn
Withdrawn
Combination Chemotherapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Gemcitabine Hydrochloride, Paclitaxel
Conditions: Lung Cancer
Intervention: Carboplatin, Gemcitabine Hydrochloride, Paclitaxel
July 10, 2013
233087
NCT00054210
Unknown status
Unknown status
Polyglutamate Paclitaxel Plus Carboplatin Compared With Paclitaxel Plus Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Paclitaxel, Paclitaxel Poliglumex
Conditions: Lung Cancer
Intervention: Carboplatin, Paclitaxel, Paclitaxel Poliglumex
July 23, 2008
233088
NCT00054197
Unknown status
Unknown status
Polyglutamate Paclitaxel Compared With Gemcitabine or Vinorelbine in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Gemcitabine Hydrochloride, Paclitaxel Poliglumex, Vinorelbine Tartrate
Conditions: Lung Cancer
Intervention: Gemcitabine Hydrochloride, Paclitaxel Poliglumex, Vinorelbine Tartrate
February 23, 2011
233089
NCT00054184
Unknown status
Unknown status
Polyglutamate Paclitaxel Compared With Docetaxel in Treating Patients With Progressive Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Docetaxel, Paclitaxel Poliglumex
Conditions: Lung Cancer
Intervention: Docetaxel, Paclitaxel Poliglumex
July 29, 2013
233090
NCT00250822
Completed
Completed
Gemcitabine and Oxaliplatin for Hepatocellular Carcinoma With Platelet Counts Greater Than 100,000 Per Microliter
Conditions: Liver Cancer
Intervention: Gemcitabine And Oxaliplatin
Conditions: Liver Cancer
Intervention: Gemcitabine And Oxaliplatin
September 23, 2011
233091
NCT00250796
Completed
Completed
Trial of Thalidomide, a- Interferon +/- Octreotide in Patients With Unresectable Hepatocellular Carcinoma
Conditions: Liver; Cancer
Intervention: Thalidomide, Alpha Interferon, Thalidomide, Interferon, Octreotide
Conditions: Liver; Cancer
Intervention: Thalidomide, Alpha Interferon, Thalidomide, Interferon, Octreotide
January 6, 2010
233092
NCT00205374
Completed
Completed
Use of Cidofovir for Recurrent Respiratory Papillomatosis
Conditions: Recurrent Respiratory Papillomatosis
Intervention: Cidofovir, Placebo
Conditions: Recurrent Respiratory Papillomatosis
Intervention: Cidofovir, Placebo
February 4, 2019
233093
NCT00145249
Completed
Completed
Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis
Conditions: Cryptococcal Meningitis
Intervention: Amphotericin B, Fluconazole
Conditions: Cryptococcal Meningitis
Intervention: Amphotericin B, Fluconazole
May 10, 2012
233094
NCT00476086
Completed
Completed
Oxaliplatin and Gemcitabine Followed by Radiation Therapy in the Management of Mixed Mullerian Tumors of the Uterus
Conditions: Mixed Mullerian Tumors of the Uterus
Intervention: Gemcitabine, Oxaliplatin, Radiation
Conditions: Mixed Mullerian Tumors of the Uterus
Intervention: Gemcitabine, Oxaliplatin, Radiation
July 26, 2018
233095
NCT00247728
Completed
Completed
PI-88 in Hepatocellular Carcinoma After Hepatectomy
Conditions: Carcinoma, Hepatocellular
Intervention: PI-88
Conditions: Carcinoma, Hepatocellular
Intervention: PI-88
October 16, 2007
233096
NCT00247676
Completed
Completed
An International Phase 2 Study Of SU011248 In Patients With Inoperable Liver Cancer
Conditions: Liver Neoplasms; Unresectable Hepatocellular Carcinoma
Intervention: Sunitinib (SU011248)
Conditions: Liver Neoplasms; Unresectable Hepatocellular Carcinoma
Intervention: Sunitinib (SU011248)
February 4, 2010
233097
NCT00168545
Completed
Completed
Immunology of Non-specific Effects of Vaccine
Conditions: Measles; Diphtheria; Tetanus; Pertussis
Intervention: Measles Vaccine
Conditions: Measles; Diphtheria; Tetanus; Pertussis
Intervention: Measles Vaccine
September 21, 2011
233098
NCT00247260
Unknown status
Unknown status
Safety of 32P BioSilicon in Patients With Hepatocellular Carcinoma
Conditions: Liver Cancer
Intervention: 32P BioSilicon
Conditions: Liver Cancer
Intervention: 32P BioSilicon
March 13, 2007
233099
NCT00053300
Completed
Completed
Thalidomide in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Thalidomide, Adjuvant Therapy
Conditions: Lung Cancer
Intervention: Thalidomide, Adjuvant Therapy
June 9, 2010
233100
NCT00052949
Completed
Completed
Imatinib Mesylate in Treating Patients With Recurrent Small Cell Lung Cancer
Conditions: Recurrent Small Cell Lung Cancer
Intervention: Imatinib Mesylate, Laboratory Biomarker Analysis
Conditions: Recurrent Small Cell Lung Cancer
Intervention: Imatinib Mesylate, Laboratory Biomarker Analysis
October 7, 2013
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.