Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Disease
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#
NCTID/Status
Study
Last Changed
233451
NCT00016107
Completed
Completed
Combination Chemotherapy Plus Bevacizumab in Treating Patients With Metastatic Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Hormone-resistant Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Estramustine Phosphate Sodium, Docetaxel, Bevacizumab, Laboratory Biomarker Analysis
Conditions: Adenocarcinoma of the Prostate; Hormone-resistant Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Estramustine Phosphate Sodium, Docetaxel, Bevacizumab, Laboratory Biomarker Analysis
June 4, 2013
233452
NCT00035516
Completed
Completed
A Phase II Study of Epothilone Analog BMS-247550 in Patients With Non-Small Cell Lung Cancer Who Have Failed First Line Platinum Based Chemotherapy
Conditions: Carcinoma, Non-small-cell Lung
Intervention: Epothilone
Conditions: Carcinoma, Non-small-cell Lung
Intervention: Epothilone
February 9, 2016
233453
NCT00035152
Completed
Completed
Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Paclitaxel And Carboplatin
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Paclitaxel And Carboplatin
September 16, 2016
233454
NCT00034957
Completed
Completed
Study of the Efficacy of an Investigational Drug in Adult Patients With Non Small-Cell Lung Cancer (NSCLC)
Conditions: Carcinoma, Non-Small-Cell Lung; Lung Neoplasms
Conditions: Carcinoma, Non-Small-Cell Lung; Lung Neoplasms
February 14, 2012
233455
NCT00005643
Completed
Completed
Chemotherapy in Treating Patients With Sarcoma of the Uterus
Conditions: Endometrial Cancer; Sarcoma
Intervention: Pegylated Liposomal Doxorubicin Hydrochloride
Conditions: Endometrial Cancer; Sarcoma
Intervention: Pegylated Liposomal Doxorubicin Hydrochloride
June 7, 2013
233456
NCT00034164
Completed
Completed
Safety and Efficacy of S-8184 in Second Line Treatment of Relapsed Stage IIIB or IV Non Small Cell Lung Cancer
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: S-8184 Paclitaxel Injectable Emulsion
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: S-8184 Paclitaxel Injectable Emulsion
June 2, 2009
233457
NCT00471328
Completed
Completed
Efficacy and Safety of Nilotinib (AMN107) Compared With Current Treatment Options in Patients With GIST Who Have Failed Both Imatinib and Sunitinib
Conditions: Gastrointestinal Stromal Tumors
Intervention: Nilotinib, Best Supportive Care (BSC) +/- Imatinib Or Sunitinib
Conditions: Gastrointestinal Stromal Tumors
Intervention: Nilotinib, Best Supportive Care (BSC) +/- Imatinib Or Sunitinib
June 5, 2012
233458
NCT00044512
Completed
Completed
A Study to Estimate Safety and Efficacy of Sorafenib (BAY43-9006) in the Treatment of Hepatocellular Carcinoma
Conditions: Carcinoma, Hepatocellular
Conditions: Carcinoma, Hepatocellular
March 26, 2014
233459
NCT00068406
Completed
Completed
Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Cancer of the Vulva
Conditions: Stage III Vulvar Cancer; Stage IVB Vulvar Cancer; Vulvar Squamous Cell Carcinoma
Intervention: 3-Dimensional Conformal Radiation Therapy, Cisplatin, Conventional Surgery
Conditions: Stage III Vulvar Cancer; Stage IVB Vulvar Cancer; Vulvar Squamous Cell Carcinoma
Intervention: 3-Dimensional Conformal Radiation Therapy, Cisplatin, Conventional Surgery
October 17, 2017
233460
NCT00002459
Completed
Completed
Radiation Therapy or No Further Treatment Following Surgery in Treating Patients With Cancer of the Uterus
Conditions: Endometrial Cancer; Sarcoma
Intervention: Radiation Therapy
Conditions: Endometrial Cancer; Sarcoma
Intervention: Radiation Therapy
September 20, 2012
233461
NCT00043433
Unknown status
Unknown status
Study of T900607-Sodium in Chemotherapy Naive Patients With Hepatocellular Carcinoma.
