Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Disease
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NCTID/Status
Study
Last Changed
233151
NCT00006004
Completed
Completed
Comparison of Two Combination Chemotherapy Regimens in Treating Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Gemcitabine Hydrochloride, Paclitaxel
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Gemcitabine Hydrochloride, Paclitaxel
August 16, 2013
233152
NCT00005838
Completed
Completed
Combination Chemotherapy Plus Radiation Therapy With or Without AE-941 in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed By Surgery
Conditions: Adenocarcinoma of the Lung; Adenosquamous Cell Lung Cancer; Large Cell Lung Cancer; Squamous Cell Lung Cancer; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer
Intervention: Shark Cartilage Extract AE-941, Placebo, Cisplatin, Vinorelbine Tartrate, Carboplatin, Paclitaxel, Radiation Therapy
Conditions: Adenocarcinoma of the Lung; Adenosquamous Cell Lung Cancer; Large Cell Lung Cancer; Squamous Cell Lung Cancer; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer
Intervention: Shark Cartilage Extract AE-941, Placebo, Cisplatin, Vinorelbine Tartrate, Carboplatin, Paclitaxel, Radiation Therapy
January 22, 2013
233153
NCT00005825
Unknown status
Unknown status
Combination Chemotherapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Cisplatin, Mitomycin C, Tretinoin, Vinorelbine Tartrate
Conditions: Lung Cancer
Intervention: Cisplatin, Mitomycin C, Tretinoin, Vinorelbine Tartrate
December 17, 2013
233154
NCT00005062
Completed
Completed
Radiation Therapy in Patients With Limited-Stage Small Cell Lung Cancer in Complete Remission
Conditions: Lung Cancer
Intervention: Radiation Therapy
Conditions: Lung Cancer
Intervention: Radiation Therapy
March 12, 2014
233155
NCT00004859
Terminated
Terminated
Carboplatin, Paclitaxel, and Radiation Therapy With or Without Thalidomide in Patients With Stage III Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Paclitaxel, Thalidomide, Radiation Therapy
Conditions: Lung Cancer
Intervention: Carboplatin, Paclitaxel, Thalidomide, Radiation Therapy
May 29, 2014
233156
NCT00004011
Completed
Completed
S9900: Surgery With or Without Combination Chemotherapy in Treating Patients With Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Paclitaxel, Conventional Surgery
Conditions: Lung Cancer
Intervention: Carboplatin, Paclitaxel, Conventional Surgery
January 30, 2013
233157
NCT00003869
Completed
Completed
Carboxyamidotriazole in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancer
Conditions: Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
Intervention: Carboxyamidotriazole, Placebo, Quality-of-life Assessment, Laboratory Biomarker Analysis
Conditions: Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
Intervention: Carboxyamidotriazole, Placebo, Quality-of-life Assessment, Laboratory Biomarker Analysis
May 2, 2014
233158
NCT00003803
Terminated
Terminated
Chemotherapy Plus Radiation Therapy in Treating Patients With Stage I, Stage II, or Stage III Non-small Cell Lung Cancer That Cannot Be Surgically Removed
Conditions: Lung Cancer
Intervention: Cisplatin, Gemcitabine Hydrochloride, Radiation Therapy
Conditions: Lung Cancer
Intervention: Cisplatin, Gemcitabine Hydrochloride, Radiation Therapy
July 17, 2012
233159
NCT00003566
Completed
Completed
Thoracoscopy in Patients With Stage IIIA Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Videothoracoscopy
Conditions: Lung Cancer
Intervention: Videothoracoscopy
July 12, 2016
233160
NCT00003497
Terminated
Terminated
Antineoplaston Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
Conditions: Stage IV Non-small Cell Lung Cancer
Intervention: Antineoplaston Therapy (Atengenal + Astugenal)
Conditions: Stage IV Non-small Cell Lung Cancer
Intervention: Antineoplaston Therapy (Atengenal + Astugenal)
February 1, 2018
233161
NCT00003496
Terminated
Terminated
Antineoplaston Therapy in Treating Patients With Recurrent or Extensive-Stage Small Cell Lung Cancer
Conditions: Small Cell Lung Cancer Extensive Stage
Intervention: Antineoplaston Therapy (Atengenal + Astugenal)
Conditions: Small Cell Lung Cancer Extensive Stage
Intervention: Antineoplaston Therapy (Atengenal + Astugenal)
September 26, 2017
233162
NCT00003159
Completed
Completed
Surgery With or Without Preoperative Chemotherapy in Treating Patients With Resectable Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Docetaxel, Gemcitabine Hydrochloride, Ifosfamide, Mitomycin C, Paclitaxel, Vinblastine Sulfate, Vinorelbine Tartrate, Conventional Surgery, Neoadjuvant Therapy
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Docetaxel, Gemcitabine Hydrochloride, Ifosfamide, Mitomycin C, Paclitaxel, Vinblastine Sulfate, Vinorelbine Tartrate, Conventional Surgery, Neoadjuvant Therapy
