French hospital continues the work of Japanese experts in colorectal ESD

Photo by Jonathan Borba

University Hospital (Limoges, France) launched the study, which will investigate French colorectal ESD cohort in experts centers (FECCo).

Initially developed in Japan for the treatment of endemic superficial gastric cancers, endoscopic submucosal dissection (ESD) allows resection of pre-neoplastic and neoplastic lesions of the digestive tract into a single fragment. It allows a perfect pathological analysis, and decreases the rate of recurrence of the adenoma to less than 2%. However, this procedure, which is technically more challenging, is also more risky and longer. Submucosal dissection is also more expensive in terms of equipment, but this difference can be offset by the cost of the high number of iterative colonoscopies required in patients who have had endoscopic resection by WF-EMR.

Scientific debate is agitating the Western world 1, 2 and Japanese experts do not perform WF-EMR anymore, whereas no comparative prospective study has compared these two procedures.

A lot of centers in France performed colorectal ESD even for benign lesions and nationwide data about safety and efficiency is required to confirm the place of ESD for treatment of large superficial colorectal lesions.

This observational study started on January 1, 2020 and University Hospital plans to enroll 1500 participants.

The list of conditions is outlined below:

  • Cancer Colorectal
  • Polyps Colorectal
  • Endoscopic Submucosal Resection

The study location is CHU de LIMOGES (Limoges, France, 87045).

University Hospital, Limoges is a public health facility in Limousin, the largest in the region, opened in 1975, linked to the University of Limoges (faculty of medicine and faculty of pharmacy).

The link to the study details: https://ichgcp.net/clinical-trials-registry/NCT04592003

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