Conditions: Hepatocellular Carcinoma
Intervention: Intravenous T900607-sodium
Conditions: Hepatocellular Carcinoma
Intervention: Intravenous T900607-sodium
June 23, 2005
233462
NCT00457743
Completed
Completed
A Phase I/II Study of Sunitinib Malate (SU011248) In Patients With Gastrointestinal Stromal Tumor (GIST)
Conditions: Gastrointestinal Stromal Tumors
Intervention: Sunitinib Malate (SU011248)
Conditions: Gastrointestinal Stromal Tumors
Intervention: Sunitinib Malate (SU011248)
October 2, 2009
233463
NCT00455559
Completed
Completed
Ph II Study of Perifosine Plus Gleevec for Patients With GIST
Conditions: Gastrointestinal Stromal Tumors
Intervention: Perifosine, Imatinib Mesylate
Conditions: Gastrointestinal Stromal Tumors
Intervention: Perifosine, Imatinib Mesylate
February 20, 2018
233464
NCT00058214
Terminated
Terminated
Perifosine in Treating Patients With Recurrent Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IIB Prostate Cancer; Stage III Prostate Cancer; Stage IV Prostate Cancer
Intervention: Perifosine, Laboratory Biomarker Analysis
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IIB Prostate Cancer; Stage III Prostate Cancer; Stage IV Prostate Cancer
Intervention: Perifosine, Laboratory Biomarker Analysis
February 9, 2015
233465
NCT00058084
Completed
Completed
Ixabepilone Compared With Mitoxantrone and Prednisone in Treating Patients With Refractory Metastatic Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Ixabepilone, Mitoxantrone Hydrochloride, Prednisone
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Ixabepilone, Mitoxantrone Hydrochloride, Prednisone
February 21, 2017
233466
NCT00038714
Completed
Completed
A Trial Study of SGN-00101 in Treating Pediatric Patients With Recurrent Respiratory Papillomatosis
Conditions: Papilloma; Recurrent Respiratory Papillomatosis
Intervention: SGN-00101
Conditions: Papilloma; Recurrent Respiratory Papillomatosis
Intervention: SGN-00101
June 26, 2007
233467
NCT00006377
Completed
Completed
Doxorubicin, Paclitaxel, and Carboplatin in Treating Patients With Primary Stage III, Stage IV, or Recurrent Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Carboplatin, Doxorubicin Hydrochloride, Paclitaxel
Conditions: Endometrial Cancer
Intervention: Carboplatin, Doxorubicin Hydrochloride, Paclitaxel
June 17, 2013
233468
NCT00005861
Completed
Completed
Liposomal Doxorubicin in Treating Patients With Advanced or Recurrent Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Pegylated Liposomal Doxorubicin Hydrochloride
Conditions: Endometrial Cancer
Intervention: Pegylated Liposomal Doxorubicin Hydrochloride
June 7, 2013
233469
NCT00444795
Completed
Completed
Post Marketing Surveillance Study To Observe Safety And Efficacy Of Sutene
Conditions: Gastrointestinal Stromal Tumors
Intervention: Sunitinib Malate, Sunitinib Malate, Sunitinib Malate
Conditions: Gastrointestinal Stromal Tumors
Intervention: Sunitinib Malate, Sunitinib Malate, Sunitinib Malate
December 6, 2016
233470
NCT00072137
Terminated
Terminated
Neoadjuvant Intravesical Vaccine Therapy in Treating Patients With Bladder Carcinoma Who Are Undergoing Cystectomy
Conditions: Bladder Adenocarcinoma; Bladder Squamous Cell Carcinoma; Bladder Urothelial Carcinoma; Recurrent Bladder Carcinoma; Stage I Bladder Cancer; Stage II Bladder Cancer; Stage III Bladder Cancer; Stage IV Bladder Cancer
Intervention: Recombinant Fowlpox-TRICOM Vaccine, Recombinant Fowlpox GM-CSF Vaccine Adjuvant, Therapeutic Conventional Surgery, Pharmacological Study, Laboratory Biomarker Analysis
Conditions: Bladder Adenocarcinoma; Bladder Squamous Cell Carcinoma; Bladder Urothelial Carcinoma; Recurrent Bladder Carcinoma; Stage I Bladder Cancer; Stage II Bladder Cancer; Stage III Bladder Cancer; Stage IV Bladder Cancer
Intervention: Recombinant Fowlpox-TRICOM Vaccine, Recombinant Fowlpox GM-CSF Vaccine Adjuvant, Therapeutic Conventional Surgery, Pharmacological Study, Laboratory Biomarker Analysis
