Cancer Center conducts a study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

Memorial Sloan Kettering Cancer Center is starting a new clinical trial of Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders.

This study will evaluate whether a geriatric assessment can lead to better treatment outcomes in older patients (age 60+) with myelodysplastic syndromes, myeloproliferative neoplasms, or related blood disorders who are going to receive chemotherapy or another treatment to prepare the body for an allogeneic hematopoietic stem cell transplant (allo-HCT). The geriatric assessment includes looking at patients' cognitive function (thinking processes), physical function, mobility (ability to move the body), mood, nutrition, and current medications to help decide the type of treatment they'll receive.

Another purpose of this study is to see whether use of the geriatric assessment improves participants' quality of life. We will evaluate participants' quality of life through questionnaires.

The clinical trial starts in February 15, 2021 and will continue throughout February 2023.

The inclusion parameters are:

  • 60 years or older
  • pathologically confirmed myelodysplastic syndrome, myeloproliferative neoplasms, or related blood disorders including chronic myelomonocytic leukemia, atypical chronic myeloid leukemia, and myelodysplastic/myeloproliferative overlapping syndrome
  • <10% blasts in bone marrow prior to transplant
  • a matched related or unrelated donor, mismatched unrelated donor, or haploidentical donor
  • meet institutional standard criteria for allogeneic transplantation as determined by the primary transplant physician

The contacts and locations are the Memoral Sloan Kettering Basking Ridge, Basking Ridge, New Jersey; Memoral Sloan Kettering Monmouth, Middletown, New Jersey; Memorial Sloan Kettering Bergen, Montvale, New Jersey; Memorial Sloan Kettering Commack, Commack, New York; Memorial Sloan Kettering Westchester, Harrison, New York; Memorial Sloan Kettering Cancer Center, New York, New York and Memorial Sloan Kettering Nassau, Uniondale, New York, United States.

For more details: https://ichgcp.net/clinical-trials-registry/NCT04761770

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