- ICH GCP
- Registre américain des essais cliniques
- Essai clinique NCT01732887
Evaluating Short-term Effects of Computerized Brain Fitness Exercises in Adult Cochlear Implant and/or Hearing Aid Users
Evaluating Short-term Effects of Home-based Computerized Multi-domain Cognitive Training in Adult Cochlear Implant and/or Hearing Aid Users: A Prospective Randomized Intervention Study
Aperçu de l'étude
Statut
Les conditions
Intervention / Traitement
Description détaillée
Aural rehabilitation is a life long process in spite of advanced innovative implant technology. Existing standard therapy is inadequate for some people, because even after years of surgery many implant users does not obtain significant benefits, like improved understanding of spoken sentences. In many cases it seems that the speech comprehension deficits are linked to particular cognitive functions in cochlear implant users, including memory and attention. In this study we will test whether a computer-based set of "cognitive fitness" or "brain training" games designed to improve memory and attention will help cochlear implant and hearing aid users to understand speech better.
Cochlear implant and hearing aid users will complete 10 weeks of computer-based cognitive training on their home computers. Half of participants will do this training immediately after being enrolled in the study; the other half will receive the training beginning 10 weeks after they are enrolled. Speech comprehension and cognitive abilities will be assessed at baseline, 10, 20 and 30 weeks in all participants.
Type d'étude
Inscription (Réel)
Phase
- N'est pas applicable
Contacts et emplacements
Lieux d'étude
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Nova Scotia
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Halifax, Nova Scotia, Canada, B3H 4R2
- NeuroCognitive Imaging Lab, Dalhousie University
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Critères de participation
Critère d'éligibilité
Âges éligibles pour étudier
Accepte les volontaires sains
Sexes éligibles pour l'étude
La description
Inclusion Criteria:
- Adult cochlear implant users, and/or people with moderate/severe hearing loss using bilateral hearing aids, aged 19 or above
- Access to an internet-connect device that supports flash, and basic computer skills
- Medically stable patients
Exclusion Criteria:
- Patients with epilepsy, severe visual and cognitive difficulties, chronic fatigue syndrome, and serious co-morbid conditions which could be exacerbated by the computer training games will be excluded for safety reasons.
- Patients who are unlikely to adhere to the intervention due to dementia, Parkinson's disease, Parkinson-plus syndrome, movement disorders or disability that would impair the person's ability to perform the training (e.g., problems with attention, alertness, or learning disorders)
- Participants who cannot speak English (since study materials are only in English), or unable to give consent.
Plan d'étude
Comment l'étude est-elle conçue ?
Détails de conception
- Objectif principal: Traitement
- Répartition: Randomisé
- Modèle interventionnel: Affectation croisée
- Masquage: Aucun (étiquette ouverte)
Armes et Interventions
Groupe de participants / Bras |
Intervention / Traitement |
---|---|
Autre: Immediate cognitive fitness training
After the initial baseline evaluation, the immediate treatment group participants will receive individualized multi-domain cognitive training and standard of care.
Cognitive training includes at least 1/2 hour per session, 3 days per week, throughout the 10 week interval.
After 10 weeks of cognitive fitness training, participants in this group will switch to a 20 week "no intervention" period where they receive only standard of care treatment.
|
Computer-based training of basic cognitive functions. It has activities under two headings,
Each individual session in both groups will include playing specific computer games for at least 1/2 hour a day, 3 days per week, throughout the 10 week interval. |
Autre: Delayed cognitive fitness training
After the initial baseline evaluation, the delayed cognitive fitness training group participants will receive only standard of care for 10 weeks ("no intervention" period).
Starting in week 11, participants in this arm will receive individualized multi-domain cognitive training and standard of care.
Cognitive training includes at least 1/2 hour per session, 3 days per week, throughout the 10 week interval.
After 10 weeks of cognitive fitness training, participants will go for another 10 weeks with only standard of care treatment.
|
Computer-based training of basic cognitive functions. It has activities under two headings,
Each individual session in both groups will include playing specific computer games for at least 1/2 hour a day, 3 days per week, throughout the 10 week interval. |
Que mesure l'étude ?
