Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[ConditionSearch] Disease
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NCTID/Status
Study
Last Changed
234601
NCT00008372
Completed
Completed
Chloroquinoxaline Sulfonamide in Treating Patients With Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Chloroquinoxaline Sulfonamide
Conditions: Lung Cancer
Intervention: Chloroquinoxaline Sulfonamide
October 18, 2011
234602
NCT00365391
Completed
Completed
Bevacizumab and Erlotinib in Treating Patients With Advanced Liver Cancer
Conditions: Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer; Recurrent Adult Primary Liver Cancer
Intervention: Bevacizumab, Erlotinib Hydrochloride
Conditions: Adult Primary Hepatocellular Carcinoma; Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer; Recurrent Adult Primary Liver Cancer
Intervention: Bevacizumab, Erlotinib Hydrochloride
June 10, 2015
234603
NCT00231842
Completed
Completed
Adjuvant Radiation Therapy With Ifosfamide in Patients With Mixed Mesodermal Tumors of the Uterus
Conditions: Uterine Cancer
Intervention: Ifosfamide, Radiation Therapy, Cisplatin
Conditions: Uterine Cancer
Intervention: Ifosfamide, Radiation Therapy, Cisplatin
January 3, 2019
234604
NCT00305942
Completed
Completed
Topotecan and Carboplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer
Conditions: Carcinoma, Small Cell
Intervention: Topotecan, Carboplatin
Conditions: Carcinoma, Small Cell
Intervention: Topotecan, Carboplatin
January 24, 2013
234605
NCT00072631
Completed
Completed
Erlotinib (Tarceva (Trademark), OSI-774) in Treating Patients With Advanced Non-Small Cell Lung Cancer
Conditions: Advanced Non Small Cell Lung Cancer; Failed Prior Chemotherapy
Intervention: Tarceva (Trademark) (erlotinib HCl, OSI-774)
Conditions: Advanced Non Small Cell Lung Cancer; Failed Prior Chemotherapy
Intervention: Tarceva (Trademark) (erlotinib HCl, OSI-774)
February 6, 2018
234606
NCT00802854
Completed
Completed
Post Marketing Surveillance Study To Observe Safety And Efficacy Of Eraxis® IV
Conditions: Candidemia; Other Forms of Candida Infections(Intra-abdominal Abscess, Peritonitis)
Conditions: Candidemia; Other Forms of Candida Infections(Intra-abdominal Abscess, Peritonitis)
October 26, 2018
234607
NCT00072072
Completed
Completed
Celecoxib and Erlotinib in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Celecoxib, Erlotinib Hydrochloride
Conditions: Lung Cancer
Intervention: Celecoxib, Erlotinib Hydrochloride
September 19, 2013
234608
NCT01316263
Terminated
Terminated
A Study of Olaratumab (IMC-3G3) in Previously Treated Participants With Unresectable and/or Metastatic Gastrointestinal Stromal Tumors
Conditions: Gastrointestinal Stromal Tumor (GIST)
Intervention: Olaratumab
Conditions: Gastrointestinal Stromal Tumor (GIST)
Intervention: Olaratumab
January 27, 2017
234609
NCT00459654
Completed
Completed
A Placebo-controlled Phase II Study of Bone-targeted Radium-223 in Symptomatic Hormone-refractory Prostate Cancer
Conditions: Prostate Cancer; Neoplasm Metastasis
Intervention: Radium-223 Dichloride (BAY88-8223), Saline
Conditions: Prostate Cancer; Neoplasm Metastasis
Intervention: Radium-223 Dichloride (BAY88-8223), Saline
June 24, 2014
234610
NCT00072527
Completed
Completed
Cisplatin and Irinotecan Followed by Carboplatin, Etoposide, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Etoposide, Irinotecan Hydrochloride, Radiation Therapy
Conditions: Lung Cancer
Intervention: Carboplatin, Cisplatin, Etoposide, Irinotecan Hydrochloride, Radiation Therapy
July 1, 2016
234611
NCT00459407
Completed
Completed
Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate
Conditions: Adenocarcinoma of the Prostate; Stage I Prostate Cancer; Stage II Prostate Cancer
Intervention: Defined Green Tea Catechin Extract, Placebo, Immunohistochemistry Staining Method, Immunoenzyme Technique, Laboratory Biomarker Analysis, Biopsy, Mass Spectrometry, High Performance Liquid Chromatography
Conditions: Adenocarcinoma of the Prostate; Stage I Prostate Cancer; Stage II Prostate Cancer
Intervention: Defined Green Tea Catechin Extract, Placebo, Immunohistochemistry Staining Method, Immunoenzyme Technique, Laboratory Biomarker Analysis, Biopsy, Mass Spectrometry, High Performance Liquid Chromatography
October 7, 2014
234612
NCT00004093
Terminated
Terminated
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Gemcitabine, Paclitaxel, Vinorelbine, Radiation Therapy, Navelbine, Taxol
Conditions: Lung Cancer
Intervention: Carboplatin, Gemcitabine, Paclitaxel, Vinorelbine, Radiation Therapy, Navelbine, Taxol
May 31, 2012
234613
NCT00361309
Completed
Completed
SU011248 in Advanced Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma; Liver Cancer
Intervention: SU011248
Conditions: Hepatocellular Carcinoma; Liver Cancer
Intervention: SU011248
March 16, 2014
234614
NCT00482300
Completed
Completed
Systematic Pelvic Lymphadenectomy Versus no Lymphadenectomy in Clinical Stage I-II Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Systematic Pelvic Lymphadenectomy
Conditions: Endometrial Cancer
Intervention: Systematic Pelvic Lymphadenectomy
June 4, 2007
234615
NCT00044564
Completed
Completed
Evaluation of Bay 59-8862 in Patients With Advanced Renal Cell Carcinoma
Conditions: Carcinoma, Renal Cell
Intervention: Bay 59-8862
Conditions: Carcinoma, Renal Cell
Intervention: Bay 59-8862
December 18, 2014
234616
NCT00614835
Completed
Completed
Adjuvant Docetaxel Plus Gemcitabine in Patients With Completely Resected Leiomyosarcoma (LMS) of the Uterus
Conditions: Uterine Leiomyosarcoma; Uterine Cancer
Intervention: Docetaxel Plus Gemcitabine
Conditions: Uterine Leiomyosarcoma; Uterine Cancer
Intervention: Docetaxel Plus Gemcitabine
December 21, 2015
234617
NCT00030420
Completed
Completed
Celecoxib and Docetaxel in Treating Patients With Advanced Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Celecoxib, Docetaxel
Conditions: Lung Cancer
Intervention: Celecoxib, Docetaxel
April 25, 2013
234618
NCT00357474
Completed
Completed
Comparison Study of Transarterial Chemoembolization and Percutaneous Ethanol Injection for Multiple, Small HCCs
Conditions: Hepatocellular Carcinoma
Intervention: Transarterial Chemoembolization, Percutaneous Ethanol Injection Therapy
Conditions: Hepatocellular Carcinoma
Intervention: Transarterial Chemoembolization, Percutaneous Ethanol Injection Therapy
December 2, 2013
234619
NCT00357422
Completed
Completed
Comparison Study of Operation and PEIT for Small, Solitary Hepatocellular Carcinoma (HCC)
Conditions: Hepatocellular Carcinoma
Intervention: Operation, Percutaneous Ethanol Injection Therapy
Conditions: Hepatocellular Carcinoma
Intervention: Operation, Percutaneous Ethanol Injection Therapy
September 6, 2018
234620
NCT00298896
Completed
Completed
Safety and Efficacy Clinical Study of SNS-595 in Patients With Advanced Small Cell Lung Cancer
Conditions: Carcinoma, Small Cell; Small Cell Lung Cancer
Intervention: SNS-595
Conditions: Carcinoma, Small Cell; Small Cell Lung Cancer
Intervention: SNS-595
October 19, 2017
234621
NCT00298415
Completed
Completed
Chemotherapy of Elderly Patients With Non-Small-Cell Lung Cancer (NSCLC)
Conditions: NSCLC
Intervention: Paclitaxel + Carboplatin, Monotherapy (gemcitabine Or Vinorelbine)