December 22, 2014
233471
NCT00040755
Completed
Completed
BMS-275291 in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy
Conditions: Adenocarcinoma of the Prostate; Bone Metastases; Hormone-resistant Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Rebimastat, Laboratory Biomarker Analysis
Conditions: Adenocarcinoma of the Prostate; Bone Metastases; Hormone-resistant Prostate Cancer; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Rebimastat, Laboratory Biomarker Analysis
January 31, 2013
233472
NCT00039104
Completed
Completed
Zoledronate and BMS-275291 in Treating Patients With Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Rebimastat, Zoledronic Acid, Laboratory Biomarker Analysis
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Rebimastat, Zoledronic Acid, Laboratory Biomarker Analysis
June 4, 2013
233473
NCT00028574
Completed
Completed
Gabapentin in Treating Hot Flashes in Patients With Prostate Cancer
Conditions: Hot Flashes; Prostate Cancer
Intervention: Gabapentin, Placebo
Conditions: Hot Flashes; Prostate Cancer
Intervention: Gabapentin, Placebo
June 27, 2016
233474
NCT00005623
Completed
Completed
Cyproterone Acetate in Treating Hot Flashes Following Surgical or Chemical Castration for Prostate Cancer
Conditions: Hot Flashes; Prostate Cancer
Intervention: Cyproterone Acetate, Quality-of-life Assessment
Conditions: Hot Flashes; Prostate Cancer
Intervention: Cyproterone Acetate, Quality-of-life Assessment
March 25, 2013
233475
NCT00005067
Terminated
Terminated
Photodynamic Therapy With Lutetium Texaphyrin in Treating Patients With Locally Recurrent Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage I Prostate Cancer; Stage IIA Prostate Cancer; Stage IIB Prostate Cancer
Intervention: Motexafin Lutetium, Photodynamic Therapy
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage I Prostate Cancer; Stage IIA Prostate Cancer; Stage IIB Prostate Cancer
Intervention: Motexafin Lutetium, Photodynamic Therapy
January 15, 2013
233476
NCT00005039
Terminated
Terminated
Vaccine Therapy in Treating Patients With Advanced Adenocarcinoma of the Prostate (Prostate Cancer)
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Recombinant Fowlpox-prostate Specific Antigen Vaccine, Recombinant Vaccinia Prostate-specific Antigen Vaccine, Laboratory Biomarker Analysis
Conditions: Adenocarcinoma of the Prostate; Recurrent Prostate Cancer; Stage IV Prostate Cancer
Intervention: Recombinant Fowlpox-prostate Specific Antigen Vaccine, Recombinant Vaccinia Prostate-specific Antigen Vaccine, Laboratory Biomarker Analysis
January 23, 2013
233477
NCT00003517
Withdrawn
Withdrawn
Antineoplaston Therapy in Treating Patients With Stage III or Stage IV Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Stage III Prostate Cancer; Stage IV Prostate Cancer; Recurrent Prostate Cancer
Intervention: Antineoplaston A10, Antineoplaston AS2-1, Bicalutamide, Flutamide, Leuprolide Acetate, Alternative Product Therapy, Antiandrogen Therapy, Biological Therapy, Biologically Based Therapies, Cancer Prevention Intervention, Complementary And Alternative Therapy, Differentiation Therapy, Endocrine Therapy, Hormone Therapy
Conditions: Adenocarcinoma of the Prostate; Stage III Prostate Cancer; Stage IV Prostate Cancer; Recurrent Prostate Cancer
Intervention: Antineoplaston A10, Antineoplaston AS2-1, Bicalutamide, Flutamide, Leuprolide Acetate, Alternative Product Therapy, Antiandrogen Therapy, Biological Therapy, Biologically Based Therapies, Cancer Prevention Intervention, Complementary And Alternative Therapy, Differentiation Therapy, Endocrine Therapy, Hormone Therapy
July 9, 2013
233478
NCT00034333
Terminated
Terminated
Safety and Efficacy of Doxorubicin Adsorbed to Magnetic Beads Vs. IV Doxorubicin in Treating Liver Cancer
Conditions: Carcinoma, Hepatocellular
Intervention: MTC-DOX For Injection
Conditions: Carcinoma, Hepatocellular
