Principal Scientist - Autologous Gene Therapies

Pharmaceutical Product Development (PPD)

WI-Middleton-Middleton WI Research Way


Responsibilities:Coordinates all aspects of managing / method development and validation and specialty service areas within the division. Supervises and assists senior technical staff in laboratory operations such as scheduling, resource management, technical and compliance related issues.

Autologous gene therapies – expertise in navigating the CMC aspects of this work through an operations role

Experience in Gene Therapy potency Assays. Transduction / Transfection.Interfaces with clients on scientific issues, study design and project technical requirements. Plans, directs and implements improvements in systems, processes and procedures to increase efficiency, productivity, quality and technical expertise in the laboratory. Assists division director in strategic planning, business development and new technology implementation.#PPDLABS

#LI-33456501_TG1

Responsibilities:Coordinates all aspects of managing / method development and validation and specialty service areas within the division. Supervises and assists senior technical staff in laboratory operations such as scheduling, resource management, technical and compliance related issues.

Autologous gene therapies – expertise in navigating the CMC aspects of this work through an operations role

Experience in Gene Therapy potency Assays. Transduction / Transfection.Interfaces with clients on scientific issues, study design and project technical requirements. Plans, directs and implements improvements in systems, processes and procedures to increase efficiency, productivity, quality and technical expertise in the laboratory. Assists division director in strategic planning, business development and new technology implementation.#PPDLABS

#LI-33456501_TG1

Education and Experience:Bachelor's degree or equivalent and relevant formal academic / vocational qualificationPrevious experience that provides the knowledge, skills, and abilities to perform the job (comparable to 12 years’) or equivalent combination of education, training, and experience.OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 10 year)OR PhD and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 8 year)

Knowledge, Skills and Abilities:Excellent technical capabilities with analytical expertise in method development and/or specialty technologyEffective written and oral communication skills as well as presentation skillsDemonstrated coaching and mentoring skillsProven problem solving and troubleshooting abilitiesAbility to drive implementation of new systems or enhance existing onesProven ability to implement change based on analysis of root causes, need, and experience and drive cross-function SOP changesStrong organizational agility and demonstrated drive for resultsKnowledge of budgeting, forecasting and fiscal managementProven ability to identify and implement common efficiencies across multiple programs/projects

Working Conditions:Work is performed in a laboratory and/or a clinical environment with exposure to electrical office equipment.Occasional drives to site locations, occasional domestic travel. Exposure to biological fluids with potential exposure to infectious organisms.Rare exposure to skin and lung irritants, radiation, toxic materials and hazardous waste.Personal protective equipment required such as protective eyewear, garments and gloves. Exposure to fluctuating and/or extreme temperatures on rare occasions.

Physical Requirements:Ability to work in an upright and /or stationary position for 6-8 hours per day. Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment. Occasional mobility needed. Occasional crouching, stooping, with frequent bending and twisting of upper body and neck.Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs.Ability to access and use a variety of computer software developed both in-house and off-the-shelf.Ability to communicate information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences.Frequently interacts with others to obtain or relate information to diverse groups. Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals. Requires multiple periods of intense concentration.Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence. Ability to perform under stress. Ability to multi-task.Regular and consistent attendance.

PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. Able to work upright and stationary and/or standing for typical working hours. Able to lift and move objects up to 25 pounds Able to work in non-traditional work environments. Able to use and learn standard office equipment and technology with proficiency. May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. Able to perform successfully under pressure while prioritizing and handling multiple projects or activities. Education and Experience:Bachelor's degree or equivalent and relevant formal academic / vocational qualificationPrevious experience that provides the knowledge, skills, and abilities to perform the job (comparable to 12 years’) or equivalent combination of education, training, and experience.OR Masters degree and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 10 year)OR PhD and previous experience that provides the knowledge, skills, and abilities to perform the job (comparable 8 year)

Knowledge, Skills and Abilities:Excellent technical capabilities with analytical expertise in method development and/or specialty technologyEffective written and oral communication skills as well as presentation skillsDemonstrated coaching and mentoring skillsProven problem solving and troubleshooting abilitiesAbility to drive implementation of new systems or enhance existing onesProven ability to implement change based on analysis of root causes, need, and experience and drive cross-function SOP changesStrong organizational agility and demonstrated drive for resultsKnowledge of budgeting, forecasting and fiscal managementProven ability to identify and implement common efficiencies across multiple programs/projects

Working Conditions:Work is performed in a laboratory and/or a clinical environment with exposure to electrical office equipment.Occasional drives to site locations, occasional domestic travel. Exposure to biological fluids with potential exposure to infectious organisms.Rare exposure to skin and lung irritants, radiation, toxic materials and hazardous waste.Personal protective equipment required such as protective eyewear, garments and gloves. Exposure to fluctuating and/or extreme temperatures on rare occasions.

Physical Requirements:Ability to work in an upright and /or stationary position for 6-8 hours per day. Repetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipment. Occasional mobility needed. Occasional crouching, stooping, with frequent bending and twisting of upper body and neck.Light to moderate lifting and carrying (or otherwise moves) objects including luggage and laptop computer with a maximum lift of 15-20 lbs.Ability to access and use a variety of computer software developed both in-house and off-the-shelf.Ability to communicate information and ideas so others will understand; with the ability to listen to and understand information and ideas presented through spoken words and sentences.Frequently interacts with others to obtain or relate information to diverse groups. Works independently with little guidance or reliance on oral or written instructions and plans work schedules to meet goals. Requires multiple periods of intense concentration.Performs a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrence. Ability to perform under stress. Ability to multi-task.Regular and consistent attendance.

PPD values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:

Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner. Able to work upright and stationary and/or standing for typical working hours. Able to lift and move objects up to 25 pounds Able to work in non-traditional work environments. Able to use and learn standard office equipment and technology with proficiency. May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments. Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.


2020-10-30 00:00:00


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