EudraCT Number: 2019-004676-18 Sponsor Protocol Number: 213340 Start Date: 2022-07-07
Sponsor Name: University Medical Center Utrecht
Full Title: Differences in effect of treatment with mepolizumab and benralizumab on resident and inflammatory eosinophils
Medical condition: severe eosinophilic asthma
Disease: Version SOC Term Classification Code Term Level
20.0 10038738 - Respiratory, thoracic and mediastinal disorders 10003553 Asthma PT
Population Age: Adults Gender: Male, Female
Trial protocol: NL (Ongoing)
Trial results: (No results available)

EudraCT Number: 2021-000857-23 Sponsor Protocol Number: D7020C00001 Start Date: 2022-07-06
Sponsor Name: AstraZeneca AB
Full Title: A Phase I/II, Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD2936 Anti TIGIT/Anti-PD-1 Bispecific Antibody in Pa...
Medical condition: Advanced Non-small Cell Lung Cancer, Metastatic Non-small Cell Lung Cancer, stage III unresectable Non-small Cell Lung Cancer, stage IV Non-small Cell Lung Cancer.
Disease: Version SOC Term Classification Code Term Level
20.1 100000004864 10080083 Advanced lung cancer LLT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: DK (Ongoing) BE (Ongoing) NL (Ongoing) ES (Ongoing)
Trial results: (No results available)
EudraCT Number: 2021-005319-30 Sponsor Protocol Number: 217917 Start Date: 2022-07-05
Sponsor Name: GlaxoSmithKline Biologicals
Full Title: A phase 3b, open-label, multi-country, multi-centre, long-term follow-up study of ZOSTER-049 (follow-up of ZOSTER-006/022 studies) to assess the prophylactic efficacy, safety and persistence of imm...
Medical condition: Vaccination against HZ and its related complications in adults older than 50 years (at the time of primary vaccination).
Disease: Version SOC Term Classification Code Term Level
20.0 10021881 - Infections and infestations 10019974 Herpes zoster PT
21.1 10029205 - Nervous system disorders 10036376 Post herpetic neuralgia PT
20.1 10021881 - Infections and infestations 10030865 Ophthalmic herpes zoster PT
20.0 10021881 - Infections and infestations 10063491 Herpes zoster oticus PT
21.1 10021881 - Infections and infestations 10075611 Varicella zoster virus infection PT
20.0 10021881 - Infections and infestations 10074297 Herpes zoster cutaneous disseminated PT
23.1 10021881 - Infections and infestations 10080516 Herpes zoster reactivation PT
23.1 10021881 - Infections and infestations 10084396 Disseminated varicella zoster virus infection PT
20.0 10021881 - Infections and infestations 10072210 Genital herpes zoster PT
20.1 10021881 - Infections and infestations 10061208 Herpes zoster infection neurological PT
20.0 10021881 - Infections and infestations 10074259 Herpes zoster meningitis PT
20.0 10021881 - Infections and infestations 10074248 Herpes zoster meningoencephalitis PT
20.0 10021881 - Infections and infestations 10074243 Varicella zoster oesophagitis PT
21.1 10021881 - Infections and infestations 10074254 Varicella zoster pneumonia PT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: FI (Ongoing)
Trial results: (No results available)

EudraCT Number: 2022-002190-28 Sponsor Protocol Number: SHP674-201\CL1-95014-001 Start Date: 2022-07-04
Sponsor Name: Institut de Recherches Internationales Servier (IRIS)
Full Title: A Phase 2 Clinical Study of SHP674 in Patients with Newly Diagnosed, Untreated Acute Lymphoblastic Leukemia
Medical condition: Acute Lymphoblastic Leukemia
Disease: Version SOC Term Classification Code Term Level
21.0 100000004864 10000845 Acute lymphoblastic leukemia LLT
Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
Trial protocol: Outside EU/EEA
Trial results: (No results available)
EudraCT Number: 2021-000270-28 Sponsor Protocol Number: NL75171.058.20 Start Date: 2022-06-30
Sponsor Name: Leiden University Medical Center
Full Title: Selective Indocyanine Green Injection of a Segmental Hepatic Artery Followed by Near-Infrared Fluorescence Guided Anatomical Liver Resection: A Feasibility Study
Medical condition: Hepatocellular carcinoma, hepatic adenoma, intrahepatic cholangiocarcinoma, colorectal liver metastases
Disease: Version SOC Term Classification Code Term Level
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: NL (Ongoing)
Trial results: (No results available)

