ICH GCP | Clinical Trials Registry

Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ALL



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NCTID/Status
Study
Last Changed
310551
NCT00002388
Completed
A Study of 1592U89 in HIV-Infected Patients
Conditions: HIV Infections
Intervention: Abacavir Sulfate
June 23, 2005
310552
NCT00002387
Completed
The Safety and Effectiveness of Indinavir Sulfate Plus Efavirenz
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Efavirenz
June 23, 2005
310553
NCT00002386
Completed
Effect of Indinavir Plus Two Other Anti-HIV Drugs on Blood Clotting in HIV-Positive Males With Hemophilia
Conditions: HIV Infections; Hemophilia A
Intervention: Indinavir Sulfate, Lamivudine, Stavudine, Zidovudine, Zalcitabine, Didanosine
June 23, 2005
310554
NCT00002385
Completed
The Safety and Effectiveness of Fozivudine Tidoxil in HIV-1 Infected Patients
Conditions: HIV Infections
Intervention: Fozivudine Tidoxil
June 23, 2005
310555
NCT00002384
Unknown status
A Study of Cidofovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS
Conditions: Cytomegalovirus Retinitis; HIV Infections
Intervention: Cidofovir
June 23, 2005
310556
NCT00002383
Completed
A Comparison of Saquinavir Hard- and Soft-Gelatin Capsules in HIV-Infected Patients
Conditions: HIV Infections
Intervention: Saquinavir
June 23, 2005
310557
NCT00002382
Completed
A Study of Saquinavir Used Alone or in Combination With Other Anti-HIV Drugs in HIV-Infected Patients
Conditions: HIV Infections
Intervention: Saquinavir
June 23, 2005
310558
NCT00002381
Completed
The Safety and Effectiveness of Nevirapine Plus Nelfinavir in HIV-1 Infected Patients Who Have Taken Stavudine
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate, Nevirapine, Stavudine
June 23, 2005
310559
NCT00002380
Completed
The Safety and Effectiveness of Two Forms of Saquinavir Combined With Other Anti-HIV Drugs in HIV-Infected Infants and Children
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate, Saquinavir
June 23, 2005
310560
NCT00002379
Completed
The Safety and Effectiveness of Adefovir Dipivoxil Plus Indinavir Combined With Zidovudine or Lamivudine or Stavudine in HIV-Infected Patients Who Have Not Taken Anti-HIV Drugs
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Levocarnitine, Adefovir Dipivoxil, Lamivudine, Stavudine, Zidovudine
June 23, 2005
310561
NCT00002378
Completed
A Comparison of Three Anti-HIV Drug Combinations Containing Saquinavir Soft Gelatin Capsules Used in HIV-1 Infected Patients
Conditions: HIV Infections
Intervention: Ritonavir, Nelfinavir Mesylate, Saquinavir, Delavirdine Mesylate, Lamivudine, Stavudine, Zidovudine
June 23, 2005
310562
NCT00002377
Completed
A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes
Conditions: Cytomegalovirus Retinitis; HIV Infections
Intervention: Valganciclovir, Ganciclovir
May 15, 2017
310563
NCT00002376
Completed
The Effectiveness of HIV RNA Viral Load Testing in Determining Treatment Type in HIV-Infected Patients
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Lamivudine, Stavudine, Zidovudine, Didanosine
June 23, 2005
310564
NCT00002375
Completed
Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected Patients
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Nelfinavir Mesylate
June 23, 2005
310565
NCT00002374
Completed
A Study of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs in HIV-1 Infected Patients
Conditions: HIV Infections
Intervention: Ritonavir, Nelfinavir Mesylate, Saquinavir, Stavudine
June 23, 2005
310566
NCT00002373
Completed
The Safety and Effectiveness of Different Dose Levels of 1263W94 in the Treatment of Cytomegalovirus (CMV) of the Eyes in HIV-Infected Patients
Conditions: Cytomegalovirus Infections; HIV Infections
Intervention: Maribavir
June 23, 2005
310567
NCT00002372
Completed