December 3, 2013
233163
NCT00003053
Unknown status
Unknown status
Combination Chemotherapy in Treating Patients With Stage I, II, or IIIA Non-small Cell Lung Cancer That Has Been Surgically Removed
Conditions: Lung Cancer
Intervention: Cisplatin, Etoposide, Adjuvant Therapy
Conditions: Lung Cancer
Intervention: Cisplatin, Etoposide, Adjuvant Therapy
September 19, 2013
233164
NCT00002852
Completed
Completed
Surgery With or Without Chemotherapy in Treating Patients With Stage I Non-small Cell Lung Cancer
Conditions: Adenocarcinoma of the Lung; Adenosquamous Cell Lung Cancer; Bronchoalveolar Cell Lung Cancer; Large Cell Lung Cancer; Squamous Cell Lung Cancer; Stage IB Non-small Cell Lung Cancer
Intervention: Paclitaxel, Carboplatin, Therapeutic Conventional Surgery
Conditions: Adenocarcinoma of the Lung; Adenosquamous Cell Lung Cancer; Bronchoalveolar Cell Lung Cancer; Large Cell Lung Cancer; Squamous Cell Lung Cancer; Stage IB Non-small Cell Lung Cancer
Intervention: Paclitaxel, Carboplatin, Therapeutic Conventional Surgery
July 2, 2013
233165
NCT00002624
Completed
Completed
Video-Assisted Surgery Followed by Radiation Therapy in Treating Patients With Stage I Non-small Cell Lung Cancer and Poor Heart and Lung Function
Conditions: Lung Cancer
Intervention: Adjuvant Therapy, Diagnostic Thoracoscopy, Therapeutic Thoracoscopy, Video-assisted Surgery, Radiation Therapy
Conditions: Lung Cancer
Intervention: Adjuvant Therapy, Diagnostic Thoracoscopy, Therapeutic Thoracoscopy, Video-assisted Surgery, Radiation Therapy
July 12, 2016
233166
NCT00002623
Completed
Completed
Chemotherapy Followed by Surgery or Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Conventional Surgery, Radiation Therapy
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Conventional Surgery, Radiation Therapy
June 29, 2012
233167
NCT00002484
Completed
Completed
Radiation Therapy Using 3-Dimensional Treatment Planning in Patients With Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Radiation Therapy
Conditions: Lung Cancer
Intervention: Radiation Therapy
October 31, 2013
233168
NCT00243841
Completed
Completed
Dose Escalation Study for Primary Hepatocellular Carcinoma
Conditions: Carcinoma, Hepatocellular
Intervention: Stereotactic Body Radiation
Conditions: Carcinoma, Hepatocellular
Intervention: Stereotactic Body Radiation
November 15, 2018
233169
NCT00051974
Completed
Completed
Phase 2 Study of VELCADE Alone or VELCADE® Plus Docetaxel in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer
Conditions: Non-Small Cell Lung Cancer
Intervention: VELCADE™ (bortezomib) For Injection (formerly PS-341)
Conditions: Non-Small Cell Lung Cancer
Intervention: VELCADE™ (bortezomib) For Injection (formerly PS-341)
February 7, 2008
233170
NCT00337155
Completed
Completed
BAY88-8223, Dose Finding Study in Patients With HRPC
Conditions: Prostate Cancer; Neoplasm Metastasis
Intervention: Radium-223 Dichloride (BAY88-8223)
Conditions: Prostate Cancer; Neoplasm Metastasis
Intervention: Radium-223 Dichloride (BAY88-8223)
December 23, 2014
233171
NCT00337077
Completed
Completed
Eribulin Mesylate in Treating Patients With Metastatic Prostate Cancer That Did Not Respond to Hormone Therapy
Conditions: Adenocarcinoma of the Prostate; Hormone-refractory Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Eribulin Mesylate
Conditions: Adenocarcinoma of the Prostate; Hormone-refractory Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Eribulin Mesylate
May 21, 2014
233172
NCT00242502
Completed
Completed
Efficacy and Safety Study of Bevacizumab and Erlotinib to Treat Primary Liver Cancer That Cannot be Removed By Surgery
Conditions: Hepatocellular Carcinoma; Liver Cancer
Intervention: Bevacizumab (Avastin), Erlotinib
Conditions: Hepatocellular Carcinoma; Liver Cancer
Intervention: Bevacizumab (Avastin), Erlotinib
March 25, 2013
233173
NCT00241020
Completed
Completed
Evaluation of the Efficacy of Long-acting Release Octreotide in Patients With Advanced Hepatocellular Carcinoma
Conditions: Advanced Hepatocellular Carcinoma
Intervention: Octreotide
Conditions: Advanced Hepatocellular Carcinoma
Intervention: Octreotide
April 11, 2016
233174
NCT00112060
Withdrawn
Withdrawn
A Study to Assess the Safety and Preliminary Efficacy of PT-523 in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)
Conditions: Non-Small-Cell Lung Carcinoma
Intervention: PT-523 For Injection
Conditions: Non-Small-Cell Lung Carcinoma
Intervention: PT-523 For Injection
March 27, 2014
233175
NCT00051493
Completed
Completed
ALIMTA Plus Carboplatin as Front-Line Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer: A Phase 2 Clinical Trial.
