Belgian University Hospital conducts a clinical trial of Sarcopenia and Mechanical Ventilation in Older Patients Admitted Due to COVID-19

Brugmann University Hospital is conducting the clinical trial Sarcopenia and Mechanical Ventilation in Older Patients Admitted Due to COVID-19 (SARCO-V).

The SarcoV study aims at assessing the association between sarcopenia and the indication of mechanical ventilation in older hospitalized patients due to COVID-19 infection.

Sarcopenia is disease associated with poor clinical outcomes. In critical ill chirurgical patients, sarcopenia is associated with difficult to wean of mechanical ventilation. The association between sarcopenia and mechanical ventilation is poorly studied in medical patients. COVID-19 pandemic has led a lot of medical patient to be admitted in intensive care units due to acute respiratory failure with need of mechanical ventilation support.

The primary objective is to determine if sarcopenia in critically-ill older patients with COVID-19 is associated with the indication of mechanical ventilation. Secondarily, the study aims at determining if sarcopenia is associated with difficult to wean and mortality in critically-ill older patients with COVID-19.

It is planned to include 120 participants.

Actual study start date is September 1, 2020. The researchers expect to complete the study by March 1, 2022.

Patients aged 60 and older admitted in an acute care unit of Brugmann university hospital due to COVID-19 can be enrolled into this study.

The location of the study is as follows (further details can be found here https://ichgcp.net/clinical-trials-registry/NCT04772586) Brussels, Belgium.