Intervention: MTC-DOX For Injection
June 23, 2005
233479
NCT00072176
Completed
Completed
Temsirolimus in Treating Patients With Metastatic or Locally Advanced Recurrent Endometrial Cancer
Conditions: Endometrial Adenocarcinoma; Endometrial Adenosquamous Cell Carcinoma; Endometrial Clear Cell Carcinoma; Endometrial Papillary Serous Carcinoma; Recurrent Endometrial Carcinoma; Stage IIIA Endometrial Carcinoma; Stage IIIB Endometrial Carcinoma; Stage IIIC Endometrial Carcinoma; Stage IVA Endometrial Carcinoma; Stage IVB Endometrial Carcinoma
Intervention: Temsirolimus, Laboratory Biomarker Analysis
Conditions: Endometrial Adenocarcinoma; Endometrial Adenosquamous Cell Carcinoma; Endometrial Clear Cell Carcinoma; Endometrial Papillary Serous Carcinoma; Recurrent Endometrial Carcinoma; Stage IIIA Endometrial Carcinoma; Stage IIIB Endometrial Carcinoma; Stage IIIC Endometrial Carcinoma; Stage IVA Endometrial Carcinoma; Stage IVB Endometrial Carcinoma
Intervention: Temsirolimus, Laboratory Biomarker Analysis
February 5, 2015
233480
NCT00025467
Completed
Completed
Thalidomide in Treating Patients With Recurrent or Persistent Endometrial Cancer
Conditions: Endometrial Adenoacanthoma; Endometrial Adenocarcinoma; Endometrial Adenosquamous Cell Carcinoma; Endometrial Clear Cell Carcinoma; Endometrial Papillary Serous Carcinoma; Recurrent Endometrial Carcinoma
Intervention: Thalidomide, Laboratory Biomarker Analysis
Conditions: Endometrial Adenoacanthoma; Endometrial Adenocarcinoma; Endometrial Adenosquamous Cell Carcinoma; Endometrial Clear Cell Carcinoma; Endometrial Papillary Serous Carcinoma; Recurrent Endometrial Carcinoma
Intervention: Thalidomide, Laboratory Biomarker Analysis
January 23, 2013
233481
NCT00052312
Completed
Completed
Doxorubicin and Cisplatin With or Without Paclitaxel in Treating Patients With Locally Advanced, Metastatic, and/or Relapsed Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Cisplatin, Doxorubicin Hydrochloride, Paclitaxel
Conditions: Endometrial Cancer
Intervention: Cisplatin, Doxorubicin Hydrochloride, Paclitaxel
September 20, 2012
233482
NCT00033358
Completed
Completed
Hormone Therapy in Preventing Endometrial Cancer in Patients With a Genetic Risk For Hereditary Nonpolyposis Colon Cancer
Conditions: Endometrial Cancer
Intervention: Medroxyprogesterone, Ethinyl Estradiol, Norgestrel, Laboratory Biomarker Analysis
Conditions: Endometrial Cancer
Intervention: Medroxyprogesterone, Ethinyl Estradiol, Norgestrel, Laboratory Biomarker Analysis
May 2, 2013
233483
NCT00030485
Completed
Completed
Erlotinib in Treating Patients With Locally Advanced and/or Metastatic Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Erlotinib Hydrochloride
Conditions: Endometrial Cancer
Intervention: Erlotinib Hydrochloride
January 24, 2014
233484
NCT00023894
Completed
Completed
Flavopiridol in Treating Patients With Recurrent or Persistent Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Alvocidib
Conditions: Endometrial Cancer
Intervention: Alvocidib
June 20, 2013
233485
NCT00022620
Completed
Completed
Paclitaxel in Treating Patients With Refractory or Recurrent Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Paclitaxel
Conditions: Endometrial Cancer
Intervention: Paclitaxel
September 20, 2012
233486
NCT00006027
Completed
Completed
Comparison of Radiation Therapy With or Without Combination Chemotherapy Following Surgery in Treating Patients With Stage I or Stage II Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Cisplatin, Paclitaxel, Adjuvant Therapy, Radiation Therapy
Conditions: Endometrial Cancer
Intervention: Cisplatin, Paclitaxel, Adjuvant Therapy, Radiation Therapy
August 9, 2013
233487
NCT00005583
Completed
Completed
Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Cisplatin, Doxorubicin Hydrochloride, Epirubicin Hydrochloride, Adjuvant Therapy, Conventional Surgery, Radiation Therapy
Conditions: Endometrial Cancer