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: ALIMTA, Carboplatin
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: ALIMTA, Carboplatin
July 18, 2006
233176
NCT00238394
Completed
Completed
Cediranib Maleate in Treating Patients With Locally Advanced or Metastatic Liver Cancer
Conditions: Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer
Intervention: Cediranib Maleate, Laboratory Biomarker Analysis
Conditions: Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer
Intervention: Cediranib Maleate, Laboratory Biomarker Analysis
June 4, 2013
233177
NCT00299962
Active, not recruiting
Active, not recruiting
Gene Therapy for Pleural Malignancies
Conditions: Pleural Mesothelioma; Metastatic Pleural Effusions
Intervention: Adenoviral-mediated Interferon-beta, SCH 721015
Conditions: Pleural Mesothelioma; Metastatic Pleural Effusions
Intervention: Adenoviral-mediated Interferon-beta, SCH 721015
March 4, 2019
233178
NCT00234182
Completed
Completed
Postoperative Adjuvant Therapy With Recombinant Interferon-Alpha Following Curative Resection of HCC
Conditions: Hepatocellular Carcinoma
Intervention: Interferon Alpha-2b
Conditions: Hepatocellular Carcinoma
Intervention: Interferon Alpha-2b
November 29, 2005
233179
NCT00050973
Completed
Completed
Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer
Conditions: Non-small Cell Lung Cancer
Intervention: Bexarotene
Conditions: Non-small Cell Lung Cancer
Intervention: Bexarotene
May 13, 2013
233180
NCT00050960
Completed
Completed
Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer
Conditions: Non-small Cell Lung Cancer
Intervention: Bexarotene With Carboplatin And Paclitaxel, Carboplatin And Paclitaxel
Conditions: Non-small Cell Lung Cancer
Intervention: Bexarotene With Carboplatin And Paclitaxel, Carboplatin And Paclitaxel
July 7, 2012
233181
NCT00462826
Completed
Completed
VEGF Trap in Treating Patients With Recurrent or Persistent Endometrial Cancer
Conditions: Recurrent Endometrial Carcinoma
Intervention: Ziv-aflibercept
Conditions: Recurrent Endometrial Carcinoma
Intervention: Ziv-aflibercept
July 19, 2019
233182
NCT00331344
Completed
Completed
Treating Patients With Metastatic Prostate Cancer Not Responding to Hormone and Chemotherapy
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Mitoxantrone Hydrochloride, Ixabepilone, Prednisone
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Mitoxantrone Hydrochloride, Ixabepilone, Prednisone
October 2, 2017
233183
NCT00050674
Completed
Completed
Docetaxel and Gemcitabine With Filgrastim-SD/01 Support in Patients With Advanced Non-Small Cell Lung Carcinoma
Conditions: Non-small Cell Lung Cancer
Intervention: Filgrastim-SD/01
Conditions: Non-small Cell Lung Cancer
Intervention: Filgrastim-SD/01
December 26, 2012
233184
NCT00225290
Terminated
Terminated
Phase III Trial of Oral Thalidomide in Advanced Hepatocellular Carcinoma With Poor Liver Reserve
Conditions: Carcinoma, Hepatocellular
Intervention: Thalidomide(Thado)
Conditions: Carcinoma, Hepatocellular
Intervention: Thalidomide(Thado)
October 7, 2011
233185
NCT00216437
Terminated
Terminated
Dose Escalation Study Combining Oral Capecitabine (Xeloda) and Radiotherapy for Patients With Unresectable Liver or Cholangiocarcinoma
Conditions: Cancer of Liver
Intervention: Capecitabine (Xeloda)
Conditions: Cancer of Liver
Intervention: Capecitabine (Xeloda)
November 9, 2007
233186
NCT00190385
Completed
Completed
Screening of Hepatocellular Carcinoma in Patients With Compensated Cirrhosis
Conditions: Compensated Cirrhosis
Intervention: Ultrasonographic Screening
Conditions: Compensated Cirrhosis
Intervention: Ultrasonographic Screening
February 24, 2011
233187
NCT00001499
Completed
Completed
Phase II Neoadjuvant Trial of a Continuous Infusion of Paclitaxel Plus Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non-Small Cell Lung Cancer
Conditions: Carcinoma, Non-Small-Cell Lung; Lung Neoplasms
Intervention: Paclitaxel, Cisplatin, Chest Radiotherapy
Conditions: Carcinoma, Non-Small-Cell Lung; Lung Neoplasms