A Study of 141W94 in Combination With Other Anti-HIV Drugs
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Amprenavir, Nelfinavir Mesylate, Saquinavir
June 23, 2005
310568
NCT00002371
Completed
The Safety and Effectiveness of Lamivudine Plus Stavudine or Zidovudine in HIV-Infected Patients Who Have Taken Zidovudine
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Lamivudine, Stavudine, Zidovudine
April 28, 2011
310569
NCT00002370
Completed
Study of Itraconazole in Patients With Advanced HIV Infection
Conditions: HIV Infections
Intervention: Itraconazole
June 23, 2005
310570
NCT00002369
Completed
A Comparison of Epivir Plus Crixivan Combined With Zerit or Retrovir in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Lamivudine, Stavudine, Zidovudine
October 1, 2007
310571
NCT00002368
Completed
The Safety and Effectiveness of Nevirapine Plus Lamivudine Plus Other Anti-HIV Drugs
Conditions: HIV Infections
Intervention: Nevirapine, Lamivudine
June 23, 2005
310572
NCT00002367
Completed
A Study of Saquinavir Soft Gelatin Capsules Plus Zidovudine Plus Lamivudine in the Treatment of HIV-1 Infected Patients Who Have Never Taken Anti-HIV Drugs
Conditions: HIV Infections
Intervention: Saquinavir, Lamivudine, Zidovudine
June 23, 2005
310573
NCT00002366
Completed
The Safety and Effectiveness of Ritonavir in the Treatment of HIV-Related Kaposi's Sarcoma
Conditions: Sarcoma, Kaposi; HIV Infections
Intervention: Ritonavir
February 19, 2009
310574
NCT00002365
Completed
A Study of LXR015-1 in HIV-Infected Patients
Conditions: HIV Infections
Intervention: LXR015-1
June 23, 2005
310575
NCT00002364
Completed
A Study of 1592U89 Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs
Conditions: HIV Infections
Intervention: Abacavir Sulfate
June 23, 2005
310576
NCT00002363
Completed
The Safety and Effectiveness of SPC3 in HIV-1 Infected Patients
Conditions: HIV Infections
Intervention: Peptide Construction 3, Synthetic
June 23, 2005
310577
NCT00002362
Suspended
A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
Conditions: HIV Infections
Intervention: Abacavir Sulfate, Efavirenz, Emtricitabine, Stavudine
June 23, 2005
310578
NCT00002361
Completed
Safety and Effectiveness of an Anti-HIV Drug Combination in HIV-Positive Patients Who Have Failed Previous Treatment With Protease Inhibitors
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Ritonavir
June 23, 2005
310579
NCT00002360
Completed
A Study Comparing Two Forms of Didanosine in HIV-infected Patients
Conditions: HIV Infections
Intervention: Didanosine
April 13, 2011
310580
NCT00002359
Completed
A Multicenter, Double-Blind, Phase III, Adjuvant-Controlled Study of the Effect of 10 Units of HIV-1 Immunogen (Remune) Compared to Incomplete Freund's Adjuvant (IFA) Alone Every 12 Weeks on AIDS-Free Survival in Subjects With HIV Infection and CD4 T-Lymphocytes Between 300 and 549 Cells/microL Rega
Conditions: HIV Infections
Intervention: HIV-1 Immunogen
June 23, 2005
310581
NCT00002358
Completed
A Study of BV-araU in the Treatment of Varicella-Zoster Viral Disease (VZV) in HIV-Infected Children Who Have Not Had Success With or Who Cannot Take Other Treatments for VZV
Conditions: HIV Infections; Chickenpox
Intervention: Sorivudine
October 1, 2007
310582
NCT00002357
Completed
The Safety and Effectiveness of HBY 097 Used With or Without AZT in HIV-Infected Patients Who Have Mild or No Symptoms
Conditions: HIV Infections
Intervention: HBY 097, Zidovudine
June 23, 2005
310583
NCT00002356
Completed
The Safety and Effectiveness of ISIS 2922 in Patients With AIDS Who Have Cytomegalovirus (CMV) of the Eyes
Conditions: Cytomegalovirus Retinitis; HIV Infections
Intervention: Fomivirsen Sodium
June 23, 2005
310584
NCT00002355
Completed
A Comparison of ISIS 2922 Used Immediately or Later in Patients With Cytomegalovirus (CMV) of the Eyes