Conditions: NSCLC
Intervention: Paclitaxel + Carboplatin, Monotherapy (gemcitabine Or Vinorelbine)
October 24, 2013
234622
NCT00355862
Completed
Completed
Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma
Conditions: Hepatocellular Carcinoma
Intervention: CNI, MMF, Steroids, Aza Etc. (mTOR Inhibitor Free), Sirolimus
Conditions: Hepatocellular Carcinoma
Intervention: CNI, MMF, Steroids, Aza Etc. (mTOR Inhibitor Free), Sirolimus
July 29, 2014
234623
NCT00450749
Completed
Completed
Lycopene in Treating Patients Undergoing Radical Prostatectomy for Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Stage I Prostate Cancer; Stage II Prostate Cancer; Stage III Prostate Cancer
Intervention: Placebo, Therapeutic Conventional Surgery, Laboratory Biomarker Analysis, Lycopene
Conditions: Adenocarcinoma of the Prostate; Stage I Prostate Cancer; Stage II Prostate Cancer; Stage III Prostate Cancer
Intervention: Placebo, Therapeutic Conventional Surgery, Laboratory Biomarker Analysis, Lycopene
December 16, 2019
234624
NCT00450229
Completed
Completed
Diindolylmethane in Treating Patients Undergoing Surgery for Stage I or Stage II Prostate Cancer
Conditions: Adenocarcinoma of the Prostate; Prostate Cancer; Stage I Prostate Cancer; Stage II Prostate Cancer
Intervention: Diindolylmethane, Placebo, Therapeutic Conventional Surgery, Laboratory Biomarker Analysis, Pharmacological Study
Conditions: Adenocarcinoma of the Prostate; Prostate Cancer; Stage I Prostate Cancer; Stage II Prostate Cancer
Intervention: Diindolylmethane, Placebo, Therapeutic Conventional Surgery, Laboratory Biomarker Analysis, Pharmacological Study
December 3, 2015
234625
NCT00355355
Completed
Completed
A Phase 3 Study of Talaporfin Sodium and Interstitial Light Emitting Diodes Treating Hepatocellular Carcinoma (HCC)
Conditions: Carcinoma, Hepatocellular; Liver Neoplasms
Intervention: Talaporfin Sodium, Interstitial Light Emitting Diodes, Percutaneous Placement Of Device In The Liver, Standard Care
Conditions: Carcinoma, Hepatocellular; Liver Neoplasms
Intervention: Talaporfin Sodium, Interstitial Light Emitting Diodes, Percutaneous Placement Of Device In The Liver, Standard Care
January 22, 2015
234626
NCT00355238
Completed
Completed
A Phase II Open Label Study of BMS-582664 in Locally Advanced or Metastatic Hepatocellular Cancer
Conditions: Hepatocellular Carcinoma (HCC)
Intervention: Brivanib (active)
Conditions: Hepatocellular Carcinoma (HCC)
Intervention: Brivanib (active)
September 23, 2015
234627
NCT00355212
Terminated
Terminated
Comparison Between Radiofrequency Versus Ethanol Injection for the Treatment of Hepatocellular Carcinoma
Conditions: Carcinoma, Hepatocellular
Intervention: Percutaneous Ablation Of Hepatocellular Carcinoma
Conditions: Carcinoma, Hepatocellular
Intervention: Percutaneous Ablation Of Hepatocellular Carcinoma
July 21, 2006
234628
NCT00071344
Completed
Completed
Analysis of Brain Metastasis in Patients With Lung Cancer
Conditions: Carcinoma, Non-Small -Cell Lung
Conditions: Carcinoma, Non-Small -Cell Lung
March 3, 2008
234629
NCT00294762
Completed
Completed
Erlotinib (Tarceva) as a Single Agent or Intercalated With Combination Chemotherapy in Patients With EGFR Positive NSCLC
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Tarceva, Carboplatin, Paclitaxel
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Tarceva, Carboplatin, Paclitaxel
August 6, 2012
234630
NCT00070629
Completed
Completed
CPG 7909 Injection in Non-Small Cell Lung Cancer
Conditions: Carcinoma, Non-Small Cell Lung
Intervention: CPG 7909, Chemotherapy, Chemotherapy