Intervention: Paclitaxel, Cisplatin, Chest Radiotherapy
March 3, 2008
233188
NCT00187109
Completed
Completed
Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy
Conditions: Germ Cell Tumors; Hepatic Cancer; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma
Intervention: Recombinant Human Thrombopoietin
Conditions: Germ Cell Tumors; Hepatic Cancer; Neuroblastoma; Osteosarcoma; Rhabdomyosarcoma
Intervention: Recombinant Human Thrombopoietin
April 8, 2008
233189
NCT00183885
Active, not recruiting
Active, not recruiting
A Phase II Study of Intra-arterial Chemotherapy With Cisplatin and Mitomycin-C in Patients With Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma; Liver Cancer
Intervention: Mitomycin-c, Cisplatin
Conditions: Hepatocellular Carcinoma; Liver Cancer
Intervention: Mitomycin-c, Cisplatin
May 10, 2018
233190
NCT00323882
Completed
Completed
Study of MDX-010 in Patients With Metastatic Hormone-Refractory Prostate Cancer
Conditions: Prostate Cancer; Neoplasm Metastasis
Intervention: MDX-010
Conditions: Prostate Cancer; Neoplasm Metastasis
Intervention: MDX-010
August 14, 2014
233191
NCT00178867
Completed
Completed
A National Registry of Patients With Hepatocellular Carcinoma
Conditions: Carcinoma, Hepatocellular
Conditions: Carcinoma, Hepatocellular
October 9, 2008
233192
NCT00172640
Unknown status
Unknown status
Genetic Studies in Liver Cancer Patients
Conditions: Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma
September 12, 2005
233193
NCT00168155
Completed
Completed
Study of 5-FU + Leucovorin + CPT-11 in Patients With Resectable Liver Metastases From Colorectal Adenocarcinoma
Conditions: Colorectal Adenocarcinoma; Liver Metastases
Intervention: Perioperative Chemotherapy
Conditions: Colorectal Adenocarcinoma; Liver Metastases
Intervention: Perioperative Chemotherapy
January 18, 2012
233194
NCT00050336
Terminated
Terminated
Study of Lonafarnib in Combination With Paclitaxel and Carboplatin in Patients With Non-Small Cell Lung Cancer (Study P01901)(TERMINATED)
Conditions: Carcinoma, Non-small-cell Lung; Metastases, Neoplasm
Intervention: Lonafarnib (SARASAR)
Conditions: Carcinoma, Non-small-cell Lung; Metastases, Neoplasm
Intervention: Lonafarnib (SARASAR)
August 26, 2015
233195
NCT00162669
Unknown status
Unknown status
Bevacizumab in Advanced Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma
Intervention: Bevacizumab
Conditions: Hepatocellular Carcinoma
Intervention: Bevacizumab
September 7, 2006
233196
NCT00155272
Unknown status
Unknown status
Radiotherapy Plus Thalidomide in Locally Advanced Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma
Intervention: Thalidomide
Conditions: Hepatocellular Carcinoma
Intervention: Thalidomide
September 8, 2005
233197
NCT00154817
Completed
Completed
A Phase II Study of Radiotherapy for Locally Advanced Hepatocellular Carcinoma (HCC)
Conditions: Hepatocellular Carcinoma
Intervention: Radiotherapy
Conditions: Hepatocellular Carcinoma
Intervention: Radiotherapy
November 21, 2005
233198
NCT00154544
Unknown status
Unknown status
Searching for the Liver Cancer-Related Biomarkers
Conditions: Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma
December 19, 2005
233199
NCT00321646
Completed
Completed
Neoadjuvant Bevacizumab Plus Docetaxel in High Risk Patients With Prostate Cancer Undergoing Radical Prostatectomy
Conditions: Prostate Cancer; Adenocarcinoma of the Prostate
Intervention: Bevacizumab, Docetaxel
Conditions: Prostate Cancer; Adenocarcinoma of the Prostate
Intervention: Bevacizumab, Docetaxel
April 13, 2016
233200
NCT00151671
Terminated
Terminated
Effect of a Perioperative Oral Nutritional Supplementation on Patients Undergoing Hepatic Surgery for Liver Cancer
Conditions: Liver Cancer; Hepatocellular Carcinoma; Cirrhosis; Liver Fibrosis
Intervention: Oral Impact®, Placebo
Conditions: Liver Cancer; Hepatocellular Carcinoma; Cirrhosis; Liver Fibrosis
Intervention: Oral Impact®, Placebo
February 24, 2012
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.