Senior Scientist / Associate Research Scientist - Synthetic Organic Chemistry

Submission for the position: Senior Scientist / Associate Research Scientist - Synthetic Organic Chemistry - (Job Number: 188231)

In labs and health care facilities worldwide – HERE WE ARE

PPD is a leading global contract research organization providing comprehensive, integrated drug development, laboratory and lifecycle management services.  At PPD, we are passionate, deliberate, and driven by our purpose- to improve health!  

PPD Laboratories offers the most comprehensive set of laboratory services available in the industry and continues to deliver innovative solutions to our clients through our collaborative approach, including PPD® Laboratories FSP. PPD® Laboratories FSP is a unique partnership that allows our clients to leverage the experience of our PPD staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits/advantages of being a part of PPD.

As a Senior Scientist / Associate ResearchScientist, you will join our process chemistry group in Boston, MA. This role will support drug substance development programs at the client site performing synthetic organic chemistry in the laboratory at a high level to design and execute syntheses of challenging compounds, troubleshoot a diverse range of chemistry issues and devise corrective solutions, and analyze complex data sets that leads to clear conclusion or recommendations to guide the project decision. In addition, the individual is expected to work both independently and in a matrix team environment.

Major Responsibilities: Designs, executes, and interprets synthetic organic experiments with a high degree of reliability, independence, and attention to detail Proficient in application and utility of a variety of analytical methods (NMR, HPLC, LCMS, Biotage) to monitor and analyze experiments Generate effective hypotheses to pursue synthesis goals and set new experimental direction Multitask to execute multiple experiments in an efficient manner Develops novel and creative solutions to overcome synthetic and manufacturing obstacles Maintains accurate records of experiments and results in a laboratory notebook and authors reports as assigned Draft, review and submit required documentation pertaining to the development and preparation of drug substances under cGMP environment Be familiar with SOPs and GMPs and ensure compliance with all applicable regulations and SOPs Possess excellent written and verbal communication skills Perform other duties as assigned

At PPD we hire the best, develop ourselves and each other, and recognize the power of being one team. We offer continued career advancement opportunities, award winning training and benefits focused on the health and wellbeing of our employees.  

In labs and health care facilities worldwide – HERE WE ARE

PPD is a leading global contract research organization providing comprehensive, integrated drug development, laboratory and lifecycle management services.  At PPD, we are passionate, deliberate, and driven by our purpose- to improve health!  

PPD Laboratories offers the most comprehensive set of laboratory services available in the industry and continues to deliver innovative solutions to our clients through our collaborative approach, including PPD® Laboratories FSP. PPD® Laboratories FSP is a unique partnership that allows our clients to leverage the experience of our PPD staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits/advantages of being a part of PPD.

As a Senior Scientist / Associate ResearchScientist, you will join our process chemistry group in Boston, MA. This role will support drug substance development programs at the client site performing synthetic organic chemistry in the laboratory at a high level to design and execute syntheses of challenging compounds, troubleshoot a diverse range of chemistry issues and devise corrective solutions, and analyze complex data sets that leads to clear conclusion or recommendations to guide the project decision. In addition, the individual is expected to work both independently and in a matrix team environment.

Major Responsibilities: Designs, executes, and interprets synthetic organic experiments with a high degree of reliability, independence, and attention to detail Proficient in application and utility of a variety of analytical methods (NMR, HPLC, LCMS, Biotage) to monitor and analyze experiments Generate effective hypotheses to pursue synthesis goals and set new experimental direction Multitask to execute multiple experiments in an efficient manner Develops novel and creative solutions to overcome synthetic and manufacturing obstacles Maintains accurate records of experiments and results in a laboratory notebook and authors reports as assigned Draft, review and submit required documentation pertaining to the development and preparation of drug substances under cGMP environment Be familiar with SOPs and GMPs and ensure compliance with all applicable regulations and SOPs Possess excellent written and verbal communication skills Perform other duties as assigned

At PPD we hire the best, develop ourselves and each other, and recognize the power of being one team. We offer continued career advancement opportunities, award winning training and benefits focused on the health and wellbeing of our employees.  

Education and Experience:   Bachelor's degree in a Chemistry, Organic Chemistry, or equivalent and relevant formal academic / vocational qualification Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4 years). Master’s degree in Chemistry, Organic Chemistry, or equivalent with experience comparable to 2 years Ph.D. in Chemistry, Organic Chemistry, or equivalent with experience comparable to 0-2 year

In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:   Knowledge of general chemistry and separation science - HPLC and NMR Familiar with SOPs and GMPs and ensure compliance with all applicable regulations and SOPs. Ability to independently perform root cause analysis for method investigations Ability to draft CMC sections of INDs or CTAs is a plus Proven ability in drafting, reviewing and submitting required documentation pertaining to the development and preparation of drug substances under cGMP environment is desirable. Proficiency on technical operating systems Proven problem solving and troubleshooting abilities Ability to multitask to effectively manage multiple activities/projects. Proven ability in technical writing skills Time management and project management skills Good written and oral communication skills Ability to work in a collaborative work environment with a team Ability to train junior staff

Working Environment:  

PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.  Below is listed the working environment/requirements for this role: 

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.  Able to work upright and stationary and/or standing for typical working hours.   Able to lift and move objects up to 25 pounds   Able to work in non-traditional work environments.   Able to use and learn standard office equipment and technology with proficiency.   May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.  Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. 

PPD Defining Principles: 

- We have a strong will to win - We earn our customer’s trust - We are gamechangers - We do the right thing - We are one PPD - 

If you resonate with our five principles above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, then please submit your application – we’d love to hear from you

Education and Experience:   Bachelor's degree in a Chemistry, Organic Chemistry, or equivalent and relevant formal academic / vocational qualification Previous experience that provides the knowledge, skills, and abilities to perform the job (comparable to 4 years). Master’s degree in Chemistry, Organic Chemistry, or equivalent with experience comparable to 2 years Ph.D. in Chemistry, Organic Chemistry, or equivalent with experience comparable to 0-2 year

In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:   Knowledge of general chemistry and separation science - HPLC and NMR Familiar with SOPs and GMPs and ensure compliance with all applicable regulations and SOPs. Ability to independently perform root cause analysis for method investigations Ability to draft CMC sections of INDs or CTAs is a plus Proven ability in drafting, reviewing and submitting required documentation pertaining to the development and preparation of drug substances under cGMP environment is desirable. Proficiency on technical operating systems Proven problem solving and troubleshooting abilities Ability to multitask to effectively manage multiple activities/projects. Proven ability in technical writing skills Time management and project management skills Good written and oral communication skills Ability to work in a collaborative work environment with a team Ability to train junior staff

Working Environment:  

PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.  Below is listed the working environment/requirements for this role: 

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.  Able to work upright and stationary and/or standing for typical working hours.   Able to lift and move objects up to 25 pounds   Able to work in non-traditional work environments.   Able to use and learn standard office equipment and technology with proficiency.   May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.  Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. 

PPD Defining Principles: 

- We have a strong will to win - We earn our customer’s trust - We are gamechangers - We do the right thing - We are one PPD - 

If you resonate with our five principles above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, then please submit your application – we’d love to hear from you Submission for the position: Senior Scientist / Associate Research Scientist - Synthetic Organic Chemistry - (Job Number: 188231)