Conditions: Carcinoma, Non-Small Cell Lung
Intervention: CPG 7909, Chemotherapy, Chemotherapy
February 9, 2009
234631
NCT00070486
Completed
Completed
Carboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Carboplatin, Celecoxib, Gemcitabine Hydrochloride, Zileuton
Conditions: Lung Cancer
Intervention: Carboplatin, Celecoxib, Gemcitabine Hydrochloride, Zileuton
June 28, 2016
234632
NCT00043407
Completed
Completed
CPG 7909 in Patients Wih Stage IV Renal Cell Cancer
Conditions: Carcinoma, Renal Cell
Intervention: CPG 7909
Conditions: Carcinoma, Renal Cell
Intervention: CPG 7909
February 11, 2009
234633
NCT00324025
Terminated
Terminated
Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS
Conditions: Cryptococcal Meningitis
Intervention: Mycograb, Placebo
Conditions: Cryptococcal Meningitis
Intervention: Mycograb, Placebo
December 11, 2008
234634
NCT01294202
Completed
Completed
A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GIST
Conditions: Gastrointestinal Stromal Tumor (GIST)
Intervention: AT13387 And Imatinib
Conditions: Gastrointestinal Stromal Tumor (GIST)
Intervention: AT13387 And Imatinib
January 8, 2016
234635
NCT00351195
Terminated
Terminated
Etoposide, Oxaliplatin and Capecitabine in Advanced Hepatocellular Carcinoma (HCC)
Conditions: Hepatocellular Carcinoma
Intervention: Etoposide, Oxaliplatin, Capecitabine
Conditions: Hepatocellular Carcinoma
Intervention: Etoposide, Oxaliplatin, Capecitabine
August 25, 2008
234636
NCT00598845
Unknown status
Unknown status
Molecular Markers in Treatment in Endometrial Cancer
Conditions: Endometrial Neoplasms; Neoplasm Metastasis
Intervention: Tumor Biopsy Study
Conditions: Endometrial Neoplasms; Neoplasm Metastasis
Intervention: Tumor Biopsy Study
December 22, 2014
234637
NCT00005630
Completed
Completed
Vaccine Therapy and Sargramostim in Treating Patients With Non-small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Ras Peptide Cancer Vaccine, Sargramostim
Conditions: Lung Cancer
Intervention: Ras Peptide Cancer Vaccine, Sargramostim
June 18, 2013
234638
NCT00290550
Terminated
Terminated
A Phase IIA Study of MK0457 in Patients With Cancer of the Lung (0457-006)
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: MK0457
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: MK0457
July 24, 2015
234639
NCT00470067
Terminated
Terminated
Doxorubicin Hydrochloride Liposome and Carboplatin in Treating Patients With Recurrent, Stage III, or Stage IV Primary Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Carboplatin, Pegylated Liposomal Doxorubicin Hydrochloride
Conditions: Endometrial Cancer
Intervention: Carboplatin, Pegylated Liposomal Doxorubicin Hydrochloride
August 8, 2014
234640
NCT00444730
Completed
Completed
Urology Database for Outcomes Research
Conditions: Prostate Cancer; Pelvic Pain; Incontinence
Intervention: Radical Prostatectomy, InterStim Implantation, Pelvic Organ Prolapse Repair
Conditions: Prostate Cancer; Pelvic Pain; Incontinence
Intervention: Radical Prostatectomy, InterStim Implantation, Pelvic Organ Prolapse Repair
August 26, 2014
234641
NCT00004883
Completed
Completed
Trastuzumab in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer That Overexpresses HER2
Conditions: Recurrent Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
Intervention: Trastuzumab, Laboratory Biomarker Analysis
Conditions: Recurrent Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
Intervention: Trastuzumab, Laboratory Biomarker Analysis
January 15, 2013
234642
NCT01289028
Completed
Completed
Efficacy of Nilotinib in Adult Patients With Gastrointestinal Stromal Tumors Resistant to Imatinib and Sunitinib.