Intervention: Cisplatin, Doxorubicin Hydrochloride, Epirubicin Hydrochloride, Adjuvant Therapy, Conventional Surgery, Radiation Therapy
August 1, 2013
233488
NCT00003749
Completed
Completed
Surgery With or Without Lymphadenectomy and Radiation Therapy in Treating Patients With Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Adjuvant Therapy, Conventional Surgery, Brachytherapy, Radiation Therapy
Conditions: Endometrial Cancer
Intervention: Adjuvant Therapy, Conventional Surgery, Brachytherapy, Radiation Therapy
December 18, 2013
233489
NCT00003179
Terminated
Terminated
Surgery Plus Medroxyprogesterone in Preventing Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Medroxyprogesterone
Conditions: Endometrial Cancer
Intervention: Medroxyprogesterone
June 7, 2013
233490
NCT00002976
Terminated
Terminated
Estrogen Replacement Therapy in Treating Women With Early-Stage Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Conjugated Estrogens
Conditions: Endometrial Cancer
Intervention: Conjugated Estrogens
April 10, 2013
233491
NCT00002807
Completed
Completed
Radiation Therapy or Observation Only in Treating Patients With Endometrial Cancer Who Have Undergone Surgery
Conditions: Endometrial Cancer
Intervention: Radiation Therapy
Conditions: Endometrial Cancer
Intervention: Radiation Therapy
November 25, 2016
233492
NCT00353015
Completed
Completed
Irinotecan and Cisplatin for High Grade Neuroendocrine Carcinoma of the Gastrointestinal Tract
Conditions: Gastrointestinal Cancer; Carcinoma, Neuroendocrine
Intervention: Cisplatin, Irinotecan
Conditions: Gastrointestinal Cancer; Carcinoma, Neuroendocrine
Intervention: Cisplatin, Irinotecan
August 1, 2012
233493
NCT00385203
Completed
Completed
The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).
Conditions: Gastrointestinal Stromal Tumors; Soft Tissue Sarcomas
Intervention: AZD2171
Conditions: Gastrointestinal Stromal Tumors; Soft Tissue Sarcomas
Intervention: AZD2171
June 11, 2012
233494
NCT00012467
Completed
Completed
Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Itraconazole, Flucytosine, Fluconazole, Amphotericin B, Interferon Gamma-1b
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Itraconazole, Flucytosine, Fluconazole, Amphotericin B, Interferon Gamma-1b
May 29, 2009
233495
NCT00002306
Completed
Completed
A Study of Fluconazole in the Treatment of Cryptococcal Meningitis in Patients Who Have Not Had Success With Amphotericin B
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Fluconazole
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Fluconazole
June 23, 2005
233496
NCT00002305
Completed
Completed
A Comparison of Fluconazole and Amphotericin B in the Treatment of Cryptococcal Meningitis
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Flucytosine, Fluconazole, Amphotericin B
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Flucytosine, Fluconazole, Amphotericin B
June 23, 2005
233497
NCT00002113
Completed
Completed
A Pilot Study of Fluconazole Plus Flucytosine for the Treatment of AIDS Patients With Acute Cryptococcal Meningitis.
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Flucytosine, Fluconazole
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Flucytosine, Fluconazole
June 23, 2005
233498
NCT00002077
Completed
Completed
An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Fluconazole
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Fluconazole
June 23, 2005
233499
NCT00002076
Completed
Completed
Pilot Study of Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Fluconazole
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Fluconazole
June 23, 2005
233500
NCT00002075
Completed
Completed
Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Flucytosine, Fluconazole, Amphotericin B
Conditions: Meningitis, Cryptococcal; HIV Infections
Intervention: Flucytosine, Fluconazole, Amphotericin B
June 23, 2005
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.