EudraCT Number: 2021-005344-30 Sponsor Protocol Number: TETRA-pilot Start Date: 2022-06-29
Sponsor Name: Amsterdam UMC, location VUmc
Full Title: TETRA-pilot: Testosterone in transgender women after vaginoplasty: a dose-finding and feasibility pilot study
Medical condition: Low testosterone levels in transgender women who underwent a vaginoplasty. We will investigate the serum testosterone levels at different doses of testosteron gel and if there are side effects.
Disease: Version SOC Term Classification Code Term Level
Population Age: Adults Gender: Female
Trial protocol: NL (Ongoing)
Trial results: (No results available)
EudraCT Number: 2022-001283-10 Sponsor Protocol Number: NL80929.091.22 Start Date: 2022-06-28
Sponsor Name: Radboud University Medical Center
Full Title: The effects of medication induced blood pressure reduction on cerebral hemodynamics in hypertensive frail elderly
Medical condition: Hypertension
Disease: Version SOC Term Classification Code Term Level
Population Age: Elderly Gender: Male, Female
Trial protocol: NL (Ongoing)
Trial results: (No results available)

EudraCT Number: 2021-006611-29 Sponsor Protocol Number: 80009 Start Date: 2022-06-28
Sponsor Name: University Medical Centre Utrecht Department of Vascular Surgery
Full Title: A randomized placebo-controlled double-blind trial studying the effect of antiplatelet monotherapy (clopidogrel) versus dual antiplatelet therapy (clopidogrel + aspirin) on the occurrence of athero...
Medical condition: (Chronic) Peripheral (occlusive) arterial disease (PAD)
Disease: Version SOC Term Classification Code Term Level
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: NL (Ongoing)
Trial results: (No results available)
EudraCT Number: 2021-003715-26 Sponsor Protocol Number: C4221022 Start Date: 2022-06-27
Sponsor Name: Pfizer Inc.
Full Title: A PHASE 2, RANDOMIZED, OPEN-LABEL STUDY OF ENCORAFENIB AND CETUXIMAB PLUS PEMBROLIZUMAB VERSUS PEMBROLIZUMAB ALONE IN PARTICIPANTS WITH PREVIOUSLY UNTREATED BRAF V600E-MUTANT, MSI-H/DMMR METASTATIC...
Medical condition: MSI-H/dMMR metastatic colorectal cancer.
Disease: Version SOC Term Classification Code Term Level
21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10061451 Colorectal cancer PT
21.0 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps) 10052358 Colorectal cancer metastatic PT
Population Age: Adolescents, Under 18, Adults, Elderly Gender: Male, Female
Trial protocol: NO (Ongoing) DE (Ongoing) ES (Ongoing) SE (Ongoing) BE (Ongoing) SK (Ongoing) DK (Ongoing) NL (Ongoing) PL (Ongoing) CZ (Ongoing)
Trial results: (No results available)

EudraCT Number: 2021-002968-49 Sponsor Protocol Number: BN43118 Start Date: 2022-06-24
Sponsor Name: Roche Farma S. A. U. que realiza el ensayo en España y que actúa como representante F. Hoffmann-La Roche Ltd
Full Title: A PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CROVALIMAB IN PATIENTS WITH GUILLAIN-BARRÉ S...
Medical condition: Guillain-Barré syndrome (GBS)
Disease: Version SOC Term Classification Code Term Level
22.1 10029205 - Nervous system disorders 10018767 Guillain-Barre syndrome PT
21.1 10029205 - Nervous system disorders 10018766 Guillain Barre syndrome LLT
21.1 10029205 - Nervous system disorders 10042812 Syndrome Guillain-Barre LLT
Population Age: Adults, Elderly Gender: Male, Female
Trial protocol: ES (Ongoing)
Trial results: (No results available)