French University Hospital starts a clinical trial of Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection

University Hospital, Clermont-Ferrand is enrolling patients into the clinical trial investigating of Muscular Rehabilitation by Eccentric Exercise After Severe COVID-19 Infection (CovExc).

With the COVID-19 pandemic, the number of patients to be treated in rehabilitation increased .

Hospitalization for severe infection can induce muscular atrophy and muscular dysfunction that persists for several months and rehabilitation capacities may be exceeded.

Exercises in eccentric mode could be performed, inducing greater muscular hypertrophy, muscle strength, power and speed than concentric exercises.

The goal of this study was to compare functional recovery at 2 months after a training program in eccentric and concentric mode after severe COVID-19.

An effective rehabilitation could help reduce costs and duration of care.

The trial is designed to enroll male and female 18 years to 80 years and is being conducted in the CHU de Clermont-Ferrand, Clermont-Ferrand; CHU de Dijon, Dijon, France; CHU de Grenoble, Grenoble; Centre Médico-Chirurgical de Réadaptation (CMCR) des Massues, Lyon and CHU de Saint-Etienne, Saint-Étienne, France.

The study start date is June 5, 2020.

The patients that can be enrolled into this study include:

  • Diagnosed for SARS-CoV-2 infection (COVID-19) requiring a rehabilitation program at least 1 month after the hospitalization.
  • Autonomy in daily life activities 1 month after diagnosis.
  • Able to walk for 6 min (discontinuous walking possible).

This page provides a more detailed overview of this clinical trial:

https://ichgcp.net/clinical-trials-registry/NCT04649086

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