Conditions: Gastrointestinal Stromal Tumors
Intervention: Nilotinib
Conditions: Gastrointestinal Stromal Tumors
Intervention: Nilotinib
November 15, 2016
234643
NCT00595725
Completed
Completed
Intra-Operative Lymphatic Mapping in Patients With Invasive Carcinoma of the Cervix or Endometrial Carcinoma
Conditions: Cervical Cancer; Endometrial Cancer; Cervical Carcinoma
Intervention: Lymphatic Mapping
Conditions: Cervical Cancer; Endometrial Cancer; Cervical Carcinoma
Intervention: Lymphatic Mapping
September 7, 2011
234644
NCT03486678
Recruiting
Recruiting
SHR-1210 in Combination With GEMOX in Patients With Advanced BTC
Conditions: Biliary Tract Cancer; Cholangiocarcinoma
Intervention: SHR-1210+GEMOX
Conditions: Biliary Tract Cancer; Cholangiocarcinoma
Intervention: SHR-1210+GEMOX
May 9, 2018
234645
NCT00003281
Completed
Completed
Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer
Conditions: Lung Cancer
Intervention: Paclitaxel, Topotecan Hydrochloride, Radiation Therapy
Conditions: Lung Cancer
Intervention: Paclitaxel, Topotecan Hydrochloride, Radiation Therapy
July 12, 2016
234646
NCT00451880
Completed
Completed
Study of XL281 in Adults With Solid Tumors
Conditions: Cancer; Non-small-cell Lung Cancer; Colorectal Cancer; Papillary Thyroid Cancer; Melanoma
Intervention: XL281, Famotidine
Conditions: Cancer; Non-small-cell Lung Cancer; Colorectal Cancer; Papillary Thyroid Cancer; Melanoma
Intervention: XL281, Famotidine
October 11, 2011
234647
NCT00283634
Terminated
Terminated
A Study of Tarceva for Use in Patients With Relapsed or Refractory Metastatic Non-Small Cell Lung Cancer
Conditions: NSCLC
Intervention: Erlotinib And Bortezomib
Conditions: NSCLC
Intervention: Erlotinib And Bortezomib
February 16, 2011
234648
NCT00438464
Completed
Completed
Finasteride in Treating Patients With Stage II Prostate Cancer Who Are Undergoing Surgery
Conditions: Adenocarcinoma of the Prostate; Stage II Prostate Cancer
Intervention: Finasteride, Placebo, Prostatectomy, Laboratory Biomarker Analysis
Conditions: Adenocarcinoma of the Prostate; Stage II Prostate Cancer
Intervention: Finasteride, Placebo, Prostatectomy, Laboratory Biomarker Analysis
February 10, 2016
234649
NCT00462969
Completed
Completed
Cytologic Analysis of Distention Media as a Screening Test for Endometrial Cancer
Conditions: Endometrial Cancer
Intervention: Sonohysterography
Conditions: Endometrial Cancer
Intervention: Sonohysterography
November 15, 2019
234650
NCT00068289
Completed
Completed
Bortezomib in Treating Patients With Recurrent or Refractory Extensive-Stage Small Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy
Conditions: Lung Cancer
Intervention: Bortezomib
Conditions: Lung Cancer
Intervention: Bortezomib
June 21, 2013
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
Countries and States
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state.
Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.