Director, Immunology

Director, Immunology Req ID #:  112131 Location: 

South San Francisco, CA, US, 94080 For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary We are seeking an experienced Director, Immunologyfor our growingDiscoverysite located inSouth San Francisco, CA.

At Distributed Bio, a Charles River Laboratory company, our mission is to define a new paradigm in revolutionary bioengineered medicines for the biotechnology industry. In monoclonal therapeutics, our integration of computational immunology, bioengineering and robotics has enabled us to create a pipeline of molecules with unprecedented biophysical properties, while also supporting all of our partners with developable antibodies against any drug target of interest.

Our ability to discover antibodies against challenging pMHC, pathogen toxin, GPCR and Ion Channel targets, as well as a novel high-throughput discovery of CAR-T, has resulted in the growth of our antibody discovery business.

We are seeking a candidate with relevant experience who possesses a broad knowledge in the fields of immunology, molecular immunology and antibody discovery. This position will lead a team driving the experimental design and execution of research in antibody discovery, cell biology, immunology, and assay development. Major responsibilities will include working with internalteams and external partners to define and interrogate relevant biology and antibody mechanism of action, to enable lead candidate selection with the goalof developing novel therapeutic approaches.

The following are minimum requirements related to theDirector, Immunologyposition:

Education: Ph.D. in Immunology, biochemistry and/or molecular biologyor related discipline preferred. Track record of publications and innovation. Experience: 10 years of laboratory experience in the contract research industry or pharmaceutical environment. At least 2 years management experience. An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above. Strong skills in cellular and molecular immunology, cancer immunology, and flow cytometry techniques. Expertise in generating and maintaining cell lines and primary immune cell cultures and antibody-related assays. Demonstrated ability to design and supervise all aspects of in vitro and in vivo cancer immunotherapy models. Demonstrated ability to lead a team and supervise experienced scientists. Other: Ability to design and deliver novel solutions to challening problems. Ability to critically evaluate written scientific documents for overall quality, clarity of presentation, and acceptability of scientific interpretation. Ability to handle multiple projects, prioritize work and meet deadlines in fast paced collaborative team environment. Excellent verbal and written communication skills. Demonstrated independent analytical and problem-solving abilities. Demonstrated proficiency in managing a laboratory area. Demonstrated knowledge and full understanding of regulatory requirements, site Standard Operating Procedures (SOPs), company practices, and industry standards. Computer proficiency in MS Word, Excel, Outlook.

About Discovery

Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 13,000 employees within 80 facilities in 23 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 80% of the drugs approved by the FDA in 2017.

For more information, please visit www.criver.com.

Equal Employment Opportunity

Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet

Nearest Major Market: San Francisco

Nearest Secondary Market: Oakland

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