Conditions: Cytomegalovirus Retinitis; HIV Infections
Intervention: Fomivirsen Sodium
June 23, 2005
310585
NCT00002354
Completed
A Study of Indinavir Sulfate Given Together With Stavudine to HIV-Positive Patients
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Stavudine
June 23, 2005
310586
NCT00002353
Completed
A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Immunotherapeutic P3C541b in HIV-1 Seropositive Human Subjects
Conditions: HIV Infections
Intervention: P3C541b Lipopeptide
June 23, 2005
310587
NCT00002352
Completed
A Study of Lobucavir in Patients With AIDS
Conditions: Cytomegalovirus Infections; HIV Infections
Intervention: Lobucavir
October 1, 2007
310588
NCT00002351
Completed
A Study of L-735,524 in HIV-Positive Children and Adolescents
Conditions: HIV Infections
Intervention: Indinavir Sulfate
June 23, 2005
310589
NCT00002350
Completed
A Phase I Trial of APL 400-003 Vaccine: Safety and Immune Response Evaluations of Multiple Injections at Escalating Doses in Asymptomatic HIV-Infected Patients
Conditions: HIV Infections
Intervention: APL 400-003
June 23, 2005
310590
NCT00002349
Completed
A Pilot Study to Compare the Antiviral and Immunologic Effects of Stavudine ( d4T ) Versus Placebo in Subjects With Evidence of Recent HIV Infection.
Conditions: HIV Infections
Intervention: Stavudine
April 13, 2011
310591
NCT00002348
Completed
A Study of Mitoguazone Dihydrochloride in Patients With AIDS-Related Non-Hodgkin's Lymphoma
Conditions: Lymphoma, Non-Hodgkin; HIV Infections
Intervention: Mitoguazone
August 1, 2018
310592
NCT00002347
Completed
The Safety and Effectiveness of Retrovir Plus HIVID Combined With Either Nevirapine or Invirase in the Treatment of HIV Infection
Conditions: HIV Infections
Intervention: Saquinavir, Nevirapine, Zidovudine, Zalcitabine
June 23, 2005
310593
NCT00002346
Completed
The Safety and Effectiveness of Bis-POM PMEA in HIV-Infected Patients
Conditions: HIV Infections
Intervention: Adefovir Dipivoxil
June 23, 2005
310594
NCT00002345
Completed
The Safety and Effectiveness of Megace in HIV-Infected Women
Conditions: Anorexia; Cachexia; HIV Infections
Intervention: Megestrol Acetate
October 1, 2007
310595
NCT00002344
Completed
A Study of Azithromycin in HIV-Infected Patients
Conditions: Bacterial Infections; HIV Infections
Intervention: Azithromycin
June 23, 2005
310596
NCT00002343
Completed
A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS
Conditions: Mycobacterium Avium-Intracellulare Infection; HIV Infections
Intervention: Ethambutol Hydrochloride, Rifabutin
June 23, 2005
310597
NCT00002342
Completed
A Study of Tecogalan Sodium
Conditions: Sarcoma, Kaposi; HIV Infections
Intervention: Tecogalan Sodium
June 23, 2005
310598
NCT00002341
Completed
A Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With Fluconazole
Conditions: Candidiasis, Oral; HIV Infections
Intervention: Itraconazole
June 23, 2005
310599
NCT00002340
Completed
A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX
Conditions: Pneumonia, Pneumocystis Carinii; HIV Infections
Intervention: Atovaquone, Pentamidine Isethionate
June 23, 2005
310600
NCT00002339
Completed
A Study of Fluconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems
Conditions: Candidiasis, Esophageal; HIV Infections
Intervention: Fluconazole
June 23, 2005

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Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

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By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

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By Category

Dietary
Supplements

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By Category

Sponsor/
Collaborators

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Locations

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By Category