A study of GnRH agonist in pre-menopausal women with severe polycystic liver disease

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University Medical Center Groningen is starting a new clinical trial of A GnRH Agonist IN Pre-menopausal Women STudy to Treat Severe Polycystic Liver Disease.

Multicenter trial on the effect of the GnRH analogue leuprorelin on the growth of total liver volume in pre-menopausal women with very severe polycystic liver disease who, despite available therapy, experience growth and are heading for liver transplantation.

The clinical trial started in June 1, 2022 and will continue throughout October 1, 2027.

Liver growth will be primary outcome measure. Liver volumes (in % per year) measured in the MRI at screening, 6 months, 18 months, 24 months and 36 months.

For more details: https://ichgcp.net/clinical-trials-registry/NCT05478083.

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