Principaux critères de jugement
Mesure des résultats |
Description de la mesure |
Délai |
---|---|---|
AzBio Sentence test - change in score from baseline to post-training
Délai: Baseline, Weeks 10, 20 and 30
|
Sentences are played along with masking noise (multi-talker babble).
Participants must repeat each sentence as they heard it.
Accuracy in repeating the sentences is the outcome measure.
|
Baseline, Weeks 10, 20 and 30
|
Mesures de résultats secondaires
Mesure des résultats |
Description de la mesure |
Délai |
---|---|---|
Change from Baseline in CANTABeclipse for clinical trials
Délai: Baseline, Weeks 10, 20 and 30
|
It is a method of assessing the brain-functions of a person using computerized non-linguistic tests by touch screen technology making it rapid and safe.
It has been widely used globally to assess brain-functions in more than 100 disorders.
More than 700 articles have been published using CANTABeclipse by over 500 academic institutions or industry researchers in 60 different countries.
Tasks are performed by touch screen technology.
It assesses brain-functions such as planning, problem solving, working memory etc.
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Baseline, Weeks 10, 20 and 30
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Change from Baseline in Speech Spatial Qualities questionnaire
Délai: Baseline, Weeks 10, 20 and 30
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The Spatial Speech Qualities of Hearing scale questionnaire (SSQ; Gatehouse & Noble, 2004) is used to assess the self reported hearing disabilities across several domains such as hearing speech in challenging contexts and to the directional, distance and movement components of spatial hearing.
|
Baseline, Weeks 10, 20 and 30
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Change from Baseline in CogniFit NeuroPsychological Assessment
Délai: Baseline, Weeks 10, 20 and 30
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The CogniFit Neuropsychological assessment is a multi domain cognitive task.
It measures 18 cognitive abilities such as visuospatial working memory, visuospatial learning, focused attention, updating, monitoring etc. (Haimov et al., 2008; Peretz et al., 2011b; Shatil et al., 2010; Verghese et al., 2010)
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Baseline, Weeks 10, 20 and 30
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Adherence record
Délai: Upto 30 weeks
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Access usage data from CogniFit website will be recorded.
Recording includes time spent on each session (start and end time), number of games played during each session
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Upto 30 weeks
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Collaborateurs et enquêteurs
Parrainer
Les enquêteurs
- Chercheur principal: Aaron Newman, PhD, Dalhousie University, Canada
- Chercheur principal: Christoph Gradmann, University of Oslo
Publications et liens utiles
Liens utiles
- NeuroCognitive Imaging Lab (NCIL) is a service of Department of Psychology at Dalhousie University, Canada. Participants visit the NCIL to complete a cognitive and hearing assessment. However, they perform the training tasks from their own homes.
- The Department of Community Medicine is primary affiliation of the Sub-Investigator, Dr. Amit Bansal. He is pursuing M.Phil International Community Health at the University of Oslo, Norway under supervision of Drs. Gradmann, Lian and Newman.
- The clinical trial is conducted at the Department of Psychology, Dalhousie University, Canada
Dates d'enregistrement des études
Dates principales de l'étude
Début de l'étude
Achèvement primaire (Réel)
Achèvement de l'étude (Réel)
Dates d'inscription aux études
Première soumission
Première soumission répondant aux critères de contrôle qualité
Première publication (Estimation)
Mises à jour des dossiers d'étude
Dernière mise à jour publiée (Estimation)
Dernière mise à jour soumise répondant aux critères de contrôle qualité
Dernière vérification
Plus d'information
Termes liés à cette étude
Mots clés
Termes MeSH pertinents supplémentaires
Autres numéros d'identification d'étude
- NCIL-CI-CF
Ces informations ont été extraites directement du site Web clinicaltrials.gov sans aucune modification. Si vous avez des demandes de modification, de suppression ou de mise à jour des détails de votre étude, veuillez contacter register@clinicaltrials.gov. Dès qu'un changement est mis en œuvre sur clinicaltrials.gov, il sera également mis à jour automatiquement sur notre site Web .
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